Development of novel antimicrobial agents: emerging strategies
Saved in:
| Format: | Book |
|---|---|
| Language: | Undetermined |
| Published: |
Norfolk
Horizon Scient. Press
2001
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XI, 284 S. |
| ISBN: | 1898486239 |
Staff View
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Record in the Search Index
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| adam_text | Contents
List of Contributors vii
Preface x
Section 1 - The Problem of Antimicrobial Resistance
1. Are We on the Threshold of the Post-Antibiotic Era? 1
Karl Lohner and Erich Staudegger
2. Origins and Evolution of Antibiotic and Multiple Antibiotic 17
Resistance in Bacteria
Ruth M. Hall and Christina M. Collis
3. Antimicrobial Peptide Resistance Mechanisms in Bacteria 31
ArdenAspedon and Eduardo A. Groisman
Section 2 - Microbial Genomics: Novel Targets and Vaccines
4. Genetic Engineering of Novel Macrolide Antibiotics 45
Robert McDaniel and Leonard Katz
5. Granulysin, A Novel Mediator of Antimicrobial Activity of Cytolytic T-cells 61
Steffen Stenger, Alan M. Krensky and Robert L. Modlin
6. The Immunostimulatory Properties of Bacterial DNA 71
David S. Pisetsky
7. Bacteria-Mediated DNA Transfer for Gene Therapy and Genetic Vaccination 81
Siegfried Weiss and Trinad Chakraborty
8. Potential Mucosal Adjuvants For Human Use 91
Mari Ohmura, Raymond J. Jackson, Yoshifumi Takeda
and Jerry R. McGhee
9. Attenuated Bacteria as Delivery Vehicles for Helicobacter pylori Vaccines 107
Thomas G. Blanchard and Steven J. Czinn
10. Development of an Adhesin Vaccine to Prevent Urinary Tract Infection 123
Matthew A. Mulvey, Scott J. Hultgren and Solomon Langermann
Section 3 - Innate Immunity: Antimicrobial Peptides
11. Antimicrobial Peptides in Innate Immunity 139
Tomas Ganz and Robert I. Lehrer
12. The Role of Membrane Lipid Composition in Cell Targeting 149
of Antimicrobial Peptides
Karl Lohner
iv
13. Molecular Mechanisms of Membrane Perturbation by Antimicrobial Peptides 167
Katsumi Matsuzaki
14. Molecular Mechanism of Cell Selectivity by Linear Amphipatic 183
a-helical and Diasteriomeric Antimicrobial Peptides
Ziv Oren and Yechiel Shai
15. Molecular Interactions Involved in Bactericidal Activities of Lantibiotics 205
Ulrike Pag and Hans-Georg Sahl
16. Cyclic Cystine-knot (3-Stranded Antimicrobial Peptides: 215
Occurrence, Design and Synthesis
James P. Tarn, Yi-An Lu, Jin-Long Yang and Qitao Yu
17. Synthetic Combinatorial Libraries: An Emerging Approach 241
Toward the Identification of Novel Antibiotics
Sylvie E. Blondelle
18. The Commercial Development of the Antimicrobial Peptide Pexiganan 261
Michael Zasloff
Appendix 271
Index 273
v
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| illustrated | Not Illustrated |
| indexdate | 2024-07-09T23:12:55Z |
| institution | BVB |
| isbn | 1898486239 |
| language | Undetermined |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-022026515 |
| oclc_num | 917977154 |
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| owner_facet | DE-188 |
| physical | XI, 284 S. |
| publishDate | 2001 |
| publishDateSearch | 2001 |
| publishDateSort | 2001 |
| publisher | Horizon Scient. Press |
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| spelling | Development of novel antimicrobial agents emerging strategies ed. by Karl Lohner Norfolk Horizon Scient. Press 2001 XI, 284 S. txt rdacontent n rdamedia nc rdacarrier Antiinfective Agents cabt Lohner, Karl Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022026515&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Development of novel antimicrobial agents emerging strategies Antiinfective Agents cabt |
| title | Development of novel antimicrobial agents emerging strategies |
| title_auth | Development of novel antimicrobial agents emerging strategies |
| title_exact_search | Development of novel antimicrobial agents emerging strategies |
| title_full | Development of novel antimicrobial agents emerging strategies ed. by Karl Lohner |
| title_fullStr | Development of novel antimicrobial agents emerging strategies ed. by Karl Lohner |
| title_full_unstemmed | Development of novel antimicrobial agents emerging strategies ed. by Karl Lohner |
| title_short | Development of novel antimicrobial agents |
| title_sort | development of novel antimicrobial agents emerging strategies |
| title_sub | emerging strategies |
| topic | Antiinfective Agents cabt |
| topic_facet | Antiinfective Agents |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=022026515&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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