Natural compounds and their role in apoptotic cell signaling pathways:
"This volume includes contributions about the effect of natural compounds on cancer cells as well as on neurodegenerative diseases. More specifically, natural compounds are also described as inducers of cell death. Topics related to diet in health, disease, and inflammation linked to cancer are...
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Boston, Mass.
Blackwell
2009
|
| Schriftenreihe: | Annals of the New York Academy of Sciences
1171 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Zusammenfassung: | "This volume includes contributions about the effect of natural compounds on cancer cells as well as on neurodegenerative diseases. More specifically, natural compounds are also described as inducers of cell death. Topics related to diet in health, disease, and inflammation linked to cancer are also discussed."--Pref. |
| Beschreibung: | XII, 660 S. Ill., graph. Darst. |
| ISBN: | 9781573317375 1573317373 |
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| adam_text | Titel: Natural compounds and their role in apoptotic cell signaling pathways
Autor: Diederich, Marc
Jahr: 2009
^^.^NNAfefr-eiyHE NEW YORK ACADEMY OF SCIENCES
Deutsche t Volume 1171
1 Koto J 6
%y ¦ !
• Natural Compounds and Their Role in
Apoptotic Cell Signaling Pathways
Editor
Marc Diederich
This volume presents manuscripts stemming from the conference Apoptosis 2008: From Mechanisms
to Applications, held on January 23-26, 2008 at the European Conference Centre in Luxembourg.
CONTENTS
Preface. By Marc Diederich 1
Part I. Apoptotic Cell Signaling Pathways in Health and Disease
AIF: Not Just an Apoptosis-Inducing Factor. By Nicholas Joza, J. Andrew
Pospisilik, Emilie Hangen, Toshikatsu Hanada, Nazanine Modjtahedi, Josef
M. Penninger, and Guido Kroemer 2
Changes of Mitochondria and Relocation of the Apoptosis-Inducing Factor
during Apoptosis. By A. Ivana Scovassi, Cristiana Soldani, Paola Veneroni,
Maria Grazia Bottone, and Carlo Pellicciari 12
Neuronal Apoptosis in Alzheimer s Disease: The Role of Age-Related
Mitochondrial Metabolic Competence. By Carlo Bertoni-Freddari, Patrizia
Fattoretti, Tiziana Casoli, Giuseppina Di Stefano, Marta Balietti, Belinda
Giorgetti, and Gemma Perretta 18
Leukocyte Elastase Inhibitor: A New Regulator of PARP-1. By Chloe Lepretre,
Giuseppina Sidoli, A. Ivana Scovassi, and Alicia Torriglia 25
Distribution of Centromeric Proteins and PARP-1 during Mitosis and Apoptosis.
By Federica Perdoni, Maria Grazia Bottone, Cristiana Soldani, Paola
Veneroni, Claudia Alpini, Carlo Pellicciari, and Anna Ivana Scovassi 32
Is There a Role for Nuclear Factor kB in Tumor Necrosis Factor-Related
Apoptosis-Inducing Ligand Resistance? By Amandine Plantivaux, Eva
Szegezdi, Afshin Samali, and Laurence Egan 38
TRAIL-Induced Apoptosis: Between Tumor Therapy and Immunopathology.
By Nadia Corazza, Daniela Kassahn, Sabine Jakob, Anastasia Badmann, and
Thomas Brunner 50
V
vi Annals of the New York Academy of Sciences
Signal Transducer and Activator of Transcription-3, Inflammation, and Cancer.
How Intimate Is the Relationship? By Bharat B. Aggarwal, Ajaikumar B.
Kunnumakkara, Kuzhuvelil B. Harikumar, Shan R. Gupta, Sheeja T.
Tharakan, Gemile Koca, Sanjit Dey, and Bokyung Sung 59
The Apoptotic Paradox in Retinoblastoma. By Rita S. Sitorus, Saukani Gumay,
and Paul van der Valk 77
eEFlA2 as a Putative Oncogene. By Mee-Hyun Lee and Young-Joon Surh 87
Stanniocalcin, a Potential Ovarian Angiogenesis Regulator, Does Not Affect
Endothelial Cell Apoptosis. By Giuseppina Basini, Simona Bussolati, Sujen
Eleonora Santini, and Francesca Grasselli 94
Expression of MMP-2, MMP-9, and Urokinase-Type Plasminogen Activator in
Cervical Intraepithelial Neoplasia. By Jae Hong No, Hoenil Jo, Su-Hyeong
Kim, In-Ae Park, Daehee Kang, Chae Hyeong Lee, Seung-Su Han, Jae
Weon Kim, Noh-Hyun Park, Soon-Beom Kang, and Yong-Sang Song 100
Expression of Vascular Endothelial Growth Factor and Hypoxia Inducible
Factor-la in Cervical Neoplasia. Byjae Hong No, Hoenil Jo, Su-Hyeong
Kim, In-Ae Park, Daehee Kang, Seung-Su Han, Jae Weon Kim, Noh-Hyun
Park, Soon-Beom Kang, and Yong-Sang Song 105
Cyclooxygenase-2 Expression in Cervical Intraepithelial Neoplasia. By Kidong ¦
Kim, Yong-Tarkjeon, In-Ae Park, Jae Weon Kim, Noh-Hyun Park,
Soon-Beom Kang, Hyo-Pyo Lee, and Yong-Sang Song Ill
Transforming Growth Factor-pi and Regulators of Apoptosis: P53, Bax, and
Bcl-xL in Colorectal Cancers. By Stanislaw Sulkowski, Andrzej Wincewicz,
Mariola Sulkowska, and Mariusz Koda 116
Part II. Natural Compounds as Regulators of Cancer
Cell Signaling Pathways
Roscovitine Triggers Apoptosis in B-Cell Chronic Lymphocytic Leukemia Cells i
with Similar Efficiency as Combinations of Conventional Purine Analogs
with Cyclophosphamide. By Jolanta D. Zolnierczyk, Jerzy Z. Blonski, Tadeusz
Robak, Zofia M. Kilianska, andjozefa Wesierska-Gadek 124
Inhibition of P-Glycoprotein by Wogonin Is Involved with the Potentiation of
Etoposide-Induced Apoptosis in Cancer Cells. By Eibai Lee, Riyo Enomoto, i
Chika Koshiba, and Hiroyuki Hirano 132 i
Induction of Apoptosis and Inhibition of Invasion in Human Hepatoma Cells by j
Anthocyanins from Meoru. By Dong Yeok Shin, Chung Ho Ryu, Won Sup i
Lee, Dong Chul Kim, Seok Hyun Kim, Young-Sool Hah, Sung Joong Lee,
Sung Chul Shin, Ho Sung Kang, and Yung Hyun Choi 137
Mechanism of a-Lipoic Acid-Induced Apoptosis of Lung Cancer Cells:
Involvement of Ca2+. By Sang Yong Choi, Ji Hoon Yu, and Hyeyoung
Kim 149
Mechanism of p -Carotene-Induced Apoptosis of Gastric Cancer Cells:
Involvement of Ataxia-Telangiectasia-Mutated. By Sung Hee Jang, Joo Weon j
Lim, and Hyeyoung Kim 156
Activator Protein-1 Mediates Docosahexaenoic Acid-induced Apoptosis of
Human Gastric Cancer Cells. By Sun En Lee, Joo Weon Lim, and Hyeyoung i
Kim 163 j
|
Contents vii
Protective Effects of Red Wine Flavonols on 4-Hydroxynonenal-Induced
Apoptosis in PC 12 Cells. By Young Jin Jang, Nam Joo Kang, Ki Won Lee,
and Hyong Joo Lee 170
Piceatannol Attenuates 4-Hydroxynonenal-Induced Apoptosis of PC 12 Cells by
Blocking Activation of c-Jun N-Terminal Kinase. By Young Jin Jang,
Jong-Eun Kim, Nam Joo Kang, Ki Won Lee, and Hyong Joo Lee 176
Chloretta Methanol Extract Reduces Lipid Accumulation in. and Increases the
Number of Apoptotic 3T3-L1 Cells. 5yJeong-Woo Chon, Ju-Hyun Sung,
Eun-Joo Hwang, and Yoo-Kyoung Park 183
Growth-Inhibitory and Proapoptotic Effects of Alpha-Linolenic Acid on
Estrogen-Positive Breast Cancer Cells: Second Look at w-3 Fatty Acid.
^yJi-Yoon Kim, Han Deuk Park, Eunju Park, Jeong-Woo Chon, and Yoo
Kyoung Park 190
Involvement of Both Extrinsic and Intrinsic Apoptotic pathways in Apoptosis
Induced by Genistein in Human Cervical Cancer Cells. By Su-Hyeon Kim,
Su-Hyeong Kim, Sang-Chul Lee, and Yong-Sang Song 196
Effects of 15-Deoxy-A12 14-prostaglandinJ2 on the Expression of p53 in MCF-7
Cells. By Do-Hee Kim, Eun-Hee Kim, Hye-Kyung Na, and Young-Joon
Surh 202
15-Deoxy-A12ll4-prostaglandinJ2 Induces Upregulation of Multidrug
Resistance-Associated Protein 1 via Nrf2 Activation in Human Breast Cancer
Cells. By Na-Young Song, Do-Hee Kirn, Eun-Hee Kim, Hye-Kyung Na, and
Young-Joon Surh 210
Antioxidant and Apoptotic Effects of Korean White Ginseng Extracted with the
Same Ratio of Protopanaxadiol and Protopanaxatriol Saponins in Human
Hepatoma HepG2 Cells. By Myoungsook Lee, Stingbin Sorn, Seungyong
Baek, Soojung Jang, and Sungsoo Kim 217
Part III. Natural Compounds Regulating the Cell Cycle
Selective Cyclin-Dependent Kinase Inhibitors Discriminating between Cell Cycle
and Transcriptional Kinases: Future Reality or Utopia? By Jozefa
Wesierska-Gadek and Vladimir Krystof 228
Is Olomoucine, a Weak GDK2 Inhibitor, Able to Induce Apoptosis in Cancer
Cells? By Stefanie Wandl and Jozefa Wesierska-Gadek 242
Roscovitine Differentially Affects Asynchronously Growing and Synchronized
Human MCF-7 Breast Cancer Cells. By Margarita Maurer, Oxana Komina,
and Jozefa Wesierska-Gadek • 250
Monitoring of Long-Term Effects of Resveratrol on Ceil Cycle Progression of
Human HeLa Cells after Administration of a Single Dose. By Matthias P.
Kramer and Jozefa Wesierska-Ga.dek - 257
Apoptosis and Modulation of Cell Cycle Control by Bile Acids in Human
Leukemia T Cells. By Carmela Fimognari, Monia LenzJ, Giorgio
Cantelli-Forti, and Patrizia Hrelia 264
Lactococcus lactis ssp. lactis Inhibits the Proliferation of SNU-1 Human Stomach
Cancer Cells through Induction of GO/Gl Cell Cycle Arrest and Apoptosis
via p53 and p21 Expression. By Seo Young Kim, Jong-Eun Kim, Ki Won
Lee, and Hyongjoo Lee ¦ 270
viii Annals of the New York Academy of Sciences
Molecular Response of HL-60 Cells to Mitotic Inhibitors Vincristine and Taxol
Visualized with Apoptosis-Related Gene Expressions, Including the New
Member BCL2L12. By Hellinida Thomadaki, Konstantinos V Floros, and
Andreas Scorilas 276
Part IV. Natural Compounds Regulating Apoptotic
Cell Signaling Pathways
Acriflavine-Mediated Apoptosis and Necrosis in Yeast Candida utilis. By Ezzatollah
Keyhani, Sarah Khavari-Nej ad, Jacqueline Keyhani, and Farnoosh
Attar 284
Structural and Functional Alterations of Catalase Induced by Acriflavine, a
Compound Causing Apoptosis and Necrosis. By Farnoosh Attar, Sarah
Khavari-Nejad, Jacqueline Keyhani, and Ezzatollah Keyhani 292
Study of Antiseizure Effects ofMatricaria recutita Extract in Mice. By M- R.
Heidari, Z. Dadollahi, M. Mehrabani, H. Mehrabi, M. Pourzadeh-Hosseini,
E. Behravan, and L. Etemad 300
Plant Polyphenols Effectively Protect HaCaT Cells from Ultraviolet C-Triggered
Necrosis and Suppress Inflammatory Chemokine Expression. By Saveria
Pastore, Alia Potapovich, Vladimir Kostyuk, Valentina Mariani, Daniela
Lulli, Chiara De Luca, and Iiudmila Korkina 305
Estimation of the Combined Effect of Eleutherococcus senticosus Extract and
Cadmium on Liver Cells. By Alina Smalinskiene, Vaiva Lesaiiskaite, Virgilijus
Zitkevicius, Nijole Savickiene, Arunas Savickas, Stanislovas Ryselis, Ilona
Sadauskiene, and Leonid Ivanov 314
Response of Retinoic Acid-Resistant KG1 Cells to Combination of Retinoic Acid
with Diverse Histone Deacetylase Inhibitors. By Jurate Savickiene, Grazina
Treigyte, Karl-Eric Magnusson, and Ruta Navakauskiene 321
Differentiation and Apoptosis in UVA-Irradiated Cells Treated with
Furocoumarin Derivatives. By Giampietro Viola, Alessia Salvador, Daniela
Vedaldi, Francesco DalTAcqua, Nicoletta Bianchi, Cristina Zuccato, Monica :
Borgatti, Ilaria Lampronti, and Roberto Gambari 334
Melatonin as a Modulator of Apoptosis in B-Lymphoma Cells. By Laura
Paternoster, Flavia Radogna, Augusta Accorsi, Maria Cristina Albertini,
Giampiero Gualandi, and Lina Ghibelli 345
Erucylphospho JVJjV^jV-trimethylpropylammonium Shows Substantial
Cytotoxicity in Multiple Myeloma Cells. By Deyan Y. Yosifov, Spiro M.
Konstantinov, and Martin R. Berger 350
Effects of Omega-3 Fatty Acids on Apoptosis of Human Gastric Epithelial Cells
Exposed to Silica-Immobilized Glucose Oxidase. By Ji Hoon Yu, Sin-Gun
Kang, Un-Youngjung, Chul-Ho Jun, and Hyeyoung Kim 359
Part . Dietary Agents in Health and Disease
Apoptosis Does Not Mediate Macrophage Depletion in Rabbit Atherosclerotic
Plaques after Dietary Lipid Lowering. By Wim Martinet, Valerie Croons,
Arnold G. Herman, and Guido R.Y De Meyer 365 :
Studies with Regard to the Apoptosis of Testicular Germ Cells in Rats Fed a Diet !
Enriched with Polyunsaturated Fatty Acids. By Holger Bertelsmann, Dietrich I
Behne, and Antonios Kyriakopoulos 372 j
Contents ix
A Ketogenic Diet Increases Succinic Dehydrogenase Activity in Aging
Cardiomyocytes: Potential Protective Role against Apoptosis-Induced Heart
Failure. By Marta Balietti, Patrizia Fattoretti, Belinda Giorgetti, Tiziana
Casoli, Giuseppina Di Stefano, Moreno Solazzi, Daniela Platano, Giorgio
Aicardi, and Carlo Bertoni-Freddari 377
Changes in Antioxidant Status, Blood Pressure, and Lymphocyte DNA Damage
from Grape Juice Supplementation. By Yoo Kyoung Park, Sun Hee Lee,
Eunju Park, Jung-Shin Kim, and Myung-Hee Kang 385
Part VI. Natural Compounds as Inhibitors of Inflammation
Gene Expression Profiling Related to Anti-inflammatory Properties of Curcumin
in K562 Leukemia Cells. By Marie-Helene Teiten, Serge Eifes, Simone
Reuter, Annelyse Duvoix, Mario Dicato, and Marc Diederich 391
Evaluation of Anti-inflammatory and Analgesic Activity of a Novel Rigid 3,
4-Dihydroxy Chalcone in Mice. By M. R. Heidari, A. Foroumadi, A.
Amirabadi, A. Samzadeh-Kermani, B. S. Azimzadeh, and
A. Eskandarizadeh 399
Tumor Necrosis Factor Inhibitors Block Apoptosis of Human Epithelial Cells of
the Salivary Glands. By Margherita Sisto, Massimo D Amore, Simone
Caprio, Vincenzo Mitolo, Pasquale Scagliusi, and Sabrina Lisi 407
Anti-inflammatory and Anticarcinogenic Effect of Genistein Alone or in
Combination with Capsaicin in TPA-Treated Rat Mammary Glands or
Mammary Cancer Cell Line. By Jin-Tack Hwang, Yun-Kyoung Lee, Jang-In
Shin, and Ockjin Park 415
Inhibitory Mechanism of Omega-3 Fatty Acids in Pancreatic Inflammation and
Apoptosis. By Kyung Suk Park, Joo Weon Lim, and Hyeyoung Kim 421
Interleukin-l|3-Induced Extracellular Matrix Degradation and
Glycosaminoglycan Release Is Inhibited by Curcumin in an Explant Model
of Cartilage Inflammation. By Abigail L. Clutterbuck, Ali Mobasheri, Mehdi
Shakibaei, David Allaway, and Pat Harris 428
Effect of Curcumin on Nuclear Factor kB Signaling Pathways in Human Chronic
Myelogenous K562 Leukemia Cells. By Simone Reuter, Jessica Charlet, Tom
Juncker, Marie-Helene Teiten, Mario Dicato, and Marc Diederich 436
Apoptosis of Human Primary Osteoclasts Treated with Molecules Targeting
Nuclear Factor-icB. By Roberta Piva, Letizia Penolazzi, Monica Borgatti,
Ilaria Lampronti, Elisabetta Lambertini, Elena Torreggiani, and Roberto
Gambari 448
15-Deoxy-A,12-14-prostaglandinj2 Suppresses Nuclear Factor-icB-Mediated
Apoptosis of Helicobacterpylori-Intected Gastric Epithelial Cells. By Boram
Cha, Kyung Hwan Kim, and Hyeyoung Kim 457
Effects of Exercise on Cyclooxygenase-2 Expression and Nuclear Factor-icB DNA
Binding in Human Peripheral Blood Mononuclear Cells. By Si-Young Kim,
Tae-Won Jun, Young-Soo Lee, Hye-Kyung Na, Young-Joon Surh, and Wook
Song 464
Intracellular Prooxidant Activity of Melatonin Induces a Survival Pathway
Involving NF-kB Activation. By Silvia Cristofanon, Francesco Uguccioni,
Claudia Cerella, Flavia Radogna, Mario Dicato, Lina Ghibelli, and Marc
Diederich 472
x Annals of the New York Academy of Sciences
Part VII. MAP Kinase Signaling Pathways
Phloretin Induces Apoptosis in H-Ras MGF10A Human Breast Tumor Cells
through the Activation of p53 via JNK and p38 Mitogen-Activated Protein
Kinase Signaling. By Mi-Sung Kim, Jung Yeon Kwon, Nam Joo Kang, Ki
Won Lee, and Hyongjoo Lee 479
Kidney Bean Husk Extracts Exert Antitumor Effect by Inducing Apoptosis
Involving AMP-Activated Protein Kinase Signaling Pathway. By Yun-Kyoung
Lee, Jin-Taek Hwang, Mee-Sook Lee, Young-Min Kim, and Ockjin
Park 484
Regulatory Effect of the AMPK-COX-2 Signaling Pathway in
Curcumin-Induced Apoptosis in HT-29 Colon Cancer Cells. By Yun-Kyoung
Lee, Song Yi Park, Young-Min Kim, and Ockjin Park 489
Genistein Inhibits Cell Growth by Modulating Various Mitogen-Activated Protein
Kinases and AKT in Cervical Cancer Cells. By Su-Hyeon Kim, Su-Hyeong
Kim, Yong-Beom Kim, Yong-Tark Jeon, Sang-Chul Lee, and Yong-Sang
Song 495
Ginkgolide B Induces Apoptosis via Activation of JNK and p21 -Activated Protein
Kinase 2 in Mouse Embryonic Stem Cells. By Yan-Der Hsuuw, Tzong-Fu
Kuo, Kun-Hsiung Lee, Yen-Chih Liu, Yu-Ting Huang, Ching-Yu Lai, and
Wen-Hsiung Chan 501
Part VIII. Neuroprotection
Neuroprotection by Melatonin on Astrocytoma Cell Death. By Flavia Radogna,
Silvia Nuccitelli, Fabio Mengoni, and Lina Ghibelli 509
Gallic Acid Induces Neuronal Cell Death through Activation of c-Jun N-Terminal
Kinase and Downregulation of Bcl-2. By Min Kyung Kang, Nam Joo Kang,
Young Jin Jang, Ki Won Lee, and Hyongjoo Lee 514
Phosphono Analogues of 2-Oxoglutarate Protect Cerebellar Granule Neurons
upon Glutamate Excitotoxicity. By Victoria I. Bunik, Maria S. Kabysheva,
Eugeny I. Klimuk, Tatiana P. Storozhevykh, and Vsevolod G. Pinelis 521
Part IX. Reactive Oxygen Species
Protective Mechanism of Quercetin and Rutin Using Glutathione Metabolism on
H2O2~induced Oxidative Stress in HepG2 Cells. By Gyo-Nam Kim and
Hae-Dongjang 530
Green Tea Catechin Controls Apoptosis in Colon Cancer Cells by Attenuation of
H2O2-Stimulated COX-2 Expression via the AMPK Signaling Pathway at
Low-Dose H2O2. By In-Ja Park, Yun-Kyoung Lee, Jin-Taek Hwang,
Dae-Young Kwon, Joohun Ha, and Ockjin Park 538
Role of Pancreatitis-Associated Protein 1 on Oxidative Stress-Induced Cell Death
of Pancreatic Acinar Cells. By Joo Weon Lim, Ji Yeon Song, Jeong Yeon Seo,
Hyeyoung Kim, and Kyung Hwan Kim 545
Study of the Photodynamic Effect on the A549 Cell Line by Atomic Force
Microscopy and the Influence of Green Tea Extract on the Production of
Reactive Oxygen Species. By Katerina Tomankova, Hana Kolarova, Robert
Bajgar, Dagmar Jirova, Kristina Kejlova, and Jiri Mosinger 549
Multiple Mechanisms for Hydrogen Peroxide-Induced Apoptosis. By Claudia
Cerella, Simona Coppola, Vittoria Maresca, Milena De Nicola, Flavia i
Radogna, and lina Ghibelli 559 I
Contents xi
Effects of Cotreatment of 12-0-tetradecanoylphorbol-13-acetate and H2O2 on
Apoptotic Regulation via AMP-Activated Protein Kinase-Cyclooxygenase-2
Signals. By Yun-Kyoung Lee, Mee-Sook Lee, Young-Min Kim, and Ock Jin
Park 564
Protective Effect of Lycopene on Oxidative Stress-Induced Cell Death of
Pancreatic Acinar Cells. By Jeong Yeon Seo, Atsushi Masamune, Tooru
Shimosegawa, and Hyeyoung Kim 570
Neuroprotective Activity of Viola mandshurica Extracts on Hydrogen
Peroxide-Induced DNA Damage and Cell Death in PC 12 GeUs.
By Gyeong-Im Jeon, Mi-Young Yoon, Hae-Ryoung Park, Seung-Cheol Lee,
and Eunju Park 576
Subapoptogenic Oxidative Stress Strongly Increases the Activity of the Glycolytic
Key Enzyme Glyceraldehyde 3-Phosphate Dehydrogenase: Possible
Involvement in an Adaptative Response to the Stress. By Claudia Cerella,
Maria D Alessio, Silvia Cristofanon, Milena De Nicola, Flavia Radogna,
Mario Dicato, Marc Diederich, and Lina Ghibelli 583
Involvement of Reactive Oxygen Species in Apoptosis Induced by
Pharmacological Inhibition of Protein Kinase CK2. By Ismail M. Hanif,
Kashif A. Ahmad, Khalil Ahmed, and Shazib Pervaiz 591
Part X. Other Types of Cell Death
Effects of Carbon Nanotubes on Human Monocytes. By Milena De Nicola, Silvia
Nuccitelli, Daniele Mirabile Gattia, Enrico Traversa, Andrea Magrini,
Antonio Bergamaschi, and Lina Ghibelli 600
Biological Effects of a New Vacuolar-H,+-ATPase Inhibitor in Colon Carcinoma
Cell Lines. By Rosanna Supino, A. Ivana Scovassi, Anna Cleta Croce, Laura
Dal Bo, Enrica Favini, Alessandro Corbelli, Carlo Farina, Paola Misiano, and
Franco Zunino 606
Photodynamic Therapy-Induced Apoptosis of HeLa Cells. By Elisa Panzarini,
Bernardetta Tenuzzo, and Luciana Dini 617
Phase I/IIa Study of Combination Chemotherapy with CKD-602 and Cisplatin
in Patients with Recurrent Epithelial Ovarian Cancer. By Hee Seung Kim,
Sok-Bom Kang, Sang-Soo Seo, Seung-Su Han, Jae Weon Kim, Noh-Hyun
Park, Soon-Beom Kang, Hyo-Pyo Lee, and Yong Sang Song 627
Celecoxib Potentiates the Anticancer Effect of Cisplatin on Vulvar Cancer Cells
Independently of Cyclooxygenase. By Su-Hyeon Kim, Su-Hyeong Kim,
Yoo-Choel Song, and Yong-Sang Song 635
Effect of Epidermal Growth Factor Receptor Inhibitor Alone and in Combination
with Cisplatin on Growth of Vulvar Cancer Cells. By Su-Hyeon Kim,
Yoo-Cheol Song, Su-Hyeong Kim, Hoenil Jo, and Yong-Sang Song 642
In Vitro Biochemical and Pharmacological Evaluation of a Novel Cytotoxic
Dinuclear Platinum(II) Complex with 3-Amino-5-methyl-5-phenylhydantoin:
Cytotoxicity, Induction of Apoptosis, DNA Binding, and Processing of the
DNA Adducts. By Georgi Ts. Momekov, Iva Ugrinova, Evdokia A. Pasheva,
Adriana G. Bakalova, Hristo PL Varbanov, Dilyan V Ferdinandov, Darvin SI.
Ivanov, and Spiro M. Konstantinov 649
xii Annals of the New York Academy of Sciences
Corrigendum 659
Erratum 660
The New York Academy of Sciences believes it has a responsibility to provide an open forum for
discussion of scientific questions. The positions taken by the participants in the reported conferences are
their own and not necessarily those of the Academy. The Academy has no intent to influence legislation :
by providing such forums.
j
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| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV035725867 |
| callnumber-first | Q - Science |
| callnumber-label | Q11 |
| callnumber-raw | Q11 |
| callnumber-search | Q11 |
| callnumber-sort | Q 211 |
| callnumber-subject | Q - General Science |
| classification_rvk | WE 5320 |
| ctrlnum | (OCoLC)436030659 (DE-599)HBZHT016054396 |
| dewey-full | 571.936 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 571 - Physiology & related subjects |
| dewey-raw | 571.936 |
| dewey-search | 571.936 |
| dewey-sort | 3571.936 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
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| genre | (DE-588)1071861417 Konferenzschrift 2008 Luxemburg Stadt gnd-content |
| genre_facet | Konferenzschrift 2008 Luxemburg Stadt |
| id | DE-604.BV035725867 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T21:53:03Z |
| institution | BVB |
| isbn | 9781573317375 1573317373 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-018002561 |
| oclc_num | 436030659 |
| open_access_boolean | |
| owner | DE-20 DE-12 DE-11 |
| owner_facet | DE-20 DE-12 DE-11 |
| physical | XII, 660 S. Ill., graph. Darst. |
| publishDate | 2009 |
| publishDateSearch | 2009 |
| publishDateSort | 2009 |
| publisher | Blackwell |
| record_format | marc |
| series2 | Annals of the New York Academy of Sciences |
| spelling | Natural compounds and their role in apoptotic cell signaling pathways ed. by Marc Diederich Boston, Mass. Blackwell 2009 XII, 660 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Annals of the New York Academy of Sciences 1171 "This volume includes contributions about the effect of natural compounds on cancer cells as well as on neurodegenerative diseases. More specifically, natural compounds are also described as inducers of cell death. Topics related to diet in health, disease, and inflammation linked to cancer are also discussed."--Pref. Anticarcinogenic Agents Congresses Antineoplastic Agents Congresses Antineoplastic agents Congresses Apoptosis Congresses Biological Products Congresses Biological products Congresses Cellular signal transduction Congresses Chemoprevention Congresses Signal Transduction Congresses Signaltransduktion (DE-588)4318717-1 gnd rswk-swf Apoptosis (DE-588)4291096-1 gnd rswk-swf Naturstoff (DE-588)4041418-8 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2008 Luxemburg Stadt gnd-content Naturstoff (DE-588)4041418-8 s Apoptosis (DE-588)4291096-1 s Signaltransduktion (DE-588)4318717-1 s DE-604 Diederich, Marc Sonstige oth New York Academy of Sciences Annals of the New York Academy of Sciences 1171 (DE-604)BV002532608 1171 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018002561&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Natural compounds and their role in apoptotic cell signaling pathways Anticarcinogenic Agents Congresses Antineoplastic Agents Congresses Antineoplastic agents Congresses Apoptosis Congresses Biological Products Congresses Biological products Congresses Cellular signal transduction Congresses Chemoprevention Congresses Signal Transduction Congresses Signaltransduktion (DE-588)4318717-1 gnd Apoptosis (DE-588)4291096-1 gnd Naturstoff (DE-588)4041418-8 gnd |
| subject_GND | (DE-588)4318717-1 (DE-588)4291096-1 (DE-588)4041418-8 (DE-588)1071861417 |
| title | Natural compounds and their role in apoptotic cell signaling pathways |
| title_auth | Natural compounds and their role in apoptotic cell signaling pathways |
| title_exact_search | Natural compounds and their role in apoptotic cell signaling pathways |
| title_full | Natural compounds and their role in apoptotic cell signaling pathways ed. by Marc Diederich |
| title_fullStr | Natural compounds and their role in apoptotic cell signaling pathways ed. by Marc Diederich |
| title_full_unstemmed | Natural compounds and their role in apoptotic cell signaling pathways ed. by Marc Diederich |
| title_short | Natural compounds and their role in apoptotic cell signaling pathways |
| title_sort | natural compounds and their role in apoptotic cell signaling pathways |
| topic | Anticarcinogenic Agents Congresses Antineoplastic Agents Congresses Antineoplastic agents Congresses Apoptosis Congresses Biological Products Congresses Biological products Congresses Cellular signal transduction Congresses Chemoprevention Congresses Signal Transduction Congresses Signaltransduktion (DE-588)4318717-1 gnd Apoptosis (DE-588)4291096-1 gnd Naturstoff (DE-588)4041418-8 gnd |
| topic_facet | Anticarcinogenic Agents Congresses Antineoplastic Agents Congresses Antineoplastic agents Congresses Apoptosis Congresses Biological Products Congresses Biological products Congresses Cellular signal transduction Congresses Chemoprevention Congresses Signal Transduction Congresses Signaltransduktion Apoptosis Naturstoff Konferenzschrift 2008 Luxemburg Stadt |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=018002561&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV002532608 |
| work_keys_str_mv | AT diederichmarc naturalcompoundsandtheirroleinapoptoticcellsignalingpathways |