High-yield cell and molecular biology:
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Philadelphia [u.a.]
Lippincott, Williams & Wilkins
2006
|
| Edition: | 2. ed. |
| Series: | High-yield series
|
| Subjects: | |
| Online Access: | Table of contents only Inhaltsverzeichnis |
| Physical Description: | XVIII, 254 S. Ill. |
| ISBN: | 9780781768870 078176887X |
Staff View
MARC
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| 245 | 1 | 0 | |a High-yield cell and molecular biology |c Ronald W. Dudek |
| 246 | 1 | 3 | |a Cell and molecular biology |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Philadelphia [u.a.] |b Lippincott, Williams & Wilkins |c 2006 | |
| 300 | |a XVIII, 254 S. |b Ill. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a High-yield series | |
| 650 | 4 | |a Biologie moléculaire - Résumés, programmes, etc | |
| 650 | 4 | |a Cytologie - Résumés, programmes, etc | |
| 650 | 4 | |a Pathologie - Résumés, programmes, etc | |
| 650 | 4 | |a Molecular biology |v Outlines, syllabi, etc | |
| 650 | 4 | |a Pathology |v Outlines, syllabi, etc | |
| 650 | 4 | |a Cytology |v Outlines, syllabi, etc | |
| 650 | 4 | |a Molecular Biology |v Outlines | |
| 650 | 4 | |a Cytology |v Outlines | |
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Record in the Search Index
| _version_ | 1804139301038981120 |
|---|---|
| adam_text | Preface
..................................................................
vii
φ
The Cell Membrane: Eicosanoids and Receptors/Sipal Transduction
ι
I. The
Lipid
Component of the Cell Membrane
................................1
II. The Protein Component of the Cell Membrane
...............................3
III. Membrane Transport Proteins
............................................3
IV. G-Protein-Linked Receptors
............................................12
V. Types of G-Protein—Linked Receptors
.....................................14
VI. Enzyme-Linked Receptors
..............................................19
VII.
Low-Density Lipoprotein (LDL) Receptor
..................................21
VIII.
Summary Table
.......................................................21
Q
Cytoplasm and Organelles
.23
Θ
I. Cytoplasm
..........................................................23
II. Ribosomes
..........................................................23
III. Rough Endoplasmic Reticulum
..........................................24
IV. Golgi Complex
.......................................................25
V. Smooth Endoplasmic Reticulum (sER)
....................................25
VI. Mitochondria
........................................................26
VII.
Lysosomes
..........................................................27
VIII.
Peroxisomes
.........................................................28
IX. Cytoskeleton
........................................................28
X. Cell Inclusions
.......................................................30
XI. Selected Photomicrographs
.............................................31
................................................................33
I. Nuclear Envelope
.....................................................33
II. Apoptosis
...........................................................33
III. Nucleolus
...........................................................34
IV. Assembly of the Ribosome
..............................................34
Protein Synthesis
зѕ
I. General Features
.....................................................38
II. Transcription
........................................................38
HI. Processing the
RNA
Transcript into mRNA
.................................39
IV Translation
..........................................................39
V. Clinical Considerations
................................................40
ix
χ
CONTENTS
0
Chromosomal
Ш
........................................................45
I. The Biochemistry of Nucleic Acids
.......................................45
II. Levels of
DNA
Packaging
...............................................45
111. Centromere
..........................................................46
IV. Heterochromatin and Euchromatm
.......................................46
V. Studying Human Chromosomes
.........................................47
VI. Staining of Chromosomes
..............................................47
VII.
Chromosome Morphology
..............................................48
θ
О
Numerical Chromosomal Anomalies 53
53
I. Polyploidy
.......................................................... -
II.
Mixoploidy
..........................................................
111. Aneuploidy
..........................................................
IV. Selected Photographs
..................................................
Structural Chromosomal Abnormalities
......................................
58
ero
1.
Deletions
...........................................................
II. Microdeletions
.......................................................
III.
Translocations
.......................................................
IV. Unstable Expanding Repeat Mutations (Dynamic Mutations)
..................
62
V.
Isochromosomes
......................................................
VI. Inversions
...........................................................
VII.
Breakage
............................................................
65
VIII.
Selected Photographs
..................................................
67
О
71
I. General Features
.....................................................
11.
The Replication Process
................................................
III. The Telomere
........................................................
72
IV. Types of
DNA
Damage and
DNA
Repair
...................................72
V. Summary of
DNA
Replication Machinery
.................................. -*
φ
Meiosis and
Genetic
Recombination
77
I. Meiosis
.............................................................77
II.
Oogénesis:
Female
Gametogenesis
........................................79
111. Spermatogenesis: Male Gametogenesis
....................................79
IV. Genetic Recombination
................................................79
Tie
Потав
Unclear Genome
ѕз
1.
General Features
.....................................................83
II.
Protein-Coding Genes
.................................................84
III. RNA-Coding Genes
...................................................85
IV. Epigenetic Control
....................................................87
V. Non-Coding
DNA ....................................................88
φ
The Hnman
Mitoáondrial
Genome
CONTENTS
xi
.92
I. General Features
.....................................................92
II. Protein-Coding Genes
.................................................92
III. RNA-Coding Genes
...................................................92
IV. Other Mitochondrial Proteins
...........................................93
V. Mitochondrial Diseases
................................................93
φ
Control of Gene Expression
95
I. General Features
.....................................................95
II. Mechanism of Gene Expression
..........................................95
III. The Structure of Transcription Factors, Gene Regulatory Proteins,
and Other Trans-Acting Factors
..........................................97
IV. Clinical Considerations
................................................98
V. Other Mechanisms of Gene Expression
....................................99
VI. The lac Operon
......................................................102
VII.
The
trp
Operon
......................................................103
φ
Mutations of the DM Sequence
.106
φ
I. General Features
....................................................106
II. Silent (Synonymous) Mutations
.........................................106
III. Non-Silent (Nonsynonymous) Mutations
.................................106
IV. Loss of Function and Gain of Function Mutations
..........................109
V Other Types of Polymorphisms
.........................................110
Proto-Oncogenes, Oncogenes, and Tnmor-Snppressor Genes ii6
I. Definitions
.........................................................116
II. Designations
........................................................116
III. Proto-Oncogenes and Oncogenes
.......................................116
IV. Tumor Suppressor Genes
..............................................120
V. Molecular Pathology of Colorectal Cancer
................................120
The Cell Cycle
m
I. Phases of the Cell Cycle
...............................................123
II. Control of the Cell Cycle
..............................................123
III. Stages of the
M
(Mitosis) Phase
.........................................125
φ
íoiogy
οι
lancer
129
1.
The Causes of Cancer
.................................................129
II. The Six Superpowers of a Cancer Cell
....................................130
..............132
I. Introduction
........................................................132
II. Human Homeotic Genes
..............................................132
CONTENTS
i
1.
Neutrophils (Polys, Segs, or PMNs)
......................................136
II. Eosinophils
.........................................................136
III. Basophils
..........................................................136
IV. Mast Cells
..........................................................137
V. Monocytes
.........................................................137
VI.
Macrophages (Histiocytes;
Antigen Presenting Cells)
........................137
VII.
Natural Killer CD16+ Cell
............................................138
VIU.
В
Lymphocyte
.......................................................138
IX.
Τ
Lymphocyte
.......................................................139
X. Immune Response to Exogenous Protein Antigens
..........................140
XI. Immune Response to Endogenous Antigens (Intracellular Virus or Bacteria)
.....140
φ
Molecular Biology of the Immune System
.146
I.
Clonal
Selection Theory
...............................................146
II.
В
Lymphocyte
(В
Cell)
................................................146
ΠΙ. Τ
Lymphocyte
(Τ
Cell)
................................................149
IV. Clinical Considerations
...............................................152
V. Disorders of Phagocytic Function
.......................................154
VI. Systemic Autoimmune Disorders
........................................155
VII.
Organ-Specific Autoimmune Disorders
...................................156
DM VirUSeS
............................................................159
1.
Parvoviruses
........................................................159
II. Papovaviruses
.......................................................159
III. Adenoviruses
.......................................................160
IV. Herpesviruses
.......................................................161
V. Poxviruses
.........................................................167
VI. Hepadnaviruses
.....................................................168
φ
Positive ssRNA (+PA) Viruses
.175
I.
Picornaviruses
......................................................175
II. Coronaviruses
......................................................177
III. Retroviruses
........................................................178
IV. Caliciviruses
........................................................180
V. Flaviviruses
........................................................180
VI. Togaviruses
.........................................................180
Negative ssRM(-RM) Viruses
ш>
I. Paramyxoviruses
.................................. 186
II. Orthomyxoviruses
..................... 189
III. Rhabdoviruses
........................ 191
IV. Filoviruses
........................... 191
V. Bunyaviruses
........................... 192
VI. Arenaviruses
.......................... 192
CONTENTS xiii
Double-Stranded
RM
Viruses
.............................................
iqó
І.
Reoviruses .........................................................
196
Molecular Biology Techniques
Identification of Human Disease Genes
.198
.214
I. General Features
....................................................214
II. Identification of a Human Disease Gene Through a Chromosome Abnormality
. . .214
HI. Identification of a Human Disease Gene Through Pure Transcript Mapping
......214
IV. Identification of a Human Disease Gene Through Large Scale
DNA
Sequencing
. . .215
V. Identification of a Human Disease Gene Through Comparison
of Human and Mouse Maps
............................................215
Gene Therapy
...........................................................
216
I. Gene Therapy
......................................................216
II. Ex-Vivo and In-Vivo Gene Therapy
......................................216
III. Integration into Host Cell Chromosomes or as Episomes
.....................217
IV Viral Vectors Used in Gene Therapy
.....................................217
V. Non-Viral Vectors Used in Gene Therapy
.................................218
Understanding the Research Literature
219
I. Introduction
........................................................219
II. Discovery of the Sixpack Protein
........................................219
III. Screening a Mouse Liver cDNA Library
...................................219
IV. Cloning the Human Sbcpacfe-2 Gene
.....................................219
V. Determining the Chromosome Location
..................................220
VI. Cloning the Full-Length Human Sixpacfe-2 Gene
...........................220
VII.
Construction of Gene Knockout Mice
....................................221
VIII.
Regulation of Gene Expression
.........................................221
IX. Transgenic Mice that Overexpress Sixpack-2 Protein
........................223
X. Antisense
RNA
Studies
................................................223
XL Analysis of the Promoter
..............................................223
XII.
Analysis of mRNA and Splicing Mechanism
...............................224
XIII.
Production of
Recombinant
Sixpack-2 Protein
.............................225
Appendix
1:
Functions of Cell Membrane Proteins
..............................226
Appendix
2:
The Genetic Code
..............................................230
Appendix
3:
Amino
Acids
..................................................231
Appendix
4:
Chromosomal Locations of Human Genetic Diseases
..................232
Figure Credits
...........................................................237
Index
..................................................................243
|
| any_adam_object | 1 |
| author | Dudek, Ronald W. 1950- |
| author_GND | (DE-588)135663342 |
| author_facet | Dudek, Ronald W. 1950- |
| author_role | aut |
| author_sort | Dudek, Ronald W. 1950- |
| author_variant | r w d rw rwd |
| building | Verbundindex |
| bvnumber | BV035627136 |
| callnumber-first | Q - Science |
| callnumber-label | QH506 |
| callnumber-raw | QH506 |
| callnumber-search | QH506 |
| callnumber-sort | QH 3506 |
| callnumber-subject | QH - Natural History and Biology |
| classification_rvk | XF 1200 |
| ctrlnum | (OCoLC)71266445 (DE-599)DNB 2006028861 |
| dewey-full | 572.8 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.8 |
| dewey-search | 572.8 |
| dewey-sort | 3572.8 |
| dewey-tens | 570 - Biology |
| discipline | Biologie Medizin |
| edition | 2. ed. |
| format | Book |
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| id | DE-604.BV035627136 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T21:41:54Z |
| institution | BVB |
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| language | English |
| lccn | 2006028861 |
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| physical | XVIII, 254 S. Ill. |
| publishDate | 2006 |
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| record_format | marc |
| series2 | High-yield series |
| spelling | Dudek, Ronald W. 1950- Verfasser (DE-588)135663342 aut High-yield cell and molecular biology Ronald W. Dudek Cell and molecular biology 2. ed. Philadelphia [u.a.] Lippincott, Williams & Wilkins 2006 XVIII, 254 S. Ill. txt rdacontent n rdamedia nc rdacarrier High-yield series Biologie moléculaire - Résumés, programmes, etc Cytologie - Résumés, programmes, etc Pathologie - Résumés, programmes, etc Molecular biology Outlines, syllabi, etc Pathology Outlines, syllabi, etc Cytology Outlines, syllabi, etc Molecular Biology Outlines Cytology Outlines Medizinische Ausbildung (DE-588)4169212-3 gnd rswk-swf Cytologie (DE-588)4070177-3 gnd rswk-swf Molekularbiologie (DE-588)4039983-7 gnd rswk-swf USA (DE-588)4078704-7 gnd rswk-swf (DE-588)4143389-0 Aufgabensammlung gnd-content USA (DE-588)4078704-7 g Medizinische Ausbildung (DE-588)4169212-3 s Molekularbiologie (DE-588)4039983-7 s Cytologie (DE-588)4070177-3 s 1\p DE-604 http://www.loc.gov/catdir/toc/ecip0620/2006028861.html Table of contents only Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017682157&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | Dudek, Ronald W. 1950- High-yield cell and molecular biology Biologie moléculaire - Résumés, programmes, etc Cytologie - Résumés, programmes, etc Pathologie - Résumés, programmes, etc Molecular biology Outlines, syllabi, etc Pathology Outlines, syllabi, etc Cytology Outlines, syllabi, etc Molecular Biology Outlines Cytology Outlines Medizinische Ausbildung (DE-588)4169212-3 gnd Cytologie (DE-588)4070177-3 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| subject_GND | (DE-588)4169212-3 (DE-588)4070177-3 (DE-588)4039983-7 (DE-588)4078704-7 (DE-588)4143389-0 |
| title | High-yield cell and molecular biology |
| title_alt | Cell and molecular biology |
| title_auth | High-yield cell and molecular biology |
| title_exact_search | High-yield cell and molecular biology |
| title_full | High-yield cell and molecular biology Ronald W. Dudek |
| title_fullStr | High-yield cell and molecular biology Ronald W. Dudek |
| title_full_unstemmed | High-yield cell and molecular biology Ronald W. Dudek |
| title_short | High-yield cell and molecular biology |
| title_sort | high yield cell and molecular biology |
| topic | Biologie moléculaire - Résumés, programmes, etc Cytologie - Résumés, programmes, etc Pathologie - Résumés, programmes, etc Molecular biology Outlines, syllabi, etc Pathology Outlines, syllabi, etc Cytology Outlines, syllabi, etc Molecular Biology Outlines Cytology Outlines Medizinische Ausbildung (DE-588)4169212-3 gnd Cytologie (DE-588)4070177-3 gnd Molekularbiologie (DE-588)4039983-7 gnd |
| topic_facet | Biologie moléculaire - Résumés, programmes, etc Cytologie - Résumés, programmes, etc Pathologie - Résumés, programmes, etc Molecular biology Outlines, syllabi, etc Pathology Outlines, syllabi, etc Cytology Outlines, syllabi, etc Molecular Biology Outlines Cytology Outlines Medizinische Ausbildung Cytologie Molekularbiologie USA Aufgabensammlung |
| url | http://www.loc.gov/catdir/toc/ecip0620/2006028861.html http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017682157&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT dudekronaldw highyieldcellandmolecularbiology AT dudekronaldw cellandmolecularbiology |