Liposomes: G
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Amsterdam [u.a.]
Acad. Press
2009
|
| Edition: | 1. ed. |
| Series: | Methods in enzymology
465 |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XLVII, 399 S., [8] Bl. Ill., graph. Darst. |
| ISBN: | 9780123813794 |
Staff View
MARC
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| 245 | 1 | 0 | |a Liposomes |n G |c ed. by Nejat Düzgüneş |
| 250 | |a 1. ed. | ||
| 264 | 1 | |a Amsterdam [u.a.] |b Acad. Press |c 2009 | |
| 300 | |a XLVII, 399 S., [8] Bl. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
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| 490 | 1 | |a Methods in enzymology |v 465 | |
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Record in the Search Index
| _version_ | 1804140897613381632 |
|---|---|
| adam_text | Contents
Contributors
xiii
Preface
xix
Volumes in Series
xxi
Section I. Advances in
Liposome
Formation and
Characterization
1
1.
Spontaneously Formed Unilamellar Vesicles
3
Mu-Ping Nieh, Norbert
Kučerka,
and John Katsaras
1.
Introduction
4
2.
Preparation of Spontaneously Forming ULVs
5
3.
Characterization of ULVs
6
4.
ULV
Stability
7
5.
Parameters Affecting ULVs
б
6.
Mechanism of
ULV
Formation
12
7.
Encapsulation and Controlled Release Mechanism of
Spontaneously Formed ULVs
13
8.
Application
16
9.
Concluding Remarks
16
Acknowledgement
17
References
17
2.
Use of Acoustic Sensors to Probe the Mechanical
Properties of
Liposomes
21
Kathryn Melzak, Achilleas Tsortos, and Electra Gizeli
1.
Introduction
22
2.
Acoustic Measurements
25
3.
Experimental Procedures
29
4.
Change in APh and
M
for Adsorbed Vesicles as a Function of
Cholesterol Content
34
5.
Comparison of the Results to Various Model Systems
36
6.
Can the Response Be Explained in Terms of Variable
Slip at the Surface?
38
7.
Displacements Associated with the
Liposomes
38
Contents
8.
Concluding Remarks
39
Acknowledgments
39
References
39
3.
Liposome
Characterization by Quartz Crystal
Microbalance
Measurements and Atomic Force Microscopy
43
Patrick Vermette
1.
Introduction
44
2.
Liposomes
Assessed by AFM
46
3.
QCM Measurements of Intact
Liposomes
57
4.
Surface-Bound
Liposomes
¡η
Perspective and General Conclusions
65
References
67
4.
Mixing Solutions in InkJet Formed Vesicles
75
Thomas H. Li, Jeanne
С
Stachowiak, and Daniel A. Fletcher
1.
Introduction
76
2.
Unilamellar Vesicle Formation by Microfluidic Encapsulation
79
3.
Determination of Encapsulation Fraction within Vesicles
82
4.
Concluding Remarks
92
References
93
5.
Recombinant
Proteoliposomes Prepared Using Baculovirus
Expression Systems
95
Kanta
Tsumoto and Tetsuro Yoshimura
1.
Introduction
96
2.
Principles of
Recombinant Proteoliposome
Preparation
96
3.
Construction of
Recombinant
AcNPVs
98
4.
Expression of
Recombinant
Proteins on BV Envelopes
99
5.
Preparation of Proteoliposomes by Fusion of BVs with
Liposomes
101
6.
Concluding Remarks
107
References
108
6.
Block
Liposomes:
Vesicles of Charged Lipids with Distinctly
Shaped Nanoscale Sphere-, Pear-, Tube-, or Rod-Segments 111
Alexandra
Židovska,
Kai
К.
Ewert, Joel Quispe, Bridget Carragher,
Clinton S. Potter, and Cyrus R. Safinya
1.
Introduction
112
2.
Liposome
Preparation
115
3.
Microscopy
115
Contents
vii
4. Design
and Synthesis of MVLBG2
116
5.
Phase Behavior of MVLBG2/D0PC
Lipid
Mixtures
118
6.
Concluding Remarks
126
Acknowledgments
126
References
127
7.
Microfluidic Methods for Production of
Liposomes
129
Bo Yu, Robert J. Lee, and L. James Lee
1.
Introduction
130
2.
Conventional Technologies for Production of
Liposomes
131
3.
Microfluidic Technologies for Synthesis of Nanoparticles
132
4.
Microfluidic Technologies for Production of
Liposomes
133
5.
Concluding Remarks
138
Acknowledgments
139
References
139
8.
Constructing Size Distributions of
Liposomes
from Single-Object
Fluorescence Measurements
143
Christina Lohr, Andreas H. Kunding, Vikram K. Bhatia,
and Dimitrios Stamou
1.
Introduction
144
2.
How Particle Size can be Obtained from Intensity Distributions
147
3.
Vesicle Preparation and Immobilization
147
4.
Image Acquisition
149
5.
Image Processing
151
6.
Intensity and Size Distributions
155
7.
Multilamellarity Assay
155
8.
Measuring Membrane-Curvature Selective Protein Binding
158
9.
Concluding Remarks
158
References
159
9.
Giant Unilamellar Vesicle Electroformation: From
Lipid
Mixtures to Native Membranes Under Physiological Conditions
161
Philippe
Méléard, Luis
A. Bagatolli, and
Tanja Pott
1.
Introduction
162
2.
General GUV Electroformation Protocol
164
3.
Methods for GUV Electroformation from
Lipid
Mixtures,
Liposomes,
and Native Membranes
167
4.
Concluding Remarks
173
References
174
v¡¡¡
Contents
Section II.
Liposomes
in Therapeutics
177
10.
Liposomal Boron Delivery for Neutron Capture Therapy
179
Hiroyuki Nakamura
1.
Introduction 180
2.
Boron-Encapsulation Approach
183
3.
Boron Lipid-Liposome Approach
186
4.
n/t/o-Carborane
Lipid
Liposomes
187
5.
Transferrin-Conjugated mcto-Carborane
Lipid
Liposomes
189
6.
doso-Dodecaborate
Lipid
Liposomes
193
7.
Concluding Remarks
203
References
203
11.
Production of
Recombinant Proteoliposomes
for
Therapeutic Uses
209
Lavinia Liguori and Jean Luc Lenormand
1.
Introduction
210
2.
Expression of
Bak
Protein Using a Bacterial Cell-Free
Expression System
213
3.
Scale-Up Production of
Bak
Proteoliposomes
215
4.
Bak
Proteoliposome Production
216
5.
Liposome
Preparation
216
6.
Proteoliposome Purification
217
7.
Analysis of the Purified
Bak
Proteoliposomes
217
8.
Transmission Electron Microscopy
218
9.
Apoptosis Induction in Cancer Cell Lines: Caspase
9
Activation
220
10.
Concluding Remarks
221
Acknowledgments
222
References
222
12.
Liposome-Mediated Therapy of
Neuroblastoma
225
Daniela
Di
Paolo, Monica
Loi,
Fabio Pastorino, Chiara Brignole,
Danilo
Marimpietri, Pamela
Becherini,
Irene
Caffa, Alessia Zorzolì,
Renato Longhi,
Cristina
Gagliani, Carlo Tacchetti, Angelo Corti,
Theresa
M.
Allen, Mirčo Ponzoni, and
Gabriella Pagnan
1.
Introduction
226
2.
Materials
227
3.
Untargeted
Liposomes
Entrapping Doxorubicin
227
4.
Tumor-Targeted Liposomal Chemotherapy
228
5.
Vascular-Targeted Liposomal Chemotherapy
232
6.
Liposomes
Entrapping Fenretinide (HPR)
236
Contents
¡χ
7. Antisense Oligonucleotide-Entrapped
Liposomes
237
8.
Gold-Containing
Liposomes
241
Acknowledgments
243
References
243
13.
Tumor-Specific Liposomal Drug Release Mediated
by Liposomase
251
Ian Cheong and Shibin Zhou
1.
Introduction
252
2.
Tumor Models
254
3.
Generation of
С
novyi Spores and
C novyi-NT
255
4.
Preparation of Liposomal Formulations
256
5.
Combination Therapy with
С
novyi-NT Spores and
Liposomes
259
6.
Purification and Identification of Liposomase
259
7.
Conclusion and Future Perspectives
263
References
263
14.
Targeted Lipoplexes for siRNA Delivery
267
Ana Cardoso, Sara Trabulo,
João
Nuno
Moreira,
Nejat Düzgünes,
and Maria C. Pedroso
de
Lima
1.
Introduction
268
2.
Liposome
and Complex Preparation
270
3.
Physicochemical Characterization of the Complexes
271
4.
Assessment of siRNA Protection
273
5.
Assessment of Lipoplex Internalization and Biological
Activity In Vitro
276
6.
Cell Viability Studies
283
7.
Concluding Remarks
285
References
286
15.
Mucosal Delivery of Liposome-Chitosan
Nanoparticle Complexes
289
Edison L. S.
Carvalho, Ana Grenha,
Carmen
Remuñán-López,
Maria
José Alonso,
and
Begoña Seijo
1.
Introduction
290
2.
Preparation of Liposome-Chitosan Nanopartide
(L/CS-NP) Complexes
292
3.
Characterization of (L/CS-NP) Complexes
298
4.
Results
304
5.
Conclusions and Prospects
309
Acknowledgment
310
References
310
x
Contents
16. Antiangiogenic Photodynamic
Therapy with Targeted
Liposomes
313
Naoto Oku and Takayuki
Ishîi
1.
Introduction
314
2. PDTwithPEG-CoatedüposomalBPD-MA 316
3.
PDT
with Polycation-Coated Liposomal BPD-MA
318
4.
PDT
with Tumor Angiogenic Vessel-Targeted Liposomal BPD-MA
324
5.
Usefulness of Antiangiogenic
PDT
with Neovessel-Targeted
Liposomes
327
6.
Concluding Remarks
329
References
329
17.
Controlling the In Vivo Activity of Wnt
Liposomes
331
L.
Zhao,
S. M. Rooker,
N.
Morrell, P. Leucht,
D. Simanovskii, and j. A. Helms
1.
Introduction
332
2.
Materials, Methods, and Results
334
3.
Concluding Remarks
343
References
345
18.
Convection-Enhanced Delivery of
Liposomes
to Primate Brain
349
Michal
T.
Krauze, John Forsayeth,
Dali
Yin, and
Kryštof
S. Bankiewicz
1.
Introduction
350
2.
Liposome
Preparation
351
3.
Quantification of Liposome-Entrapped Gadoteridol
by Magnetic Resonance Imaging
352
4.
Experimental Subjects
353
5.
Infusion Catheter Design and Infusion Procedure
353
6.
Distribution of
Liposomes
Within Anatomic Structures
of the Primate Brain
357
7.
Volumetric Calculations of Liposomal Distribution in Primate CNS
359
8.
Future and Outlook of
CED
to Brain
359
Acknowledgment
360
References
360
19.
Hemoglobin-Vesicles as an Artificial Oxygen Carrier
363
Hiromi Sakai, Keitaro Sou, and Eishun Tsuchida
1.
Introduction: Encapsulated Hemoglobin as an
Artificial Oxygen Carrier
364
2.
Encapsulation of Concentrated Hb in
Liposomes
366
3.
Source of Hb and Its Purification
368
4.
Regulation of Oxygen Affinity
371
5.
Structural Stabilization of Liposome-Encapsulated Hb
372
Contents xi
6.
Blood Compatibility of
LEH
and HbV
374
7.
Regulation of Osmotic Pressure and Suspension Rheology to
Mimic and Overwhelm the Function of Blood
375
8.
Concluding Remarks
377
References
378
Author Index
385
Subject Index
393
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| id | DE-604.BV035912161 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T22:07:17Z |
| institution | BVB |
| isbn | 9780123813794 |
| language | English |
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| physical | XLVII, 399 S., [8] Bl. Ill., graph. Darst. |
| publishDate | 2009 |
| publishDateSearch | 2009 |
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| publisher | Acad. Press |
| record_format | marc |
| series | Methods in enzymology |
| series2 | Methods in enzymology Methodes in enzymology |
| spelling | Liposomes G ed. by Nejat Düzgüneş 1. ed. Amsterdam [u.a.] Acad. Press 2009 XLVII, 399 S., [8] Bl. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in enzymology 465 Methodes in enzymology ... Düzgüneş, Nejat Sonstige (DE-588)129612227 oth (DE-604)BV017710869 7 Methods in enzymology 465 (DE-604)BV000000938 465 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018769425&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Liposomes Methods in enzymology |
| title | Liposomes |
| title_auth | Liposomes |
| title_exact_search | Liposomes |
| title_full | Liposomes G ed. by Nejat Düzgüneş |
| title_fullStr | Liposomes G ed. by Nejat Düzgüneş |
| title_full_unstemmed | Liposomes G ed. by Nejat Düzgüneş |
| title_short | Liposomes |
| title_sort | liposomes |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018769425&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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