Dynamic combinatorial chemistry:
Saved in:
| Other Authors: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Weinheim
Wiley-VCH
2010
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | X, 201 S. |
| ISBN: | 9783527321223 |
Staff View
MARC
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Record in the Search Index
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| adam_text | CONTENTS LIST OF CONTRIBUTORS IX 1 HISTORY AND PRINCIPLES OF DYNAMIC
COMBINATORIAL CHEMISTRY 1 SOPHIE R. BEEREN AND JEREMY K.M. SANDERS 1.1
INTRODUCTION 1 1.2 HISTORY 3 1.2.1 THERMODYNAMICALLY CONTROLLED
TEMPLATED SYNTHESIS 3 1.2.2 EARLY DCLS 5 1.3 EXERCISING CONTROL OVER A
DCL TO INFLUENCE SPECIES DISTRIBUTION 7 1.3.1 SELECTION THROUGH
MOLECULAR RECOGNITION OF AN EXTERNAL TEMPLATE 7 1.3.2 SELECTION THROUGH
SELF-TEMPLATING 7 1.3.3 SELECTION DIRECTED BY EXTERNAL PHYSICAL STIMULI
9 1.3.4 SELECTION THROUGH A STABILIZING PHASE CHANGE 10 1.4 DESIGNING A
DYNAMIC COMBINATORIAL SYSTEM 12 1.4.1 BUILDING BLOCK DESIGN 13 1.4.2
EXCHANGE REACTIONS 14 1.4.3 EXCHANGE REACTIONS CURRENTLY IN USE 15
1.4.3.1 REVERSIBLE BENZYLIC NUDEOPHILIC SUBSTITUTION 15 1.4.3.2 NITRONE
EXCHANGE 18 1.4.3.3 REVERSIBLE NITROALDOL REACTION 18 1.4.3.4 REVERSIBLE
RESORCINOL AND ALKANEDIAL CONDENSATION I8 1.4.3.5 REVERSIBLE BOROXINE
FORMATION 19 1.4.3.6 PHOSPHAZIDE EXCHANGE 20 1.4.3.7 TRANSBOROXOAROMATIC
ESTERIFKATION 20 BIBLIOGRAFISCHE INFORMATIONEN
HTTP://D-NB.INFO/996919244 DIGITALISIERT DURCH VII CONTENTS 2.2.1 MS
ANALYSIS 25 2.2.2 LC-MS ANALYSIS 25 2.2.3 ANALYSIS BY NMR 28 2.2.4
RESIN-BOUND DCC 31 2.3 EXPERIMENTAL DESIGN 32 2.3.1 IMPORTANCE OF
TEMPLATE CONCENTRATION 32 2.3.2 LIBRARY SIZE 40 2.4 DATA ANALYSIS 44
2.4.1 QUANTIFYING EQUILIBRIUM CONSTANTS 44 2.4.2 DCLS AS SENSORS 45 2.5
CONCLUSIONS 46 ACKNOWLEDGMENTS 46 REFERENCES 46 3 DEVELOPMENT OF
SYNTHETIC RECEPTORS USING DYNAMIC COMBINATORIAL CHEMISTRY 49 ANDREA M.
ESCALANTE AND RICARDO LE. FUNAN 3.1 INTRODUCTION 49 3.2 EXPERIMENTAL
CONSIDERATIONS 51 3.2.1 PREPARATION OF DCLS 51 3.2.1.1 REVERSIBLE
CHEMISTRY 51 3.2.1.2 BUILDING BLOCK DESIGN 57 3.2.1.3 BUILDING BLOCK
CONCENTRATION 58 3.2.1.4 ASSESSING EQUILIBRIUM 59 3.2.2 TEMPLATING OF
THE LIBRARY 60 3.2.2.1 ENSURING MEANINGFUL AMPLIFICATIONS 60 3.2.2.
CONTENTS VII 4.3 DYNAMIC COMBINATORIAL APPROACHES TO TRANSITION METAL
CATALYSTS 200 4.3.1 DYNAMIC LIBRARIES OF TRANSITION METAL CATALYSTS 102
4.3.1.1 LIBRARY OF MONODENTATE AND COVALENT BIDENTATE LIGANDS 102
4.3.1.2 LIBRARY OF SUPRAMOLECULAR BIDENTATE LIGANDS 102 4.3.1.3 LIBRARY
OF DYNAMIC SUPRAMOLECULAR TEMPLATES 103 4.3.1.4 LIBRARY OF DYNAMIC
COVALENT LINKERS 103 4.3.2 SELECTION PROCEDURES VIA INTERMEDIATES AND
TSAS 103 4.3.2.1 TSA APPROACH 104 4.3.2.2 SELECTION OF CATALYST BASED ON
INTERMEDIATE STABILITY 204 4.4 CONCLUSIONS 207 REFERENCES 207 5 DYNAMIC
COMBINATORIAL CHEMISTRY: LIGANDS FOR BIOMOLECULES 209 OLOF RAMSTROEM,
LUIS AMORIM, REMI CARABALLO, AND OSCAR NORBERG 5.1 LIGAND DISCOVERY 209
5.1.1 HIGH-THROUGHPUT CHEMISTRY 209 5.1.2 DYNAMIC TARGET ASSISTANCE 2 20
5.1.3 DYNAMIC FRAGMENT-BASED LIGAND DISCOVERY 2 22 5.2 DCC STRATEGIES IN
TARGETING BIOLOGICAL SYSTEMS 222 5.2.1 STOICHIOMETRIC DCLS 222 5.2.2
POSTMODIFIED DCLS-DYNAMIC REDUCTIVE AMINATION 223 5.2.3 PRE-EQUILIBRATED
AND ITERATED DCLS-DYNAMIC DECONVOLUTION AND PANNING 2 24 5.2.4 DYNAMIC
COMBINATORIAL X-RAY CRYSTALLOGRAPHY 124 5.2.5 DYNAMIC COMBINATORIAL
RESOLUTION-KINETICALLY RESOLVED DCL VIII I CONTENTS 6 POLYMERS FORMED BY
DYNAMIC COMBINATORIAL CHEMISTRY 252 JEAN-LUC WIETOR, NICOLE E.
BOTTERHUIS, AND RINT P. SIJBESMA 6.1 INTRODUCTION 251 6.2 DYNAMICS IN
POLYMERS 252 6.2.1 EXCHANGEABLE COVALENT BONDS-A FAMILIAR FEATURE IN
POLYMER CHEMISTRY 252 6.2.2 NONCOVALENT CHEMISTRY-SUPRAMOLECULAR
POLYMERS 254 6.2.3 COORDINATION POLYMERS 155 6.2.4 EXCHANGEABLE COVALENT
BONDS 255 6.2.5 REVERSIBLE COVALENT CHEMISTRY IN POLYMERS 156 6.2.6
DYNAMICS PUT TO USE IN SELF-HEALING MATERIALS 158 6.2.6.1 REVERSIBLE
COVALENT APPROACH 258 6.2.6.2 NONCOVALENT APPROACH 259 6.3 BIASING
COMPOSITION BY MOLECULAR RECOGNITION 160 6.3.1 SELF-SORTING 160 6.3.2
TEMPLATING 262 6.3.2.1 TEMPLATING IN BIOPOLYMERS 262 6.3.2.2 TEMPLATING
IN NON-NATURAL POLYMERS 262 6.3.3 MOLECULARLY IMPRINTED POLYMERS 263 6.4
CONCLUSIONS AND OUTLOOK 165 REFERENCES 266 7 ANALYTICAL APPLICATIONS OF
DYNAMIC COMBINATORIAL CHEMISTRY 269 KAY SEVERIN 7.1 INTRODUCTION 169 7.2
FLUORESCENT SENSORS 270 7.3 COLORIMERRIC SENSORS 272 7.4 MOLECULAR
TIMERS 282 7.5 CONCLUSIONS 282 REFERENCES 183 8 TRENDS AND PERSPECTIVES
185
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| isbn | 9783527321223 |
| language | English |
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| spelling | Dynamic combinatorial chemistry ed. by Joost N. H. Reek ... Weinheim Wiley-VCH 2010 X, 201 S. txt rdacontent n rdamedia nc rdacarrier Combinatorial chemistry Dynamische kombinatorische Chemie (DE-588)7696101-1 gnd rswk-swf Werkstoffkunde (DE-588)4079184-1 gnd rswk-swf Naturstoffchemie (DE-588)4171332-1 gnd rswk-swf Kombinatorische Synthese (DE-588)4513555-1 gnd rswk-swf Dynamische kombinatorische Chemie (DE-588)7696101-1 s DE-604 Kombinatorische Synthese (DE-588)4513555-1 s Werkstoffkunde (DE-588)4079184-1 s Naturstoffchemie (DE-588)4171332-1 s b DE-604 Reek, Joost N. H. 1967- (DE-588)140809767 edt DNB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018718420&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Dynamic combinatorial chemistry Combinatorial chemistry Dynamische kombinatorische Chemie (DE-588)7696101-1 gnd Werkstoffkunde (DE-588)4079184-1 gnd Naturstoffchemie (DE-588)4171332-1 gnd Kombinatorische Synthese (DE-588)4513555-1 gnd |
| subject_GND | (DE-588)7696101-1 (DE-588)4079184-1 (DE-588)4171332-1 (DE-588)4513555-1 |
| title | Dynamic combinatorial chemistry |
| title_auth | Dynamic combinatorial chemistry |
| title_exact_search | Dynamic combinatorial chemistry |
| title_full | Dynamic combinatorial chemistry ed. by Joost N. H. Reek ... |
| title_fullStr | Dynamic combinatorial chemistry ed. by Joost N. H. Reek ... |
| title_full_unstemmed | Dynamic combinatorial chemistry ed. by Joost N. H. Reek ... |
| title_short | Dynamic combinatorial chemistry |
| title_sort | dynamic combinatorial chemistry |
| topic | Combinatorial chemistry Dynamische kombinatorische Chemie (DE-588)7696101-1 gnd Werkstoffkunde (DE-588)4079184-1 gnd Naturstoffchemie (DE-588)4171332-1 gnd Kombinatorische Synthese (DE-588)4513555-1 gnd |
| topic_facet | Combinatorial chemistry Dynamische kombinatorische Chemie Werkstoffkunde Naturstoffchemie Kombinatorische Synthese |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018718420&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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