Mass spectrometry in drug metabolism and pharmacokinetics:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Hoboken, N.J.
John Wiley & Sons
2009
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | XII, 389 S. Ill., graph. Darst. |
| ISBN: | 9780471751588 |
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MARC
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| 245 | 1 | 0 | |a Mass spectrometry in drug metabolism and pharmacokinetics |c ed. by Ragu Ramanathan |
| 264 | 1 | |a Hoboken, N.J. |b John Wiley & Sons |c 2009 | |
| 300 | |a XII, 389 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Drugs |x Metabolism |x Research |x Methodology | |
| 650 | 4 | |a Drugs |x Design | |
| 650 | 4 | |a Mass spectrometry | |
| 650 | 4 | |a Pharmacokinetcs |x Research |x Methodology | |
| 650 | 4 | |a Pharmaceutical Preparations |x metabolism | |
| 650 | 4 | |a Drug Design | |
| 650 | 4 | |a Drug Evaluation, Preclinical |x methods | |
| 650 | 4 | |a Mass Spectrometry |x methods | |
| 650 | 4 | |a Pharmacokinetics | |
| 700 | 1 | |a Ramanathan, Ragu |e Sonstige |4 oth | |
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Record in the Search Index
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|---|---|
| adam_text | Contents
Preface vii
About the Editor ix
Contributors xi
1. Evolving Role of Mass Spectrometry in Drug Discovery
and Development 1
Dil M. Ramanathan and Richard M. LeLacheur
2. Quantitative Bioanalysis in Drug Discovery and Development:
Principles and Applications 87
Ayman El-Kattan, Chris Holliman, and Lucinda H. Cohen
3. Quadrupole, Triple-Quadrupole, and Hybrid Linear Ion Trap
Mass Spectrometers for Metabolite Analysis 123
Elliott B. Jones
4. Applications of Quadrupole Time-of-Flight Mass Spectrometry
in Reactive Metabolite Screening 159
Jose M. Castro-Perez
5. Changing Role of FTMS in Drug Metabolism 191
Petia A. Shipkova, Jonathan L. Josephs, and Mark Sanders
6. High-Resolution LC-MS-Based Mass Defect Filter Approach:
Basic Concept and Application in Metabolite Detection 223
Haiying Zhang, Donglu Zhang, Mingshe Zhu, and Kenneth L. Ray
v
VI CONTENTS
7. Applications of High-Sensitivity Mass Spectrometry and
Radioactivity Detection Techniques in Drug Metabolism Studies 253
Wing W. Lam, Cho-Ming Loi, Angus Nedderman, and Don Walker
8. Online Electrochemical-LC-MS Techniques for Profiling and
Characterizing Metabolites and Degradants 275
Paul H. Gamache, David F. Meyer, Michael C. Granger, and Ian N. Acworth
9. LC-MS Methods with Hydrogen/Deuterium Exchange
for Identification of Hydroxylamine, JV-Oxide, and
Hydroxylated Analogs of Desloratadine 295
Natalia A. Penner, Joanna Zgoda-Pols, Ragu Ramanathan,
Swapan K. Chowdhury, and Kevin B. Alton
10. Turbulent-Flow LC-MS: Applications for Accelerating
Pharmacokinetic Profiling and Metabolite Identification 311
Joseph L. Herman and Joseph M. Di Bussolo
11. Desorption Ionization Techniques for Quantitative Analysis
of Drug Molecules 341
Jason S. Gobey, John Janiszewski, and Mark J. Cole
12. MALDI Imaging Mass Spectrometry for Direct Tissue Analysis
of Pharmaceuticals 359
Yunsheng Hsieh and Walter A. Korfmacher
Index 383
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| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615/.7 |
| dewey-search | 615/.7 |
| dewey-sort | 3615 17 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
| format | Book |
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| id | DE-604.BV035456061 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T21:35:40Z |
| institution | BVB |
| isbn | 9780471751588 |
| language | English |
| lccn | 2008021424 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-017376000 |
| oclc_num | 174129887 |
| open_access_boolean | |
| owner | DE-19 DE-BY-UBM |
| owner_facet | DE-19 DE-BY-UBM |
| physical | XII, 389 S. Ill., graph. Darst. |
| publishDate | 2009 |
| publishDateSearch | 2009 |
| publishDateSort | 2009 |
| publisher | John Wiley & Sons |
| record_format | marc |
| spelling | Mass spectrometry in drug metabolism and pharmacokinetics ed. by Ragu Ramanathan Hoboken, N.J. John Wiley & Sons 2009 XII, 389 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index Drugs Metabolism Research Methodology Drugs Design Mass spectrometry Pharmacokinetcs Research Methodology Pharmaceutical Preparations metabolism Drug Design Drug Evaluation, Preclinical methods Mass Spectrometry methods Pharmacokinetics Ramanathan, Ragu Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017376000&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Mass spectrometry in drug metabolism and pharmacokinetics Drugs Metabolism Research Methodology Drugs Design Mass spectrometry Pharmacokinetcs Research Methodology Pharmaceutical Preparations metabolism Drug Design Drug Evaluation, Preclinical methods Mass Spectrometry methods Pharmacokinetics |
| title | Mass spectrometry in drug metabolism and pharmacokinetics |
| title_auth | Mass spectrometry in drug metabolism and pharmacokinetics |
| title_exact_search | Mass spectrometry in drug metabolism and pharmacokinetics |
| title_full | Mass spectrometry in drug metabolism and pharmacokinetics ed. by Ragu Ramanathan |
| title_fullStr | Mass spectrometry in drug metabolism and pharmacokinetics ed. by Ragu Ramanathan |
| title_full_unstemmed | Mass spectrometry in drug metabolism and pharmacokinetics ed. by Ragu Ramanathan |
| title_short | Mass spectrometry in drug metabolism and pharmacokinetics |
| title_sort | mass spectrometry in drug metabolism and pharmacokinetics |
| topic | Drugs Metabolism Research Methodology Drugs Design Mass spectrometry Pharmacokinetcs Research Methodology Pharmaceutical Preparations metabolism Drug Design Drug Evaluation, Preclinical methods Mass Spectrometry methods Pharmacokinetics |
| topic_facet | Drugs Metabolism Research Methodology Drugs Design Mass spectrometry Pharmacokinetcs Research Methodology Pharmaceutical Preparations metabolism Drug Design Drug Evaluation, Preclinical methods Mass Spectrometry methods Pharmacokinetics |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017376000&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT ramanathanragu massspectrometryindrugmetabolismandpharmacokinetics |