Peripheral neuropathies in clinical practice:
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Oxford [u.a.]
Oxford Univ. Press
2010
|
| Series: | Contemporary neurology series
76 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | XIII, 382 S. Ill., graph. Darst. |
| ISBN: | 9780195183269 |
Staff View
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| 264 | 1 | |a Oxford [u.a.] |b Oxford Univ. Press |c 2010 | |
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| adam_text | Titel: Peripheral neuropathies in clinical practice
Autor: Herskovitz, Steven
Jahr: 2010
Contents
1. BASIC CONCEPTS AND GLOSSARY OF COMMON CLINICAL
TERMS 3
DEFINITION OF THE PERIPHERAL NERVOUS SYSTEM (PNS) 3
RELATIONSHIPS FUNDAMENTAL TO AN UNDERSTANDING OF
DISEASE OF PERIPHERAL NERVE FIBERS 3
Neuron Cell Body and Axon ? Axon, Schwann Cell, and Myelin ? Axon and End Organ
Wallerian Degeneration and Axon Regeneration
GLOSSARY OF COMMON CLINICAL TERMS 7
2. ANATOMIC CLASSIFICATION OF PERIPHERAL NERVOUS
SYSTEM DISORDERS 9
SYMMETRIC GENERALIZED NEUROPATHIES (POLYNEUROPATHIES) 9
Distal Axonal Degeneration ? Segmental (Nonuniform) Myelinopathy ? Diffuse (Uniform)
Myelinopathy ? Neuronopathy (Ganglionopathy)
FOCAL (MONONEUROPATHY) AND MULTIFOCAL (MULTIPLE
MONONEUROPATHY) NEUROPATHIES 17
Ischemia ? Infiltration ? Physical Injuries
3. EVALUATION AND MANAGEMENT OF THE PATIENT WITH
PERIPHERAL NEUROPATHY 24
GENERAL PRINCIPLES AND THE ALGORITHMIC APPROACH 24
CHRONIC IDIOPATHIC AXONAL POLYNEUROPATHY
(CIAP)/SMALL-FIBER NEUROPATHY (SFN) 27
TREATMENT OF NEUROPATHIC PAIN 30
DIFFERENTIAL DIAGNOSES AND WORK-UPS FOR THE VARIED
NEUROPATHY PHENOTYPES 31
4 ELECTRODIAGNOSTIC, IMAGING, NERVE, AND SKIN BIOPSY
INVESTIGATIONS IN PERIPHERAL NERVE DISEASE 40
ELECTROMYOGRAPHY AND NERVE CONDUCTION STUDIES 40
Sensory Nerve Conduction Studies ? Motor Nerve Conduction Studies ? Late Responses
Blink Reflex Studies ? Needle Electromyography
VII
viii Contents
STUDIES OF AUTONOMIC FUNCTION 48
Quantitative Sudomotor Axon Reflex Test (QSART) ? Thermoregulatory- Sweat Test (TST) ?
Sympathetic Skin Response (SSR) ? Heart Rate Response to Deep Breathing ? Valsalva Maneuver
QUANTITATIVE SENSORY TESTING (QST) 49
DEVELOPING ELECTROPHYSIOLOGIC AND IMAGING TECHNIQUES 50
Motor Unit Number Estimation (MUNE) ? Electrical Impedance Myography (EIM) ?
High-Resolution Sonography of Peripheral Nerve ? Magnetic Resonance (MR)
Neurography ? Muscle MRI ? Positron Emission Tomography (PET)
NERVE BIOPSY 51
Indications ? Technical Considerations
SKIN BIOPSY 53
5. CASE PRESENTATIONS ILLUSTRATING THE DIAGNOSTIC
METHOD 56
CASE 1: PAINFUL SMALL-FIBER NEUROPATHY AND DYSAUTONOMIA 56
CASE 2: INSIDIOUS ONSET OF DISTAL WEAKNESS IN AN ADULT
WITH DEFORMED FEET 57
CASE 3: LOWER LIMB PARESTHESIAS IN A MIDDLE-AGED ADULT
WITH DIABETES 58
CASE 4: A MIDDLE-AGED WOMAN WITH MUSCLE TWITCHING
AND EPISODIC NUMBNESS 59
CASE 5: SIX DAYS OF CRANIAL NEUROPATHIES AND
HYPOREFLEXIA 60
CASE 6: TWO-MONTH ONSET OF SENSORY NEUROPATHY IN A
WOMAN WITH OVARIAN CARCINOMA 62
CASE 7: A 47-YEAR-OLD MAN WITH 10 YEARS OF PROGRESSIVE
BILATERAL HAND WEAKNESS 63
CASE 8: CHRONIC SENSORY LOSS AND UNSTEADY GAIT IN A
59-YEAR-OLD WOMAN 64
CASE 9: AN ELDERLY MAN WITH ACRAL PARESTHESIAS AND GAIT
UNSTEADINESS 65
CASE 10: FOOT DROP IN AN 81-YEAR-OLD WOMAN 66
CASE 11: A MIDDLE-AGED MAN WITH MULTIFOCAL PAIN, SENSORY
LOSS, AND WEAKNESS 68
CASE 12: FIVE-DAY ONSET OF DIFFUSE WEAKNESS 69
6 ACUTE IMMUNE-MEDIATED NEUROPATHIES 71
DEMYELINATING IMMUNE-MEDIATED NEUROPATHIES 71
Acute Inflammatory Demvelinating Polyradiculoneuropathy (AIDP) and Fisher
Syndrome (FS)
Contents
AXONAL IMMUNE-MEDIATED NEUROPATHIES 81
Acute Motor Axonal Neuropathy (AMAN) and Acute Motor and Sensory Axonal
Neuropathy (AMSAN)
NEURONOPATHIES 84
Sensory (Idiopathic, Sjogren Syndrome, Paraneoplastic) and Motor (Paraneoplastic)
Neuronopathies and Autoimmune Autonomic Ganglionopathy (AAG)
7. CHRONIC IMMUNE-MEDIATED NEUROPATHIES 96
CHRONIC INFLAMMATORY DEMYELINATING
POLYRADICULONEUROPATHY (CIDP) AND ITS VARIANTS 96
Introduction ? Clinical Features ? Laboratory- Studies ?
Pathology ? Pathogenesis ? Treatment ? Course and Prognosis
8. NEUROPATHIES ASSOCIATED WITH MONOCLONAL
GAMMOPATHIES AND CANCER 113
MULTIPLE MYELOMA, OSTEOSCLEROTIC MYELOMA, PRIMARY
SYSTEMIC AMYLOIDOSIS (AL AMYLOIDOSIS), WALDENSTROM
MACROGLOBULINEMIA, MONOCLONAL CAMMOPATHY OF
UNDETERMINED SIGNIFICANCE 113
Introduction ? Clinical Features ? Laboratory Studies ? Pathology ? Pathogenesis ?
Treatment, Course, and Prognosis
9. INFECTIOUS AND GRANULOMATOUS NEUROPATHIES 127
INTRODUCTION 127
HERPES ZOSTER/HERPES SIMPLEX 128
Clinical Features ? Pathology ? Treatment, Course, and Prognosis
LEPROSY 130
Clinical Features ? Laboratory Studies ? Nerve Biopsy/Pathology ?
Pathogenesis ? Treatment ? Course and Prognosis
SARCOIDOSIS 133
Clinical Features ? Laboratory Studies ? Nerve Biopsy/Pathology ? Pathogenesis ?
Treatment, Course, and Prognosis
LYME DISEASE 136
Clinical Features ? Laboratory Studies ? Nerve Biopsv/Pathologv ? Pathogenesis ?
Treatment. Course, and Prognosis
HUMAN IMMUNODEFICIENCY VIRUS (HIV)-RELATED PERIPHERAL
NEUROPATHIES 140
Clinical Features ? Laboratory Studies ? Nerve Biopsv/Pathologv ?
Pathogenesis ? Treatment ? Course and Prognosis
CRYOGLOBULINEMIA AND HEPATITIS C 147
Clinical Features ? Laboratory Studies ? Nerve Biopsy/ Pathology ?
Pathogenesis ? Treatment ? Course and Prognosis
x Contents
DIPHTHERIA 150
Clinical Features ? Laboratory Studies ? Pathology ? Treatment, Course,
and Prognosis
10. DIABETIC AND OTHER ENDOCRINE NEUROPATHIES 159
THE DIABETIC NEUROPATHIES 159
Introduction ? Distal Symmetric Sensorimotor/Autonomic Polyneuropathy (DSP/A) ? Autonomic
Neuropathy ? Proximal Multifocal Neuropathies (Diabetic Lumbosacral Radiculoplexus
Neuropathy and Thoracolumbar Truncal Neuropath)) ? Focal Limb Neuropathies
(Entrapment Neuropathies) ? Isolated Cranial Neuropathies ? Acute Painful Neuropathy
(Diabetic Neuropathic Cachexia) ? Diabetic Motor-Predominant Neuropathies ?
Treatment-Induced Neuropathy (Insulin Neuritis) ? Hyperglycemic Neuropathy
ACROMEGALIC NEUROPATHY 167
Introduction ? Mononeuropathv ? Distal Symmetric Polyneuropathy
HYPOTHYROID NEUROPATHY 168
Introduction ? Mononeuropathv ? Distal Symmetric Polyneuropathy
11. NEUROPATHIES ASSOCIATED WITH VITAMIN AND ESSENTIAL
MINERAL DEFICIENCIES AND MALABSORPTION 171
INTRODUCTION 171
VITAMIN B12 (COBALAMIN) DEFICIENCY 172
Clinical Features ? Laboratory Studies ? Nerve Biopsy/Pathology ? Pathogenesis ?
Treatment, Course, and Prognosis
VITAMIN B! (THIAMINE) DEFICIENCY 175
Clinical Features ? Laboratory- Studies ? Nerve Biopsy/Pathology ? Pathogenesis ?
Treatment, Course, and Prognosis
CELIAC DISEASE 177
Clinical Features ? Laboratory Studies ? Nerve Biopsy/Pathology ? Pathogenesis ?
Treatment, Course, and Prognosis
VITAMIN E (o-TOCOPHEROL) DEFICIENCY 179
Clinical Features ? Laboratory Studies ? Nerve Biopsy/Pathology ? Pathogenesis ?
Treatment, Course, and Prognosis
COPPER DEFICIENCY 181
Clinical Features ? Laboratory Studies ? Nerve Biopsy/Pathology- ? Pathogenesis ?
Treatment, Course, and Prognosis
OTHER: CUBAN EPIDEMIC OPTIC AND PERIPHERAL NEUROPATHY;
DEFICIENCIES: RIBOFLAVIN (VITAMIN B2), PYRIDOXINE (VITAMIN B6),
FOLATE, ZINC; BARIATRIC SURGERY 182
12. VASCULAR/ISCHEMIC NEUROPATHIES 188
VASCULITIC NEUROPATHIES 188
Introduction ? Clinical Features ? Laboratory Studies ? Pathology/Nerve Biopsy ?
Pathogenesis ? Treatment, Course, and Prognosis
Contents xi
NEUROPATHIES ASSOCIATED WITH PERIPHERAL ARTERIAL
OCCLUSIVE DISEASE 196
NEUROPATHIES ASSOCIATED WITH COMPARTMENT SYNDROMES 197
13. NEUROPATHIES ASSOCIATED WITH ORGAN FAILURE 201
PULMONARY FAILURE 201
HEPATIC FAILURE 202
RENAL FAILURE 202
Uremic Polyneuropathy ? Mononeuropathies ? Ischemic Monomelic Neuropathy
ORGAN TRANSPLANTATION 204
CRITICAL ILLNESS POLYNEUROPATHY 204
Differential Diagnosis
14 THE HEREDITARY NEUROPATHIES 211
HEREDITARY MOTOR AND SENSORY NEUROPATHIES
(HMSN)/CHARCOT-MARIE-TOOTH DISEASE (CMT) 212
Introduction ? Charcot-Marie-Tooth Disease, Type 1 (CMT1/HMSN I) ?
Hereditary Neuropathy with Liability to Pressure Palsy (HNPP) ? Charcot-Marie-
Tooth Disease, Type 2 (OMT2/HMSN II) ? Additional Autosomal Recessive Axonal
Neuropathies ? Dejerine-Sottas Disease and Congenital Hypomvelinating Neuropathy
(HMSN III) ? Charcot-Marie-Tooth Disease, Type 4 (CMT4. Autosomal Recessive CMT1,
ARCMT1, HMSN IV) ? Charcot-Marie-Tooth Disease, X-Linked (CMTX/HMSN X)
? Charcot-Marie-Tooth Disease, Dominant Intermediate (DI-CMT)
HEREDITARY SENSORY AND AUTONOMIC NEUROPATHIES (HSAN) 235
Introduction ? Clinical Features ? Laboratory Studies ? Pathology ? Pathophysiology ?
Treatment, Course, and Prognosis
DISTAL HEREDITARY MOTOR NEUROPATHIES/NEURONOPATHIES
(dHMN) 239
HEREDITARY ATAXIA WITFI NEUROPATHY 240
Autosomal Dominant ? Autosomal Recessive ? X-Linked
HEREDITARY SPASTIC PARAPLEGIA WITH NEUROPATHY
(HSP) 241
HEREDITARY BRACHIAL PLEXUS NEUROPATHY (HBPN)/
HEREDITARY NEURALGIC AMYOTROPHY (HNA) 242
Introduction ? Clinical Features ? Laboratory Studies ? Pathologv/Pathophvsiologv ?
Treatment, Course, and Prognosis
HEREDITARY PERIPHERAL NERVE CHANNELOPATHIES 243
Sodium Channelopathies ? Potassium Channelopathies
xii Contents
15 HEREDITARY METABOLIC/MULTISYSTEM DISORDERS WITH
NEUROPATHY 254
FAMILIAL AMYLOID POLYNEUROPATHIES 254
Introduction ? Clinical Features ? Laboratory Studies ? Pathology ? Pathophysiology ?
Treatment, Course, and Prognosis
DISORDERS OF LIPID METABOLISM 258
Lysosomal Disorders ? Peroxisomal Disorders ? Lipoprotein Deficiencies ?
Cerebrotendinous Xanthomatosis
PORPHYRIA 269
Introduction ? Clinical Features ? Laboratory Studies ? Pathology ? Pathophysiology ?
Treatment, Course, and Prognosis
DISORDERS OF DEFECTIVE DNA REPAIR 273
MITOCHONDRIAL DISORDERS 273
NEUROACANTHOCYTOSIS SYNDROMES 273
Chorea-Acanthocvtosis Syndrome ? McLeod Neuroaeanthocytosis Syndrome
NEUROFIBROMATOUS NEUROPATHY 277
Neurofibromatosis 1 ? Neurofibromatosis 2
GLYCOGEN STORAGE DISEASES 278
Adult Polvglucosan Body Disease
16. THE TOXIC NEURONOPATHY: PRINCIPLES OF GENERAL AND
PERIPHERAL NEUROTOXICOLOGY; PHARMACEUTICAL AGENTS 287
PRINCIPLES OF GENERAL NEUROTOXICOLOGY 287
PRINCIPLES OF PERIPHERAL NEUROTOXICOLOGY 289
Mononeuropathy ? Vasculitis/Fasciitis/Inflammation ?
Demyelinating Neuropathy ? Sensory Neuronopathy ? Toxic Channelopathy ?
Distal Axonopathv (Central-Peripheral Distal Axonopathv)
PERIPHERAL NEUROTOXICITY ASSOCIATED WITH
PHARMACEUTICAL AGENTS 290
Amiodarone ? Bortezomib ? Colchicine ? Dapsone ? Disulfiram ? Ethambutol ?
Ethanol ? Isoniazid ? Metronidazole ? Misonidazole ? Nitrous Oxide ?
Nucleoside Analogues ? Phenvtoin ? Platinum (Cisplatin and Oxaliplatin) ?
Pyridoxine ? Suramin ? Tacrolimus ? Taxanes ? Thalidomide ? Vinca Alkaloids
17. THE TOXIC NEUROPATHIES: INDUSTRIAL, OCCUPATIONAL,
AND ENVIRONMENTAL AGENTS 301
PERIPHERAL NEUROTOXICITY ASSOCIATED WITH INDUSTRIAL,
OCCUPATIONAL, AND ENVIRONMENTAL AGENTS 301
Arsenic (Inorganic) ? Ethylene Oxide ? Hexacarbons (n-Hexane) ? Lead ? Methyl
Bromide ? Organophosphates ? Thallium
Contents xiii
18. FOCAL NEUROPATHIES: NERVE INJURIES, ENTRAPMENTS, AND
OTHER MONONEUROPATHIES 311
NERVE INJURIES 311
Anatomy and Pathophysiology of Nerve Injuries ? Clinical Classification of Nerve
Injuries ? Electrodiagnostic Features of Nerve Injuries ? Nerve Regeneration
and Repair
FOCAL NEUROPATHIES: THE UPPER EXTREMITY 313
Median Nerve ? Ulnar Nerve ? Radial Nerve ? Other Upper Extremity
Mononeuropathies
FOCAL NEUROPATHIES: THE LOWER EXTREMITY 330
Sciatic Nerve ? Peroneal Nerve ? Tibial Nerve ? Femoral Nerve ? Lateral
Femoral Cutaneous Nerve ? Other Lower Extremity Mononeuropathies
FOCAL NEUROPATHIES: CRANIAL NEUROPATHIES 340
Idiopathic Facial Nerve Paralysis (Bell s Palsy)
19. PLEXOPATHIES 346
BRACHIAL PLEXOPATHY 346
Anatomv ? Etiologv
LUMBOSACRAL PLEXOPATHY 355
Anatomv ? Etiology
20 DISORDERS OF PERIPHERAL NERVE HYPEREXCITABILITY 362
GENERALIZED DISORDERS 362
Neuromvotonia ? Cramps ? Fasciculations ? Tetany
LOCALIZED DISORDERS 367
Facial Mvokvmia ? Localized, Focal Mvokvmia ? Hemifacial Spasm ?
Hemimastieatorv Spasm ? Hvpothenar Dimpling
INDEX 371
|
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| id | DE-604.BV036104008 |
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| indexdate | 2024-07-09T22:11:41Z |
| institution | BVB |
| isbn | 9780195183269 |
| language | English |
| lccn | 2009014128 |
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| series | Contemporary neurology series |
| series2 | Contemporary neurology series |
| spelling | Herskovitz, Steven Verfasser aut Peripheral neuropathies in clinical practice Steven Herskovitz ; Stephen N. Scelsa ; Herbert H. Schaumburg Oxford [u.a.] Oxford Univ. Press 2010 XIII, 382 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Contemporary neurology series 76 Includes bibliographical references and index Nerves, Peripheral Diseases Peripheral Nervous System Diseases Peripheres Nervensystem (DE-588)4173794-5 gnd rswk-swf Neuralgie (DE-588)4198767-6 gnd rswk-swf Peripheres Nervensystem (DE-588)4173794-5 s Neuralgie (DE-588)4198767-6 s DE-604 Scelsa, Stephen N. Verfasser aut Schaumburg, Herbert H. 1932- Verfasser (DE-588)143356380 aut Contemporary neurology series 76 (DE-604)BV000898796 76 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018994308&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Herskovitz, Steven Scelsa, Stephen N. Schaumburg, Herbert H. 1932- Peripheral neuropathies in clinical practice Contemporary neurology series Nerves, Peripheral Diseases Peripheral Nervous System Diseases Peripheres Nervensystem (DE-588)4173794-5 gnd Neuralgie (DE-588)4198767-6 gnd |
| subject_GND | (DE-588)4173794-5 (DE-588)4198767-6 |
| title | Peripheral neuropathies in clinical practice |
| title_auth | Peripheral neuropathies in clinical practice |
| title_exact_search | Peripheral neuropathies in clinical practice |
| title_full | Peripheral neuropathies in clinical practice Steven Herskovitz ; Stephen N. Scelsa ; Herbert H. Schaumburg |
| title_fullStr | Peripheral neuropathies in clinical practice Steven Herskovitz ; Stephen N. Scelsa ; Herbert H. Schaumburg |
| title_full_unstemmed | Peripheral neuropathies in clinical practice Steven Herskovitz ; Stephen N. Scelsa ; Herbert H. Schaumburg |
| title_short | Peripheral neuropathies in clinical practice |
| title_sort | peripheral neuropathies in clinical practice |
| topic | Nerves, Peripheral Diseases Peripheral Nervous System Diseases Peripheres Nervensystem (DE-588)4173794-5 gnd Neuralgie (DE-588)4198767-6 gnd |
| topic_facet | Nerves, Peripheral Diseases Peripheral Nervous System Diseases Peripheres Nervensystem Neuralgie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018994308&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000898796 |
| work_keys_str_mv | AT herskovitzsteven peripheralneuropathiesinclinicalpractice AT scelsastephenn peripheralneuropathiesinclinicalpractice AT schaumburgherberth peripheralneuropathiesinclinicalpractice |