Drug addiction: from basic research to therapy
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer
2008
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XXIII, 782 S. Ill., graph. Darst. |
| ISBN: | 0387766774 9780387766775 |
Internformat
MARC
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| 245 | 1 | 0 | |a Drug addiction |b from basic research to therapy |c Rao S. Rapaka ..., ed. |
| 264 | 1 | |a New York, NY |b Springer |c 2008 | |
| 300 | |a XXIII, 782 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Designer Drugs |x pharmacokinetics | |
| 650 | 4 | |a Designer Drugs |x pharmacology | |
| 650 | 4 | |a Drug Design | |
| 650 | 4 | |a Drug addiction | |
| 650 | 4 | |a Drug addiction |x Treatment | |
| 650 | 4 | |a Substance-Related Disorders |x physiopathology | |
| 650 | 4 | |a Substance-Related Disorders |x therapy | |
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| 700 | 1 | |a Rapaka, Rao S. |e Sonstige |4 oth | |
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Datensatz im Suchindex
| _version_ | 1804138855423541248 |
|---|---|
| adam_text | Contents
I
General
Topics
1 DARPP-32
Mediates the Actions of Multiple Drugs of Abuse
......... 3
Per
Svenningsson,
Angus C. Nairn, and Paul Greengard
2
Drug Discovery From Natural Sources
........................... 17
Young-Won Chin, Marcy J. Balunas,
Нее
Byung
Chai,
and
A. Douglas Kinghorn
3
Computational Methods in Drug Design: Modeling
G
Protein-Coupled Receptor Monomers, Dimers, and
Oligomers
....... 41
Patricia H.
Reggio
4
Symbiotic Relationship of Pharmacogenetics and Drugs
of Abuse
..................................................... 69
Joni L.
Rutter
5
Monoclonal Antibody Form and Function: Manufacturing
the Right Antibodies for Treating Drug Abuse
..................... 87
Eric Peterson, S. Michael Owens, and Ralph L. Henry
6
Cocaine- and Amphetamine-Regulated Transcript Peptides
Play a Role in Drug Abuse and Are Potential
Therapeutic Targets
.......................................... 101
Michael J.
Kuhar,
Jason
N.
Jaworski, George W. Hubert,
Kelly B. Philpot, and
Geraldina
Domínguez
7
RNAi-Directed Inhibition of DC-SIGN by Dendritic Cells:
Prospects for HIV-1 Therapy
.................................. 113
Madhavan P.N. Nair, Jessica L. Reynolds, Supriya D. Mahajan,
Stanley A. Schwartz, Ravikumar Aalinkeel, B. Bindukumar,
and Don Sykes
v¡jj
Contents
8
Viewing Chemokines as a Third Major System of
Communication in the Brain
................................. 127
Martin W.
Adler,
Ellen B.
Geller, Xiaohong
Chen,
and Thomas J. Rogers
9
Targeting the PDZ Domains of Molecular Scaffolds
of
Transmembrane Ion
Channels
.............................. 139
Andrea Piserchio, Mark
Spalier,
and Dale
F. Mierke
10 Neuronal Nicotinic Acetylcholine
Receptor Expression
and Function on
Nonneuronal
Cells
........................... 149
Lorise C. Gahring and Scott W. Rogers
11 Transporters
&
Stimulants
&
Hallucinogens
11
Role of Monoamine Transporters in Mediating
Psychostimulant
Effects
..................................... 169
Evan L. Riddle, Annette E.
Fleckenstein,
and Glen R. Hanson
12
Development of the Dopamine Transporter Selective RTI-336
as a Pharmacotherapy for Cocaine Abuse
...................... 179
F. Ivy Carroll, James L. Howard, Leonard L. Howell,
Barbara S. Fox, and Michael J.
Kuhar
13
Serotonin Transporters: Implications for Antidepressant
Drug Development
.......................................... 193
Kellie
J. White, Crystal C. Walline, and Eric L. Barker
14
Recent Advances for the Treatment of Cocaine Abuse:
Central Nervous System Immunopharmacotherapy
.............. 217
Tobin
J. Dickerson and Kim D.
Janda
15
к
Opioids as Potential Treatments for Stimulant Dependence
...... 231
Thomas E. Prisinzano, Kevin Tidgewell, and Wayne W. Harding
16
Regulation of Monoamine Transporters: Influence of
Psychostimulants
and Therapeutic Antidepressants
.............. 247
Lankupaîle
D.
Jayanthi and Sammanda Ramamoorthy
17
Hallucinogen Actions on 5-HT Receptors Reveal Distinct
Mechanisms of Activation and Signaling by
G
Protein-Coupled Receptors
................................. 265
Hare!
Weinstein
Contents ix
18
Recognition of
Psychostimulants, Antidepressants,
and Other
Inhibitors of Synaptic
Neurotransmitter
Uptake by the Plasma
Membrane Monoamine Transporters
.......................... 287
Christopher
K. Surratt,
Okechukwu T. Ukairo, and
Suneetha Ramanuj
apuram
19
Dual Dopamine/Serotonin Releasers as Potential Medications
for Stimulant and Alcohol Addictions
.......................... 311
Richard
B. Rothman,
Bruce
Е. В
lough, and Michael H.
Baumann
20
Receptors of Mammalian Trace Amines
........................ 327
Anita H.
Lewin
III Drug Design: Nicotine, Opioids and Related Ligands
21
The Role of Crystallography in Drug Design
.................... 343
Jeffrey R.
Deschamps
22
Opioid Peptide-Derived Analgesics
............................ 357
Peter W. Schiller
23
Opioid Ligands with Mixed
μ/δ
Opioid Receptor Interactions:
An Emerging Approach to Novel Analgesics
.................... 367
Subramaniam Ananthan
24
Small-Molecule Agonists and Antagonists of the Opioid
Receptor-Like Receptor
(ORLI,
NOP): Ligand-Based
Analysis
of Structural Factors Influencing Intrinsic Activity at
NOP
....... 381
Nurulain Zaveri, Faming Jiang,
Cris
Olsen, Willma Polgar,
and Lawrence Toll
25
Kappa Opioid Antagonists: Past Successes
and Future Prospects
........................................ 395
Matthew D. Metcalf and Andrew Coop
26
In Vitro and Direct In Vivo Testing of Mixture-Based
Combinatorial Libraries for the Identification of Highly Active
and Specific Opiate Ligands
.................................. 433
Richard A. Houghten. Colette T. Dooley, and Jon
R. Appel
27
Current Status of
Immunologie
Approaches to Treating Tobacco
Dependence: Vaccines and Nicotine-Specific Antibodies
........... 455
Mark G. LeSage. Daniel E.
Keyler,
and Paul R. Pentel
x
Contents
28
New Paradigms and Tools in Drug Design
for Pain and Addiction
...................................... 477
Victor J. Hraby, Frank Porreca, Henry I. Yamamura, Gordon Tollin,
Richard S. Agnes, Yeon Sun Lee, Minying
Cai,
Isabel
Alves,
Scott Cowell,
Eva Varga,
Peg Davis,
Zdzisław
Salamon,
William Roeske, Todd Vanderah, and Josephine Lai
IV Opioids: General
29
Neuropeptide-Processing Enzymes: Applications
for Drug Discovery
.......................................... 497
Lloyd D. Flicker
30
CNS Drug Delivery: Opioid Peptides
and the Blood-Brain Barrier
................................. 511
Ken A. Witt and Thomas P. Davis
31
Cell-Permeable, Mitochondrial-Targeted,
Peptide
Antioxidante___
535
Hazel
H.
Szeto
32
Targeting Opioid Receptor Heterodimers: Strategies
for Screening and Drug Development
.......................... 547
Achia
Gupta,
Fabien M. Décaillot,
and Lakshmi A. Devi
33
Homology Modeling of Opioid Receptor-Ligand Complexes
Using Experimental Constraints
.............................. 559
Irina
D.
Pogozheva,
Magdalena
J.
Przydział, and Henry I.
Mosberg
34
Molecular Recognition of Opioid Receptor Ligands
.............. 585
Brian E. Kane,
Bengt Svensson,
and David M. Ferguson
35
Role of Morphine s Metabolites in Analgesia: Concepts
and Controversies
.......................................... 609
Erica Wittwer and Steven E. Kern
36
Mu Opioid Receptor Regulation and Opiate Responsiveness
....... 617
Kirsten
M.
Raehal and Laura
M. Bohn
37
Agmatine: Biological Role and Therapeutic Potentials
in Morphine Analgesia and Dependence
........................ 625
Soundar Regunathan
Contents xi
V Cannabinoid
38
The Therapeutic Potential of Drugs that Target
Cannabinoid
Receptors or Modulate the Tissue Levels or Actions
of Endocannabinoids
........................................ 637
Roger G. Pertwee
39
Further Advances in the Synthesis of Endocannabinoid-Related
Ligands
................................................... 687
Anu
Mahadevan and Raj K. Razdan
40
Ajulemic Acid (IP-751): Synthesis, Proof of Principle,
Toxicity
Studies, and Clinical Trials
........................... 697
Sumner Burstein
41
Conformational Characteristics of the Interaction of SR141716A
with the CB1 Cannabinoid Receptor as Determined Through
the Use of Conformationally Constrained Analogs
............... 707
Brian F. Thomas, Yanan Zhang, Marcus Brackeen, Kevin M. Page,
S. Wayne Mascarella, and Herbert H. Seltzman
42
Activation of G-Proteins in Brain by Endogenous
and Exogenous Cannabinoids
................................. 719
Steven R. Childers
43
Ž-Arachidonoylglycerol (2-AG)
Membrane Transport:
History and Outlook
........................................ 731
Anita Hermann, Martin Kaczocha, and Dale G.
Deutsch
44
Endocannabinoid Mechanisms of Pain Modulation
.............. 737
Andrea G. Hohmann and Richard L. Suplita, II
Index
......................................................... 765
|
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| language | English |
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| spelling | Drug addiction from basic research to therapy Rao S. Rapaka ..., ed. New York, NY Springer 2008 XXIII, 782 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Designer Drugs pharmacokinetics Designer Drugs pharmacology Drug Design Drug addiction Drug addiction Treatment Substance-Related Disorders physiopathology Substance-Related Disorders therapy Drogenabhängigkeit (DE-588)4138597-4 gnd rswk-swf Drogenabhängigkeit (DE-588)4138597-4 s DE-604 Rapaka, Rao S. Sonstige oth Erscheint auch als Online-Ausgabe 978-0-387-76678-2 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017335867&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Drug addiction from basic research to therapy Designer Drugs pharmacokinetics Designer Drugs pharmacology Drug Design Drug addiction Drug addiction Treatment Substance-Related Disorders physiopathology Substance-Related Disorders therapy Drogenabhängigkeit (DE-588)4138597-4 gnd |
| subject_GND | (DE-588)4138597-4 |
| title | Drug addiction from basic research to therapy |
| title_auth | Drug addiction from basic research to therapy |
| title_exact_search | Drug addiction from basic research to therapy |
| title_full | Drug addiction from basic research to therapy Rao S. Rapaka ..., ed. |
| title_fullStr | Drug addiction from basic research to therapy Rao S. Rapaka ..., ed. |
| title_full_unstemmed | Drug addiction from basic research to therapy Rao S. Rapaka ..., ed. |
| title_short | Drug addiction |
| title_sort | drug addiction from basic research to therapy |
| title_sub | from basic research to therapy |
| topic | Designer Drugs pharmacokinetics Designer Drugs pharmacology Drug Design Drug addiction Drug addiction Treatment Substance-Related Disorders physiopathology Substance-Related Disorders therapy Drogenabhängigkeit (DE-588)4138597-4 gnd |
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