Adverse drug reactions:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Heidelberg [u.a.]
Springer
2010
|
| Series: | Handbook of experimental pharmacology
196 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | X, 556 S. Ill., graph. Darst. |
| ISBN: | 9783642006623 9783642006630 |
Staff View
MARC
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Record in the Search Index
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|---|---|
| adam_text | Contents
Part I Target Organ
Toxicity
1
Drug-Induced Liver Injury
................................................ 3
Michael Holt and Cynthia Ju
2
Drug Hypersensitivity Reactions Involving Skin
........................ 29
Oliver
Hausmann, Benno
Schnyder, and Werner J. Pichler
3
Adverse Drug Reactions Affecting Blood Cells
......................... 57
Richard H. Aster
4
Molecular Mechanisms of Adverse Drug Reactions
in Cardiac Tissue
.......................................................... 77
Reza Tabrizchi
5
Mechanisms of Drug-Induced Nephrotoxicity
.........................
Ill
Thomas D. Nolin and Jonathan Himmelfarb
6
Receptor- and Reactive Intermediate-Mediated Mechanisms
of Teratogenesis
.......................................................... 131
Peter G. Wells, Crystal J.J. Lee, Gordon P. McCallum,
Julia Perstin, and Patricia A. Harper
Part II Mediators/Biochemical Pathways
7
Role of Reactive Metabolites in Drug-Induced Hepatotoxicity
...... 165
Srivastava
Α.,
Maggs J.L.,
Antoine
DJ.,
Williams D.P.,
Smith D.A., and Park B.K.
8
The Role of Cytokines in the Mechanism of Adverse
Drug Reactions
........................................................... 195
Mary Jane Masson, Lindsay A. Collins, and Lance R.
Pohl
viii Contents
9
The
Keapl-Nrfž
Cellular Defense Pathway: Mechanisms
of Regulation and Role in Protection Against
Drug-Induced
Toxicity
.................................................. 233
Ian M.
Coppie,
Christopher E.
Goldring, Neil R.
Kitteringham,
and B. Kevin Park
10
Signal Transduction Pathways Involved in Drug-Induced
Liver Injury
.............................................................. 267
Deride
Han,
Mie
Shinohara, Maria D. Ybanez, Behnam Saberi,
and Neil Kaplowitz
11
Mitochondria! Involvement in Drug-Induced Liver Injury
.......... 311
Dominique Pessayre, Abdellah Mansouri, Alain Berson,
and Bernard Fromenty
Part III Examples/Models
12
Mechanisms of Acetaminophen-Induced Liver Necrosis
............. 369
Jack A. Hinson, Dean W. Roberts, and Laura P. James
13
Drug-Induced Liver Injury in Humans: The Case
of Ximelagatran
.......................................................... 407
M. Keisu and
T. B. Andersson
14
Troglitazone
.............................................................. 419
Tsuyoshi Yokoi
15
Nevirapine Hypersensitivity
............................................ 437
M. Popovic, J.M. Shenton, J. Chen,
A. Baban,
T.
Tharmanathan,
В.
Mannargudi,
D.
AbduUa, and J.P. Uetrecht
16
Mechanisms of Adverse Drug Reactions to Biologies
................. 453
Janet B. Clarke
Part IV Risk Factors/Screening Drug Candidates
17
Pharmacogenetics of Idiosyncratic Adverse Drug Reactions
........ 477
Munir
Pirmohamed
18
The Danger Hypothesis Applied to Idiosyncratic Drug Reactions
.... 493
Jinze Li and Jack P. Uetrecht
19
Approaches for Minimizing Metabolic Activation
of New Drug Candidates in Drug Discovery
.......................... 511
Sanjeev Kumar, Kaushik
Mitra,
Kelem Kassahun,
and Thomas A. Baillie
Index
........................................................................... 545
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| series | Handbook of experimental pharmacology |
| series2 | Handbook of experimental pharmacology |
| spelling | Adverse drug reactions Jack Utrecht, ed. Heidelberg [u.a.] Springer 2010 X, 556 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Handbook of experimental pharmacology 196 pharmacology cabt drugs cabt adverse effects cabt Drug Toxicity Drugs Side effects Pharmaceutical Preparations adverse effects Arzneimittelnebenwirkung (DE-588)4003134-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Arzneimittelnebenwirkung (DE-588)4003134-2 s DE-604 Uetrecht, Jack P. Sonstige (DE-588)139950524 oth Handbook of experimental pharmacology 196 (DE-604)BV002390716 196 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018721030&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Adverse drug reactions Handbook of experimental pharmacology pharmacology cabt drugs cabt adverse effects cabt Drug Toxicity Drugs Side effects Pharmaceutical Preparations adverse effects Arzneimittelnebenwirkung (DE-588)4003134-2 gnd |
| subject_GND | (DE-588)4003134-2 (DE-588)4143413-4 |
| title | Adverse drug reactions |
| title_auth | Adverse drug reactions |
| title_exact_search | Adverse drug reactions |
| title_full | Adverse drug reactions Jack Utrecht, ed. |
| title_fullStr | Adverse drug reactions Jack Utrecht, ed. |
| title_full_unstemmed | Adverse drug reactions Jack Utrecht, ed. |
| title_short | Adverse drug reactions |
| title_sort | adverse drug reactions |
| topic | pharmacology cabt drugs cabt adverse effects cabt Drug Toxicity Drugs Side effects Pharmaceutical Preparations adverse effects Arzneimittelnebenwirkung (DE-588)4003134-2 gnd |
| topic_facet | pharmacology drugs adverse effects Drug Toxicity Drugs Side effects Pharmaceutical Preparations adverse effects Arzneimittelnebenwirkung Aufsatzsammlung |
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