Salivary gland disorders and diseases: diagnosis and management
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2011
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| Physical Description: | XVII, 486 S. zahlr. Ill., graph. Darst. |
| ISBN: | 9783131464910 3131464917 |
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| 245 | 1 | 0 | |a Salivary gland disorders and diseases |b diagnosis and management |c Patrick J. Bradley ; Orlando Guntinas-Lichius. With contributions by A. van Nieuw Amerongen ... |
| 264 | 1 | |a Stuttgart [u.a.] |b Thieme |c 2011 | |
| 300 | |a XVII, 486 S. |b zahlr. Ill., graph. Darst. | ||
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XII
Contents
Section
I Salivary Glands—Anatomy
and Evaluation
. 1
1
Embryology and Clinical Anatomy
. 3
Abigails. Tucker
Introduction
. 3
Clinical Anatomy
. 3
Embryology
. 6
2
Regulatory Mechanisms and Salivary
Gland Functions
. 10
Joergen Ekstroem, Nina Khosravani
Introduction
. 10
Functions of Saliva
. 10
Spontaneous and Reflex Secretion
. 11
Stimulus for Reflex Secretion
. 11
Salivary Centers—Facilitation and Inhibition
. 12
Efferent Pathways—
Nontraditional
Routes
. 12
Neural Control of Salivary Gland Activity
. 12
Hormonal Influences
. 15
Sensory
Innervation
. 15
Early and Late Denervation Phenomena
. 15
Gland Weight
. 15
Effects of Aging
. 16
Pharmacological Aspects
. 16
3
Evaluation of Saliva—Normal and in Disease
. 19
Enno C.I.
Veerman,
Arie
van
Nieuw Amerongen,
Arjan Vissink
Introduction
. 19
Effect of Stimulation on Ion Composition
and the Secretion Rate
. 19
Effect of Stimulation on Protein Composition
. 20
Salivary Collection Procedures
. 21
Diseases of the Salivary Glands and Saliva
. 21
Saliva as a Diagnostic Tool for Other Diseases
. 25
4
Contemporary Salivary Clinical Pathology-
Facts and Dilemmas
. 27
Julia A. Woolgar,
Asterios Triantafyllou
Introduction
. 27
Normal Structural Variations
. 27
Inflammatory Diseases
. 28
Cystic Diseases
. 31
Benign Epithelial Tumors
. 32
Malignant Epithelial Tumors
. 35
Nonepithelial Tumors and
Métastases
. 40
5
Methods of Investigation
. 42
Orlando Guntinas-Lichius
Introduction
. 42
Examining the Patient
. 42
Examining Saliva
. 42
Ultrasonography
. 43
Fine-Needle Aspiration Cytology
. 44
Sialendoscopy
. 44
Salivary Gland Biopsy
. 44
Magnetic Resonance Imaging and
Computed Tomography
. 44
Classic Sialography and
Magnetic Resonance Sialography
. 44
Salivary Gland Scintigraphy
. 45
Serologie
Examinations
. 45
6
Patient History and Clinical Examination
. 46
Claus Wittekindt
Introduction
. 46
Patient History
. 46
Clinical Examination
. 49
Ultrasonography
. 50
7
Evaluation of Salivary Glands—Imaging
. 55
Minerva Becker
Introduction
. 55
Conventional Radiography
. 55
Conventional Sialography
. 56
Radionuclide Scanning
. 57
Ultrasonography
. 58
Computed Tomography
. 60
Magnetic Resonance Imaging
. 61
MR Sialography
. 62
PET/CT
. 64
8
Fine-Needle Aspiration Cytology and
Frozen Sections in Salivary Gland Diseases
. 66
Patrick]. Bradley, Orlando Guntinas-Lichius
Introduction
. 66
Informed Consent
. 66
Equipment Required
. 67
Physician
. 67
Aspiration Techniques
. 68
Slide Preparation
. 68
Fixation Techniques
. 69
Staining Methods
. 69
Complications
. 69
Contents
XIII
Contraindications . 69
Accuracy
. 70
The Role of Frozen-Section Diagnosis
. 70
The Role of Core-Needle Biopsy
. 71
9
Diagnostic Sialendoscopy
. 73
Cyrille
Chossegros, Alain Bizeau
Introduction
. 73
Definition
. 73
Sialendoscopic Anatomy
. 73
Patient Selection for Sialendoscopy
. 74
Clinical Features
. 75
Diagnostic Work-Up
. 75
Learning Sialendoscopy
. 77
Anesthesia
. 77
Equipment
. 78
Operative Steps
. 79
Contraindications
. 82
Complications
. 82
Postoperative Care
. 83
Scope Sterilization:
Autoclave, Gas, Soaking
. 83
Section II
Pediatric
Disorders
. 85
10
Congenital and Developmental Abnormalities
. 87
Ben Hartley
Introduction
. 87
Epidemiology
. 87
Diagnostic Work-Up
. 87
Salivary Gland
Aplasia
and Duct Abnormalities
. 87
Congenital Vascular Anomalies
. 88
First Branchial Cleft Anomalies
. 90
Parapharyngeal Cysts
. 91
Pediatrie
Salivary Gland Surgery
. 91
11
Salivary Gland Neoplasms
. 93
Patrick}. Bradley, Ben Hartley
Introduction
. 93
Epidemiology and Etiology
. 93
Differential Diagnosis of Neoplasms
. 94
Clinical Features
. 95
Diagnostic Work-Up
. 96
Histopathological Differential Diagnosis
. 97
Treatment
. 97
Radiotherapy
. 98
Chemotherapy
. 99
Management of Recurrent Neoplasms
. 99
Outcomes and Prognosis
. 99
12
Drooling
. 102
Rainer
łaskawi,
Maik Ellies
Introduction
. 102
Definition
. 102
Epidemiology and Etiology
. 102
Clinical Features
. 103
Diagnostic Work-Up
. 103
Differential Diagnosis
. 103
Surgical Treatment
. 104
Nonsurgical Treatment:
Botulinum Toxin Injection
. 106
Outcome and Prognosis
. 107
13
Inflammatory and Infectious Diseases
of the Salivary Glands
. 110
Razvan
A. Tasca,
Ray Clarke
Introduction
. 110
Definition
. 110
Epidemiology and Etiology
. 110
Clinical Features
.
Ill
Diagnostic Work-Up
.
Ill
Treatment
. 113
Parenchymal Infections
. 113
Intrasalivary Lymphadenopathy
. 116
Noninfective Conditions
. 118
Section III Physiological Disorders
. 121
14
Dry Mouth and Dry Eyes
. 123
Crispían
Scully, Jane hiker, Austin McCormick
Dry Mouth—Xerostomia and Hyposalivation
. 123
Dry Eyes
. 128
15
Sialadenitis and Sialadenosis—Interventional
Sialendoscopy
. 136
Cyrille
Chossegros, Frederic
Faure,
Francis
Marchai
Introduction
. 136
Definition
. 136
Indications and Patient Selection
. 137
Diagnostic Work-Up
. 138
Contraindications
. 139
Patient Information and Consent
. 139
Anesthesia and Positioning
. 139
Equipment
. 141
Procedural Steps
. 143
Complications
. 149
Postoperative Care
. 150
XIV Contente
16
Autoimmune Disorders, Lymphoproliferation,
and Granulomatous Inflammation
. 152
Roland
Jonsson, Jan Olofsson
Introduction
. 152
Sjögren
Syndrome (Autoimmune Sialadenitis,
Mikulicz Disease, Chronic Sderosing
Sialadenitis)
. 152
MALT Lymphoma
. 158
Chronic Graft-Versus-Host Disease
. 159
Sarcoidosis
. 161
HIV
Infection
. 163
17
Cystic Salivary Gland Tumors Including
Cystic Neoplasms
. 167
Patrick J. Bradley
Introduction
. 167
Definition
. 167
Clinical Classification of Cysts
. 168
Clinical Features
. 169
Diagnostic Work-Up
. 169
Benign Salivary Cysts
. 170
Mucoceles
. 171
HIV-Associated Salivary Cysts
. 171
Branchial Cleft Cysts
. 172
Ránulas
. 172
Cystic Salivary Gland Neoplasms
. 173
Lymphoma
. 174
Neurological Neoplasms
. 174
Other Causes
. 174
Section IV Benign Salivary Gland
Neoplasms
. 177
18
Epidemiology of Benign Salivary
Gland Neoplasms
. 179
David G. Grant, Paula T. Bradley
Introduction
. 179
Etiology of Benign Salivary Gland Tumors
. 179
Classification
. 180
Data and Site Distribution
. 180
Incidence Reports of Benign Salivary Tumors
. 183
19
Etiology
. 187
Alena Skálová, Tomáš Vaněček, Ivo Stárek
Introduction
. 187
Radiation
. 187
Viruses
. 187
Other Environmental Risk Factors
. 188
Genetics
. 188
20
Classification of Benign Salivary Neoplasms
. 193
Patrick J. Bradley,
Claus Wittekindt
Introduction
. 193
Pleomorphic Adenoma
. 194
Warthin Tumor
. 195
Myoepithelioma
. 195
Basal Cell Adenoma
. 196
Oncocytoma
. 196
Canalicular Adenoma
. 196
Sebaceous Adenoma
. 197
Sebaceous and Nonsebaceous Lymphadenomas
197
Ductal Papillomas
. 197
Cystadenoma
. 198
Benign Nonepithelial Tumors
and
Tumoruké
Lesions
. 198
21
Investigation
. 200
Orlando Guntinas-Lichius
Introduction
. 200
Clinical Features
. 200
Diagnostic Work-Up
. 201
Preparation and Scheduling of Surgery
. 202
22
Surgical Management
. 203
Patrick J. Bradley, Nigel Beasley
Introduction
. 203
Surgical Anatomy of the Parotid Gland
and Parapharyngeal Space
. 203
Surgical Anatomy of the Submandibular Gland
. 208
Surgical Anatomy of the
Sublingual
Gland
. 209
Surgical Anatomy of the Minor Salivary Glands
210
Indications and Patient Selection
. 210
Patient Information and Consent
. 210
Anesthesia and Positioning
. 211
Operative Steps-Parotid Gland
. 211
Operative Steps—Submandibular Gland
. 216
Operative Steps-Sublingual Gland
. 218
Operative Steps—Minor Salivary Glands
. 219
Tips and Tricks in Salivary Surgery
. 219
Complications
. 220
Postoperative Care
. 221
Outcomes
. 221
23
Radiotherapy
. 224
Susanne].
Rogers, Christopher M. Nutting
Introduction
. 224
Clinical Presentation
. 224
Treatment
. 224
Indications and Patient Selection for Radiotherapy
225
Patient Information and Consent
. 226
Radiotherapy Treatment Technique for Electrons
226
Radiotherapy Treatment Technique for Photons
226
Radiotherapy Dose
. 228
Outcome and Prognosis
. 228
Complications and Limitations
. 230
Contents
XV
24
Recurrent Benign Salivary Tumors
. 233
Orlando Guntinas-Lichius,
C. René
Leemans,
Patrick]. Bradley
Introduction
. 233
Epidemiology and Etiology
. 233
Diagnostic Work-Up
. 234
Surgery for Benign Recurrent Disease
. 236
Operative Steps
. 239
Complications
. 241
Postoperative Care
. 242
Postoperative Radiotherapy
for Benign Recurrent Disease
. 242
Section V Malignant Salivary Gland
Neoplasms
. 245
25
Epidemiology of Malignant Salivary
Gland Neoplasms
. 247
David G. Grant, Paula T. Bradley
Introduction
. 247
General Concepts and Complexities
. 247
Problems in the Published
Epidemiological Data
. 247
Institutional Studies
. 248
Databases and Population-Based Studies
. 249
26
Etiology
. 252
Alena Skálová, Tomáš Vaněček, Ivo Stárek
Introduction
. 252
Radiation
. 252
Viruses
. 253
Lifestyle and Nutrition
. 253
Occupation
. 253
Hormones
. 253
Genetics
. 253
27
Malignant Salivary Gland Neoplasms-
Classification
. 262
Patrick]. Bradley,
Claus Wittekindt
Introduction
. 262
Histogenesis of Malignant Salivary
Gland Neoplasms
. 262
TNM and Stage Groupings
. 264
Acinic Cell Carcinoma
. 264
Mucoepidermoid Carcinoma
. 266
Adenoid Cystic Carcinoma
. 266
Polymorphous Low-Grade Adenocarcinoma
. 267
Oncocytic Carcinoma
. 267
Salivary Duct Carcinoma
. 267
Carcinoma Ex Pleomorphic Adenoma
. 268
Squamous Cell Carcinoma
. 268
Lymphoepithelial Carcinoma
. 269
Other Rare Salivary Gland Malignancies
. 269
28
Imaging Examinations
. 274
Minerva Becker
Introduction
. 274
Choice of Imaging Method
. 274
Ultrasound Features of Salivary Gland
Malignancies and Differential Diagnosis
. 275
CT Features of Salivary Gland
Malignancies and Differential Diagnosis
. 276
MR Features of Salivary Gland
Malignancies and Differential Diagnosis
. 277
Features on FDG-PET/CT
. 282
29
Surgical Management
. 285
Hans E. Eckel,
Markus ¡ungehuelsing
Introduction
. 285
Indications and Patient Selection
. 285
Choice of Surgical Procedure
. 287
Informed Consent
. 288
Anesthesia and Positioning
. 288
Surgical Steps
. 289
Postoperative Radiotherapy
. 295
Complications and Sequelae of Surgery
. 295
Measures for Specific Complications
. 296
Postoperative Care
. 296
Outcomes
. 297
Follow-Up after Curative Surgery
. 298
30
Radiotherapy
. 301
Chris HJ. Terhaard
Introduction
. 301
Patient Selection
. 301
Indications for Radiotherapy
. 304
Results of Local and Locoregional Radiotherapy
305
Radiotherapy Techniques
. 308
Future Directions
. 311
31
Chemotherapy and Novel Therapeutics
. 315
Kevin J. Harrington,
Eleni
M. Karapanagiotou
Introduction
. 315
Epidemiology and Etiology
. 315
Molecular Biology of Salivary Gland Cancer
. 315
Clinical Features
. 316
Indications and Patient Selection
. 317
Diagnostic Work-Up
. 317
Treatment
. 317
Outcomes and Prognosis
. 320
32
Neck Metastasis
. 323
Peter Zbaeren, PatrickJ. Bradley
Introduction
. 323
Prognostic Impact of Lymph-Node
Métastases
. 323
Incidence of Clinically Detectable
Neck
Métastases
. 324
Occult
Métastases
. 325
XVI
Contents
Neck
Récurrences
. 325
Treatment of the Node-Positive Neck
. 326
Treatment of the Node-Negative Neck
. 326
Neck Dissection Surgery
. 327
Complications of Neck Dissection
. 331
33
Locoregional Recurrence and Its Management
333
Orlando Guntinas-Lichius
Introduction
. 333
Epidemiology and Risk Factors for Recurrence
. 334
Diagnostic Work-Up
. 334
Surgery for Local Recurrence
. 335
Surgery for Regional Recurrence
. 339
Radiotherapy for Locoregional Recurrence
. 339
Chemotherapy or Biological Agents
for Locoregional Recurrent Disease
. 340
34
Distant
Métastases
and Management
. 341
Alessandro Franchi, Oreste Gallo
Introduction
. 341
Basic
Mechanisms of Metastasis
. 341
Clinical Features and Pathological Aspects
. 344
Follow-Up
. 346
Diagnostic Work-Up
. 346
Treatment
. 347
35
Prognostic Index for Overall Disease Control
in Patients with Parotid Carcinoma
. 350
Vincent
Vander Poorten
Introduction
. 350
Overview of Prognostic Research
. 350
Disease-Specific Survival in Patients
. 351
Results of Univariate and
Multivariate Survival Analysis
. 352
Interpretation of
Ρ
Values
. 352
Development of a Prognostic Index
for Disease Control
. 355
External Validation of the Prognostic Index
. 357
Limitations of the Current Prognostic
Index System
. 361
Future Developments in Prognostic Research
. 362
Section VI Other Topics
. 365
36
Malignant Head and Neck Tumors and
Skin Cancer Infiltrating the Parotid Glands
. 367
Afshin Teymoortash
Introduction
. 367
Parotid Lymph Nodes and Skin Cancer
. 367
Parotid Lymph-Node Metastasis
and Cervical Lymph Nodes
. 368
Risk Factors for Lymphogenic Metastasis
of Skin Cancer
. 368
Prognosis
. 369
Follow-Up in High-Risk Patients
. 370
Treatment
. 371
Merkel
Cell Carcinoma
. 371
Malignant Melanoma
. 372
Parotid Lymph-Node
Métastases
from
Noncutaneous Head and Neck Cancer
. 372
Direct Invasion of the Parotid
by Head and Neck Cancer
. 372
37
Métastases
to the Major Salivary Glands
from Non-Head and Neck Primary
Malignancies
. 374
James O'Hara, Vinidh
Valeri
Introduction
. 374
Métastases
to the Parotid Gland
. 375
Métastases
to the Submandibular Gland
. 376
38
Principles of Facial
Reanimation
Surgery
. 378
Orlando Guntinas-Lichius
Introduction
. 378
Direct Facial-Facial Nerve
Reconstruction
. 378
Facial-Facial Nerve Interpositional Graft
. 381
Hypoglossal-Facial Nerve Jump
Anastomosis and Combined Approach
. 382
Upper Eyelid Surgery
. 385
Dynamic Procedures with
Regional Muscle Transposition
. 386
Static Procedures with Slings
. 388
Free Microvascular Flaps
. 391
Adjuvant Procedures
. 391
39
Morbidity of Treatments
. 393
Orlando Guntinas-Lichius
Introduction
. 393
Transient and Permanent Facial Nerve Palsy
. 393
Salivary Fistula and Sialocele
. 394
Gustatory Sweating
. 395
Facial Depression Deformity
. 397
Scar Cosmesis
. 398
Paresthesia in the Ear Region
. 399
Lingual or Hypoglossal Nerve Injury
. 399
40
Trauma-Induced Problems
in the Salivary Glands
. 402
Vinidh Paleri, M. Shahed Quraishi
Introduction
. 402
Clinical Anatomy
. 402
Definition
. 402
Epidemiology
. 404
Clinical Features
. 404
Diagnostic Work-Up
. 404
Treatment
. 406
Late Sequelae of Injury
. 407
Contents
XVII
41
Quality of Life in Salivary Gland Diseases
. 410
Susanne
Singer
Introduction
. 410
Definition and Concept
. 410
Measurement
. 411
Specific Problems in Salivary Gland Diseases
. 414
Measures to Improve Quality of Life
. 415
42
Influence of (Chemo-jRadiotherapy
on Salivary Gland Function and
Its Impact on Quality of Life
. 419
Chris H.J. Terhaard,
Piet
Diri*
Introduction
. 419
General Aspects
. 419
Xerostomia after Radiotherapy
. 420
Dose-Response Curves
. 422
Radiation Techniques for Sparing
the Salivary Glands
. 424
Amifostine and Radiation-Induced Xerostomia
. 427
Pilocarpine
for Preserving Parotid Function
. 427
43
Salivary Gland Transplantation
. 430
Peter
Sieg, Gerd Geerling
Introduction
. 430
Definition
. 430
Physiology and Pathophysiology
. 430
Indications and Patient Selection
. 431
Diagnostic Work-Up
. 432
Patient Information and Consent
. 432
Anesthesia and Positioning
. 432
Operative Steps
. 432
Postoperative Care
. 434
Complications
. 435
Outcome
. 436
44
Salivary Gland Regeneration
and Tissue Engineering
. 439
Nicole Rotter
Introduction
. 439
Epidemiology and Etiology of Salivary
Gland Hypofunction
. 439
Morphology and Mechanisms
of Postradiotherapy Salivary Gland
Hypofunction
. 439
Current Treatment Modalities for Xerostomia
. 440
Experimental Treatments
. 441
Future Trends
. 448
45
Medicolegal Issues
. 451
Antony Wright
Introduction
. 451
Definition of Negligence
. 451
The Steps in a Medical Negligence,
Tort-Based Claim
. 453
No-Fault Compensation Schemes
. 454
DutyofCare
. 455
Standard of Care
. 455
Consent
. 456
Causation
. 458
How to Avoid Being Sued
. 459
Special Issues Concerning Salivary Gland Surgery
460
46
New Developments in Molecular Biology
. 463
Vincent
Vander Poorten
List of Abbreviations
. 463
Introduction
. 463
Recent and New Developments
. 464
Conclusions and Future Developments
. 470
Index
. 474 |
| any_adam_object | 1 |
| author_GND | (DE-588)110018998X (DE-588)1078441464 |
| building | Verbundindex |
| bvnumber | BV037399662 |
| classification_rvk | YP 5000 YP 7550 |
| ctrlnum | (OCoLC)698331058 (DE-599)DNB1010876457 |
| dewey-full | 616.316 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.316 |
| dewey-search | 616.316 |
| dewey-sort | 3616.316 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
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| id | DE-604.BV037399662 |
| illustrated | Illustrated |
| indexdate | 2024-07-20T11:08:00Z |
| institution | BVB |
| isbn | 9783131464910 3131464917 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-022552378 |
| oclc_num | 698331058 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-578 DE-29 DE-19 DE-BY-UBM |
| owner_facet | DE-355 DE-BY-UBR DE-578 DE-29 DE-19 DE-BY-UBM |
| physical | XVII, 486 S. zahlr. Ill., graph. Darst. |
| publishDate | 2011 |
| publishDateSearch | 2011 |
| publishDateSort | 2011 |
| publisher | Thieme |
| record_format | marc |
| spelling | Salivary gland disorders and diseases diagnosis and management Patrick J. Bradley ; Orlando Guntinas-Lichius. With contributions by A. van Nieuw Amerongen ... Stuttgart [u.a.] Thieme 2011 XVII, 486 S. zahlr. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Speicheldrüsenkrankheit (DE-588)4126672-9 gnd rswk-swf Speicheldrüsenkrankheit (DE-588)4126672-9 s DE-604 Bradley, Patrick J. 1949- Sonstige (DE-588)110018998X oth Guntinas-Lichius, Orlando 1967- Sonstige (DE-588)1078441464 oth X:MVB text/html http://deposit.dnb.de/cgi-bin/dokserv?id=3709593&prov=M&dok_var=1&dok_ext=htm Inhaltstext Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022552378&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Salivary gland disorders and diseases diagnosis and management Speicheldrüsenkrankheit (DE-588)4126672-9 gnd |
| subject_GND | (DE-588)4126672-9 |
| title | Salivary gland disorders and diseases diagnosis and management |
| title_auth | Salivary gland disorders and diseases diagnosis and management |
| title_exact_search | Salivary gland disorders and diseases diagnosis and management |
| title_full | Salivary gland disorders and diseases diagnosis and management Patrick J. Bradley ; Orlando Guntinas-Lichius. With contributions by A. van Nieuw Amerongen ... |
| title_fullStr | Salivary gland disorders and diseases diagnosis and management Patrick J. Bradley ; Orlando Guntinas-Lichius. With contributions by A. van Nieuw Amerongen ... |
| title_full_unstemmed | Salivary gland disorders and diseases diagnosis and management Patrick J. Bradley ; Orlando Guntinas-Lichius. With contributions by A. van Nieuw Amerongen ... |
| title_short | Salivary gland disorders and diseases |
| title_sort | salivary gland disorders and diseases diagnosis and management |
| title_sub | diagnosis and management |
| topic | Speicheldrüsenkrankheit (DE-588)4126672-9 gnd |
| topic_facet | Speicheldrüsenkrankheit |
| url | http://deposit.dnb.de/cgi-bin/dokserv?id=3709593&prov=M&dok_var=1&dok_ext=htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022552378&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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