Cell biology:
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Philadelphia [u.a.]
Saunders
1975
|
| Edition: | 6. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XV, 615 S. |
| ISBN: | 072163043X |
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MARC
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Record in the Search Index
| _version_ | 1805077929324969984 |
|---|---|
| adam_text |
IMAGE 1
CONTENTS
PART ONE
INTRODUCTION TO CELL BIOLOGY
CHAPTER ONE INTRODUCTION. HISTORY AND GENERAL CONCEPTS OF CELL BIOLOGY 3
LEVELS OF ORGANIZATION IN BIOLOGY 3
LIMITS AND DIMENSIONS IN BIOLOGY 4
SUMMARY: LEVELS OF ORGANIZATION 7
HISTORY OF CELL BIOLOGY 7
CELL THEORY 7
CYTOLOGY AND GENETICS: CYTOGENETICS 8
CYTOLOGY AND PHYSIOLOGY: CELL PHYSIOLOGY 9
CYTOLOGY AND BIOCHEMISTRY: CYTOCHEMISTRY 9
ULTRASTRUCTURE AND MOLECULAR BIOLOGY 10
LITERARY SOURCES IN CELL BIOLOGY 11
REFERENCES 11
ADDITIONAL READING 11
CHAPTER TWO GENERAL STRUCTURE OF THE CELL 13
PROKARYOTIC CELLS 13
THE BACTERIAL CELL 13
THE SMALLEST MASS OF LIVING MATTER 14
EUKARYOTIC CELLS 15
SHAPE 15
SIZE 16
STRUCTURE OF THE LIVING CELL 16
STRUCTURE OF FIXED CELLS 18
SUMMARY: GENERAL CELL STRUCTURE 21
THE NUCLEUS AND CHROMOSOMES 22
THE CELL CYCLE 22
MORPHOLOGY OF THE NUCLEUS 23
GENERAL STRUCTURE OF THE INTERPHASE NUCLEUS 23
MITOSIS AND MEIOSIS 25
VII
IMAGE 2
VIII CONTENTS
MITOSIS 25
MEIOSIS 25
CHROMOSOMES 28
MORPHOLOGY 28
SUMMARY: THE NUCLEUS AND CELL DIVISION 31
SUMMARY: PROKARYOTIC AND EUKARYOTIC CELLS 32
REFERENCES 33
ADDITIONAL READING 33
PART TWO
MOLECULAR COMPONENTS AND METABOLISM OF THE CELL
CHAPTER THREE CHEMICAL COMPONENTS OF THE CELL 37
MOLECULAR POPULATION OF THE CELL 37
WATER, FREE AND BOUND 37
SALTS AND IONS 38
MACROMOLECULES 38
AMINO ACIDS AND PROTEINS 38
ELECTRICAL CHARGES OF PROTEINS 43
CARBOHYDRATES 44
COMPLEX POLYSACCHARIDES AND GLYCOPROTEINS 44
LIPIDS 46
SUMMARY: CELLULAR CHEMISTRY 48
NUCLEIC ACIDS 49
CHEMICAL COMPOSITION 49
THE STRUCTURE OF DNA 51
THE WATSON-CRICK MODEL 51
DENATURATION AND RENATURATION OF DNA; HYBRIDIZATION 53 STRUCTURE OF RN A
55
SUMMARY: NUCLEIC ACIDS 55
ADDITIONAL READING 56
CHAPTER FOUR
ENZYMES, BIOENERGETICS, AND CELL RESPIRATION 58
ENZYMES 58
SPECIFICITY 59
ENZYME ACTIVATION; CO-FACTORS 59
ACTIVE SITE OF THE ENZYME 60
ENZYME KINETICS 61
ENZYME INHIBITION 62
I SOENZYMES 63
ALLOSTERIC ENZYMES 63
REGULATION OF ENZYME ACTIVITY 64
ENZYME INTERCONVERSIONS 65
CYCLIC AMP AND HORMONAL CONTROL 66
IMAGE 3
CONTENTS IX
SUMMARY: ENZYMES IN THE CELL 67
BIOENERGETICS 69
CONCEPT OF ENTROPY 69
CELL METABOLISM 70
ENERGY CYCLE 70
ENERGY TRANSFORMATION 71
CELL RESPIRATION 73
ANAEROBIC GLYCOLYSIS 73
AEROBIC RESPIRATION 73
THE KREBS CYCLE 75
RESPIRATORY CHAIN 75
OXIDATIVE PHOSPHORYLATION 75
SUMMARY: BIOENERGETICS AND CELL RESPIRATION 76
REFERENCES 77
ADDITIONAL READING 77
PART THREE
METHODS FOR THE STUDY OF THE CELL
CHAPTER FIVE INSTRUMENTAL ANALYSIS OF BIOLOGICAL STRUCTURES 81
RESOLVING POWER OF THE M ICROSCOPE 81
METHODS FOR INCREASING CONTRAST 82
PHASE MICROSCOPY 82
INTERFERENCE MICROSCOPY 85
DARKFIELD MICROSCOPY 86
POLARIZATION MICROSCOPY 86
ELECTRON MICROSCOPY 88
X-RAY DIFFRACTION 94
SUMMARY: MICROSCOPY 97
REFERENCES 99
ADDITIONAL READING 99
CHAPTER SIX METHODS FOR CYTOLOGIC AND CYTOCHEMICAL ANALYSIS 101
EXAMINATION OF LIVING CELLS 101
FIXATION 103
EMBEDDING AND SECTIONING 105
CYTOLOGIC STAINING 105
SUMMARY: OBSERVATION OF LIVING AND FIXED CELLS 108
HISTOCHEMISTRY AND CYTOCHEMISTRY 109
CELL FRACTIONATION METHODS 109
ZONAL CENTRIFUGATION 112
MICROCHEMISTRY AND ULTRAMICROCHEMISTRY 112
CYTOCHEMICAL AND HISTOCHEMICAL STAINING METHODS 113 HISTOCHEMICAL
METHODS BASED ON PHYSICAL DETERMINATIONS 119
IMAGE 4
CONTENTS
SUMMARY: CYTOCHEMISTRY 125
REFERENCES 127
ADDITIONAL READING 129
PART FOUR
UNITS OF STRUCTURE AND THE PLASMA MEMBRANE
CHAPTER SEVEN ELEMENTARY UNITS OF STRUCTURE IN BIOLOGICAL SYSTEMS 133
ELEMENTARY STRUCTURES AND THEIR FUNCTION 133
PRINCIPLES IN THE ASSEMBLY OF MACROMOLECULES 134 SUMMARY: ASSEMBLY OF
MACROMOLECULES 137
ELEMENTARY MEMBRANOUS STRUCTURES 139
SUMMARY: ARTIFICIAL MEMBRANE SYSTEMS 143
REFERENCES 143
ADDITIONAL READING 144
CHAPTER EIGHT THE PLASMA MEMBRANE 145
ISOLATION OF THE PLASMA MEMBRANES 145
CHEMICAL COMPOSITION 145
SUMMARY: CHEMISTRY OF THE PLASMA MEMBRANE 149
STRUCTURE OF THE PLASMA MEMBRANE 149
SUMMARY: STRUCTURE OF THE PLASMA MEMBRANE 151
THE FLUID MOSAIC MODEL OF MEMBRANE STRUCTURE 156
SUMMARY: THE "FLUID MOSAIC" MODEL 158
DIFFERENTIATIONS AT THE CELL SURFACE 158
COATS OF THE CELL MEMBRANE 164
GLY COCALYX 164
SUMMARY: THE CELL SURFACE 166
REFERENCES 166
ADDITIONAL READING 168
PART FIVE
THE CYTOPLASM AND CYTOPLASMIC ORGANELLES
CHAPTER NINE THE CYTOPLASM AND VACUOLAR SYSTEM 171
CYTOPLASMIC MATRIX 171
PROPERTIES OF THE CYTOPLASMIC MATRIX 173
SUMMARY: CYTOPLASMIC MATRIX 175
CYTOPLASMIC VACUOLAR SYSTEM 175
GENERAL MORPHOLOGY OF THE VACUOLAR SYSTEM 176
IMAGE 5
CONTENTS XI
SUMMARY: CYTOPLASMIC VACUOLAR SYSTEM 181
FRACTIONATION OF THE VACUOLAR SYSTEM 181
SUMMARY: MICROSOMAL FRACTION 185
SUMMARY: ENDOPLASMIC RETICULUM 188
GOLGI COMPLEX 188
ISOLATION OF THE GOLGI COMPLEX 193
SUMMARY: ISOLATION OF THE GOLGI COMPLEX 197
REFERENCES ,. 198
ADDITIONAL READING 199
CHAPTER TEN MITOCHONDRIA 200
MORPHOLOGY 200
DISTRIBUTION 201
SUMMARY: NATURE OF MITOCHONDRIA 203
STRUCTURE 203
SUMMARY: STRUCTURE OF MITOCHONDRIA 210
ISOLATION OF MITOCHONDRIA AND MITOCHONDRIAL MEMBRANES. 210 SUMMARY:
ISOLATION OF MITOCHONDRIA 214
MOLECULAR STRUCTURE AND FUNCTION 214
SUMMARY: ENERGY TRANSDUCTION IN MITOCHONDRIA 218 PERMEABILITY OF
MITOCHONDRIA 219
SUMMARY: OTHER FUNCTIONS OF MITOCHONDRIA 223
MITOCHONDRIA AS SEMIAUTONOMOUS ORGANELLES 224
REFERENCES 228
ADDITIONAL READING 229
CHAPTER ELEVEN THE PLANT CELL AND THE CHLOROPLAST 231
CHARACTERISTICS OF PLANT CELLS 231
SUMMARY: CHARACTERISTICS OF PLANT CELLS 237
PLASTIDS 237
CHLOROPLASTS 238
SUMMARY: PLASTIDS 243
PHOTOSYNTHESIS 244
SUMMARY: PHOTOSYNTHESIS AND THE CHLOROPLAST 250
REFERENCES 252
ADDITIONAL READING 254
PART SIX
CELLULAR BASIS OF CYTOGENETICS
CHAPTER TWELVE
THE INTERPHASE NUCLEUS AND THE CHROMOSOMES 257
THE NUCLEAR ENVELOPE AND NUCLEAR PERMEABILITY 257
SUMMARY: THE NUCLEAR ENVELOPE 261
IMAGE 6
XII CONTENTS
ULTRASTRUCTURE OF THE INTERPHASE NUCLEUS 261
THE NUCLEOLUS 263
RIBONUCLEOPROTEIN STRUCTURES 266
HETEROCHROMATIN AND SATELLITE DNA 268
SUMMARY: ORGANIZATION OF THE INTERPHASE NUCLEUS 271 REFERENCES 272
ADDITIONAL READING 273
CHAPTER THIRTEEN MITOSIS 274
MITOSIS 274
SUMMARY: EVENTS IN MITOSIS 277
CONDENSATION CYCLE OF CHROMOSOMES 277
SUMMARY: STRUCTURE OF THE CHROMOSOME 280
FINE STRUCTURE AND FUNCTIONAL ROLE OF THE MITOTIC APPARATUS 281
CYTOKINESIS IN PLANT CELLS 287
SUMMARY: THE MITOTIC APPARATUS 289
REFERENCES 290
ADDITIONAL READING 291
CHAPTER FOURTEEN MEIOSIS 292
ANALYSIS OF MEIOSIS 293
MEIOTIC DIVISION I 294
MEIOTIC DIVISION II 300
SUMMARY: EVENTS IN MEIOSIS 300
SYNAPTONEMAL COMPLEX AND RECOMBINATION 302
SUMMARY: THE SYNAPTONEMAL COMPLEX 305
GIANT CHROMOSOMES 305
SUMMARY: GIANT CHROMOSOMES 310
REFERENCES 310
ADDITIONAL READING 311
CHAPTER FIFTEEN CYTOGENETICS. CHROMOSOMAL BASES OF GENETICS 312
LAWS OF HEREDITY 312
LINKAGE AND RECOMBINATION 315
SUMMARY: FUNDAMENTAL GENETICS 318
CHROMOSOMAL CHANGES 319
CHANGES IN CHROMOSOME NUMBER 323
SUMMARY: VARIATIONS IN CHROMOSOMES 326
CYTOGENETIC EFFECT OF RADIATION 327
CYTOGENETIC ACTION OF CHEMICAL AGENTS 330
CYTOGENETICS AND EVOLUTION 332
SUMMARY: MUTAGENS, MUTATIONS, AND EVOLUTION 333
REFERENCES 334
ADDITIONAL READING 334
IMAGE 7
CONTENTS XIII
CHAPTER SIXTEEN
SEX DETERMINATION AND HUMAN CYTOGENETICS 336
SEX DETERMINATION 336
SEX-LINKED INHERITANCE 342
SUMMARY: CYTOGENETICS OF SEX DETERMINATION 343
HUMAN CYTOGENETICS 344
THE NORMAL HUMAN KARYOTYPE 345
ABNORMAL HUMAN KARYOTYPES 347
SUMMARY: ABERRATIONS OF HUMAN CHROMOSOMES 35 1
REFERENCES 352
ADDITIONAL READING 352
PART SEVEN
MOLECULAR BIOLOGY
CHAPTER SEVENTEEN CYTOCHEMISTRY OF THE NUCLEUS, THE CELL CYCLE, AND DNA
DUPLICATION 359
CYTOCHEMISTRY OF THE NUCLEUS 360
DNA CONTENT OF THE NUCLEUS 360
SUMMARY: CHEMISTRY OF THE NUCLEUS 364
DNA AND THE CELL CYCLE 365
RNA SYNTHESIS AND THE CELL CYCLE 377
PROTEIN SYNTHESIS AND THE CELL CYCLE 378
SUMMARY: THE CELL CYCLE 379
REFERENCES 382
ADDITIONAL READING 383
CHAPTER EIGHTEEN
RIBOSOMES: STRUCTURE AND BIOGENESIS 384
CHEMICAL COMPOSITION 387
SUMMARY: STRUCTURE AND COMPOSITION OF RIBOSOMES 389 BIOGENESIS OF
RIBOSOMES 391
SUMMARY: BIOGENESIS OF RIBOSOMES 401
REFERENCES 402
ADDITIONAL READING 403
CHAPTER NINETEEN PROTEIN SYNTHESIS AND MOLECULAR GENETICS 404
THE GENETIC CODE 409
SUMMARY: MOLECULAR GENETICS 411
TRANSCRIPTION OF GENETIC INFORMATION 412
MESSENGER RNA 412
TRANSFER RNA 417
IMAGE 8
XIV CONTENTS
SUMMARY: TRANSCRIPTION 421
RIBOSOMES AND PROTEIN SYNTHESIS 422
SUMMARY: PROTEIN SYNTHESIS 431
GENETIC REGULATION 432
SUMMARY: GENETIC REGULATION 437
REFERENCES 438
ADDITIONAL READING 439
CHAPTER TWENTY CELL DIFFERENTIATION AND CELLULAR INTERACTION 441
NUCLEOCYTOPLASMIC INTERRELATIONS IN PROTOZOA 442
MOLECULAR EVENTS IN AMPHIBIAN EGGS 443
MECHANISMS OF GENE EXPRESSION 445
SUMMARY: CELL DIFFERENTIATION 447
GENE REGULATION IN EUKARYONS 448
SUMMARY: REGULATION OF GENETIC INFORMATION 455
RENEWAL OF CELL POPULATIONS 457
CELLULAR INTERACTION 458
SUMMARY: INTERCELLULAR INTERACTIONS 462
REFERENCES 463
ADDITIONAL READING 464
PART EIGHT
CELL PHYSIOLOGY
CHAPTER TWENTY-ONE CELL PERMEABILITY, ENDOCYTOSIS, LYSOSOMES, AND
PEROXISOMES 471
DIFFUSION OR PASSIVE PERMEABILITY 472
CELL PERMEABILITY AND ACTIVE TRANSPORT 474
SUMMARY: CELL PERMEABILITY AND ACTIVE TRANSPORT 479 ENDOCY TOSIS 481
PINOCYTOSIS 482
THE LYSOSOME 485
PEROXISOMES AND GLYOXYSOMES (MICROBODIES) 492 SUMMARY: ENDOCYTOSIS,
LYSOSOMES, AND PEROXISOMES 493 REFERENCES 494
ADDITIONAL READING 495
CHAPTER TWENTY-TWO PRIMITIVE CELL MOVEMENTS. CILIA, CENTRIOLES,
MICROTUBULES, AND MICROFILAMENTS 497
CILIA AND CILIARY MOTION 497
BASAL BODIES (KINETOSOMES) AND CENTRIOLES 501
ORIGIN OF CILIA, BASAL BODIES, AND CENTRIOLES 507
IMAGE 9
CONTENTS XV
SUMMARY: STRUCTURE, MOTION, AND ORIGIN OF CILIA AND FLAGELLA 508
MICROTUBULES 510
SUMMARY: PROPERTIES OF MICROTUBULES 512
CYTOPLASMIC STREAMING 513
AMEBOID MOTION 513
MICROFILAMENTS AND CELL MOTION 516
SUMMARY: CYCLOSIS, AMEBOID MOTION, AND MICROFILAMENTS 519 REFERENCES 520
ADDITIONAL READING 521
CHAPTER TWENTY-THREE MOLECULAR BIOLOGY OF MUSCLE 523
BIOCHEMISTRY OF MUSCLE 529
THE SLIDING THEORY OF MUSCLE CONTRACTION 531
SARCOPLASMIC RETICULUM 534
SUMMARY: MOLECULAR BIOLOGY OF MUSCLE 537
REFERENCES 539
ADDITIONAL READING 540
CHAPTER TWENTY-FOUR CELLULAR AND MOLECULAR NEUROBIOLOGY 541
GENERAL ORGANIZATION OF A NEURON 542
SUMMARY: GENERAL ORGANIZATION OF THE NEURON 551
SYNAPTIC TRANSMISSION 553
MOLECULAR BIOLOGY OF RECEPTORS 564
SUMMARY: SYNAPTIC TRANSMISSION 569
REFERENCES 571
ADDITIONAL READING 573
CHAPTER TWENTY-FIVE CELL SECRETION 575
SUMMARY: SECRETION; METHODS OF STUDY 576
MORPHOLOGY OF THE SECRETORY CYCLE 577
SUMMARY: MORPHOLOGY OF THE SECRETORY CYCLE 583
CYTOCHEMISTRY OF THE SECRETORY CYCLE 584
SUMMARY: CYTOCHEMISTRY OF THE SECRETORY CYCLE 589
REFERENCES 592
ADDITIONAL READING 592
INDEX 595 |
| any_adam_object | 1 |
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| author_GND | (DE-588)158255364 (DE-588)1065685378 |
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| id | DE-604.BV026263841 |
| illustrated | Not Illustrated |
| indexdate | 2024-07-20T06:21:00Z |
| institution | BVB |
| isbn | 072163043X |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-021846565 |
| oclc_num | 884618125 |
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| owner | DE-188 |
| owner_facet | DE-188 |
| physical | XV, 615 S. |
| publishDate | 1975 |
| publishDateSearch | 1975 |
| publishDateSort | 1975 |
| publisher | Saunders |
| record_format | marc |
| spelling | De Robertis, Eduardo D. P. 1913-1988 Verfasser (DE-588)158255364 aut Citologia general Cell biology Eduardo D. P. de Robertis ; Francisco A. Saez ; E. M. F. DeRobertis 6. ed. Philadelphia [u.a.] Saunders 1975 XV, 615 S. txt rdacontent n rdamedia nc rdacarrier Cytologie (DE-588)4070177-3 gnd rswk-swf Zelle (DE-588)4067537-3 gnd rswk-swf Cytologie (DE-588)4070177-3 s 1\p DE-604 Zelle (DE-588)4067537-3 s 2\p DE-604 Saez, Francisco A. 1898-1976 Verfasser (DE-588)1065685378 aut De Robertis, E. M. F. Verfasser aut SWB Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=021846565&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk 2\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | De Robertis, Eduardo D. P. 1913-1988 Saez, Francisco A. 1898-1976 De Robertis, E. M. F. Cell biology Cytologie (DE-588)4070177-3 gnd Zelle (DE-588)4067537-3 gnd |
| subject_GND | (DE-588)4070177-3 (DE-588)4067537-3 |
| title | Cell biology |
| title_alt | Citologia general |
| title_auth | Cell biology |
| title_exact_search | Cell biology |
| title_full | Cell biology Eduardo D. P. de Robertis ; Francisco A. Saez ; E. M. F. DeRobertis |
| title_fullStr | Cell biology Eduardo D. P. de Robertis ; Francisco A. Saez ; E. M. F. DeRobertis |
| title_full_unstemmed | Cell biology Eduardo D. P. de Robertis ; Francisco A. Saez ; E. M. F. DeRobertis |
| title_short | Cell biology |
| title_sort | cell biology |
| topic | Cytologie (DE-588)4070177-3 gnd Zelle (DE-588)4067537-3 gnd |
| topic_facet | Cytologie Zelle |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=021846565&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT derobertiseduardodp citologiageneral AT saezfranciscoa citologiageneral AT derobertisemf citologiageneral AT derobertiseduardodp cellbiology AT saezfranciscoa cellbiology AT derobertisemf cellbiology |