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Nanopore analytics: electro-optical studies on single molecules

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Bibliographic Details
Main Author:	Pedone, Daniel Claudio (Author)
Format:	Thesis Book
Language:	English
Published:	Garching Verein zur Förderung des Walter-Schottky-Inst. der Techn. Univ. München 2011
Edition:	1. Aufl.
Series:	Selected topics of semiconductor physics and technology 126
Subjects:	Pore Molekül Halbleiter Nanometerbereich Chemischer Sensor Hochschulschrift
Online Access:	Inhaltsverzeichnis
Physical Description:	X, 114 S. Ill., graph. Darst. 21 cm
ISBN:	9783941650268

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MARC


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adam_text	CONTENTS ABSTRACT...................................................................................................................................................... V ZUSAMMENFASSUNG ................................................................................................................................... VII 1 INTRODUCTION - NANOPORE ANALYTICS ...................................................................................................... 1 2 NANOPORE FABRICATION TECHNIQUES....................................................................................................... 7 2.1 ELECTRON BEAM LITHOGRAPHY .......................................................................................................... 10 2.2 TEM INDUCED SHRINKING .................................................................................................................. 12 2.3 TEM DRILLING ................................................................................................................................... 13 2.4 FOCUSED ION BEAM DRILLING ............................................................................................................ 14 2.5 PORE-CAVITY-PORE DEVICE FABRICATION ............................................................................................ 16 3 ELECTRICAL CHARACTERIZATION .................................................................................................................. 23 4 SENSING SINGLE DNA MOLECULES WITH A SOLID-STATE NANOPORE.......................................................... 31 5 SENSING SINGLE PROTEINS WITH A SOLID-STATE NANOPORE ..................................................................... 41 5.1 DATA ANALYSIS OF RAPID TRANSLOCATION EVENTS IN NANOPORE EXPERIMENTS ..................................... 42 5.2 DETECTION OF SINGLE PROTEINS AND PROTEIN SIZE DISCRIMINATION USING A SOLID-STATE NANOPORE ... 51 5.3 ELECTROKINETICALLY FACILITATED TRANSPORT OF PROTEINS THROUGH SOLID-STATE NANOPORES .............. 58 6 SENSING SINGLE DNA MOLECULES WITH THE PORE-CAVITY-PORE DEVICE ................................................... 63 6.1 ELECTRICAL DETECTION OF SINGLE DNA MOLECULES WITH A PORE-CAVITY-PORE DEVICE ......................... 64 6.2 SYNCHRONOUS OPTICAL AND ELECTRICAL DETECTION OF SINGLE DNA MOLECULES WITH A PORE-CAVITY-PORE DEVICE ...................................................................................................................... 72 7 UTILIZING THE PORE-CAVITY-PORE DEVICE TO TRAP AND INVESTIGATE SINGLE NANO-SCALE OBJECTS IN FEMTO-LITER COMPARTMENTS: CONFINED DIFFUSION AND NARROW ESCAPE .................................................. 77 8 OUTLOOK ................................................................................................................................................. 89 APPENDIX .................................................................................................................................................. 95 A.1 TYPES OF NOISE IN RESISTIVE PULSE EXPERIMENTS UTILIZING A SOLID-STATE NANOPORE ........................ 95 A.2 DATA ANANLYSIS .............................................................................................................................. 98 A.3 MICROFLUIDIC CHAMBER ................................................................................................................... 99 A.4 CALCULATION OF THE AREA-WEIGHTED AVERAGE OF THE PYRAMID S CROSS-SECTIONAL SIDE LENGTH ........ 100 PUBLICATIONS ............................................................................................................................................ 101 DANKSAGUNG ............................................................................................................................................ 103 REFERENCES ............................................................................................................................................. 105
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discipline	Physik Chemie
edition	1. Aufl.
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physical	X, 114 S. Ill., graph. Darst. 21 cm
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spelling	Pedone, Daniel Claudio Verfasser (DE-588)1011232995 aut Nanopore analytics electro-optical studies on single molecules Daniel Claudio Pedone 1. Aufl. Garching Verein zur Förderung des Walter-Schottky-Inst. der Techn. Univ. München 2011 X, 114 S. Ill., graph. Darst. 21 cm txt rdacontent n rdamedia nc rdacarrier Selected topics of semiconductor physics and technology 126 Zugl.: München, Techn. Univ., Diss., 2011 Pore (DE-588)4352629-9 gnd rswk-swf Molekül (DE-588)4039972-2 gnd rswk-swf Halbleiter (DE-588)4022993-2 gnd rswk-swf Nanometerbereich (DE-588)4327473-0 gnd rswk-swf Chemischer Sensor (DE-588)4259288-4 gnd rswk-swf (DE-588)4113937-9 Hochschulschrift gnd-content Halbleiter (DE-588)4022993-2 s Pore (DE-588)4352629-9 s Nanometerbereich (DE-588)4327473-0 s Chemischer Sensor (DE-588)4259288-4 s Molekül (DE-588)4039972-2 s DE-604 Selected topics of semiconductor physics and technology 126 (DE-604)BV011499438 126 DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022531685&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Pedone, Daniel Claudio Nanopore analytics electro-optical studies on single molecules Selected topics of semiconductor physics and technology Pore (DE-588)4352629-9 gnd Molekül (DE-588)4039972-2 gnd Halbleiter (DE-588)4022993-2 gnd Nanometerbereich (DE-588)4327473-0 gnd Chemischer Sensor (DE-588)4259288-4 gnd
subject_GND	(DE-588)4352629-9 (DE-588)4039972-2 (DE-588)4022993-2 (DE-588)4327473-0 (DE-588)4259288-4 (DE-588)4113937-9
title	Nanopore analytics electro-optical studies on single molecules
title_auth	Nanopore analytics electro-optical studies on single molecules
title_exact_search	Nanopore analytics electro-optical studies on single molecules
title_full	Nanopore analytics electro-optical studies on single molecules Daniel Claudio Pedone
title_fullStr	Nanopore analytics electro-optical studies on single molecules Daniel Claudio Pedone
title_full_unstemmed	Nanopore analytics electro-optical studies on single molecules Daniel Claudio Pedone
title_short	Nanopore analytics
title_sort	nanopore analytics electro optical studies on single molecules
title_sub	electro-optical studies on single molecules
topic	Pore (DE-588)4352629-9 gnd Molekül (DE-588)4039972-2 gnd Halbleiter (DE-588)4022993-2 gnd Nanometerbereich (DE-588)4327473-0 gnd Chemischer Sensor (DE-588)4259288-4 gnd
topic_facet	Pore Molekül Halbleiter Nanometerbereich Chemischer Sensor Hochschulschrift
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022531685&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
volume_link	(DE-604)BV011499438
work_keys_str_mv	AT pedonedanielclaudio nanoporeanalyticselectroopticalstudiesonsinglemolecules

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