Defining optimal immunotherapies for type 1 diabetes:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Chichester [u.a.]
Wiley
2008
|
| Series: | Novartis Foundation symposium
292 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | IX, 212 S. Ill., graph. Darst. |
| ISBN: | 9780470723258 |
Staff View
MARC
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Record in the Search Index
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| adam_text | Contents
Novartis Foundation Symposium on Defining optimal immunotherapies for type 1 diabetes,
held at The Novartis Foundation, London, 11-12 July 2007
Editors: Gregory Bock (Organiser) and Jamie Goode
This symposium is based on a proposal made by Matthias von Herrath and
Jeffrey Bluestone
Matthias von Herrath Chair s introduction 1
Alan K. Foulis Pancreatic pathology in type 1 diabetes in human 2
Discussion 13
Daniel Pipeleers, Peter In t Veld, Miriam Pipeleers-Marichal and
Frans Gorus The p cell population in type 1 diabetes 19
Discussion 24
Peter Reifsnyder, William Schott, Darcy Pomerleau, Mark D. Lessard,
Brian W. Soper and Edward H. Leiter Bone marrow expressing a
diabetes resistance MHC class II allele: diabetes deviation by chronic
immune stimulation 32
Discussion 46
1 • - c
Damien Bresson and Matthias von Herrath Resuscitating adaptive
Tregs with combination therapies? 50
Discussion 60
Thomas W. H. Kay, Nadine L. Dudek, Kate Graham, Eugene Estella,
Eveline Angstetra, Mark D. McKenzie, Jan Allison and
Helen E. Thomas Cytotoxic T cell mechanisms of p cell destruction in
non-obese diabetic mice 68
Discussion 78
v
vi CONTENTS
Li Zhang, Roberto Gianani, Maki Nakayama, Edwin Liu, Masakazu
Kobayashi, Erin Baschal, Liping Yu, Sunanda Babu, Abby Dawson,
Kelly Johnson, Mohamed Jahromi, Theresa Aly, Pamela Fain,
Jennifer Barker, Marian Rewers and George S. Eisenbarth
Type 1 diabetes: chronic progressive autoimmune disease 85
Discussion 94
Teodora Staeva Current and past prevention and intervention trials
in type 1 diabetes 99
Discussion 109
Mark Peakman CD8 and cytotoxic T cells in type 1 diabetes 113
Discussion 119
General discussion I 122
General discussion II 126
Pere Santamaria Genetic and therapeutic control of diabetogenic
CD8+ T cells 130
Discussion 136
General discussion III 141
Frank Waldron-Lynch, Matthias von Herrath and Kevan C.
Herold Towards a curative therapy in type 1 diabetes:
remission of autoimmunity, maintenance and augmentation of
P cell mass 146
Discussion 155
Bart O. Roep Immune markers of disease and therapeutic intervention
in type 1 diabetes 159
Discussion 171
Silvia Gregori, Manuela Battaglia and Maria-Grazia Roncarolo
Re-establishing immune tolerance in type 1 diabetes via regulatory
T cells 174
Discussion 183
CONTENTS vii
Ezio Bonifacio, Anette Ziegler, Peter Achenbach, Jennifer Barker
and George S. Eisenbarth Translating mucosal antigen based prevention
of autoimmune diabetes to human 187
Discussion 199
Matthias von Herrath Closing remarks 202
Index of contributors 204
Subject index 206
|
| adam_txt |
Contents
Novartis Foundation Symposium on Defining optimal immunotherapies for type 1 diabetes,
held at The Novartis Foundation, London, 11-12 July 2007
Editors: Gregory Bock (Organiser) and Jamie Goode
This symposium is based on a proposal made by Matthias von Herrath and
Jeffrey Bluestone
Matthias von Herrath Chair's introduction 1
Alan K. Foulis Pancreatic pathology in type 1 diabetes in human 2
Discussion 13
Daniel Pipeleers, Peter In 't Veld, Miriam Pipeleers-Marichal and
Frans Gorus The p cell population in type 1 diabetes 19
Discussion 24
Peter Reifsnyder, William Schott, Darcy Pomerleau, Mark D. Lessard,
Brian W. Soper and Edward H. Leiter Bone marrow expressing a
diabetes resistance MHC class II allele: diabetes deviation by chronic
immune stimulation 32
Discussion 46
1 • - c
Damien Bresson and Matthias von Herrath Resuscitating adaptive
Tregs with combination therapies? 50
Discussion 60
Thomas W. H. Kay, Nadine L. Dudek, Kate Graham, Eugene Estella,
Eveline Angstetra, Mark D. McKenzie, Jan Allison and
Helen E. Thomas Cytotoxic T cell mechanisms of p cell destruction in
non-obese diabetic mice 68
Discussion 78
v
vi CONTENTS
Li Zhang, Roberto Gianani, Maki Nakayama, Edwin Liu, Masakazu
Kobayashi, Erin Baschal, Liping Yu, Sunanda Babu, Abby Dawson,
Kelly Johnson, Mohamed Jahromi, Theresa Aly, Pamela Fain,
Jennifer Barker, Marian Rewers and George S. Eisenbarth
Type 1 diabetes: chronic progressive autoimmune disease 85
Discussion 94
Teodora Staeva Current and past prevention and intervention trials
in type 1 diabetes 99
Discussion 109
Mark Peakman CD8 and cytotoxic T cells in type 1 diabetes 113
Discussion 119
General discussion I 122
General discussion II 126
Pere Santamaria Genetic and therapeutic control of diabetogenic
CD8+ T cells 130
Discussion 136
General discussion III 141
Frank Waldron-Lynch, Matthias von Herrath and Kevan C.
Herold Towards a curative therapy in type 1 diabetes:
remission of autoimmunity, maintenance and augmentation of
P cell mass 146
Discussion 155
Bart O. Roep Immune markers of disease and therapeutic intervention
in type 1 diabetes 159
Discussion 171
Silvia Gregori, Manuela Battaglia and Maria-Grazia Roncarolo
Re-establishing immune tolerance in type 1 diabetes via regulatory
T cells 174
Discussion 183
CONTENTS vii
Ezio Bonifacio, Anette Ziegler, Peter Achenbach, Jennifer Barker
and George S. Eisenbarth Translating mucosal antigen based prevention
of autoimmune diabetes to human 187
Discussion 199
Matthias von Herrath Closing remarks 202
Index of contributors 204
Subject index 206 |
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| illustrated | Illustrated |
| index_date | 2024-07-02T21:13:40Z |
| indexdate | 2024-07-09T21:17:08Z |
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| isbn | 9780470723258 |
| language | English |
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| physical | IX, 212 S. Ill., graph. Darst. |
| publishDate | 2008 |
| publishDateSearch | 2008 |
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| publisher | Wiley |
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| series | Novartis Foundation symposium |
| series2 | Novartis Foundation symposium |
| spelling | Defining optimal immunotherapies for type 1 diabetes Chichester [u.a.] Wiley 2008 IX, 212 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Novartis Foundation symposium 292 Diabetes Mellitus, Type 1 therapy Congresses Diabetes Immunotherapy Congresses Immuntherapie (DE-588)4026640-0 gnd rswk-swf Autoimmunität (DE-588)4319435-7 gnd rswk-swf Diabetes mellitus Typ 1 (DE-588)1194595685 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2007 London gnd-content Diabetes mellitus Typ 1 (DE-588)1194595685 s Autoimmunität (DE-588)4319435-7 s DE-604 Immuntherapie (DE-588)4026640-0 s b DE-604 Novartis Foundation symposium 292 (DE-604)BV011990857 292 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016557224&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Defining optimal immunotherapies for type 1 diabetes Novartis Foundation symposium Diabetes Mellitus, Type 1 therapy Congresses Diabetes Immunotherapy Congresses Immuntherapie (DE-588)4026640-0 gnd Autoimmunität (DE-588)4319435-7 gnd Diabetes mellitus Typ 1 (DE-588)1194595685 gnd |
| subject_GND | (DE-588)4026640-0 (DE-588)4319435-7 (DE-588)1194595685 (DE-588)1071861417 |
| title | Defining optimal immunotherapies for type 1 diabetes |
| title_auth | Defining optimal immunotherapies for type 1 diabetes |
| title_exact_search | Defining optimal immunotherapies for type 1 diabetes |
| title_exact_search_txtP | Defining optimal immunotherapies for type 1 diabetes |
| title_full | Defining optimal immunotherapies for type 1 diabetes |
| title_fullStr | Defining optimal immunotherapies for type 1 diabetes |
| title_full_unstemmed | Defining optimal immunotherapies for type 1 diabetes |
| title_short | Defining optimal immunotherapies for type 1 diabetes |
| title_sort | defining optimal immunotherapies for type 1 diabetes |
| topic | Diabetes Mellitus, Type 1 therapy Congresses Diabetes Immunotherapy Congresses Immuntherapie (DE-588)4026640-0 gnd Autoimmunität (DE-588)4319435-7 gnd Diabetes mellitus Typ 1 (DE-588)1194595685 gnd |
| topic_facet | Diabetes Mellitus, Type 1 therapy Congresses Diabetes Immunotherapy Congresses Immuntherapie Autoimmunität Diabetes mellitus Typ 1 Konferenzschrift 2007 London |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016557224&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV011990857 |