Ion channels: from structure to function
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Oxford [u.a.]
Oxford Univ. Press
2010
|
| Edition: | 1. publ. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis Klappentext |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | XIII, 562 S. |
| ISBN: | 9780199296750 0199296758 |
Staff View
MARC
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| 100 | 1 | |a Kew, James N. C. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Ion channels |b from structure to function |c James N. C. Kew ; Ceri H. Davies |
| 250 | |a 1. publ. | ||
| 264 | 1 | |a Oxford [u.a.] |b Oxford Univ. Press |c 2010 | |
| 300 | |a XIII, 562 S. | ||
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| 500 | |a Includes bibliographical references and index | ||
| 650 | 7 | |a ion channels |2 cabt | |
| 650 | 7 | |a ion transport |2 cabt | |
| 650 | 7 | |a biological transport |2 cabt | |
| 650 | 4 | |a Ion channels | |
| 650 | 4 | |a Ion Channels |x physiology | |
| 650 | 4 | |a Biological Transport, Active | |
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Record in the Search Index
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| adam_text | Contents
List of contributors
ix
PART
1
Introduction to ion channel
structure and function
1
Ion channels: principles, terminology
and methodology
з
Derek
Trezise,
Tim Dale and Martin Main
PART
2
Voltage-gated ion channels
2.1
Voltage-gated K+ channels
21
Bernardo Rudy
2.1.1
The Kv family
(Kvi-Kvő
and
KV8-KV9 subfamilies)
22
Bernardo Rudy, Jonathon Maffie, Yimy
Amarillo,
Brian Clark, Hyo-Young Jeong, Illya Kruglikov, Elaine
Kwon,
Marcela
Nadal
and Edward Zagha
2.1.2
Kv7 channels
57
Jonachan
Robbins
and Cayle
Passmore
2.13
KviO, Kv11 and Kv12 channels
71
Matthew Perry and Michael Sanguinetti
2.1.4
K2P channels
88
Dawon Kang and Donghee Kim
2.2
Voltage-gated calcium channels
104
joel
Baumgart
and Edward Perez-Reyes
2.3
Voltage-gated sodium channels
131
Sulayman Dib-Hajj and Tony Priestley
2.4
CLC chloride channels and chloride/
proton antiporters
172
Michael Pusch
2.5
Hyperpolarization-activated cation channels
18З
Mira
Kuisle and Anita
Lüthi
PART
3
Extracellular ligand-gated
ion channels
3.1
Cys loop receptors
209
3.1.1
Nicotinic acetylcholine receptors
209
Marzia Lecchi,
Jean-Charles
Hoda,
Ronald Hogg and Daniel
Bertrand
3.1.2
5-HT3 receptors
231
John Peters, Michelle Cooper, Matthew Livesey,
Jane Carland and Jeremy Lambert
3.1.3
Glycine
receptors
251
Carmen
Villmann
and Cord-Michael Becker
3.1.4
GABAA receptors
263
Hanns Möhler, Dietmar Benke,
Uwe
Rudolph and Jean-Marc Fritschy
3.2
Glutamate
receptors
277
3.2.1
AMPA
receptors
277
Laura Jane Hanley, Hilary Jackson,
Thomas Chater,
Peter
Hastie
and Jeremy Henley
3.2.2
Kainate receptors
295
Sanja
Selak,
Rocio
Rivera,
Ana Patemain
and Juan Lerma
3.2.3
NMDA receptors
309
Alasdair Gibb
3.3
ATP receptors
326
3.3.1
P2X receptors
326
lain Chessell and Anton Michel
3.4
Others
346
3.4.1
Acid-sensing ion channels
346
Eric Ungueglia and Michel Lazdunski
vúi
CONTENTS
3.4.2
Epithelial sodium channels
364
Stephan Kellenberger
and Laurent
Schild
PART
4
Intracellular ligand-gated ion
channels
4.1
Chloride channels activated by
intracellular ligands
379
Jorge
Arreóla, Juan
Pablo Reyes,
Teresa Rosales-Saavedra and Patricia
Pérez-Cornejo
4.2
Cyclic nucleotide-gated ion channels
392
Zhengchao Wang and Fangxiong Shi
4.3
K^I-KqjS families
4оз
Morten Grunnet,
Dorte
Strabaek,
S0ren-Peter
Olesen
and
Palle Christophersen
4.4
Kir family
424
4.4.1
Kirí, Kir2,
Kir4, Kir5 and Kir7 families
424
Hiroshi Hibino and Yoshihisa Kurachi
4.4.2
КігЗ
family
443
Atsushi Inanobe and Yoshihisa Kurachi
4.4.3
ATP-sensitive K+ channels
454
Michel Vivaudou,
Christophe Moreau
and Andre Terzic
4.5
Ryanodine receptors
474
Stephan Lehnart
and Andrew Marks
4.6
IP3 receptors
492
Randen
Patterson and
Damian
van Rossum
PART
5
Polymodal
gated ion channels
5.1
Transient receptor potential channels
511
Grzegorz Owsianik,
Thomas Voets and
Bernd Nilius
5.2
Connexins and pannexins
538
Elizabeth Hartfield, Annette Weil,
James Uney and Eric Southam
Index
551
Ion channels are intimately involved in everyday physiological functions that enable
us to live a full and varied life. When disease strikes, malfunction of ion channels
or their dependent processes is often involved, either as the cause or effect of the
illness. Thus, billions of dollars have been, and still are being, invested in research to
understand the physiological and pathophysiological functions of ion channels in an
attempt to develop novel therapeutic treatments for a wide range of diseases.
This book provides a comprehensive overview of ion channel structure and function.
It comprises two major parts:
Part one provides an introductory overview of the ion channel superfamily and the
generic aspects of ion channel function. This part also reviews the methodologies
by which ion channel function can be studied from the perspective of performing
detailed biophysical characterization through to the deployment of high throughput
approaches for identifying novel ¡on channel ligands.
Part two of the book provides an in-depth review of the individual ion channel
subfamilies and, as such, is subdivided into four broad sections: Voltage-Gated Ion
Channels, Extracellular Ligand-Gated Ion Channels, Intracellular Ligand-Gated Ion
Channels, and Polymodal-Gated Ion Channels, with each chapter therein focussed
on specific family members. These chapters have been written by world leading
experts and provide a detailed overview of the structure, biophysics, localization,
pharmacology, physiology, and disease relevance of each particular ion channel
subfamily.
Reviewing both the basic principles of ion channel function and providing a detailed
up-to-date review of the physiological and pharmacological aspects of individual
ion channel sub-families, this book constitutes both an excellent introduction to the
field for non-specialists as well as a highly valuable reference text for experienced
researchers already working in the ion channel area.
|
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| spelling | Kew, James N. C. Verfasser aut Ion channels from structure to function James N. C. Kew ; Ceri H. Davies 1. publ. Oxford [u.a.] Oxford Univ. Press 2010 XIII, 562 S. txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index ion channels cabt ion transport cabt biological transport cabt Ion channels Ion Channels physiology Biological Transport, Active Ion Transport Ionenkanal (DE-588)4138699-1 gnd rswk-swf Ionenkanal (DE-588)4138699-1 s b DE-604 Davies, Ceri H. Verfasser aut Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017991839&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017991839&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Kew, James N. C. Davies, Ceri H. Ion channels from structure to function ion channels cabt ion transport cabt biological transport cabt Ion channels Ion Channels physiology Biological Transport, Active Ion Transport Ionenkanal (DE-588)4138699-1 gnd |
| subject_GND | (DE-588)4138699-1 |
| title | Ion channels from structure to function |
| title_auth | Ion channels from structure to function |
| title_exact_search | Ion channels from structure to function |
| title_full | Ion channels from structure to function James N. C. Kew ; Ceri H. Davies |
| title_fullStr | Ion channels from structure to function James N. C. Kew ; Ceri H. Davies |
| title_full_unstemmed | Ion channels from structure to function James N. C. Kew ; Ceri H. Davies |
| title_short | Ion channels |
| title_sort | ion channels from structure to function |
| title_sub | from structure to function |
| topic | ion channels cabt ion transport cabt biological transport cabt Ion channels Ion Channels physiology Biological Transport, Active Ion Transport Ionenkanal (DE-588)4138699-1 gnd |
| topic_facet | ion channels ion transport biological transport Ion channels Ion Channels physiology Biological Transport, Active Ion Transport Ionenkanal |
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