Functional coherence of molecular networks in bioinformatics:
Gespeichert in:
| Weitere Verfasser: | |
|---|---|
| Format: | Buch |
| Sprache: | German |
| Veröffentlicht: |
New York [u.a.]
Springer
2012
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Literaturangaben |
| Beschreibung: | X, 228 S. Ill., graph. Darst. |
| ISBN: | 9781461403197 |
Internformat
MARC
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Datensatz im Suchindex
| _version_ | 1804148562639978496 |
|---|---|
| adam_text | Contents
1
Introduction
to Network Biology
........................................... 1
Mehmet Koyutürk,
Shankar Subramaniam, and Ananth Grama
2
Topological Characteristics of Molecular Networks
..................... 15
Tijana
Milenković
and
Nataša Pržulj
3
Function Annotation in Gene Networks
................................... 49
Petko Bogdanov, Kathy
Macropol,
and Ambuj K. Singh
4
Proteome Network Emulating Models
..................................... 69
Phuong
Dao,
Fereydoun Hormozdiari,
Iman Hajirasouliha,
Martin Ester, and S. Cenk Sahinalp
5
Biological Network Alignment
.............................................. 97
Shahin Mohammadi and Ananth Grama
6
Pattern Mining Across Many Massive Biological Networks
............ 137
Wenyuan Li, Haiyan Hu, Yu Huang, Haifeng Li, Michael
R.
Mehan, Juan Nunez-Iglesias, Min Xu,
Xifeng Yan,
and Xianghong Jasmine Zhou
7
Molecular Networks and Complex Diseases
.............................. 171
Mehmet Koyutürk,
Sinan
Érten, Salim
A. Chowdhury,
Rod K.
Nibbe, and Mark R. Chance
8
Moving Toward Genome-Scale Kinetic Models: The Mass
Action Stoichiometric Simulation Approach
.............................. 201
Aarash Bordbar and
Bernhard
0.
Palsson
Index
............................................................................... 221
Mehmet
Koyuffirk
■ Shankar Subramaniam ■ Ananth
Grama
Editors
Functional Coherence of Molecular Networks in Bioinformatics
A fundamental problem in life sciences is the characterization of biological function.
In medical sciences, understanding the bases of functional anomalies holds the key
to effective diagnosis, treatment, and prognosis; in genetics, functional annotation of
genetic variability uncovers the complex relationship between genotype and phenotype;
in evolutionary biology, functional differences between diverse organisms highlight
the evolutionary mechanisms that underlie the complexity of biological systems. With
the successful completion of the human genome project and recent technological
advances in biological data collection, it has become possible to study biological function
from a systems perspective. Today, Systems Biology is established as a fundamental
interdisciplinary science, which focuses on the systematic study of complex mechanisms
that orchestrate the cooperation between diverse molecules that compose life.
In the study of biological systems, the complex interactions between
biomołecułes
are
often abstracted using network models. Molecular networks provide descriptions of the
organization of various biological processes, including cellular signaling, metabolism,
and genetic regulation. Knowledge on molecular networks provides the basis for systems
level analysis of biological function. Research and method development for such analyses
has grown tremendously in the past few years. This volume
provides
a detailed overview
of existing knowledge on the functional characterization of biological networks. In eight
chapters authored by an international group of systems biology and bioinformatics
researchers, functional coherence of molecular networks is comprehensively explored
from various perspectives, including network topology, modularity, functional inference,
evolution, phenotype, disease, network dynamics, and molecular kinetics.
|
| any_adam_object | 1 |
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| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.33 |
| dewey-search | 572.33 |
| dewey-sort | 3572.33 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| format | Book |
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| isbn | 9781461403197 |
| language | German |
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| spelling | Functional coherence of molecular networks in bioinformatics Mehmet Koyutürk ..., eds. New York [u.a.] Springer 2012 X, 228 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Bioinformatik (DE-588)4611085-9 gnd rswk-swf Netzwerk (DE-588)4171529-9 gnd rswk-swf Bioinformatik (DE-588)4611085-9 s Netzwerk (DE-588)4171529-9 s DE-604 Koyutürk, Mehmet edt Erscheint auch als Online-Ausgabe 978-1-4614-0320-3 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024541468&sequence=000005&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=024541468&sequence=000006&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
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| subject_GND | (DE-588)4611085-9 (DE-588)4171529-9 |
| title | Functional coherence of molecular networks in bioinformatics |
| title_auth | Functional coherence of molecular networks in bioinformatics |
| title_exact_search | Functional coherence of molecular networks in bioinformatics |
| title_full | Functional coherence of molecular networks in bioinformatics Mehmet Koyutürk ..., eds. |
| title_fullStr | Functional coherence of molecular networks in bioinformatics Mehmet Koyutürk ..., eds. |
| title_full_unstemmed | Functional coherence of molecular networks in bioinformatics Mehmet Koyutürk ..., eds. |
| title_short | Functional coherence of molecular networks in bioinformatics |
| title_sort | functional coherence of molecular networks in bioinformatics |
| topic | Bioinformatik (DE-588)4611085-9 gnd Netzwerk (DE-588)4171529-9 gnd |
| topic_facet | Bioinformatik Netzwerk |
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