Bone repair biomaterials:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Boca Raton, FL [u.a.]
CRC Press
2009
Oxford [u.a.] Woodhead Publishing |
| Series: | Woodhead publishing in materials
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XIV, 478 S. Ill., graph. Darst. |
| ISBN: | 9781439801956 9781845693855 |
Staff View
MARC
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Record in the Search Index
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|---|---|
| adam_text | Titel: Bone repair biomaterials
Autor: Planell, Josep A.
Jahr: 2009
Contents
Contributor contact details xi
Part I Introduction
1 Challenges of bone repair 3
J. A. Planell and M. Navarro, Institute for Bioengineering of
Catalonia, Spain
1.1 Introduction 3
1.2 Social and economical impact of musculoskeletal disease 3
1.3 Economic bürden of musculoskeletal disease 6
1.4 Social aspects of dental and maxillofacial conditions 9
1.5 Some clinical challenges of bone repair 11
1.6 Conclusions and future trends 17
1.7 Sources of further information and advice 19
1.8 References 19
2 Bone anatomy, physiology and adaptation to
mechanical loading 25
R. K. Fuchs and S. J. Warden, Indiana University, USA, and C. H.
Turner, Indiana University-Purdue University Indianapolis, USA
2.1 Introduction 25
2.2 Macroscopic bone anatomy 26
2.3 Microscopic bone anatomy 28
2.4 Bone physiology 37
2.5 Bone adaptation to mechanical loading 44
2.6 Conclusions 54
2.7 References 55
3 Bone repair and regeneration 69
N. Baldini, E. Cenni, G. Ciapetti, D. Granchi and L. Savarino,
Istituto Ortopedico Rizzoli, Italy
3.1 Introduction 69
vi Contents
3.2 Bone healing 70
3.3 Role of stem cells in bone repair 76
3.4 Molecular events of bone repair and regeneration 81
3.5 Role of growth factors in bone repair and regeneration 89
3.6 References 97
4 Biomechanical aspects of bone repair 106
D. Lacroix, Institute for Bioengineering of Catalonia (IBEC), Spain
4.1 Bone composition and structure 106
4.2 Biomechanical properties of bone 109
4.3 Bone damage and repair 114
4.4 Conclusions 116
4.5 Bibliography 116
4.6 References 117
Part II Biomaterials
5 Properties and characterisation of bone repair
materials 121
A. A. White and S. M. Best, University of Cambridge, UK
5.1 Introduction 121
5.2 Mechanical properties 122
5.3 Molecular and microstructural properties 132
5.4 Physiological effects 140
5.5 Comparing material classes 146
5.6 Summary 150
5.7 References 151
6 Metals as bone repair materials 154
J. L. GonzAlez-Carrasco, Centro Nacional de Investigaciones
Metalurgicas (CENIM-CSIC) and CIBER-BBN, Spain
6.1 Introduction 154
6.2 Common metallic biomaterials 157
6.3 Other metallic materials 163
6.4 Properties 168
6.5 Trends in the development of metallic biomaterials 177
6.6 Conclusions 186
6.7 Acknowledgements 187
6.8 References 187
Contents vii
7 Ceramics as bone repair materials 194
M. Vallet-Reg( and A. J. Salinas, Universidad Complutense,
Spain and CIBER-BBN, Spain
7.1 Overview of ceramics in biomedical engineering 194
7.2 Almost bioinert ceramics: first generation bioceramics 200
7.3 Biodegradable and bioactive ceramics: second generation
bioceramics 205
7.4 Ceramics in bone regeneration: third generation ceramics 214
7.5 Bioceramics today 220
7.6 Acknowledgements 220
7.7 References 220
8 Polymers for bone repair 231
M. A. Mateos-Timoneda, Institute for Bioengineering of Catalonia
(IBEC) and CIBER-BBN, Spain
8.1 Introduction 231
8.2 Ultra high molecular weight polyethylene (UHMWPE) 232
8.3 Acrylic polymers as bone cement 237
8.4 Biodegradable polymers 241
8.5 Conclusions 247
8.6 References 247
9 Composite biomaterials for bone repair 252
R. De Santis, V. Guarino and L. Ambrosio, IMCB-CNR Institute
of Composite and Biomedical Materials, Italy
9.1 Introduction 252
9.2 Basic concept of composite material 253
9.3 Composite biomaterials in bone repair 255
9.4 Non-degradable composites 257
9.5 Biodegradable composites 259
9.6 References 266
10 Cements as bone repair materials 271
M. P. Ginebra, Technical University of Catalonia, Spain
10.1 Definition and advantages of bone cements in
orthopaedic surgery 271
10.2 Calcium phosphate versus acrylic bone cements:
historical perspective and present applications 272
10.3 Acrylic bone cements 275
10.4 Calcium phosphate bone cements 285
10.5 References 298
viii Contents
11 Bioactive polymer coatings to improve bone repair 309
G. Helary and V. Migonney, Institut Galilee, France
11.1 Introduction: concept of biocompatibility of biomaterials
for bone repair 309
11.2 Bioactive materials for bone repair 310
11.3 Need for bone integration and repair biomaterials 311
11.4 Available and/or new materials 312
11.5 Bioactive polymer approach 314
11.6 New approach: grafting bioactive polymers onto titanium
implants 317
11.7 Conclusion 321
11.8 References 321
12 Long-term performance and failure of orthopaedic
devices 324
D. Taylor, Trinity College Dublin, Ireland
12.1 Introduction 324
12.2 Long-term failure modes 325
12.3 Stress analysis, simulations and other design methodologies 334
12.4 Case study 1: fatigue design in the artificial hip joint 336
12.5 Case study 2: wear in ultra-high molecular weight
polyethylene 340
12.6 Conclusions and future trends 343
12.7 References 344
Part III Clinical applications
13 Using bone repair materials in orthopaedic surgery 349
A. Merolli, The Catholic University in Rome, Italy, and
P. Tranquilli Leali, University of Sassari, Italy
13.1 Introduction 349
13.2 Operative techniques 351
13.3 Materials 353
13.4 Devices 366
13.5 Conclusions 375
13.6 References 376
14 Bone tissue engineering 378
M. Santin, University of Brighton, UK
14.1 Introduction 378
14.2 State-of-the-art of biomaterials for bone tissue engineering 381
14.3 Cells for bone tissue engineering 401
Contents ix
14.4 Bioactive molecules for tissue engineering 405
14.5 Scaffolds for bone repair 408
14.6 Bioreactors 412
14.7 Clinical applications 413
14.8 Conclusions 416
14.9 References 416
15 Retrieval and analysis of orthopaedic implants 423
A. Palmquist, P. Thomsen and R. BrAneniaRk, Sahlgrenska
Academy at University of Gothenburg, S^eden, H. Engqvist,
Uppsala University, Sweden, and J. LausMaa, SP Technical
Research Institute of Sweden, Sweden
15.1 Introduction 423
15.2 Retrieval 425
15.3 Tissue preservation 425
15.4 Analysis 426
15.5 Examples of results 430
15.6 Acknowledgements 437
15.7 References 437
16 Ethical issues in bone repair and bone tissue
engineering 441
L. Trommelmans, J. Selling and K. DieriCKx, Katholieke
Universiteit Leuven, Belgium
16.1 Introduction: the ethical analysis of bone repair 441
16.2 Cells in bone tissue engineered products (BTEPs) 443
16.3 Clinical trials with bone tissue engineered products 450
16.4 Informed consent in clinical trials 454
16.5 Follow-up of trial participants 457
16.6 Access to therapy 458
16.7 Conclusion 460
16.8 References 460
Index 465
|
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| illustrated | Illustrated |
| indexdate | 2024-07-09T22:05:11Z |
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| isbn | 9781439801956 9781845693855 |
| language | English |
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| physical | XIV, 478 S. Ill., graph. Darst. |
| publishDate | 2009 |
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| spelling | Bone repair biomaterials principal ed.: Josep A. Planell ... Boca Raton, FL [u.a.] CRC Press 2009 Oxford [u.a.] Woodhead Publishing XIV, 478 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Woodhead publishing in materials Biokompatibilität (DE-588)4221531-6 gnd rswk-swf Knochenersatz (DE-588)4164283-1 gnd rswk-swf Knochenersatz (DE-588)4164283-1 s Biokompatibilität (DE-588)4221531-6 s DE-604 Planell, Josep A. Sonstige oth Erscheint auch als Online-Ausgabe 978-1-84569-661-0 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018672498&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Bone repair biomaterials Biokompatibilität (DE-588)4221531-6 gnd Knochenersatz (DE-588)4164283-1 gnd |
| subject_GND | (DE-588)4221531-6 (DE-588)4164283-1 |
| title | Bone repair biomaterials |
| title_auth | Bone repair biomaterials |
| title_exact_search | Bone repair biomaterials |
| title_full | Bone repair biomaterials principal ed.: Josep A. Planell ... |
| title_fullStr | Bone repair biomaterials principal ed.: Josep A. Planell ... |
| title_full_unstemmed | Bone repair biomaterials principal ed.: Josep A. Planell ... |
| title_short | Bone repair biomaterials |
| title_sort | bone repair biomaterials |
| topic | Biokompatibilität (DE-588)4221531-6 gnd Knochenersatz (DE-588)4164283-1 gnd |
| topic_facet | Biokompatibilität Knochenersatz |
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