DNA interactions with polymers and surfactants:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Hoboken, N.J.
John Wiley
c2008
|
| Subjects: | |
| Online Access: | Publisher description Table of contents only Contributor biographical information Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | xviii, 407 p. ill. 25 cm |
| ISBN: | 9780470258187 |
Staff View
MARC
| LEADER | 00000nam a2200000zc 4500 | ||
|---|---|---|---|
| 001 | BV023400686 | ||
| 003 | DE-604 | ||
| 005 | 20080808 | ||
| 007 | t | ||
| 008 | 080717s2008 xxua||| |||| 00||| eng d | ||
| 010 | |a 2007046844 | ||
| 020 | |a 9780470258187 |c cloth |9 978-0-470-25818-7 | ||
| 035 | |a (OCoLC)181862648 | ||
| 035 | |a (DE-599)GBV550562540 | ||
| 040 | |a DE-604 |b ger |e aacr | ||
| 041 | 0 | |a eng | |
| 044 | |a xxu |c US | ||
| 049 | |a DE-703 |a DE-11 | ||
| 050 | 0 | |a QP624 | |
| 082 | 0 | |a 572.8/6 | |
| 084 | |a WD 5360 |0 (DE-625)148202: |2 rvk | ||
| 245 | 1 | 0 | |a DNA interactions with polymers and surfactants |c edited by Rita Dias and Björn Lindman |
| 264 | 1 | |a Hoboken, N.J. |b John Wiley |c c2008 | |
| 300 | |a xviii, 407 p. |b ill. |c 25 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a DNA | |
| 650 | 4 | |a Polymers | |
| 650 | 4 | |a Surface active agents | |
| 650 | 4 | |a DNA |x chemistry | |
| 650 | 4 | |a Polymers |x chemistry | |
| 650 | 4 | |a Solutions |x chemistry | |
| 650 | 4 | |a Surface-Active Agents |x chemistry | |
| 650 | 0 | 7 | |a Oberflächenchemie |0 (DE-588)4126166-5 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Polymere |0 (DE-588)4046699-1 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a DNS |0 (DE-588)4070512-2 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a DNS |0 (DE-588)4070512-2 |D s |
| 689 | 0 | 1 | |a Polymere |0 (DE-588)4046699-1 |D s |
| 689 | 0 | |5 DE-604 | |
| 689 | 1 | 0 | |a DNS |0 (DE-588)4070512-2 |D s |
| 689 | 1 | 1 | |a Oberflächenchemie |0 (DE-588)4126166-5 |D s |
| 689 | 1 | |5 DE-604 | |
| 700 | 1 | |a Dias, Rita |e Sonstige |0 (DE-588)135798906 |4 oth | |
| 856 | 4 | |u http://www.loc.gov/catdir/enhancements/fy0805/2007046844-d.html |3 Publisher description | |
| 856 | 4 | |u http://www.loc.gov/catdir/enhancements/fy0805/2007046844-t.html |3 Table of contents only | |
| 856 | 4 | |u http://www.loc.gov/catdir/enhancements/fy0827/2007046844-b.html |3 Contributor biographical information | |
| 856 | 4 | 2 | |m Digitalisierung UB Bayreuth |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016583480&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |3 Inhaltsverzeichnis |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-016583480 | ||
Record in the Search Index
| _version_ | 1804137783355244544 |
|---|---|
| adam_text | CONTENTS
Preface
xiii
Contributors
xv
1
Poiyelectrolytes. Phvsicochemical Aspects and Biological Significance
1
Magnus Ullner
1.1
Introduction
1
1.2
Poiyelectrolytes and Biological Function
1
1.3
Electrostatic Interactions
3
1.3.1
Ion Distributions and the Poisson-Boltzmann Equation
3
1.3.2
Debye-Hiickel Theory
9
1.4
Solution Properties
13
1.5
Flexibility
17
1.5.1
The Concept of Persistence Length
17
1.5.2
Interactions and the Separation of Length Scales
23
1.5.3
Polyelectrolyte Behavior: Electrostatic
Persistence Length
26
1.5.4 DNA
Persistence Length
29
References
31
2
Solution Behavior of Nucleic Acids
41
Rita S.
Dias
2.1
Biological Function of Nucleic Acids
41
2.2
Discovery of
DNA 41
2.3
Structure of Nucleic Acids
43
2.3.1 DNA 43
2.3.2
RNA
47
2.3.3
Analogues of Nucleic Acids
48
2.4
Nuclei Acids Nanostructures
48
2.4.1 DNA 48
2.4.2
RNA 50
2.5
Behavior of
DNA
in Solution 5
1
2.5.1
Ionization Equilibrium 51
2.5.2
Flexibility of Nucleic Acids
51
Vi
CONTENTS
2.6
Melting of Double-Stranded
DNA 52
2.6.1
Effect of Base Composition
53
2.6.2
Effect of Ionic Strength
53
2.6.3
Effect of
pH 53
2.6.4
Dependence on
DNA
Chain Length
54
2.6.5
Dependence on
DNA
Concentration
54
Acknowledgments
55
References
55
3
Single
DNA
Molecules: Compaction and Decompaction
59
Anatoly A. Zinchenko,
Olga
A. Pyshkina,
Andrey V. Lezov,
Vladimir G.
Sergeyev, and Kenichi Yoshikawa
3.1
Introduction
59
3.2
Condensation and Compaction of
DNA
by Surfactants
60
3.2.1
Linear
DNA
Condensation/Compaction
by Positively Charged Surfactants
60
3.2.2
Compaction of Plasmid
DNA
with Surfactants
63
3.2.3
Non-ionic Surfactants
64
3.2.4
Zwitterionic Surfactants
64
3.2.5
Decompaction of DNA-Surfactant Complex
65
3.3 DNA
Condensation by Cationic
Liposomes
65
3.4 DNA
Compaction and Decompaction by Multivalent Cations
74
3.5 DNA
Compaction by Polycations
77
3.6
Compaction of
DNA in
a Crowded Environment
of Neutral Polymer
81
3.7
Conclusion
82
References
82
4
Interaction of
DNA
with Surfactants in Solution
89
Rita S.
Dias,
Kenneth Dawson, and Maria G. Miguel
4.1
Introduction
89
4.1.1
Surfactants
89
4.1.2
Polymer-Surfactant Interactions
93
4.1.3
Polyelectrolyte-Oppositely Charged
Surfactant Interactions
94
4.1.4
DNA-Surfactant Interactions
95
4.2
DNA-Cationic Surfactant Interactions
96
4.2.1
Solution Behavior
96
4.2.2
Effect of the Surfactant Chain Length
99
4.2.3
Effect of the Surfactant Head-group
101
4.2.4
Structure of DNA-Surfactant Complexes
102
4.2.5 DNA
Is an Amphiphilic Polyelectrolyte
105
4.3 DNA
Covalent Gels and Their Interaction with Surfactants
106
CONTENTS
VII
4.4
Applications
108
4.4.1
Control of
DNA
Compaction/Decompaction
108
4.4.2
Purification
110
4.4.3
Gene Transfection
110
Acknowledgments
111
References
111
5
Interaction of
DNA
with Cationic Polymers
119
Eric Raspaud,
Adriana
С.
Toma,
Francoise Livolant,
and Joachim
Rädler
5.1
Introduction
119
5.2
Theory of
DNA
Interacting with Polycations
120
5.2.1
Manning Condensation
120
5.2.2
Counterion
Release
121
5.2.3
Short-Range Attractive Force due to Ion Correlations
121
5.2.4
Phase Diagrams of Condensed DNA-Polycation Phases
121
5.2.5
Finite-Size Aggregates
122
5.3
Condensation of
DNA,
Phase Diagram, and Structure
122
5.3.1
Short Polycations and Multivalent Cations
123
5.3.2
Long Polycations and Basic Proteins
123
5.4
Formation of Polycation-DNA Complexes: Polyplexes
125
5.5
DNA-Nanoparticles for Gene Delivery
126
5.5.1
Artificial Viruses
126
5.5.2
Cytotoxicity
127
5.6
Cellular Uptake and Intracellular Interactions of Polyplexes
127
5.7
Conclusion
129
Acknowledgment
129
References
129
6
Interactions of Histones with
DNA:
Nucleosome Assembly,
Stability, Dynamics, and Higher Order Structure
135
Karsten Rippe,
Jacek
Mazurkiewicz, and Nick Kepper
6.1
Introduction
135
6.2
Histones I36
6.2.1
Core Histones
136
6.2.2
Linker Histones
137
6.2.3
Histone Variants
138
6.2.4
Posttranslational Modifications of Histones
141
6.3
Structure of Histone-DNA Complexes
142
6.3.1
Nucleosome
142
6.3.2
Chromatosome I44
6.4
Assembly of Nucleosomes and Chromatosomes
144
6.4.1
Chaperone-Guided Nucleosome Assembly
146
VÍM
CONTENTS
6.4.2
Chromatin Remodeling Complexes
147
6.5
Stability and Dynamics of Nucleosomes
148
6.5.1
Accessibility of Nucleosomal
DNA 148
6.5.2 DNA
Sequence Specificity of Nucleosome Binding
149
6.5.3
Thermodynamic and Kinetic Parameters for
Nucleosome Formation under Physiological Conditions
150
6.6
Higher Order Chromatin Structures
154
6.6.1
Assembly of Chromatin Fibers
154
6.6.2
Higher Order Folding of Chromatin Fibers
157
Acknowledgments
158
References
158
7
Opening and Closing
DNA:
Theories on the Nucleosome
173
Igor M.
Kulić
and Helmut Schiessel
7.1
Introduction
173
7.2
Unwrapping Nucleosomes
176
7.3
Nucleosome Sliding
180
7.4
Transcription Through Nucleosomes
187
7.5
Tail Bridging
194
7.6
Discussion and Conclusion
202
Acknowledgment
204
References
204
8 DNA-DNA
Interactions
209
Lars
Nordenskiöld, Nikolay
Korolev, and Alexander P. Lyubartsev
8.1
Introduction
209
8.2
The Statistical Polymer Solution Model Predicts
DNA
Collapse/Aggregation Phase Behavior
211
8.3 DNA in
Solution is Condensed to a Compact State
by Multivalent Cationic Ligands
214
8.3.1 DNA
Compaction in Solution
214
8.3.2
Experimental Studies on Chromatin
and Nucleosome Condensation
219
8.3.3
Measurement of
DNA-DNA
Forces
from Osmotic Stress
221
8.4
Ion Correlation Effects Included in Theory and in
Computer Modeling Explain
DNA-DNA
Attraction
222
8.4.1
Analytical Theories of
DNA-DNA
Interactions
222
8.4.2
Computer Simulations of
DNA-DNA
Interactions
224
8.4.3
Modeling
DNA-DNA
Interactions in Chromatin and NCP
227
8.5
Conclusions and Future Prospects
230
References
231
CONTENTS
ІХ
9 Hydration
of DNA-Amphiphile Complexes
239
Cecilia
Leal and
Håkan Wennerström
9.1
Introduction
239
9.2
General
Properties of
DNA Double
Helices
and Cationic Aggregates 240
9.3
Thermodynamics of DNA-Amphiphile Complexes
243
9.4
Molecular Properties of DNA-Amphiphile Complexes
247
9.5
Concluding Remarks
249
References
250
10
DNA-Surfactant/Lipid Complexes at Liquid Interfaces
253
Dominique
Langevin
10.1
Introduction
253
10.2
Soluble Surfactants
255
10.2.1
DNA-DTAB Surface Layers
255
10.2.2
Other DNA-Cationic Surfactants Systems
261
10.2.3 DNA
Surfactants
262
10.3
Insoluble Surfactants
262
10.3.1
DNA-DODAB Surface Layers
263
10.3.2
DNA-TODAB Surface Layers
267
10.3.3
DNA-ODA Surface Layers
271
10.3.4 DNA
Binding with Other Surfactant Layers
273
10.4
Lipids
274
10.4.1
Cationic Lipids-DNA Surface Layers
275
10.4.2
DSPC-Divalent Ion-DNA Surface Layers
276
10.4.3
DPPC-Divalent Ion-DNA Surface Layers
278
10.4.4
DMPE-Divalent Ion-DNA Surface Layers
279
10.4.5
Other Types of Binding
283
10.5
Mixtures of Surfactants and Lipids
284
10.6
Conclusion
285
References
286
11 DNA
and DNA-Surfactant Complexes
at Solid Surfaces
291
Marité Cárdenas
and Tommy
Nyländer
11.1
Introduction
291
11.2
Adsorption of
DNA
at Surfaces
292
11.3
Attachment of
DNA
Surfaces—Strategies and Challenges
294
11.4 DNA
Structure on Surfaces
—
Comparison with Highly
Charged Polyelectrolytes
297
11.4.1
Regulating the
DNA
Compaction by Compaction
Agents at Interfaces to Control the Structure
297
X
CONTENTS
11.4.2
Cationic Surfactants and
DNA
at
Hydrophobie
Surfaces
298
11.4.3
Cationic Surfactants and
DNA
at Negatively
Charged Surfaces
304
11.5
Some Applications
—
Arrays and Nanostamping
307
Acknowledgments
310
References
310
12
Role of Correlation Forces for DNA-Cosolute Interactions
317
Malek O. Khan
12.1
Introduction
317
12.2
Experimental Evidence of
DNA
Condensation Induced
by Electrostatic Agents
317
12.3
Simulations Used to Characterize the
DNA
Compaction Mechanism
319
12.4
Ion Correlations Limiting the Validity of DLVO Theory
320
12.5
Ion Correlations Driving the Compaction of
DNA 322
12.6
Conformation of Compact
DNA—
The Coil to Toroid Transition
328
12.7
Conclusions
332
References
334
13
Simulations of Polyions: Compaction, Adsorption onto Surfaces,
and Confinement
337
A.A.C.
С.
Pais
and P.
Linse
13.1
Introduction
337
13.2
Models
339
13.3
Solutions of Polyions with Multivalent Counterions
340
13.3.1
Polyion Conformation
340
13.3.2
Small-Ion Distribution
341
13.3.3
Other Aspects
343
13.4
Polyion Adsorption onto Charged Surfaces
343
13.4.1
Surfaces with Homogeneous Surface Charge Densities
344
13.4.2
Surfaces with Heterogeneous Surface Charge Densities
344
13.5
Polyions in Confined Geometries
346
13.5.1
Structural Aspects
347
13.5.2
Free Energies
347
13.6
Concluding Remarks
349
References
349
14
Cross-linked
DNA Gels
and Gel Particles
353
Diana Costa, M. Carmen
Morón,
Maria G. Miguel, and
Björn Lindman
14.1
Introduction
353
CONTENTS
ХІ
14.2 Covalently
Cross-Linked
DNA Gels 354
14.2.1 Volumetrie
Behavior of
DNA Gel
Probes
DNA-Cosolute
Interactions
354
14.2.2
Swelling Reversibility
357
14.3 ds-DNA versus ss-DNA:
Skin
Formation 357
14.4 DNA Gel
Particles
358
14.4.1
Particle Characterization
358
14.4.2
Particle Swelling and
Deswelling
Kinetics
359
14.4.3
Kinetics of
DNA
Release
360
14.5
Physical
DNA Gels 361
14.5.1
Phase Behavior
361
14.5.2
Rheological Studies
362
References
363
15 DNA
as an Amphiphilic Polymer
367
Rita S.
Dias,
María
G.
Miguel, and
Björn Lindman
15.1
Some General Aspects of Self-Assembly
367
15.2
Illustrations
369
15.2.1
Solubilization of
Hydrophobie
Molecules in ds-DNA
370
15.2.2
Adsorption on
Hydrophobie
Surfaces
372
15.2.3
Effects of
Hydrophobie Cosolutes
on
DNA
Melting
372
15.2.4
Differences in Interactions (Phase Separation)
of Cationic Surfactants between ss-DNA and ds-DNA
373
15.2.5
DNA-Protein Interaction
374
15.2.6
Dependence of
DNA
Melting on Base Sequence
374
15.2.7 DNA
Physical and Chemical Gels
374
References
375
16
Lipid-DNA Interactions: Structure-Function Studies
of Nanomateriais for Gene Delivery
377
Kai
К.
Ewert, Charles E. Samuel, and Cyrus R. Safinya
16.1
Introduction
377
16.2
Formation and Structures of CL-DNA Complexes
378
16.3
Effect of the Lipid-DNA Charge Ratio (pcAg)
on CL-DNA Complex Properties
383
16.3.1
Physicochemical Effects and Phase Behavior
of CL-DNA Lipids
383
16.3.2
Biological Effects
386
16.4
Effect of the Membrane Charge Density
(σΜ)
on CL-DNA Complex Properties
387
16.5
Effect of Nonlamellar CL-DNA Complex Structure
on the Transfection Mechanism
391
XII CONTENTS
16.6
Model of Transfection with Lamellar CL-DNA Complexes
393
16.7
Model of Transfection with Inverted Hexagonal CL-DNA
Complexes
395
16.8
PEGylated CL-DNA Complexes: Surface Functionalization
and Distinct
DNA-DNA
Interaction Regimes
396
16.8.1 DNA-DNA
Interaction Regimes in PEG-Lipid
CL-DNA Complexes
396
16.8.2
Surface Functionalization of CL-DNA Complexes
with PEG-Lipids
397
16.9
Conclusion and Summary
400
Acknowledgments
400
References
401
Index
405
|
| adam_txt |
CONTENTS
Preface
xiii
Contributors
xv
1
Poiyelectrolytes. Phvsicochemical Aspects and Biological Significance
1
Magnus Ullner
1.1
Introduction
1
1.2
Poiyelectrolytes and Biological Function
1
1.3
Electrostatic Interactions
3
1.3.1
Ion Distributions and the Poisson-Boltzmann Equation
3
1.3.2
Debye-Hiickel Theory
9
1.4
Solution Properties
13
1.5
Flexibility
17
1.5.1
The Concept of Persistence Length
17
1.5.2
Interactions and the Separation of Length Scales
23
1.5.3
Polyelectrolyte Behavior: Electrostatic
Persistence Length
26
1.5.4 DNA
Persistence Length
29
References
31
2
Solution Behavior of Nucleic Acids
41
Rita S.
Dias
2.1
Biological Function of Nucleic Acids
41
2.2
Discovery of
DNA 41
2.3
Structure of Nucleic Acids
43
2.3.1 DNA 43
2.3.2
RNA
47
2.3.3
Analogues of Nucleic Acids
48
2.4
Nuclei Acids Nanostructures
48
2.4.1 DNA 48
2.4.2
RNA 50
2.5
Behavior of
DNA
in Solution 5
1
2.5.1
Ionization Equilibrium 51
2.5.2
Flexibility of Nucleic Acids
51
Vi
CONTENTS
2.6
Melting of Double-Stranded
DNA 52
2.6.1
Effect of Base Composition
53
2.6.2
Effect of Ionic Strength
53
2.6.3
Effect of
pH 53
2.6.4
Dependence on
DNA
Chain Length
54
2.6.5
Dependence on
DNA
Concentration
54
Acknowledgments
55
References
55
3
Single
DNA
Molecules: Compaction and Decompaction
59
Anatoly A. Zinchenko,
Olga
A. Pyshkina,
Andrey V. Lezov,
Vladimir G.
Sergeyev, and Kenichi Yoshikawa
3.1
Introduction
59
3.2
Condensation and Compaction of
DNA
by Surfactants
60
3.2.1
Linear
DNA
Condensation/Compaction
by Positively Charged Surfactants
60
3.2.2
Compaction of Plasmid
DNA
with Surfactants
63
3.2.3
Non-ionic Surfactants
64
3.2.4
Zwitterionic Surfactants
64
3.2.5
Decompaction of DNA-Surfactant Complex
65
3.3 DNA
Condensation by Cationic
Liposomes
65
3.4 DNA
Compaction and Decompaction by Multivalent Cations
74
3.5 DNA
Compaction by Polycations
77
3.6
Compaction of
DNA in
a Crowded Environment
of Neutral Polymer
81
3.7
Conclusion
82
References
82
4
Interaction of
DNA
with Surfactants in Solution
89
Rita S.
Dias,
Kenneth Dawson, and Maria G. Miguel
4.1
Introduction
89
4.1.1
Surfactants
89
4.1.2
Polymer-Surfactant Interactions
93
4.1.3
Polyelectrolyte-Oppositely Charged
Surfactant Interactions
94
4.1.4
DNA-Surfactant Interactions
95
4.2
DNA-Cationic Surfactant Interactions
96
4.2.1
Solution Behavior
96
4.2.2
Effect of the Surfactant Chain Length
99
4.2.3
Effect of the Surfactant Head-group
101
4.2.4
Structure of DNA-Surfactant Complexes
102
4.2.5 DNA
Is an Amphiphilic Polyelectrolyte
105
4.3 DNA
Covalent Gels and Their Interaction with Surfactants
106
CONTENTS
VII
4.4
Applications
108
4.4.1
Control of
DNA
Compaction/Decompaction
108
4.4.2
Purification
110
4.4.3
Gene Transfection
110
Acknowledgments
111
References
111
5
Interaction of
DNA
with Cationic Polymers
119
Eric Raspaud,
Adriana
С.
Toma,
Francoise Livolant,
and Joachim
Rädler
5.1
Introduction
119
5.2
Theory of
DNA
Interacting with Polycations
120
5.2.1
Manning Condensation
120
5.2.2
Counterion
Release
121
5.2.3
Short-Range Attractive Force due to Ion Correlations
121
5.2.4
Phase Diagrams of Condensed DNA-Polycation Phases
121
5.2.5
Finite-Size Aggregates
122
5.3
Condensation of
DNA,
Phase Diagram, and Structure
122
5.3.1
Short Polycations and Multivalent Cations
123
5.3.2
Long Polycations and Basic Proteins
123
5.4
Formation of Polycation-DNA Complexes: Polyplexes
125
5.5
DNA-Nanoparticles for Gene Delivery
126
5.5.1
Artificial Viruses
126
5.5.2
Cytotoxicity
127
5.6
Cellular Uptake and Intracellular Interactions of Polyplexes
127
5.7
Conclusion
129
Acknowledgment
129
References
129
6
Interactions of Histones with
DNA:
Nucleosome Assembly,
Stability, Dynamics, and Higher Order Structure
135
Karsten Rippe,
Jacek
Mazurkiewicz, and Nick Kepper
6.1
Introduction
135
6.2
Histones I36
6.2.1
Core Histones
136
6.2.2
Linker Histones
137
6.2.3
Histone Variants
138
6.2.4
Posttranslational Modifications of Histones
141
6.3
Structure of Histone-DNA Complexes
142
6.3.1
Nucleosome
142
6.3.2
Chromatosome I44
6.4
Assembly of Nucleosomes and Chromatosomes
144
6.4.1
Chaperone-Guided Nucleosome Assembly
146
VÍM
CONTENTS
6.4.2
Chromatin Remodeling Complexes
147
6.5
Stability and Dynamics of Nucleosomes
148
6.5.1
Accessibility of Nucleosomal
DNA 148
6.5.2 DNA
Sequence Specificity of Nucleosome Binding
149
6.5.3
Thermodynamic and Kinetic Parameters for
Nucleosome Formation under Physiological Conditions
150
6.6
Higher Order Chromatin Structures
154
6.6.1
Assembly of Chromatin Fibers
154
6.6.2
Higher Order Folding of Chromatin Fibers
157
Acknowledgments
158
References
158
7
Opening and Closing
DNA:
Theories on the Nucleosome
173
Igor M.
Kulić
and Helmut Schiessel
7.1
Introduction
173
7.2
Unwrapping Nucleosomes
176
7.3
Nucleosome Sliding
180
7.4
Transcription Through Nucleosomes
187
7.5
Tail Bridging
194
7.6
Discussion and Conclusion
202
Acknowledgment
204
References
204
8 DNA-DNA
Interactions
209
Lars
Nordenskiöld, Nikolay
Korolev, and Alexander P. Lyubartsev
8.1
Introduction
209
8.2
The Statistical Polymer Solution Model Predicts
DNA
Collapse/Aggregation Phase Behavior
211
8.3 DNA in
Solution is Condensed to a Compact State
by Multivalent Cationic Ligands
214
8.3.1 DNA
Compaction in Solution
214
8.3.2
Experimental Studies on Chromatin
and Nucleosome Condensation
219
8.3.3
Measurement of
DNA-DNA
Forces
from Osmotic Stress
221
8.4
Ion Correlation Effects Included in Theory and in
Computer Modeling Explain
DNA-DNA
Attraction
222
8.4.1
Analytical Theories of
DNA-DNA
Interactions
222
8.4.2
Computer Simulations of
DNA-DNA
Interactions
224
8.4.3
Modeling
DNA-DNA
Interactions in Chromatin and NCP
227
8.5
Conclusions and Future Prospects
230
References
231
CONTENTS
ІХ
9 Hydration
of DNA-Amphiphile Complexes
239
Cecilia
Leal and
Håkan Wennerström
9.1
Introduction
239
9.2
General
Properties of
DNA Double
Helices
and Cationic Aggregates 240
9.3
Thermodynamics of DNA-Amphiphile Complexes
243
9.4
Molecular Properties of DNA-Amphiphile Complexes
247
9.5
Concluding Remarks
249
References
250
10
DNA-Surfactant/Lipid Complexes at Liquid Interfaces
253
Dominique
Langevin
10.1
Introduction
253
10.2
Soluble Surfactants
255
10.2.1
DNA-DTAB Surface Layers
255
10.2.2
Other DNA-Cationic Surfactants Systems
261
10.2.3 DNA
Surfactants
262
10.3
Insoluble Surfactants
262
10.3.1
DNA-DODAB Surface Layers
263
10.3.2
DNA-TODAB Surface Layers
267
10.3.3
DNA-ODA Surface Layers
271
10.3.4 DNA
Binding with Other Surfactant Layers
273
10.4
Lipids
274
10.4.1
Cationic Lipids-DNA Surface Layers
275
10.4.2
DSPC-Divalent Ion-DNA Surface Layers
276
10.4.3
DPPC-Divalent Ion-DNA Surface Layers
278
10.4.4
DMPE-Divalent Ion-DNA Surface Layers
279
10.4.5
Other Types of Binding
283
10.5
Mixtures of Surfactants and Lipids
284
10.6
Conclusion
285
References
286
11 DNA
and DNA-Surfactant Complexes
at Solid Surfaces
291
Marité Cárdenas
and Tommy
Nyländer
11.1
Introduction
291
11.2
Adsorption of
DNA
at Surfaces
292
11.3
Attachment of
DNA
Surfaces—Strategies and Challenges
294
11.4 DNA
Structure on Surfaces
—
Comparison with Highly
Charged Polyelectrolytes
297
11.4.1
Regulating the
DNA
Compaction by Compaction
Agents at Interfaces to Control the Structure
297
X
CONTENTS
11.4.2
Cationic Surfactants and
DNA
at
Hydrophobie
Surfaces
298
11.4.3
Cationic Surfactants and
DNA
at Negatively
Charged Surfaces
304
11.5
Some Applications
—
Arrays and Nanostamping
307
Acknowledgments
310
References
310
12
Role of Correlation Forces for DNA-Cosolute Interactions
317
Malek O. Khan
12.1
Introduction
317
12.2
Experimental Evidence of
DNA
Condensation Induced
by Electrostatic Agents
317
12.3
Simulations Used to Characterize the
DNA
Compaction Mechanism
319
12.4
Ion Correlations Limiting the Validity of DLVO Theory
320
12.5
Ion Correlations Driving the Compaction of
DNA 322
12.6
Conformation of Compact
DNA—
The Coil to Toroid Transition
328
12.7
Conclusions
332
References
334
13
Simulations of Polyions: Compaction, Adsorption onto Surfaces,
and Confinement
337
A.A.C.
С.
Pais
and P.
Linse
13.1
Introduction
337
13.2
Models
339
13.3
Solutions of Polyions with Multivalent Counterions
340
13.3.1
Polyion Conformation
340
13.3.2
Small-Ion Distribution
341
13.3.3
Other Aspects
343
13.4
Polyion Adsorption onto Charged Surfaces
343
13.4.1
Surfaces with Homogeneous Surface Charge Densities
344
13.4.2
Surfaces with Heterogeneous Surface Charge Densities
344
13.5
Polyions in Confined Geometries
346
13.5.1
Structural Aspects
347
13.5.2
Free Energies
347
13.6
Concluding Remarks
349
References
349
14
Cross-linked
DNA Gels
and Gel Particles
353
Diana Costa, M. Carmen
Morón,
Maria G. Miguel, and
Björn Lindman
14.1
Introduction
353
CONTENTS
ХІ
14.2 Covalently
Cross-Linked
DNA Gels 354
14.2.1 Volumetrie
Behavior of
DNA Gel
Probes
DNA-Cosolute
Interactions
354
14.2.2
Swelling Reversibility
357
14.3 ds-DNA versus ss-DNA:
Skin
Formation 357
14.4 DNA Gel
Particles
358
14.4.1
Particle Characterization
358
14.4.2
Particle Swelling and
Deswelling
Kinetics
359
14.4.3
Kinetics of
DNA
Release
360
14.5
Physical
DNA Gels 361
14.5.1
Phase Behavior
361
14.5.2
Rheological Studies
362
References
363
15 DNA
as an Amphiphilic Polymer
367
Rita S.
Dias,
María
G.
Miguel, and
Björn Lindman
15.1
Some General Aspects of Self-Assembly
367
15.2
Illustrations
369
15.2.1
Solubilization of
Hydrophobie
Molecules in ds-DNA
370
15.2.2
Adsorption on
Hydrophobie
Surfaces
372
15.2.3
Effects of
Hydrophobie Cosolutes
on
DNA
Melting
372
15.2.4
Differences in Interactions (Phase Separation)
of Cationic Surfactants between ss-DNA and ds-DNA
373
15.2.5
DNA-Protein Interaction
374
15.2.6
Dependence of
DNA
Melting on Base Sequence
374
15.2.7 DNA
Physical and Chemical Gels
374
References
375
16
Lipid-DNA Interactions: Structure-Function Studies
of Nanomateriais for Gene Delivery
377
Kai
К.
Ewert, Charles E. Samuel, and Cyrus R. Safinya
16.1
Introduction
377
16.2
Formation and Structures of CL-DNA Complexes
378
16.3
Effect of the Lipid-DNA Charge Ratio (pcAg)
on CL-DNA Complex Properties
383
16.3.1
Physicochemical Effects and Phase Behavior
of CL-DNA Lipids
383
16.3.2
Biological Effects
386
16.4
Effect of the Membrane Charge Density
(σΜ)
on CL-DNA Complex Properties
387
16.5
Effect of Nonlamellar CL-DNA Complex Structure
on the Transfection Mechanism
391
XII CONTENTS
16.6
Model of Transfection with Lamellar CL-DNA Complexes
393
16.7
Model of Transfection with Inverted Hexagonal CL-DNA
Complexes
395
16.8
PEGylated CL-DNA Complexes: Surface Functionalization
and Distinct
DNA-DNA
Interaction Regimes
396
16.8.1 DNA-DNA
Interaction Regimes in PEG-Lipid
CL-DNA Complexes
396
16.8.2
Surface Functionalization of CL-DNA Complexes
with PEG-Lipids
397
16.9
Conclusion and Summary
400
Acknowledgments
400
References
401
Index
405 |
| any_adam_object | 1 |
| any_adam_object_boolean | 1 |
| author_GND | (DE-588)135798906 |
| building | Verbundindex |
| bvnumber | BV023400686 |
| callnumber-first | Q - Science |
| callnumber-label | QP624 |
| callnumber-raw | QP624 |
| callnumber-search | QP624 |
| callnumber-sort | QP 3624 |
| callnumber-subject | QP - Physiology |
| classification_rvk | WD 5360 |
| ctrlnum | (OCoLC)181862648 (DE-599)GBV550562540 |
| dewey-full | 572.8/6 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 572 - Biochemistry |
| dewey-raw | 572.8/6 |
| dewey-search | 572.8/6 |
| dewey-sort | 3572.8 16 |
| dewey-tens | 570 - Biology |
| discipline | Biologie |
| discipline_str_mv | Biologie |
| format | Book |
| fullrecord | <?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>02211nam a2200565zc 4500</leader><controlfield tag="001">BV023400686</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20080808 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">080717s2008 xxua||| |||| 00||| eng d</controlfield><datafield tag="010" ind1=" " ind2=" "><subfield code="a">2007046844</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780470258187</subfield><subfield code="c">cloth</subfield><subfield code="9">978-0-470-25818-7</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)181862648</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)GBV550562540</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">aacr</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="a">xxu</subfield><subfield code="c">US</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-703</subfield><subfield code="a">DE-11</subfield></datafield><datafield tag="050" ind1=" " ind2="0"><subfield code="a">QP624</subfield></datafield><datafield tag="082" ind1="0" ind2=" "><subfield code="a">572.8/6</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WD 5360</subfield><subfield code="0">(DE-625)148202:</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">DNA interactions with polymers and surfactants</subfield><subfield code="c">edited by Rita Dias and Björn Lindman</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Hoboken, N.J.</subfield><subfield code="b">John Wiley</subfield><subfield code="c">c2008</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">xviii, 407 p.</subfield><subfield code="b">ill.</subfield><subfield code="c">25 cm</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="500" ind1=" " ind2=" "><subfield code="a">Includes bibliographical references and index</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">DNA</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Polymers</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Surface active agents</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">DNA</subfield><subfield code="x">chemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Polymers</subfield><subfield code="x">chemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Solutions</subfield><subfield code="x">chemistry</subfield></datafield><datafield tag="650" ind1=" " ind2="4"><subfield code="a">Surface-Active Agents</subfield><subfield code="x">chemistry</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Oberflächenchemie</subfield><subfield code="0">(DE-588)4126166-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Polymere</subfield><subfield code="0">(DE-588)4046699-1</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">DNS</subfield><subfield code="0">(DE-588)4070512-2</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">DNS</subfield><subfield code="0">(DE-588)4070512-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Polymere</subfield><subfield code="0">(DE-588)4046699-1</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="689" ind1="1" ind2="0"><subfield code="a">DNS</subfield><subfield code="0">(DE-588)4070512-2</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2="1"><subfield code="a">Oberflächenchemie</subfield><subfield code="0">(DE-588)4126166-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="1" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Dias, Rita</subfield><subfield code="e">Sonstige</subfield><subfield code="0">(DE-588)135798906</subfield><subfield code="4">oth</subfield></datafield><datafield tag="856" ind1="4" ind2=" "><subfield code="u">http://www.loc.gov/catdir/enhancements/fy0805/2007046844-d.html</subfield><subfield code="3">Publisher description</subfield></datafield><datafield tag="856" ind1="4" ind2=" "><subfield code="u">http://www.loc.gov/catdir/enhancements/fy0805/2007046844-t.html</subfield><subfield code="3">Table of contents only</subfield></datafield><datafield tag="856" ind1="4" ind2=" "><subfield code="u">http://www.loc.gov/catdir/enhancements/fy0827/2007046844-b.html</subfield><subfield code="3">Contributor biographical information</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Digitalisierung UB Bayreuth</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016583480&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-016583480</subfield></datafield></record></collection> |
| id | DE-604.BV023400686 |
| illustrated | Illustrated |
| index_date | 2024-07-02T21:23:37Z |
| indexdate | 2024-07-09T21:17:47Z |
| institution | BVB |
| isbn | 9780470258187 |
| language | English |
| lccn | 2007046844 |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-016583480 |
| oclc_num | 181862648 |
| open_access_boolean | |
| owner | DE-703 DE-11 |
| owner_facet | DE-703 DE-11 |
| physical | xviii, 407 p. ill. 25 cm |
| publishDate | 2008 |
| publishDateSearch | 2008 |
| publishDateSort | 2008 |
| publisher | John Wiley |
| record_format | marc |
| spelling | DNA interactions with polymers and surfactants edited by Rita Dias and Björn Lindman Hoboken, N.J. John Wiley c2008 xviii, 407 p. ill. 25 cm txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index DNA Polymers Surface active agents DNA chemistry Polymers chemistry Solutions chemistry Surface-Active Agents chemistry Oberflächenchemie (DE-588)4126166-5 gnd rswk-swf Polymere (DE-588)4046699-1 gnd rswk-swf DNS (DE-588)4070512-2 gnd rswk-swf DNS (DE-588)4070512-2 s Polymere (DE-588)4046699-1 s DE-604 Oberflächenchemie (DE-588)4126166-5 s Dias, Rita Sonstige (DE-588)135798906 oth http://www.loc.gov/catdir/enhancements/fy0805/2007046844-d.html Publisher description http://www.loc.gov/catdir/enhancements/fy0805/2007046844-t.html Table of contents only http://www.loc.gov/catdir/enhancements/fy0827/2007046844-b.html Contributor biographical information Digitalisierung UB Bayreuth application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016583480&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | DNA interactions with polymers and surfactants DNA Polymers Surface active agents DNA chemistry Polymers chemistry Solutions chemistry Surface-Active Agents chemistry Oberflächenchemie (DE-588)4126166-5 gnd Polymere (DE-588)4046699-1 gnd DNS (DE-588)4070512-2 gnd |
| subject_GND | (DE-588)4126166-5 (DE-588)4046699-1 (DE-588)4070512-2 |
| title | DNA interactions with polymers and surfactants |
| title_auth | DNA interactions with polymers and surfactants |
| title_exact_search | DNA interactions with polymers and surfactants |
| title_exact_search_txtP | DNA interactions with polymers and surfactants |
| title_full | DNA interactions with polymers and surfactants edited by Rita Dias and Björn Lindman |
| title_fullStr | DNA interactions with polymers and surfactants edited by Rita Dias and Björn Lindman |
| title_full_unstemmed | DNA interactions with polymers and surfactants edited by Rita Dias and Björn Lindman |
| title_short | DNA interactions with polymers and surfactants |
| title_sort | dna interactions with polymers and surfactants |
| topic | DNA Polymers Surface active agents DNA chemistry Polymers chemistry Solutions chemistry Surface-Active Agents chemistry Oberflächenchemie (DE-588)4126166-5 gnd Polymere (DE-588)4046699-1 gnd DNS (DE-588)4070512-2 gnd |
| topic_facet | DNA Polymers Surface active agents DNA chemistry Polymers chemistry Solutions chemistry Surface-Active Agents chemistry Oberflächenchemie Polymere DNS |
| url | http://www.loc.gov/catdir/enhancements/fy0805/2007046844-d.html http://www.loc.gov/catdir/enhancements/fy0805/2007046844-t.html http://www.loc.gov/catdir/enhancements/fy0827/2007046844-b.html http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016583480&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT diasrita dnainteractionswithpolymersandsurfactants |