Verfügbarkeit: Complement in autoimmunity

Complement in autoimmunity:

Complement protein expression and activation control central aspects of the normal B cell response. Imbalances in these processes invariably lead to autoimmune disease. Complement activation causes tissue damage in a number of ways and may by itself lead to autoimmune disease. Although the use of co...

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Weitere Verfasser:	Tsokos, George C. (HerausgeberIn)
Format:	Elektronisch E-Book
Sprache:	English
Veröffentlicht:	Basel Karger 2004
Schriftenreihe:	Current directions in autoimmunity Vol. 7
Schlagworte:	Immunology Biochemistry Cell Biology Genetics Hematology Infectious Diseases Nephrology Rheumatology Komplement > Immunologie Pathogenese Autoaggressionskrankheit Aufsatzsammlung
Online-Zugang:	BFB01 BSB01 BTW01 EUV01 FAN01 FAW01 FFW01 FHI01 FHM01 FHN01 FHR01 FKE01 FNU01 FWS01 FWS02 GEM01 LCO01 SAB01 SAM01 SBG01 SBR01 SND01 TUM01 UBA01 UBG01 UBM01 UBR01 UBT01 UBW01 UER01 UPA01 Volltext
Zusammenfassung:	Complement protein expression and activation control central aspects of the normal B cell response. Imbalances in these processes invariably lead to autoimmune disease. Complement activation causes tissue damage in a number of ways and may by itself lead to autoimmune disease. Although the use of complement activation inhibitors in the treatment of complement-mediated tissue injury and disease is largely in pre-clinical trials, the expectations that they will be of significant clinical value are high. This volume contains a series of review articles that address the role of complement in the pathogenesis of autoimmune disease and the ensuing tissue damage. Topics include structural and functional aspects of the CD19/CD21/CD81 complex, role of the complement system in the expression of systemic lupus erythematosus (SLE) and antiphospholipid antibody syndrome. Also featured is the role of complement activation in ischemia/reperfusion and autoimmune disease injury. Finally, in-depth reviews about complement activation in the development of glomerulonephritis in autoimmune disease and the function of membrane-bound complement regulatory proteins in autoimmunity are presented.Students as well as basic and clinical researchers in immunology who wish to understand the role of complement in the pathogenesis of autoimmune disease will value this comprehensive and up-to-date publication
Beschreibung:	a vital approach to a key component of the innate immune system
Beschreibung:	1 Online-Ressource (VI, 205 Seiten) Illustrationen, Diagramme
ISBN:	9783318010244

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genre	(DE-588)4143413-4 Aufsatzsammlung gnd-content
genre_facet	Aufsatzsammlung
id	DE-604.BV036069075
illustrated	Not Illustrated
indexdate	2024-08-01T11:41:30Z
institution	BVB
isbn	9783318010244
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-018960378
oclc_num	837652316
open_access_boolean
owner	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046
owner_facet	DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046
physical	1 Online-Ressource (VI, 205 Seiten) Illustrationen, Diagramme
psigel	ZDB-1-KEB
publishDate	2004
publishDateSearch	2004
publishDateSort	2004
publisher	Karger
record_format	marc
series	Current directions in autoimmunity
series2	Current directions in autoimmunity
spellingShingle	Complement in autoimmunity Current directions in autoimmunity Immunology Biochemistry Cell Biology Genetics Hematology Infectious Diseases Nephrology Rheumatology Komplement Immunologie (DE-588)4120589-3 gnd Pathogenese (DE-588)4115512-9 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd
subject_GND	(DE-588)4120589-3 (DE-588)4115512-9 (DE-588)4003935-3 (DE-588)4143413-4
title	Complement in autoimmunity
title_auth	Complement in autoimmunity
title_exact_search	Complement in autoimmunity
title_full	Complement in autoimmunity volume editor: George C. Tsokos
title_fullStr	Complement in autoimmunity volume editor: George C. Tsokos
title_full_unstemmed	Complement in autoimmunity volume editor: George C. Tsokos
title_short	Complement in autoimmunity
title_sort	complement in autoimmunity
topic	Immunology Biochemistry Cell Biology Genetics Hematology Infectious Diseases Nephrology Rheumatology Komplement Immunologie (DE-588)4120589-3 gnd Pathogenese (DE-588)4115512-9 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd
topic_facet	Immunology Biochemistry Cell Biology Genetics Hematology Infectious Diseases Nephrology Rheumatology Komplement Immunologie Pathogenese Autoaggressionskrankheit Aufsatzsammlung
url	https://karger.com/books/book/2460
volume_link	(DE-604)BV039142746
work_keys_str_mv	AT tsokosgeorgec complementinautoimmunity

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