Target pattern recognition in innate immunity:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
New York, NY
Springer Science+Business Media [u.a.]
2009
|
| Series: | Advances in experimental medicine and biology
653 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XX, 202 S. Ill., graph. Darst. |
| ISBN: | 9781441909008 |
Staff View
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| 245 | 1 | 0 | |a Target pattern recognition in innate immunity |c ed. by Uday Kihore |
| 264 | 1 | |a New York, NY |b Springer Science+Business Media [u.a.] |c 2009 | |
| 300 | |a XX, 202 S. |b Ill., graph. Darst. | ||
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| 490 | 1 | |a Advances in experimental medicine and biology |v 653 | |
| 650 | 2 | |a Immunity, Innate |a genetics | |
| 650 | 2 | |a Gene Targeting | |
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| 650 | 4 | |a Immune recognition | |
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Record in the Search Index
| _version_ | 1804140733366534144 |
|---|---|
| adam_text | CONTENTS
1.
MACROPHAGE
PATTERN RECOGNITION RECEPTORS
IN IMMUNITY, HOMEOSTASIS AND SELF TOLERANCE
Subhankąr
Mukhopadhyay, Annette Pliiddemann and Siamon Gordon
..····...····.....».,...···,....··*···....·.....·..·,·,.
....... ······..·.·■....··■·„.····..■...··,·.·..·„·....·.··..· .·· 1
Introduction
..........................................................................................................................1
The Scavenger Receptor Family
.........................................................................................3
Class A Scavenger Receptors
..............................................................................................4
SR-A(SR-AHI)
....................................................................................................................4
MARCO
................................................................................................................................5
SRCL-I/CLP-1
.....................................................................................................................5
C-Type Lectin Receptors
........•...•...•.......•..4...........·...*..·.·....·..»......»...........·........................6
C
-Туре
Lectíns
with a Single CRD
.....................................................................................7
C
-Туре
Lectíns
with Multiple CRDs
..................................................................................7
NK-Like
C
-Туре
Lectin-Like Receptors
..........................................................................10
Self Tolerance in Innate Immunity
...................................................--------.----------.... 10
Conclusion
.......................................■.....■■...........■■■.....·,............·....................■...............*... 11
2.
PATTERN RECOGNITION BY TOLL-LIKE RECEPTORS
...................15
Stefan Bauer, Thomas
Müller
and
Svetlana
Hamm
Abstract............................................................................................................
...................15
Introduction.■......■·м...■■»..■.·.■н···..■»···■■··.·■».■м·.».···■■»·.■·..н.··■·■..···>■...··■■■■■.*.»■■.···.■■.^■■»■.·· 15
Toll-Like Receptors and Their Ligands ™.
_______..........._____.....______......_____.. 15
Bacterial Recognition by TLRs
________________________________________.... 16
Viral Recognition by TLRs
............................................................................................... 18
Recognition of Fungi and Protozoan Parasites by TLRs
...----------.---------------------19
Cellular Localization of TLRs
___________________________________________20
Recognition of Endogenous Ligands by TLRs and Involvement in Autoimniunity
__20
TLR Signaling
.....,............«.......................................................—.........................■·........... 23
Interferon
Production by TLRs
_____________....—.----------------..........................„24
TT,R Stnipfiire
. . _. _............................................................25
TLR Expression
ία
Cells of the Adaptive Immune System.
.........................................,.26
Cannelli
чшп
.»
u
». .
M«
.т..
»■■«..-..·■..■·■··»·»···»·■■·■.■·····■·■·■··■■>■.···■■■■■■·■■ 27
ívű
xviü
Contents
3.
NOD-LIKE RECEPTORS—PIVOTAL GUARDIANS
OF THE IMMUNOLOGICAL INTEGRITY
OF BARRIER ORGANS
........................................................................35
Philip
Rosenstiel
and Stefan
Schreiber
Abstract
..........................................................·..............................·..................................... 35
Introduction
........................................................................................................................35
NOD-Like Receptors
—
Phylogenetically Ancient Molecular Platforms
of the Innate Immune System
...................................................................................36
Modular Domain Structure
...............................................................................................37
NLRs and the Recent Rise of Barrier Diseases
...............................................................40
Plasticity of NLR Function
................................................................................................42
Conclusion
..........................................................................................................................44
4.
TOLL-LIKE RECEPTORS AND NOD-LIKE RECEPTORS:
DOMAIN ARCHITECTURE AND CELLULAR SIGNALLING
......48
Tanja Langefeld,
Walid
Mohamed,
Rohit Ghai and
Trinad
Chakraborty
Abstract
...............................................................................................................................48
Introduction........
................................................................................................................48
Toll-Like Receptors
............................................................................................................48
Myd88 Dependent TLR Signalling
...................................................................................52
Myd88 Independent TLR Signalling
................................................................................53
Nod-Like Receptors
...........................................................................................................53
Conclusion
..........................................................................................................................55
5.
HUMORAL PATTERN RECOGNITION MOLECULES:
MANNAN-BINDING LECTIN AND FICOLINS
...............................58
Steffen Thiel
and Mihaela Gadjeva
Abstract
...............................................................................................................................58
Introduction.......................................................
.................................................................58
Biochemistry
.......................................................................................................................59
Biology....................
...........................................................................„....„„..„..„„„.....„..„. 63
Conclusion
..........................................................................................................................68
6.
LUNG SURFACTANT PROTEINS A AND
D
AS PATTERN
RECOGNITION PROTEINS
................................................................74
Patrick Waters, Mudit Vaid, Uday Kishore and
Tarana Madan
Abstract................................
...............................................................................................74
Introduction.....................
..........·*.»■■··■■.■··■.■··»......■■......·.........................................74
Collectin Structure Overview
...........................................................................................75
N-Terminal Region...
____.___.________.____________.________.............................75
Collagen Region
....—.......·........................................................„..„...„...„.„........„.„,.„..„.. 75
NeckRegion......,.......,.....,..................,................................,,,..,,..,,...,.^
.............................77
Carbohydrate Recognition Domain (CRD)
________.________________________77
Contents xix
SP-A and SP-D Bind
Lipid
via Their CRDs
....................................................................80
Calcium
Ions
Are Required for CRD Function...............................................................
80
Factors Affecting Interaction with Polysaccharides
.......................................................80
Directing the Immune Response
.......................................................................................82
Specific Examples of SP-A and SP-D as PRRs
______________________________82
Fungus and Yeast
...............................................................................................................86
Viruses
.................................................................................................................................87
SP-A and SP-D in Protection against Allergens and Pulmonary
Hypersensitivity
..........................................................................................................88
Phenotype and Susceptibility of SP-A and SP-D Gene Deficient Mice
.........................89
Conclusion
...............................................................,.......................................................... 91
7.
PATTERN RECOGNITION BY PENTRAXINS
........................................98
Alok Agrawal, Prem Prakash Singh, Barbara Bottazzi, Cecilia Garlanda
and Alberto
Mantovani
Abstract
...............................................................................................................................98
Pentraxins
...........................................................................................................................98
Short Pentraxins: CRP and SAP
......................................................................................99
Long Pentraxin: PTX3
.....______________________...._____._____._____.............103
Conclusion
........................................................................................................................107
8.
TARGET PATTERN RECOGNITION BY COMPLEMENT
PROTEINS OF THE CLASSICAL AND ALTERNATIVE
PATHWAYS
............................................................................................117
Yu-Hoi Kang,
Lee Aun
Tan, Maria V. Carroll, Madeleine E. Gentle
and Robert B. Sim
Abstract
.............................................................................................................................117
The Complement System
...............................................................................—.............117
Clq and Cl Structure...
...................................................................................................118
Biosynthesis of Clq
..........................................................................................................118
Target Recognition by Clq
_____________..................................................................120
Structural Basis of Clq Binding to Targets
_________...........______._____........... 122
Clq Receptors
..................................................................................................................123
Clq across the Animal Kingdom..
......................---------------------..............................124
Properdin
and the Alternative Pathway
---------------------------------------------------124
9.
PATTERN RECOGNITION IN PHAGOCYTIC CLEARANCE
OF ALTERED SELF.
______________________..................................129
Yoshinobu Nakanishi, Peter M. Henson andAkiko Shiratsuchi
Abstract........
..........................................■.■ ■·.................................................................... 129
Roles and Mechanisms of Phagocytosis
-----------------------------------------......—..... 129
Recognition of Altered Self by Phagocytes
--------------------.---------------...........-----132
Consequences of Phagocytic Clearance of Apoptotic Cells..........................................
137
Fate of Necrotic Cells or Cells Dying by Other Modes
-----------------------------------137
н
Contents
10.
STRUCTURAL BASIS OF PATTERN RECOGNITION
BY INNATE IMMUNE MOLECULES
..............................................139
Eamon P. McGreal
Ahsfrapf
.........................................................................139
Introduction
......................................................................................................................13
Molecules Containing Leucine Rich Repeats (LRRs)
...................................................140
Carbohydrate Recognition by
C
-Туре
Lectin and
C
-Туре
Lectin-Like Molecules
..... 147
Emerging Innate Immune Pattern Recognition Molecules
..........................................151
Conclusion
........................................................................................................................155
11.
LESSONS FROM THE FLY: PATTERN RECOGNITION
IN
DROSOPHILA
MELANOGASTER
_________________________162
Subhamoy Pal and Louisa P. Wu
Introduction
·.··..··.······...·..······.··....···.···.···...·········.·········.·...····.....................»............... ... 162
The Immune Response in the Fly
...................................................................................163
The Pattern Recognition Receptors
...............................................................................164
Conclusion
........................................................................................................................ 171
12.
IMMUNE RECOGNITION OF PLASMODIUM-INFECTEO
ERYTHROCYTES
...............................................................................175
Damien V. Cordery and
Britta
С.
Urban
Malaria
..............................................................................................................................175
Clinical Immunity to P. falciparum Infection
................................................................175
Involvement of Pattern Recognition Receptors in Plasmodium Infection
..................177
Recognition of Piasmodium-iiRRCs by Toll-Like Receptors
.........................................178
Recognition of Plasmodium-iRBCs by Scavenger Receptors
.......................................179
Conclusion
........................................................................................................................179
13.
INNATE IMMUNE RECOGNITION IN TUBERCULOSIS
INFECTION
..........................................................................................185
Anthony G. Tsolaki
Abstract
__...............................__________....................................................................185
Introduction·........™.......™...........,........««...........,.™,.......,.«
...........................................185
Receptor-Mediated Phagocytosis of
M
tuberculosis
....................................................186
Complement Receptors
.....................................................„....„„,„.„..„,„„,„„„„.„„„,.„. 186
Mannose Receptors.
____________________________,_____...................................186
Scavenger Receptors
........................................................................................................187
Survival of M. tuberculosis inside the Phagosome.
........................................................188
Immune Recognition of
M
tuberculosis
____________________..............................189
Cytokines Induced in Response to M. tuberculosis Infection
___________...............191
Conclusion
—..·.■..·.·■.....·... ...........«.«..........................„................„„...„.....„„....„„„„„.„ 194
INDEX
_____________________________________________________199
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| id | DE-604.BV035792025 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T22:04:40Z |
| institution | BVB |
| isbn | 9781441909008 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018651345 |
| oclc_num | 335679011 |
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| owner | DE-12 DE-355 DE-BY-UBR |
| owner_facet | DE-12 DE-355 DE-BY-UBR |
| physical | XX, 202 S. Ill., graph. Darst. |
| publishDate | 2009 |
| publishDateSearch | 2009 |
| publishDateSort | 2009 |
| publisher | Springer Science+Business Media [u.a.] |
| record_format | marc |
| series | Advances in experimental medicine and biology |
| series2 | Advances in experimental medicine and biology |
| spelling | Target pattern recognition in innate immunity ed. by Uday Kihore New York, NY Springer Science+Business Media [u.a.] 2009 XX, 202 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Advances in experimental medicine and biology 653 Immunity, Innate genetics Gene Targeting Immune recognition Natural immunity Angeborene Immunität (DE-588)4739713-5 gnd rswk-swf Targetzelle (DE-588)4304980-1 gnd rswk-swf Angeborene Immunität (DE-588)4739713-5 s Targetzelle (DE-588)4304980-1 s DE-604 Kishore, Uday Sonstige (DE-588)173953034 oth Advances in experimental medicine and biology 653 (DE-604)BV000003102 653 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018651345&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Target pattern recognition in innate immunity Advances in experimental medicine and biology Immunity, Innate genetics Gene Targeting Immune recognition Natural immunity Angeborene Immunität (DE-588)4739713-5 gnd Targetzelle (DE-588)4304980-1 gnd |
| subject_GND | (DE-588)4739713-5 (DE-588)4304980-1 |
| title | Target pattern recognition in innate immunity |
| title_auth | Target pattern recognition in innate immunity |
| title_exact_search | Target pattern recognition in innate immunity |
| title_full | Target pattern recognition in innate immunity ed. by Uday Kihore |
| title_fullStr | Target pattern recognition in innate immunity ed. by Uday Kihore |
| title_full_unstemmed | Target pattern recognition in innate immunity ed. by Uday Kihore |
| title_short | Target pattern recognition in innate immunity |
| title_sort | target pattern recognition in innate immunity |
| topic | Immunity, Innate genetics Gene Targeting Immune recognition Natural immunity Angeborene Immunität (DE-588)4739713-5 gnd Targetzelle (DE-588)4304980-1 gnd |
| topic_facet | Immunity, Innate genetics Gene Targeting Immune recognition Natural immunity Angeborene Immunität Targetzelle |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018651345&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV000003102 |
| work_keys_str_mv | AT kishoreuday targetpatternrecognitionininnateimmunity |