EGFR signaling networks in cancer therapy:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Humana Press
2008
|
| Schriftenreihe: | Cancer drug discovery and development
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XI, 393 S. Ill., graph. Darst. |
| ISBN: | 9781588299482 9781597453561 |
Internformat
MARC
| LEADER | 00000nam a2200000 c 4500 | ||
|---|---|---|---|
| 001 | BV035394761 | ||
| 003 | DE-604 | ||
| 005 | 20090508 | ||
| 007 | t | ||
| 008 | 090326s2008 ad|| |||| 00||| eng d | ||
| 020 | |a 9781588299482 |9 978-1-58829-948-2 | ||
| 020 | |a 9781597453561 |9 978-1-59745-356-1 | ||
| 035 | |a (OCoLC)293326620 | ||
| 035 | |a (DE-599)BVBBV035394761 | ||
| 040 | |a DE-604 |b ger |e rakwb | ||
| 041 | 0 | |a eng | |
| 049 | |a DE-355 | ||
| 050 | 0 | |a RC270.8 | |
| 082 | 0 | |a 616.99406 |2 22 | |
| 084 | |a XH 2550 |0 (DE-625)152881:13129 |2 rvk | ||
| 245 | 1 | 0 | |a EGFR signaling networks in cancer therapy |c ed. by John D. Haley ... |
| 264 | 1 | |a New York, NY |b Humana Press |c 2008 | |
| 300 | |a XI, 393 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Cancer drug discovery and development | |
| 650 | 4 | |a Cancer |x Chemotherapy | |
| 650 | 4 | |a Cancer |x Treatment | |
| 650 | 4 | |a Neoplasms |x drug therapy | |
| 650 | 4 | |a Neoplasms |x metabolism | |
| 650 | 4 | |a Receptor, Epidermal Growth Factor |x antagonists & inhibitors | |
| 650 | 4 | |a Receptor, Epidermal Growth Factor |x metabolism | |
| 650 | 4 | |a Signal Transduction |x drug effects | |
| 650 | 0 | 7 | |a Krebs |g Medizin |0 (DE-588)4073781-0 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Epidermaler Wachstumsfaktor-Rezeptor |0 (DE-588)4271161-7 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Krebs |g Medizin |0 (DE-588)4073781-0 |D s |
| 689 | 0 | 1 | |a Epidermaler Wachstumsfaktor-Rezeptor |0 (DE-588)4271161-7 |D s |
| 689 | 0 | |C b |5 DE-604 | |
| 700 | 1 | |a Haley, John D. |e Sonstige |4 oth | |
| 856 | 4 | 2 | |m Digitalisierung UB Regensburg |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017315501&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-017315501 | ||
Datensatz im Suchindex
| _version_ | 1804138819394469888 |
|---|---|
| adam_text | Table of Contents
Preface
................................................................................................................
v
Contributors
........................................................................................................ ix
Section I: EGFR Signaling Networks
1
EGF Receptor Family Extracellular Domain Structures
and Functions
.................................................................................................. 3
Antony W. Burgess and Thomas P.J. Garrett
2
EGFR Family Heterodimers in Cancer Pathogenesis
and Treatment
................................................................................................. 15
Howard M. Stern
3
Structure-function of EGFR Kinase Domain and Its Inhibitors
........................... 31
Charles
Eigenbrot
4
Internalization and Degradation of the EGF Receptor
.......................................... 47
Alexander Sorkin
5
Differential Dependence of EGFR and ErbB2 on the Molecular
Chaperone Hsp90
.......................................................................................... 63
WanpingXu,
Len
Neckers
6
Activation of STATs
3
and
5
Through the EGFR
Signaling Axis
............................................................................................... 73
Priya Koppikar and Jennifer Rubin
Grandis
7
The Intersection of EGFR and the
Ras
Signaling Pathway
.................................. 89
Marie Wislez and Jonathan
M. Kurie
8
Phosphoinositide 3-Kinase Enzymes as Downstream Targets
of the EGF Receptor
....................................................................................... 97
Jan Domin
9
Convergence of EGF Receptor and Src Family Signaling
Networks in Cancer
........................................................................................ 119
Jessica E. Pritchard, Allison B.
Jabłoński,
and Sarah J. Parsons
10
A Molecular Crosstalk between E-cadherin and EGFR
Signaling Networks
........................................................................................ 139
Julie Gavard and J. Silvio Gutkind
11
Crosstalk Between Insulin-like Growth Factor (IGF) and Epidermal
Growth Factor (EGF) Receptors
..................................................................... 155
Marc A. Becker and Douglas Yee
12
Negative Regulation of Signaling by the EGFR Family
....................................... 169
Kermit
L·
Carraway,
IH,
Idly Yen, Ellen
Ingolla,
and Colleen Sweeney
13
Nuclear ErbB Receptors: Pathways and Functions
............................................... 187
Hong-
Jun
Luto
and Graham Carpenter
VII
Contents
14
Temporal Dynamics of EGF Receptor
Signaling by Quantitative
Proteomics
...................................................................................................... 199
Blagoy Blagoev,
Mna Kratchmarova,
Jesper V.
Olsen
and Matthias
Mann
15
Computational and Mathematical Modeling of the EGF
Receptor System
............................................................................................. 209
Colin G. Johnson, Emmet McJntyre, and William Gullick
Section II: EGFR in Tumorigenesis and EGFR Tyrosine Kinase
Inhibitors in Cancer Therapy
16
Expression and Prognostic Significance of the EGFR
in Solid Tumors
.............................................................................................. 221
Nicola
Normanno, Caterina
Bianco,
Antonella De
Luca, Luigi Strizzi,
Marianna
Gallo, Mario Mancino and David S.
Salomon
17
Signaling by the EGF Receptor in Human Cancers: Accentuate
the Positive, Eliminate the Negative
............................................................... 235
Haley L. Bennett, Tilman
Brummer,
Paul Timpson, Kate I. Patterson
and Roger J. Daly
18
EGFR Signaling in Invasion, Angiogenesis
and Metastasis
................................................................................................ 257
Carol Box, Joanna Peak,
Susanne
Rogers, and Suzanne Eccles
19
Constitutive Activation of Truncated EGF Receptors
in Glioblastoma
.............................................................................................. 277
Carol J. Wikstrand and Darell D.
Bigner
20
EGFR Mutations, Other Molecular Alterations Related to Sensitivity
to EGFR Inhibitors, and Molecular Testing for EGFR-Targeted
Therapies in Non-Small Cell Lung Cancer
.................................................... 293
David A.
Eberhard
21
Crosstalk Between COX-2 and EGFR: A Potential Therapeutic
Opportunity
..................................................................................................... 337
Andrew J. Dannenberg and Kotha Subbaramaiah
22
Cellular Sensitivity to EGF Receptor Inhibitors
................................................... 353
Stuart Thomson, John D. Haley and Robert Yauch
23
Utilizing Combinations of Molecular Targeted Agents to Sensitize
Tumor Cells to EGFR Inhibitors
.................................................................... 369
Elizabeth Buck, Alexandra Eyzaguirre, and Kenneth K. Iwata
|
| any_adam_object | 1 |
| building | Verbundindex |
| bvnumber | BV035394761 |
| callnumber-first | R - Medicine |
| callnumber-label | RC270 |
| callnumber-raw | RC270.8 |
| callnumber-search | RC270.8 |
| callnumber-sort | RC 3270.8 |
| callnumber-subject | RC - Internal Medicine |
| classification_rvk | XH 2550 |
| ctrlnum | (OCoLC)293326620 (DE-599)BVBBV035394761 |
| dewey-full | 616.99406 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 616 - Diseases |
| dewey-raw | 616.99406 |
| dewey-search | 616.99406 |
| dewey-sort | 3616.99406 |
| dewey-tens | 610 - Medicine and health |
| discipline | Medizin |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01842nam a2200469 c 4500</leader><controlfield tag="001">BV035394761</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20090508 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">090326s2008 ad|| |||| 00||| eng d</controlfield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781588299482</subfield><subfield code="9">978-1-58829-948-2</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9781597453561</subfield><subfield code="9">978-1-59745-356-1</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)293326620</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV035394761</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakwb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">RC270.8</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">616.99406</subfield><subfield code="2">22</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">XH 2550</subfield><subfield code="0">(DE-625)152881:13129</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">EGFR signaling networks in cancer therapy</subfield><subfield code="c">ed. by John D. Haley ...</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">New York, NY</subfield><subfield code="b">Humana Press</subfield><subfield code="c">2008</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XI, 393 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="490" ind1="0" ind2=" "><subfield code="a">Cancer drug discovery and development</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cancer</subfield><subfield code="x">Chemotherapy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Cancer</subfield><subfield code="x">Treatment</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neoplasms</subfield><subfield code="x">drug therapy</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Neoplasms</subfield><subfield code="x">metabolism</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Receptor, Epidermal Growth Factor</subfield><subfield code="x">antagonists & inhibitors</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Receptor, Epidermal Growth Factor</subfield><subfield code="x">metabolism</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Signal Transduction</subfield><subfield code="x">drug effects</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Krebs</subfield><subfield code="g">Medizin</subfield><subfield code="0">(DE-588)4073781-0</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Epidermaler Wachstumsfaktor-Rezeptor</subfield><subfield code="0">(DE-588)4271161-7</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Krebs</subfield><subfield code="g">Medizin</subfield><subfield code="0">(DE-588)4073781-0</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Epidermaler Wachstumsfaktor-Rezeptor</subfield><subfield code="0">(DE-588)4271161-7</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="C">b</subfield><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Haley, John D.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Digitalisierung UB Regensburg</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017315501&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-017315501</subfield></datafield></record></collection> |
| id | DE-604.BV035394761 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T21:34:15Z |
| institution | BVB |
| isbn | 9781588299482 9781597453561 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-017315501 |
| oclc_num | 293326620 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR |
| owner_facet | DE-355 DE-BY-UBR |
| physical | XI, 393 S. Ill., graph. Darst. |
| publishDate | 2008 |
| publishDateSearch | 2008 |
| publishDateSort | 2008 |
| publisher | Humana Press |
| record_format | marc |
| series2 | Cancer drug discovery and development |
| spelling | EGFR signaling networks in cancer therapy ed. by John D. Haley ... New York, NY Humana Press 2008 XI, 393 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Cancer drug discovery and development Cancer Chemotherapy Cancer Treatment Neoplasms drug therapy Neoplasms metabolism Receptor, Epidermal Growth Factor antagonists & inhibitors Receptor, Epidermal Growth Factor metabolism Signal Transduction drug effects Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Epidermaler Wachstumsfaktor-Rezeptor (DE-588)4271161-7 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 s Epidermaler Wachstumsfaktor-Rezeptor (DE-588)4271161-7 s b DE-604 Haley, John D. Sonstige oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017315501&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | EGFR signaling networks in cancer therapy Cancer Chemotherapy Cancer Treatment Neoplasms drug therapy Neoplasms metabolism Receptor, Epidermal Growth Factor antagonists & inhibitors Receptor, Epidermal Growth Factor metabolism Signal Transduction drug effects Krebs Medizin (DE-588)4073781-0 gnd Epidermaler Wachstumsfaktor-Rezeptor (DE-588)4271161-7 gnd |
| subject_GND | (DE-588)4073781-0 (DE-588)4271161-7 |
| title | EGFR signaling networks in cancer therapy |
| title_auth | EGFR signaling networks in cancer therapy |
| title_exact_search | EGFR signaling networks in cancer therapy |
| title_full | EGFR signaling networks in cancer therapy ed. by John D. Haley ... |
| title_fullStr | EGFR signaling networks in cancer therapy ed. by John D. Haley ... |
| title_full_unstemmed | EGFR signaling networks in cancer therapy ed. by John D. Haley ... |
| title_short | EGFR signaling networks in cancer therapy |
| title_sort | egfr signaling networks in cancer therapy |
| topic | Cancer Chemotherapy Cancer Treatment Neoplasms drug therapy Neoplasms metabolism Receptor, Epidermal Growth Factor antagonists & inhibitors Receptor, Epidermal Growth Factor metabolism Signal Transduction drug effects Krebs Medizin (DE-588)4073781-0 gnd Epidermaler Wachstumsfaktor-Rezeptor (DE-588)4271161-7 gnd |
| topic_facet | Cancer Chemotherapy Cancer Treatment Neoplasms drug therapy Neoplasms metabolism Receptor, Epidermal Growth Factor antagonists & inhibitors Receptor, Epidermal Growth Factor metabolism Signal Transduction drug effects Krebs Medizin Epidermaler Wachstumsfaktor-Rezeptor |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=017315501&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT haleyjohnd egfrsignalingnetworksincancertherapy |