Molecular recognition and polymers: control of polymer structure and self-assembly
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| Language: | English |
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Hoboken, NJ
Wiley
2008
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| Online Access: | Publisher description Table of contents only Inhaltsverzeichnis |
| Item Description: | Ill., graph. Darst. |
| Physical Description: | XLV, 436 S. |
| ISBN: | 9780470277386 |
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| 245 | 1 | 0 | |a Molecular recognition and polymers |b control of polymer structure and self-assembly |c ed. by Vincent M. Rotello ; S. Thayumanavan |
| 264 | 1 | |a Hoboken, NJ |b Wiley |c 2008 | |
| 300 | |a XLV, 436 S. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Ill., graph. Darst. | ||
| 650 | 4 | |a Biomimetic polymers | |
| 650 | 4 | |a Molecular recognition | |
| 650 | 4 | |a Supramolecular chemistry | |
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| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Rotello, Vincent M. |e Sonstige |4 oth | |
| 700 | 1 | |a Thayumanavan, Sankaran |e Sonstige |4 oth | |
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| adam_text | CONTENTS
Preface xvii
Acknowledgments xix
List of Contributors xxi
List of Figures xxv
List of Tables xlvii
Editor Biographies xlix
PART I FUNDAMENTALS OF SUPRAMOLECULAR
POLYMERS 1
1. A BRIEF INTRODUCTION TO SUPRAMOLECULAR
CHEMISTRY IN A POLYMER CONTEXT 3
Raymond J. Thibault and Vincent M. Rotello
l. 1. Introduction and Background / 3
1.2. Main-Chain Versus Side-Chain Supramolecular Polymers / 4
References / 6
vii
VÜi CONTENTS
2. MOLECULAR RECOGNITION USING AMPHIPHILIC
MACROMOLECULES 9
Malar A. Azagarsamy, K. Krishnamoorthy, and S. Thayumanavan
2.1. Introduction / 9
2.2. Amphiphilic Block Copolymers / 11
2.2.1. Nonspecific Interactions / 13
2.2.2. Specific Interactions / 17
2.3. Amphiphilic Homopolymers / 22
2.3.1. Container Properties / 24
2.3.2. Recognition of Protein Surfaces / 25
2.3.3. Protein Sensing / 26
2.3.4. Recognition and Detection of Peptides / 28
2.4. Amphiphilic Dendrimers / 29
2.5. Conclusions / 29
Acknowledgment / 30
References / 30
3. SUPRAMOLECULAR CONTROL OF MECHANICAL
PROPERTIES IN SINGLE MOLECULES, INTERFACES,
AND MACROSCOPIC MATERIALS 37
David M. Loveless, Farrell R. Kersey, and Stephen L. Craig
3.1. Introduction and Background / 37
3.2. Mechanical Properties of Linear SPs / 40
3.3. Mechanical Properties of SP Networks / 46
3.4. Mechanical Properties in SPs at Interfaces / 50
3.5. Mechanical Forces and Supramolecular Interactions / 55
3.6. Conclusions / 57
References / 58
PART II POLYMER FORMATION AND SELF-ASSEMBLY 63
4. HYDROGEN BOND FUNCTIONALIZED BLOCK
COPOLYMERS AND TELECHELIC OLIGOMERS 65
Brian D. Mather and Timothy E. Long
4.1. Scientific Rationale and Perspective / 65
4.2. Hydrogen Bonding Interactions in Macromolecular Design / 66
4.2.1. Fundamentals of Hydrogen Bonding / 66
CONTENTS iX
4.2.2. Performance Advantages of Hydrogen Bond
Containing Polymers / 69
4.3. Hydrogen Bond Containing Block Copolymers / 73
4.3.1. Block Copolymers Involving Single Hydrogen Bonding
Groups / 74
4.3.2. Nucleobase Containing Hydrogen Bonding Block
Copolymers / 76
4.3.3. Block Copolymers Containing DNA Oligonucleotides / 80
4.3.4. Block Copolymers Containing Other Hydrogen Bonding
Arrays / 83
4.3.5. Order-Disorder Transitions (ODTs) in Hydrogen Bonding
Block Copolymers / 84
4.4. Telechelic Hydrogen Bond Functional Polymers / 85
4.5. Combining Hydrogen Bonding with Other Noncovalent Interactions / 90
4.6. Reversible Attachment of Guest Molecules via Hydrogen Bonding / 91
4.7. Conclusions and Summary / 93
References / 94
5. NONCOVALENT SIDE CHAIN MODIFICATION 103
Kamlesh P. Nair and Marcus Weck
5.1. Introduction / 103
5.1.1. Supramolecular Polymers / 104
5.2. Strategies Toward Noncovalent Side Chain Functionalization of
Polymeric Scaffolds / 105
5.2.1. Side Chain Functionalization Using Hydrogen Bonding / 105
5.2.2. Side Chain Functionalization Using Metal Coordination / 108
5.2.3. Side Chain Functionalization Using Coulombic Interactions / 109
5.3. Noncovalent Multifunctionalization of the Side Chains of Polymeric
Scaffolds / 111
5.3.1. Combination of Hydrogen Bonding and Metal
Coordination Interactions / 112
5.3.2. Combination of Hydrogen Bonding and Coulombic Charges / 114
5.3.3. Multiple Hydrogen Bonding Interactions: Self-Sorting on
Polymers / 115
5.3.4. Terpolymer Functionalization Strategies: Combing
Hydrogen Bonding, Metal Coordination, and
Pseudorotaxane Formation / 116
5.4. Applications of Noncovalently Functionalized Side Chain
Copolymers / 118
5.4.1. Seif-Assembled Functional Materials / 118
X CONTENTS
5.4.2. Network Formation Using Side Chain Supramolecular
Polymers / 120
5.5. Conclusions and Outlook / 131
Acknowledgments / 132
References / 132
6. POLYMER-MEDIATED ASSEMBLY OF NANOPARTICLES
USING ENGINEERED INTERACTIONS 137
Hung-Ting Chen, Yuval Ofir, and Vincent M. Rotello
6.1. Introduction / 137
6.2. Design of Nanoparticles and Polymers / 138
6.3. Seif-Assembly of Polymer-Particle Nanocomposites / 139
6.3.1. Control of Interparticle Spacing / 139
6.3.2. Self-Assembly of Nanoparticles Mediated by Polymers on the
Planar Substrates / 142
6.3.3. Control of 3-D Hierarchical Organization in the Solution / 148
6.4. Conclusions and Outlook / 151
References / 151
7. METALLOSUPRAMOLECULAR POLYMERS, NETWORKS,
AND GELS 157
Blayne M. McKenzie and Stuart J. Rowan
7.1. Introduction / 157
7.2. Metal-Ligand Binding Motifs / 159
7.3. Linear and Macrocyclic Main Chain MSPs / 161
7.4. Metallosupramolecular Networks and Gels / 169
7.5. Conclusion and Outlook / 175
References / 175
8. POLYMERIC CAPSULES: CATALYSIS AND
DRUG DELIVERY 179
Brian P. Mason, Jeremy L. Steinbacher, and D. Tyler McQuade
8.1. Introduction / 179
8.2. Methods of Encapsulation / 180
8.2.1. Coacervation / 182
8.2.2. Interfacial Polymerization / 182
8.2.3. Colloidosomes / 183
8.2.4. Colloidal Templating / 184
8.2.5. Vesicles / 185
CONTENTS Xi
8.3. Catalyst Encapsulation / 186
8.3.1. General / 186
8.3.2. Encapsulated Catalysts / 188
8.4. Drug Delivery with Microcapsules / 191
8.4.1. Homogeneous Particles / 191
8.4.2. Interfacial Polymerization / 192
8.4.3. Colloidal Templates / 192
8.4.4. Vesicles / 193
8.5. Conclusion / 197
References / 197
9. SEQUENCE-SPECIFIC HYDROGEN BONDED
UNITS FOR DIRECTED ASSOCIATION,
ASSEMBLY, AND LIGATION 207
Bing Gong
9.1. Introduction / 207
9.2. General Design: Information-Storing Molecular Duplexes
Based on the Recombination of H Bond Donors
and Acceptors / 208
9.3. Quadruply H Bonded Duplexes with Sequence-Independent
Stability / 209
9.4. Tuning Binding Strength by Varying the Number of InterStrand
H Bonds / 212
9.5. Probing Sequence Specificity / 213
9.6. Unexpected Discovery: Duplexes Containing
Folded Strands / 216
9.7. Directed Assembly: Formation of /3-Sheets and Supramolecular Block
Copolymers / 219
9.7.1. Directed Assembly: Templated Formation of Two-Stranded
/3-Sheets / 219
9.7.2. Supramolecular Block Copolymers / 220
9.8. Integrating Noncovalent and Covalent Interactions:
Directed Olefin Metathesis and Disulfide Bond
Formation / 223
9.8.1. Templated Olefin Cross-Metathesis / 223
9.8.2. Directed, Sequence-Specific Disulfide Cross-Linking in
Water / 224
9.9. Conclusions and Future Perspectives / 230
Acknowledgments / 231
References / 231
XÜ CONTENTS
10. BIOINSPIRED SUPRAMOLECULAR DESIGN IN POLYMERS
FOR ADVANCED MECHANICAL PROPERTIES 235
Zhibin Guan
10.1. Introduction / 235
10.1.1. Design of Synthetic Polymers with High Order
Structures / 235
10.1.2. Biomimetic Design of Oligomers with High
Order Structures / 236
10.2. Biomimetic Concept of Modular Polymer Design / 237
10.2.1. Titin as Model for Modular Polymer Designs / 237
10.2.2. Biomimetic Modular Domain Strategy for Polymer
Designs / 239
10.3. Results and Discussion / 240
10.3.1. Synthesis and Studies of 2-Ureido-4-pyrimidone (UPy)
Modular Polymers / 240
10.3.2. Synthesis and Single Molecule Nanomechanical Studies
of Peptidomimetic /3-Sheet Modular Polymers / 244
10.3.3. 3-D Network Polymers Containing Biomimetic Reversibly
Unfolding Crosslinkers for Advanced Mechanical
Properties / 248
10.4. Conclusion and Perspective / 251
Acknowledgments / 253
References / 253
11. STRUCTURE AND SELF-ASSEMBLY OF AMPHIPHILIC
DENDRIMERS IN WATER 259
Hui Shao and Jon R. Parquette
11.1. Introduction / 259
11.2. Structure / 260
11.2.1. Unimolecular Micelle Analogy / 260
11.2.2. Location of Terminal Groups / 263
11.2.3. Polyelectrolyte Dendrimers / 265
11.3. Self-Assembly and Aggregation / 269
11.3.1. Dendrimers and Dendrons / 269
11.3.2. Linear-Dendritic Multiblock Copolymers / 273
11.3.3. Hydrophilic-Hydrophobic Balance / 275
11.3.4. Steric Impact of Dendritic Block / 275
11.3.5. Rigid Linear Block Copolymers / 279
11.3.6. Supramolecular Gels / 282
CONTENTS XÜi
11.4. Folded Amphiphilic Dendrimers / 283
11.4.1. Conformational Switching in Water / 285
11.4.2. Amphiphilic Self-Assembly of Peptide-Dendrons / 286
11.5. Langmuir-Blodgett Monolayers / 289
11.5.1. Effect of Hydrophobic/Hydrophilic Balance / 290
11.5.2. Packing Effect / 293
11.5.3. Photoresponsive Monolayers / 294
11.5.4. Fullerene Monolayers / 295
11.6. Conclusion / 297
References / 297
PART III BIOMOLECULAR RECOGNITION USING
POLYMERS 307
12. COLORIMETRIC SENSING AND BIOSENSING USING
FUNCTIONALIZED CONJUGATED POLYMERS 309
Amit Basu
12.1. Introduction / 309
12.2. PDA / 310
12.2.1. Glycolipids / 311
12.2.2. OtherLigands / 314
12.2.3. Small Molecules / 314
12.2.4. Cation and pH Sensors / 315
12.2.5. Membrane-Binding Peptides / 316
12.2.6. Membrane Active Enzymes / 317
12.2.7. Pattern Recognition / 317
12.2.8. WholeCells / 318
12.2.9. Supported PDAs / 319
12.3. Polythiophenes / 323
12.4. Other Materials / 328
12.5. Conclusion / 328
References / 329
13. GLYCODENDRIMERS AND OTHER MACROMOLECULES
BEARING MULTIPLE CARBOHYDRATES 335
Mary J. Cloninger
13.1. Introduction / 335
13.2. Dendrimers to Glycodendrimers / 338
XIV CONTENTS
13.3. Multivalency / 342
13.4. Heteromultivalent Carbohydrate Systems / 345
13.5. Comments Regarding the Synthesis of Heteromultivalent
Carbohydrate Systems / 347
13.6. Electron Paramagnetic Resonance (EPR) Characterization of
Heterogeneously Functionalized Dendrimers / 348
13.7. Conclusions and Outlook / 353
Acknowledgment / 354
References / 354
14. SUPRAMOLECULAR POLYMERIZATION OF PEPTIDES AND
PEPTIDE DERIVATIVES: NANOFIBROUS MATERIALS 359
He Dong, Virany M. Yuwono, and Jeffrey D. Hartgerink
14.1. Introduction / 359
14.2. Self-Assembly of Nanofibers Based on a-Helices / 361
14.3. Nanofibers Self-Assembled from ß-Sheets / 369
14.3.1. Helix-Sheet Conversion and Nanofiber Formation / 369
14.3.2. Antiparallel 0-Sheet Based Nanofibers / 372
14.3.3. Nanofibers Derived from Short Peptide
Sequences / 375
14.3.4. Parallel /3-Sheet Nanofibers / 376
14.4. Collagen Mimetics / 383
14.5. Conclusions / 387
References / 387
15. MOLECULAR IMPRINTING FOR SENSOR
APPLICATIONS 395
Xiangyang Wu and Ken D. Shimizu
15.1. Introduction to Sensing Platforms / 395
15.1.1. Utility of MIPs / 397
15.2. Synthesis of MIPs / 397
15.2.1. General Types of Imprinted Polymers
(Covalent and Noncovalent) / 397
15.2.2. Types and Preparation of MIPs / 398
15.2.3. Polymerization Conditions / 402
15.3. Recognition Properties of MIPs / 405
15.3.1. Binding Site Heterogeneity / 405
15.3.2. Limitations of the Recognition Properties
ofMIPs / 407
CONTENTS XV
15.4. Polymer Formats and Morphologies / 409
15.4.1. Ground MIP Particles / 409
15.4.2. Thin Films and Membranes / 411
15.4.3. Self-Assembled Monolayers / 412
15.5. Application of MIPs in Sensing / 413
15.5.1. General Considerations / 413
15.5.2. Competitive Binding Assays / 414
15.5.3. Mass-Sensitive Sensors / 415
15.5.4. Optical MIP Sensors / 416
15.5.5. Electrometrical MIP Sensors / 418
15.6. Conclusions and Outlook / 420
References / 420
Index 431
|
| adam_txt |
CONTENTS
Preface xvii
Acknowledgments xix
List of Contributors xxi
List of Figures xxv
List of Tables xlvii
Editor Biographies xlix
PART I FUNDAMENTALS OF SUPRAMOLECULAR
POLYMERS 1
1. A BRIEF INTRODUCTION TO SUPRAMOLECULAR
CHEMISTRY IN A POLYMER CONTEXT 3
Raymond J. Thibault and Vincent M. Rotello
l. 1. Introduction and Background / 3
1.2. Main-Chain Versus Side-Chain Supramolecular Polymers / 4
References / 6
vii
VÜi CONTENTS
2. MOLECULAR RECOGNITION USING AMPHIPHILIC
MACROMOLECULES 9
Malar A. Azagarsamy, K. Krishnamoorthy, and S. Thayumanavan
2.1. Introduction / 9
2.2. Amphiphilic Block Copolymers / 11
2.2.1. Nonspecific Interactions / 13
2.2.2. Specific Interactions / 17
2.3. Amphiphilic Homopolymers / 22
2.3.1. Container Properties / 24
2.3.2. Recognition of Protein Surfaces / 25
2.3.3. Protein Sensing / 26
2.3.4. Recognition and Detection of Peptides / 28
2.4. Amphiphilic Dendrimers / 29
2.5. Conclusions / 29
Acknowledgment / 30
References / 30
3. SUPRAMOLECULAR CONTROL OF MECHANICAL
PROPERTIES IN SINGLE MOLECULES, INTERFACES,
AND MACROSCOPIC MATERIALS 37
David M. Loveless, Farrell R. Kersey, and Stephen L. Craig
3.1. Introduction and Background / 37
3.2. Mechanical Properties of Linear SPs / 40
3.3. Mechanical Properties of SP Networks / 46
3.4. Mechanical Properties in SPs at Interfaces / 50
3.5. Mechanical Forces and Supramolecular Interactions / 55
3.6. Conclusions / 57
References / 58
PART II POLYMER FORMATION AND SELF-ASSEMBLY 63
4. HYDROGEN BOND FUNCTIONALIZED BLOCK
COPOLYMERS AND TELECHELIC OLIGOMERS 65
Brian D. Mather and Timothy E. Long
4.1. Scientific Rationale and Perspective / 65
4.2. Hydrogen Bonding Interactions in Macromolecular Design / 66
4.2.1. Fundamentals of Hydrogen Bonding / 66
CONTENTS iX
4.2.2. Performance Advantages of Hydrogen Bond
Containing Polymers / 69
4.3. Hydrogen Bond Containing Block Copolymers / 73
4.3.1. Block Copolymers Involving Single Hydrogen Bonding
Groups / 74
4.3.2. Nucleobase Containing Hydrogen Bonding Block
Copolymers / 76
4.3.3. Block Copolymers Containing DNA Oligonucleotides / 80
4.3.4. Block Copolymers Containing Other Hydrogen Bonding
Arrays / 83
4.3.5. Order-Disorder Transitions (ODTs) in Hydrogen Bonding
Block Copolymers / 84
4.4. Telechelic Hydrogen Bond Functional Polymers / 85
4.5. Combining Hydrogen Bonding with Other Noncovalent Interactions / 90
4.6. Reversible Attachment of Guest Molecules via Hydrogen Bonding / 91
4.7. Conclusions and Summary / 93
References / 94
5. NONCOVALENT SIDE CHAIN MODIFICATION 103
Kamlesh P. Nair and Marcus Weck
5.1. Introduction / 103
5.1.1. Supramolecular Polymers / 104
5.2. Strategies Toward Noncovalent Side Chain Functionalization of
Polymeric Scaffolds / 105
5.2.1. Side Chain Functionalization Using Hydrogen Bonding / 105
5.2.2. Side Chain Functionalization Using Metal Coordination / 108
5.2.3. Side Chain Functionalization Using Coulombic Interactions / 109
5.3. Noncovalent Multifunctionalization of the Side Chains of Polymeric
Scaffolds / 111
5.3.1. Combination of Hydrogen Bonding and Metal
Coordination Interactions / 112
5.3.2. Combination of Hydrogen Bonding and Coulombic Charges / 114
5.3.3. Multiple Hydrogen Bonding Interactions: Self-Sorting on
Polymers / 115
5.3.4. Terpolymer Functionalization Strategies: Combing
Hydrogen Bonding, Metal Coordination, and
Pseudorotaxane Formation / 116
5.4. Applications of Noncovalently Functionalized Side Chain
Copolymers / 118
5.4.1. Seif-Assembled Functional Materials / 118
X CONTENTS
5.4.2. Network Formation Using Side Chain Supramolecular
Polymers / 120
5.5. Conclusions and Outlook / 131
Acknowledgments / 132
References / 132
6. POLYMER-MEDIATED ASSEMBLY OF NANOPARTICLES
USING ENGINEERED INTERACTIONS 137
Hung-Ting Chen, Yuval Ofir, and Vincent M. Rotello
6.1. Introduction / 137
6.2. Design of Nanoparticles and Polymers / 138
6.3. Seif-Assembly of Polymer-Particle Nanocomposites / 139
6.3.1. Control of Interparticle Spacing / 139
6.3.2. Self-Assembly of Nanoparticles Mediated by Polymers on the
Planar Substrates / 142
6.3.3. Control of 3-D Hierarchical Organization in the Solution / 148
6.4. Conclusions and Outlook / 151
References / 151
7. METALLOSUPRAMOLECULAR POLYMERS, NETWORKS,
AND GELS 157
Blayne M. McKenzie and Stuart J. Rowan
7.1. Introduction / 157
7.2. Metal-Ligand Binding Motifs / 159
7.3. Linear and Macrocyclic Main Chain MSPs / 161
7.4. Metallosupramolecular Networks and Gels / 169
7.5. Conclusion and Outlook / 175
References / 175
8. POLYMERIC CAPSULES: CATALYSIS AND
DRUG DELIVERY 179
Brian P. Mason, Jeremy L. Steinbacher, and D. Tyler McQuade
8.1. Introduction / 179
8.2. Methods of Encapsulation / 180
8.2.1. Coacervation / 182
8.2.2. Interfacial Polymerization / 182
8.2.3. Colloidosomes / 183
8.2.4. Colloidal Templating / 184
8.2.5. Vesicles / 185
CONTENTS Xi
8.3. Catalyst Encapsulation / 186
8.3.1. General / 186
8.3.2. Encapsulated Catalysts / 188
8.4. Drug Delivery with Microcapsules / 191
8.4.1. Homogeneous Particles / 191
8.4.2. Interfacial Polymerization / 192
8.4.3. Colloidal Templates / 192
8.4.4. Vesicles / 193
8.5. Conclusion / 197
References / 197
9. SEQUENCE-SPECIFIC HYDROGEN BONDED
UNITS FOR DIRECTED ASSOCIATION,
ASSEMBLY, AND LIGATION 207
Bing Gong
9.1. Introduction / 207
9.2. General Design: Information-Storing Molecular Duplexes
Based on the Recombination of H Bond Donors
and Acceptors / 208
9.3. Quadruply H Bonded Duplexes with Sequence-Independent
Stability / 209
9.4. Tuning Binding Strength by Varying the Number of InterStrand
H Bonds / 212
9.5. Probing Sequence Specificity / 213
9.6. Unexpected Discovery: Duplexes Containing
Folded Strands / 216
9.7. Directed Assembly: Formation of /3-Sheets and Supramolecular Block
Copolymers / 219
9.7.1. Directed Assembly: Templated Formation of Two-Stranded
/3-Sheets / 219
9.7.2. Supramolecular Block Copolymers / 220
9.8. Integrating Noncovalent and Covalent Interactions:
Directed Olefin Metathesis and Disulfide Bond
Formation / 223
9.8.1. Templated Olefin Cross-Metathesis / 223
9.8.2. Directed, Sequence-Specific Disulfide Cross-Linking in
Water / 224
9.9. Conclusions and Future Perspectives / 230
Acknowledgments / 231
References / 231
XÜ CONTENTS
10. BIOINSPIRED SUPRAMOLECULAR DESIGN IN POLYMERS
FOR ADVANCED MECHANICAL PROPERTIES 235
Zhibin Guan
10.1. Introduction / 235
10.1.1. Design of Synthetic Polymers with High Order
Structures / 235
10.1.2. Biomimetic Design of Oligomers with High
Order Structures / 236
10.2. Biomimetic Concept of Modular Polymer Design / 237
10.2.1. Titin as Model for Modular Polymer Designs / 237
10.2.2. Biomimetic Modular Domain Strategy for Polymer
Designs / 239
10.3. Results and Discussion / 240
10.3.1. Synthesis and Studies of 2-Ureido-4-pyrimidone (UPy)
Modular Polymers / 240
10.3.2. Synthesis and Single Molecule Nanomechanical Studies
of Peptidomimetic /3-Sheet Modular Polymers / 244
10.3.3. 3-D Network Polymers Containing Biomimetic Reversibly
Unfolding Crosslinkers for Advanced Mechanical
Properties / 248
10.4. Conclusion and Perspective / 251
Acknowledgments / 253
References / 253
11. STRUCTURE AND SELF-ASSEMBLY OF AMPHIPHILIC
DENDRIMERS IN WATER 259
Hui Shao and Jon R. Parquette
11.1. Introduction / 259
11.2. Structure / 260
11.2.1. Unimolecular Micelle Analogy / 260
11.2.2. Location of Terminal Groups / 263
11.2.3. Polyelectrolyte Dendrimers / 265
11.3. Self-Assembly and Aggregation / 269
11.3.1. Dendrimers and Dendrons / 269
11.3.2. Linear-Dendritic Multiblock Copolymers / 273
11.3.3. Hydrophilic-Hydrophobic Balance / 275
11.3.4. Steric Impact of Dendritic Block / 275
11.3.5. Rigid Linear Block Copolymers / 279
11.3.6. Supramolecular Gels / 282
CONTENTS XÜi
11.4. Folded Amphiphilic Dendrimers / 283
11.4.1. Conformational Switching in Water / 285
11.4.2. Amphiphilic Self-Assembly of Peptide-Dendrons / 286
11.5. Langmuir-Blodgett Monolayers / 289
11.5.1. Effect of Hydrophobic/Hydrophilic Balance / 290
11.5.2. Packing Effect / 293
11.5.3. Photoresponsive Monolayers / 294
11.5.4. Fullerene Monolayers / 295
11.6. Conclusion / 297
References / 297
PART III BIOMOLECULAR RECOGNITION USING
POLYMERS 307
12. COLORIMETRIC SENSING AND BIOSENSING USING
FUNCTIONALIZED CONJUGATED POLYMERS 309
Amit Basu
12.1. Introduction / 309
12.2. PDA / 310
12.2.1. Glycolipids / 311
12.2.2. OtherLigands / 314
12.2.3. Small Molecules / 314
12.2.4. Cation and pH Sensors / 315
12.2.5. Membrane-Binding Peptides / 316
12.2.6. Membrane Active Enzymes / 317
12.2.7. Pattern Recognition / 317
12.2.8. WholeCells / 318
12.2.9. Supported PDAs / 319
12.3. Polythiophenes / 323
12.4. Other Materials / 328
12.5. Conclusion / 328
References / 329
13. GLYCODENDRIMERS AND OTHER MACROMOLECULES
BEARING MULTIPLE CARBOHYDRATES 335
Mary J. Cloninger
13.1. Introduction / 335
13.2. Dendrimers to Glycodendrimers / 338
XIV CONTENTS
13.3. Multivalency / 342
13.4. Heteromultivalent Carbohydrate Systems / 345
13.5. Comments Regarding the Synthesis of Heteromultivalent
Carbohydrate Systems / 347
13.6. Electron Paramagnetic Resonance (EPR) Characterization of
Heterogeneously Functionalized Dendrimers / 348
13.7. Conclusions and Outlook / 353
Acknowledgment / 354
References / 354
14. SUPRAMOLECULAR POLYMERIZATION OF PEPTIDES AND
PEPTIDE DERIVATIVES: NANOFIBROUS MATERIALS 359
He Dong, Virany M. Yuwono, and Jeffrey D. Hartgerink
14.1. Introduction / 359
14.2. Self-Assembly of Nanofibers Based on a-Helices / 361
14.3. Nanofibers Self-Assembled from ß-Sheets / 369
14.3.1. Helix-Sheet Conversion and Nanofiber Formation / 369
14.3.2. Antiparallel 0-Sheet Based Nanofibers / 372
14.3.3. Nanofibers Derived from Short Peptide
Sequences / 375
14.3.4. Parallel /3-Sheet Nanofibers / 376
14.4. Collagen Mimetics / 383
14.5. Conclusions / 387
References / 387
15. MOLECULAR IMPRINTING FOR SENSOR
APPLICATIONS 395
Xiangyang Wu and Ken D. Shimizu
15.1. Introduction to Sensing Platforms / 395
15.1.1. Utility of MIPs / 397
15.2. Synthesis of MIPs / 397
15.2.1. General Types of Imprinted Polymers
(Covalent and Noncovalent) / 397
15.2.2. Types and Preparation of MIPs / 398
15.2.3. Polymerization Conditions / 402
15.3. Recognition Properties of MIPs / 405
15.3.1. Binding Site Heterogeneity / 405
15.3.2. Limitations of the Recognition Properties
ofMIPs / 407
CONTENTS XV
15.4. Polymer Formats and Morphologies / 409
15.4.1. Ground MIP Particles / 409
15.4.2. Thin Films and Membranes / 411
15.4.3. Self-Assembled Monolayers / 412
15.5. Application of MIPs in Sensing / 413
15.5.1. General Considerations / 413
15.5.2. Competitive Binding Assays / 414
15.5.3. Mass-Sensitive Sensors / 415
15.5.4. Optical MIP Sensors / 416
15.5.5. Electrometrical MIP Sensors / 418
15.6. Conclusions and Outlook / 420
References / 420
Index 431 |
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| index_date | 2024-07-02T22:02:47Z |
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| spelling | Molecular recognition and polymers control of polymer structure and self-assembly ed. by Vincent M. Rotello ; S. Thayumanavan Hoboken, NJ Wiley 2008 XLV, 436 S. txt rdacontent n rdamedia nc rdacarrier Ill., graph. Darst. Biomimetic polymers Molecular recognition Supramolecular chemistry Supramolekulare Chemie (DE-588)4306141-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Supramolekulare Chemie (DE-588)4306141-2 s DE-604 Rotello, Vincent M. Sonstige oth Thayumanavan, Sankaran Sonstige oth http://www.loc.gov/catdir/enhancements/fy0811/2008007590-d.html Publisher description http://www.loc.gov/catdir/enhancements/fy0811/2008007590-t.html Table of contents only HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016735692&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Molecular recognition and polymers control of polymer structure and self-assembly Biomimetic polymers Molecular recognition Supramolecular chemistry Supramolekulare Chemie (DE-588)4306141-2 gnd |
| subject_GND | (DE-588)4306141-2 (DE-588)4143413-4 |
| title | Molecular recognition and polymers control of polymer structure and self-assembly |
| title_auth | Molecular recognition and polymers control of polymer structure and self-assembly |
| title_exact_search | Molecular recognition and polymers control of polymer structure and self-assembly |
| title_exact_search_txtP | Molecular recognition and polymers control of polymer structure and self-assembly |
| title_full | Molecular recognition and polymers control of polymer structure and self-assembly ed. by Vincent M. Rotello ; S. Thayumanavan |
| title_fullStr | Molecular recognition and polymers control of polymer structure and self-assembly ed. by Vincent M. Rotello ; S. Thayumanavan |
| title_full_unstemmed | Molecular recognition and polymers control of polymer structure and self-assembly ed. by Vincent M. Rotello ; S. Thayumanavan |
| title_short | Molecular recognition and polymers |
| title_sort | molecular recognition and polymers control of polymer structure and self assembly |
| title_sub | control of polymer structure and self-assembly |
| topic | Biomimetic polymers Molecular recognition Supramolecular chemistry Supramolekulare Chemie (DE-588)4306141-2 gnd |
| topic_facet | Biomimetic polymers Molecular recognition Supramolecular chemistry Supramolekulare Chemie Aufsatzsammlung |
| url | http://www.loc.gov/catdir/enhancements/fy0811/2008007590-d.html http://www.loc.gov/catdir/enhancements/fy0811/2008007590-t.html http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016735692&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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