Principles of molecular virology:
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Amsterdam [u.a.]
Elsevier, Acad. Press
2012
|
| Edition: | 5. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Literaturangaben |
| Physical Description: | IX, 303 S. Ill., graph. Darst. |
| ISBN: | 9780123849397 012384939X |
Staff View
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| 245 | 1 | 0 | |a Principles of molecular virology |c Alan J. Cann |
| 250 | |a 5. ed. | ||
| 264 | 1 | |a Amsterdam [u.a.] |b Elsevier, Acad. Press |c 2012 | |
| 300 | |a IX, 303 S. |b Ill., graph. Darst. | ||
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Record in the Search Index
| _version_ | 1804145679139864576 |
|---|---|
| adam_text | Contents
PREFACE
TO THE FIFTH EDITION
..........................................................ix
CHAPTER
1
CHAPTER
2
CHAPTERS
Introduction
...................................
What Are Viruses?
..............................
Are viruses alive?
...........................
The History of Virology
...................
Living Host Systems
Cell Culture Methods
Serological/lmmunological Methods
Ultrastructural
Studies
........
Molecular Biology
Summary
....................
... 1
...2
3
4
6
8
10
11
18
23
Particles
..............................................................................25
The Function and Formation of Virus Particles
......................25
Capsid symmetry and virus architecture
..............................27
Helical capsids
..........................................................................28
Icosahedral (isometric) capsids
..............................................33
Enveloped viruses
....................................................................39
Complex virus structures
........................................................42
Protein-nucleic acid interactions and genome
packaging
.............................................................................48
Virus receptors: recognition and binding
.............................52
Other interactions of the virus capsid with the host cell
.... 53
Summary
........................................................................................53
Genomes
.............................................................................55
The Structure and Complexity of Virus Genomes
55
Molecular genetics
............................................. 57
Vims genetics
.............. ...................................61
Virus mutants
.........................................................................63
Genetic interactions between viruses
...................................66
Nongenetic interactions between viruses
............................69
Small
DNA
genomes................................................................
70
Large
DNA
genomes
................................................................75
Positive-strand RNA
viruses
...................................................78
Negative-strand RNA
viruses.................................................
81
Segmented and multipartite virus genomes
.........................84
Reverse transcription and transposition
...............................88
Evolution and epidemiology
....................................................97
Summary
......................................................................................100
CHAPTER
4
Replication
........................................................................103
Overview of Vims Replication
..................................................103
Investigation of
Viras
Replication
............................................105
The Replication Cycle
................................................................109
Attachment
..............................................................................110
Penetration
..............................................................................117
Uncoating
................................................................................118
Genome replication and gene expression
...........................121
Assembly
.................................................................................125
Maturation
...............................................................................127
Release
.....................................................................................129
Summary
......................................................................................131
CHAPTER
5
Expression
........................................................................133
Expression of Genetic Information
...........................................133
Control of Prokaryote Gene Expression
...................................134
Control of Expression in Bacteriophage
λ
...............................135
Control of Eukaryote Gene Expression
....................................140
Genome Coding Strategies
........................................................142
Class I: Double-stranded
DNA..............................................143
Class
Π:
Single-stranded
DNA..............................................145
Class
Ш:
Double-stranded
RNA
...........................................146
Class IV: Single-stranded (+)sense
RNA
.............................148
Class V: Single-stranded (-)sense
RNA
..............................151
Class VI: Single-stranded (+)sense
RNA
with
DNA
intermediate
............................................................................153
Class
Vu:
Double-stranded
DNA
with
RNA
intermediate
.......................................................................153
Transcriptional Control of Expression
.....................................154
Posttranscriptional Control of Expression
...............................158
Summary
......................................................................................167
CHAPTER
6
Infection
............................................................................169
Virus Infections of Plants
...........................................................169
Immune Responses to Virus Infections in Animals
...............174
Contents
CHAPTER
7
CHAPTER
8
Virases
and Apoptosis
...............................................................179
Interferons...................................................................................181
Evasion of Immune Responses by Viruses
.............................186
Inhibition of MHC-I-restricted antigen presentation
.........186
Inhibition of MHC-n-restricted antigen presentation
........187
Inhibition of natural killer cell lysis
......................................187
Interference with apoptosis
..................................................187
Inhibition of cytokine action
..................................................187
Evasion of humoral immunity
...............................................188
Evasion of the complement cascade
....................................188
Virus-Host Interactions
............................................................188
The Course of Virus Infections
.................................................196
Abortive infection
...................................................................196
Acute infection
........................................................................198
Chronic infection
....................................................................198
Persistent infection
................................................................198
Latent infection
.......................................................................200
Prevention and Therapy of Virus Infection
.............................201
RNA
Interference (RNAi)
...........................................................205
Virus Vectors and Gene Therapy
.............................................206
Chemotherapy of Virus Infections
............................................208
Summary
......................................................................................213
Pathogenesis
....................................................................215
Mechanisms of Cellular Injury
..................................................216
Viruses and Immunodeficiency
................................................220
Vims-Related Diseases
..............................................................224
Bacteriophages and Human Disease
.......................................227
Cell Transformation by Viruses
................................................228
Cell Transformation by Retrovirases
.......................................232
Cell Transformation by
DNA
Viruses
.......................................235
Viruses and Cancer
....................................................................238
New and Emergent Viruses
......................................................243
Zoonoses
......................................................................................250
Bioterrorism
.................................................................................251
Summary
......................................................................................252
Subviral
Agents: Genomes without Viruses,
Viruses without Genomes
..............................................255
Satellites and Viroids
.................................................................255
Prions
...........................................................................................259
Pathology of prion diseases
..................................................260
TSE in Animals
...........................................................................260
Scrapie
.....................................................................................260
Transmissible mink encephalopathy
(TME).......................
262
Feline spongiform encephalopathy
(FSE)
............................262
Chronic wasting disease (CWD)
...........................................262
Bovine spongiform encephalopathy (BSE)
..........................263
Human TSEs
................................................................................264
Molecular Biology of
Prions
.......................................................267
Summary
......................................................................................272
APPENDIX
1:
GLOSSARY AND ABBREVIATIONS
...............................275
APPENDIX
2:
CLASSIFICATION OF SUBCELLULAR
INFECTIOUS AGENTS
.....................................................285
APPENDIX
3:
THE HISTORY OF VIROLOGY
........................................291
INDEX
.........................................................................................................297
|
| any_adam_object | 1 |
| author | Cann, Alan ca. 20./21. Jh |
| author_GND | (DE-588)1089177542 |
| author_facet | Cann, Alan ca. 20./21. Jh |
| author_role | aut |
| author_sort | Cann, Alan ca. 20./21. Jh |
| author_variant | a c ac |
| building | Verbundindex |
| bvnumber | BV037390284 |
| callnumber-first | Q - Science |
| callnumber-label | QR389C35 1993 |
| callnumber-raw | QR389C35 1993 |
| callnumber-search | QR389C35 1993 |
| callnumber-sort | QR 3389 C35 41993 |
| callnumber-subject | QR - Microbiology |
| classification_rvk | WF 3000 XD 7000 |
| ctrlnum | (OCoLC)729927196 (DE-599)BVBBV037390284 |
| dewey-full | 579.2 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 579 - Microorganisms, fungi & algae |
| dewey-raw | 579.2 |
| dewey-search | 579.2 |
| dewey-sort | 3579.2 |
| dewey-tens | 570 - Biology |
| discipline | Biologie Medizin |
| edition | 5. ed. |
| format | Book |
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| genre | 1\p (DE-588)4151278-9 Einführung gnd-content |
| genre_facet | Einführung |
| id | DE-604.BV037390284 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T23:23:17Z |
| institution | BVB |
| isbn | 9780123849397 012384939X |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-022543189 |
| oclc_num | 729927196 |
| open_access_boolean | |
| owner | DE-11 DE-20 DE-355 DE-BY-UBR DE-29 DE-29T DE-578 DE-19 DE-BY-UBM |
| owner_facet | DE-11 DE-20 DE-355 DE-BY-UBR DE-29 DE-29T DE-578 DE-19 DE-BY-UBM |
| physical | IX, 303 S. Ill., graph. Darst. |
| publishDate | 2012 |
| publishDateSearch | 2012 |
| publishDateSort | 2012 |
| publisher | Elsevier, Acad. Press |
| record_format | marc |
| spelling | Cann, Alan ca. 20./21. Jh. Verfasser (DE-588)1089177542 aut Principles of molecular virology Alan J. Cann 5. ed. Amsterdam [u.a.] Elsevier, Acad. Press 2012 IX, 303 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Literaturangaben Maladies virales Maladies à virus - Aspect moléculaire ram Virologie moléculaire Virologie moléculaire ram Virologie Virus - Aspect moléculaire ram Molekularbiologie (DE-588)4039983-7 gnd rswk-swf Molekulargenetik (DE-588)4039987-4 gnd rswk-swf Viren (DE-588)4063589-2 gnd rswk-swf Molekulare Virologie (DE-588)4170393-5 gnd rswk-swf Virologie (DE-588)4063597-1 gnd rswk-swf 1\p (DE-588)4151278-9 Einführung gnd-content Viren (DE-588)4063589-2 s Molekulargenetik (DE-588)4039987-4 s DE-604 Molekularbiologie (DE-588)4039983-7 s Molekulare Virologie (DE-588)4170393-5 s Virologie (DE-588)4063597-1 s 2\p DE-604 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022543189&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Cann, Alan ca. 20./21. Jh Principles of molecular virology Maladies virales Maladies à virus - Aspect moléculaire ram Virologie moléculaire Virologie moléculaire ram Virologie Virus - Aspect moléculaire ram Molekularbiologie (DE-588)4039983-7 gnd Molekulargenetik (DE-588)4039987-4 gnd Viren (DE-588)4063589-2 gnd Molekulare Virologie (DE-588)4170393-5 gnd Virologie (DE-588)4063597-1 gnd |
| subject_GND | (DE-588)4039983-7 (DE-588)4039987-4 (DE-588)4063589-2 (DE-588)4170393-5 (DE-588)4063597-1 (DE-588)4151278-9 |
| title | Principles of molecular virology |
| title_auth | Principles of molecular virology |
| title_exact_search | Principles of molecular virology |
| title_full | Principles of molecular virology Alan J. Cann |
| title_fullStr | Principles of molecular virology Alan J. Cann |
| title_full_unstemmed | Principles of molecular virology Alan J. Cann |
| title_short | Principles of molecular virology |
| title_sort | principles of molecular virology |
| topic | Maladies virales Maladies à virus - Aspect moléculaire ram Virologie moléculaire Virologie moléculaire ram Virologie Virus - Aspect moléculaire ram Molekularbiologie (DE-588)4039983-7 gnd Molekulargenetik (DE-588)4039987-4 gnd Viren (DE-588)4063589-2 gnd Molekulare Virologie (DE-588)4170393-5 gnd Virologie (DE-588)4063597-1 gnd |
| topic_facet | Maladies virales Maladies à virus - Aspect moléculaire Virologie moléculaire Virologie Virus - Aspect moléculaire Molekularbiologie Molekulargenetik Viren Molekulare Virologie Einführung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022543189&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT cannalan principlesofmolecularvirology |