Complement in autoimmunity:
Complement protein expression and activation control central aspects of the normal B cell response. Imbalances in these processes invariably lead to autoimmune disease. Complement activation causes tissue damage in a number of ways and may by itself lead to autoimmune disease. Although the use of co...
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| Format: | Electronic eBook |
| Language: | English |
| Published: |
Basel
Karger
2004
|
| Series: | Current directions in autoimmunity
Vol. 7 |
| Subjects: | |
| Online Access: | DE-522 DE-12 DE-526 DE-521 DE-1102 DE-1046 DE-1028 DE-573 DE-M347 DE-92 DE-898 DE-859 DE-1049 DE-863 DE-862 DE-M382 DE-70 DE-128 DE-54 DE-22 DE-155 DE-150 DE-91 DE-384 DE-473 DE-19 DE-355 DE-703 DE-20 DE-706 DE-29 DE-739 Volltext |
| Summary: | Complement protein expression and activation control central aspects of the normal B cell response. Imbalances in these processes invariably lead to autoimmune disease. Complement activation causes tissue damage in a number of ways and may by itself lead to autoimmune disease. Although the use of complement activation inhibitors in the treatment of complement-mediated tissue injury and disease is largely in pre-clinical trials, the expectations that they will be of significant clinical value are high. This volume contains a series of review articles that address the role of complement in the pathogenesis of autoimmune disease and the ensuing tissue damage. Topics include structural and functional aspects of the CD19/CD21/CD81 complex, role of the complement system in the expression of systemic lupus erythematosus (SLE) and antiphospholipid antibody syndrome. Also featured is the role of complement activation in ischemia/reperfusion and autoimmune disease injury. Finally, in-depth reviews about complement activation in the development of glomerulonephritis in autoimmune disease and the function of membrane-bound complement regulatory proteins in autoimmunity are presented.Students as well as basic and clinical researchers in immunology who wish to understand the role of complement in the pathogenesis of autoimmune disease will value this comprehensive and up-to-date publication |
| Item Description: | a vital approach to a key component of the innate immune system |
| Physical Description: | 1 Online-Ressource (VI, 205 Seiten) Illustrationen, Diagramme |
| ISBN: | 9783318010244 |
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| genre | (DE-588)4143413-4 Aufsatzsammlung gnd-content |
| genre_facet | Aufsatzsammlung |
| id | DE-604.BV036069075 |
| illustrated | Illustrated |
| indexdate | 2025-03-04T04:01:17Z |
| institution | BVB |
| isbn | 9783318010244 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018960378 |
| oclc_num | 837652316 |
| open_access_boolean | |
| owner | DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046 DE-706 |
| owner_facet | DE-384 DE-473 DE-BY-UBG DE-703 DE-29 DE-19 DE-BY-UBM DE-91 DE-BY-TUM DE-739 DE-355 DE-BY-UBR DE-20 DE-1102 DE-1028 DE-573 DE-859 DE-M347 DE-1049 DE-92 DE-898 DE-BY-UBR DE-863 DE-BY-FWS DE-862 DE-BY-FWS DE-128 DE-54 DE-22 DE-BY-UBG DE-150 DE-155 DE-BY-UBR DE-521 DE-522 DE-526 DE-12 DE-11 DE-83 DE-M382 DE-70 DE-578 DE-1046 DE-706 |
| physical | 1 Online-Ressource (VI, 205 Seiten) Illustrationen, Diagramme |
| psigel | ZDB-1-KEB |
| publishDate | 2004 |
| publishDateSearch | 2004 |
| publishDateSort | 2004 |
| publisher | Karger |
| record_format | marc |
| series | Current directions in autoimmunity |
| series2 | Current directions in autoimmunity |
| spellingShingle | Complement in autoimmunity Current directions in autoimmunity Immunology Biochemistry Cell Biology Genetics Hematology Infectious Diseases Nephrology Rheumatology Komplement Immunologie (DE-588)4120589-3 gnd Pathogenese (DE-588)4115512-9 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd |
| subject_GND | (DE-588)4120589-3 (DE-588)4115512-9 (DE-588)4003935-3 (DE-588)4143413-4 |
| title | Complement in autoimmunity |
| title_auth | Complement in autoimmunity |
| title_exact_search | Complement in autoimmunity |
| title_full | Complement in autoimmunity volume editor: George C. Tsokos |
| title_fullStr | Complement in autoimmunity volume editor: George C. Tsokos |
| title_full_unstemmed | Complement in autoimmunity volume editor: George C. Tsokos |
| title_short | Complement in autoimmunity |
| title_sort | complement in autoimmunity |
| topic | Immunology Biochemistry Cell Biology Genetics Hematology Infectious Diseases Nephrology Rheumatology Komplement Immunologie (DE-588)4120589-3 gnd Pathogenese (DE-588)4115512-9 gnd Autoaggressionskrankheit (DE-588)4003935-3 gnd |
| topic_facet | Immunology Biochemistry Cell Biology Genetics Hematology Infectious Diseases Nephrology Rheumatology Komplement Immunologie Pathogenese Autoaggressionskrankheit Aufsatzsammlung |
| url | https://karger.com/books/book/2460 |
| volume_link | (DE-604)BV039142746 |
| work_keys_str_mv | AT tsokosgeorgec complementinautoimmunity |