Verfügbarkeit: Neuroimmunology of sleep

Neuroimmunology of sleep:

Gespeichert in:

Bibliographische Detailangaben
Format:	Buch
Sprache:	English
Veröffentlicht:	Dordrecht Springer 2007
Schlagworte:	Neuroimmunologie Schlaf
Online-Zugang:	Inhaltsverzeichnis
Beschreibung:	XXI, 361 S. Ill., graph. Darst.
ISBN:	0387691448 9780387691442

Internformat

MARC


LEADER	00000nam a2200000 c 4500
001	BV023335277
003	DE-604
005	20170912
007	t
008	080609s2007 gw ad\|\| \|\|\|\| 00\|\|\| eng d
015			\|a 07,N02,0786 \|2 dnb
020			\|a 0387691448 \|c Gb. (Pr. in Vorb.) \|9 0-387-69144-8
020			\|a 9780387691442 \|c Gb. (Pr. in Vorb.) \|9 978-0-387-69144-2
024	3		\|a 9780387691442
035			\|a (OCoLC)633646828
035			\|a (DE-599)BVBBV023335277
040			\|a DE-604 \|b ger \|e rakddb
041	0		\|a eng
044			\|a gw \|c XA-DE-BE
049			\|a DE-355
084			\|a WX 3350 \|0 (DE-625)152192:13423 \|2 rvk
084			\|a YH 4222 \|0 (DE-625)153542:12928 \|2 rvk
084			\|a 610 \|2 sdnb
245	1	0	\|a Neuroimmunology of sleep \|c S. R. Pandi-Perumal ; Daniel P. Cardinali ; George P. Chrousos
264		1	\|a Dordrecht \|b Springer \|c 2007
300			\|a XXI, 361 S. \|b Ill., graph. Darst.
336			\|b txt \|2 rdacontent
337			\|b n \|2 rdamedia
338			\|b nc \|2 rdacarrier
650	0	7	\|a Neuroimmunologie \|0 (DE-588)4115376-5 \|2 gnd \|9 rswk-swf
650	0	7	\|a Schlaf \|0 (DE-588)4052580-6 \|2 gnd \|9 rswk-swf
689	0	0	\|a Schlaf \|0 (DE-588)4052580-6 \|D s
689	0	1	\|a Neuroimmunologie \|0 (DE-588)4115376-5 \|D s
689	0		\|5 DE-604
700	1		\|a Pandi-Perumal, Seithikurippu R. \|d 1964- \|e Sonstige \|0 (DE-588)131380419 \|4 oth
700	1		\|a Cardinali, Daniel P. \|e Sonstige \|4 oth
700	1		\|a Chrousos, George P. \|e Sonstige \|4 oth
776	0	8	\|i Erscheint auch als \|n Online-Ausgabe \|z 0-387-69146-4
776	0	8	\|i Erscheint auch als \|n Online-Ausgabe \|z 978-0-387-69146-6
856	4	2	\|m Digitalisierung UB Regensburg \|q application/pdf \|u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016519154&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA \|3 Inhaltsverzeichnis
999			\|a oai:aleph.bib-bvb.de:BVB01-016519154

Datensatz im Suchindex

_version_	1804137685405663232
adam_text	Contents Preface ......................................................................................................................xiii Acknowledgments .....................................................................................................xv Contributors ...........................................................................................................xvii Part I General Concepts .........................................................................................1 1. Bidirectional Communication Between the Brain and the Immune System .....................................................................................................................3 Douglas A. Weigent and J. Edwin Blalock 1.1 Introduction ....................................................................................................3 1.2 Nervous System Communication to the Immune System ..............................6 1.3 Neuroendocrine Hormone Influence on the Immune System ........................8 1.4 Actions of Hypothalamic Releasing Hormones ...........................................10 1.5 Immune System Communication with the Nervous System Hormones .....................................................................................................11 1.6 Cytokine Influences on the Nervous System ...............................................12 1.7 Neuroendocrine Hormone Release by Cells of the Immune System ...........14 1.8 Neurotransmitter Release by Cells of the Immune System .........................16 1.9 Bidirectional Communication and Sleep ......................................................17 1.10 Summary and Conclusions ...........................................................................17 2. Neuroimmunological Correlates of Circadian Rhythmicity in Oral Biology and Medicine ..........................................................................................27 Francesco Chiappelli, Olivia S. Cajulis, Audrey Navarro and David R. Moradi 2.1 Introduction ..................................................................................................27 vi Contents 2.2 Allostatic Response and Allostatic Intervention: Relevance to Oral Biology and Medicine ..................................................................................29 2.2.1 Allostasis .........................................................................................29 2.2.2 Allostatic Load ...............................................................................30 2.2.3 Allostatic Testing and Intervention ................................................32 2.2.4 Allostasis Is Not Chaos - or Is It? ..................................................34 2.3 Mucositis: A Case of Allostatic Load .........................................................36 2.3.1 Oral Mucositis .................................................................................36 2.3.2 Neuroendocrine-Immune Orderly Chaos in OM ............................39 2.3.3 Circadian Neurobiology and Neuroimmunopathology in OM ...................................................................................................46 2.4 Directions for the Future .............................................................................49 3. Circadian Organization of the Immune Response: Lessons from the Adjuvant Arthritis Model ..................................................................................59 Daniel P. Cardinali, Ana I. Esquifino, Georges J. M. Maestroni and Seithikurippu R. Pandi-Perumal 3.1 The Circadian Clock is One of the most Indispensable Biological Functions ......................................................................................................59 3.2 The Immune System Shows Circadian Organization ..................................61 3.3 Sickness Behavior Includes Changes in Circadian Rhythms ...................64 3.4 The Rat Adjuvant Arthritis is an Experimental Model of Rheumatoid Arthritis ....................................................................................66 3.5 Adjuvant Arthritis Disrupts Normal Chronobiological Organization .................................................................................................68 3.6 Melatonin as a Circadian Immunoregulatory Signal in Adjuvant Arthritis .........................................................................................................72 Part II Basic Research ............................................................................................85 4. The Biological Clock in Inflammation and Sleep Switch Alterations ............87 Marina Bentivoglio, Mikael Nygård, Maria Palomba and Krister Kristensson 4.1 Introduction ..................................................................................................87 4.2 Interactions Between the Biological Clock and the Sleep Switch ...............87 4.3 Effects of Inflammatory Molecules on the SCN and Sleep Switch Structures ......................................................................................................90 4.4 Intracellular Inflammatory Regulators .........................................................92 4.4.1 SHP. PIAS, and SOCS ...................................................................92 4.4.2 Intracellular Regulation of Inflammation and the Biological Clock ..............................................................................92 4.5 Concluding Remarks ...................................................................................94 5. Vasoaetive Intestinal Polypeptide and Prolactin Cytokines: Role in Sleep and Some Immune Aspects .....................................................................97 Fabio Garcia-Garcia, Tatiana Olivares-Bamielos and René Drucker- Colin Contents vii 5.1 Introduction ..................................................................................................97 5.2 Vasoactive Intestinal Polypeptide (VIP) ..................................................... 98 5.2.1 Receptors ........................................................................................98 5.2.2 Gene Regulation ..............................................................................98 5.3 VIP: Brain Distribution ................................................................................99 5.4 VIP and Sleep Regulation ............................................................................99 5.5 How VIP Induces REMS: a Hypothesis ....................................................102 5.6 VIP Clinical Implications ...........................................................................102 5.7 Prolactin (PRL) ..........................................................................................103 5.8 PRL Molecular Aspects ..............................................................................103 5.8.1 Gene Regulation ...........................................................................104 5.8.2 Posttranslational Modifications ....................................................104 5.9 PRL and Sleep Regulation .........................................................................105 5.10 Relationship Between PRL and Stress ......................................................107 5.11 Stress and REMS: Role of PRL .................................................................108 5.12 PRL Expression and REMS .......................................................................109 5.13 PRL Clinical Implications ..........................................................................109 6. Immune Signaling to Brain: Mechanisms and Potential Pathways Influencing Sleep ...............................................................................................119 Lisa Goehler and Ronald Gaykema 6.1 Introduction ................................................................................................119 6.2 Mechanisms of Immune Signaling to the Brain .........................................119 6.2.1 Neural Pathways ............................................................................119 6.2.2 Endocrine-Like Pathways: Immune Sensing within the Brain ..............................................................................................122 6.3 Neurocircuitry Mediating Sleep and Waking States ..................................124 6.4 What are the Links Between Immune-Brain Interfaces and Sleep Neurocircuitry? ...........................................................................................124 6.4.1 Primary Sensory Relay Nuclei ......................................................126 6.4.2 Ascending Pathways Influencing Arousal ....................................127 6.5 Conclusions and Perspectives ....................................................................127 7. Aging, Sleep, and Immunity .............................................................................133 Laura-Yvette Gorczynski, Ender Terzioglu, Thierry Waelli and R.M. Gorczynski 7.1 Introduction ................................................................................................133 7.2 Altered Sleep and Concomitant Alterations in Immune Function .............133 7.3 Cytokines and Sleep ...................................................................................135 7.4 Relationship of Infection to Altered Sleep Behavior .................................138 7.5 Stress. Hormonal Change, Cytokines. and Sleep Behavior .......................140 7.6 Age-Related Changes in Sleep and Relation to Altered Immunity ............143 7.7 Summary and Conclusions .........................................................................148 8. Cytokines and Sleep: Neuro-immune Interactions and Regulations ...........155 Tetsuya Kushikata, Hiwshi Yoshidu and Tadanobu Yasuda 8.1 introduction ................................................................................................155 8.2 Effect of Sleep on Immune System ............................................................155 viii Contents 8.2.1 Sleep Pattern and Immune Function ............................................155 8.2.2 Sleep Deprivation and Immune System .......................................156 8.3 Effect of Modulation of Immune System on Sleep ...................................156 8.3.1 Overview ......................................................................................156 8.3.2 Microbial Products, Cytokines, Sleep ..........................................157 8.3.3 Proinflammatory Cytokines on Sleep ..........................................157 8.3.4 Anti-Inflammatory Cytokines on Sleep .......................................160 8.3.5 Molecular Level Modulation of Cytokines on Sleep ...................160 8.4 Conclusion .................................................................................................161 9. Selective REM Sleep Deprivation and Its Impact on the Immune Response .............................................................................................................167 Javier Velasquez Moctezuma, José Ángel Rojas Zamorano, Enrique Esqueda León, Andrés Quintanar Stephane andAnabel Jiménez Anguiano 9.1 Introduction ................................................................................................167 9.2 Human Studies ............................................................................................168 9.3 Animal Studies ...........................................................................................169 Part III Clinical Research ......................................................................................175 10. Sleep and Immune Correlates: Translational Research in Clinical Populations .........................................................................................................177 Sarosh J. Motivala and Michael Irwin 10.1 The Rationale for Studying Sleep and Immunity in Clinical Populations .................................................................................................177 10.2 Sleep and Immunity in Primary Insomnia ..................................................178 10.2.1 Effects of Experimental Sleep Loss ..............................................178 10.2.2 Primary Insomnia ..........................................................................179 10.2.3 Insomnia in Aging: Influence on Immunity ..................................180 10.2.4 Cytokines: Role in the Regulation of Sleep ..................................181 10.3 Sleep and Immunity in Depression and Substance Dependence ...............182 10.3.1 Depression and Immunity .............................................................183 10.3.2 Alcohol Dependence, Sleep, and Immunity ..................................184 10.4 Sleep and Cytokines in Rheumatoid Arthritis ...........................................187 10.5 Future Directions ........................................................................................189 11. The Stress of Inadequate Sleep and Immune Consequences ........................195 Beatriz Duarte Palma, Sergio Tufìk and Deborah Suchecki 11.1 Introduction ................................................................................................195 11.2 Inadequate Sleep and Disease ...................................................................197 11.3 Immune Function in Sleep Disorders .........................................................198 11.4 Hospitalized Patients ..................................................................................199 11.5 Chronic Inflammatory Diseases and Sleep ................................................200 1.6 Concluding remarks ...................................................................................202 Contents ix 12. Neuroimmunology of Pregnancy-Related Sleep Disturbances .....................207 Michele L. Okiin and Mary E. Coussons-Read 12.1 Introduction ................................................................................................207 12.2 Pregnancy and Alterations in Sleep ...........................................................207 12.2.1 Generalized Sleep Patterns across Pregnancy ...............................207 12.2.2 Sleep Measured by In-lab Polysomnography ...............................208 12.2.3 Sleep Measured by Ambulatory PSG ...........................................209 12.2.4 Sleep Measured by Subjective Reports ........................................210 J2.3 Understanding Sleep in Pregnancy via Animal Models ............................212 12.4 Factors That May Contribute to Disrupted Sleep During Pregnancy ........212 12.4.1 Psychosocial Factors .....................................................................212 12.4.2 Immunological Factors — Cytokines ............................................214 12.4.3 Endocrinological Factors — Hormones .........................................215 12.5 Where Does Sleep Fit In? The Cytokine and Hormone Changes Associated with Sleep Deprivation/Sleep Disorders ..................................216 12.6 Pregnancy Complications ..........................................................................218 12.7 Summary .....................................................................................................220 13. Changes in Sleep and Behavior Following Experimental Immune Stimulation Using Bacterial Endotoxin in Humans .......................................227 Andreas Schuld, Monika Haack, Janet Mullington, and Thomas Pollmächer 13.1 Introduction ................................................................................................227 13.2 The Role of the Neuroendocrine-Immune-CNS Interplay in Clinical Medicine ......................................................................................228 13.3 Changes in Sleep-Wake Behavior Following Endotoxin ...........................229 13.4 Changes in Memory, Mood, and Food Intake Following Endotoxin ........230 14. Inflammation and Sleep ....................................................................................233 Rita A. Trammell, Krishna Jhaveri, and Linda A. Toth 14.1 Inflammation ..............................................................................................233 14.2 Cytokines and Sleep ...................................................................................234 14.3 Acute Inflammation and Sleep ...................................................................234 14.4 Chronic Inflammation and Sleep ................................................................236 14.4.1 Chronic infections .........................................................................236 14.4.2 Chronic Fatigue Syndrome ...........................................................237 14.4.3 Obesity and Type-2 Diabetes ........................................................238 14.4.4 Cancer ............................................................................................239 14.4.5 Age-Related Inflammation ............................................................240 14.5 Genetic Variation in Sleep and Inflammation ............................................240 14.5.1 Genetic Variation in the Inflammatory Response .........................240 14.5.2 Genetic Variation in Sleep Under Normal Conditions and during Inflammatory Disease ........................................................241 14.5.3 The Intersection of Genetic Variation in Sleep and Inflammation .................................................................................243 14.6 Summary and Conclusions .........................................................................245 χ Contents 15. Neuroimmune Activation in Sleep Apnea ......................................................257 Paul J. Mills, Michael G. Ziegler, and Joel E. Dimsdale 15.1 Introduction ................................................................................................257 15.2 Adrenergic Agonists and Receptors ..........................................................257 15.3 Norepinephrine Release and Clearance .....................................................261 15.4 Cytokines in OSA ......................................................................................263 15.4.1 Cytokines and Normal Sleep .........................................................263 15.4.2 Cytokines and OSA ......................................................................263 15.4.3 What Features of OSA Might Lead to Elevations of Inflammatory Cytokines ? ..............................................................264 15.4.4 Cytokines in the Context of Mood and Quality Of Life in OSA ...............................................................................................265 15.5 Nasal Continuous Positive Airway Pressure .............................................266 15.5.1 CPAP Effects on NE levels and Adrenergic Receptors ................267 15.5.2 CPAP Effects on NE Kinetics ......................................................269 15.5.3 CPAP Effects on Inflammation ....................................................271 15.6 Summary ....................................................................................................271 16. Role and Circadian Rhythms of Proinflammatory Cytokines, Cortisol, and Melatonin in Children with Obstructive Sleep Apnea Syndrome ..........................................................................................................275 Luana Nasetti and Luigi Nespoli 16.1 Obstructive Sleep Apnea Syndrome in Children: Clinical Features ..........275 16.2 Pathophysiology of OSAS ..........................................................................276 16.3 OSAS Neuroimmunology ..........................................................................277 16.4 Melatonin Role and Circadian Rhythms in Children with OSAS ..............278 16.5 Cortisol Role and Circadian Rhythms in OSAS ........................................280 16.6 Proinflammatory Cytokines Role and Circadian Rhythms in OSAS .........281 16.6.1 TNF, IL-lß....................................................................................281 16.6.2 Other Cytokines .............................................................................281 16.6.3 Proinflammatory Cytokines Circadian Rhythms in OSAS ...........282 17. Neuroendocrine-Immune Correlates of Sleep and Traumatic Brain Injury (TBI) ......................................................................................................285 Paolo Praia and Anna N. Taylor 17.1 Introduction ................................................................................................285 17.2 TBI and the Neuroendocrine System .........................................................285 17.3 TBI and Immune Surveillance ...................................................................288 17.4 TBI and Sleep .............................................................................................288 17.5 Conclusions ................................................................................................291 18. Neuroimmune Correlates of Sleep in Depression: Role of Cytokines .........295 J. Szelényi and E.S. Vizi 18.1 Introduction ................................................................................................295 18.2 Cytokines and the CNS ..............................................................................295 18.2.1 Cross Talk Between the Innate Immune Response and Sleep .......................................................................................295 Contents xi 18.3 Administering Different Types and Dosages of Cytokines and Their Effects on Sleep ................................................................................298 18.4 Effect of Deprivation of Cytokines on the Duration and Pattern of Sleep ...........................................................................................................299 18.5 Studying the Effects of Sleep Deprivation/Disruption on Cytokine Production ...................................................................................................300 18.6 Regulation of Cytokine Balance by Monoamines in Healthy and in Depressed States .........................................................................................301 18.7 Sleep Disturbances in Diseased States Associated with Altered Cytokine Profile ..........................................................................................304 18.7.1 Infection .........................................................................................304 18.7.2 Depression .....................................................................................305 18.8 Cytokine Balance and Antidepressants ......................................................308 18.8.1 Effect of Multitarget Drugs (e.g. Monoamine Transporter Blockers)........................................................................................308 18.9 Conclusions ................................................................................................311 19. Sleep and Neuroimmune Function in Chronic Fatigue Syndrome .............321 Fumiharu Togo, Benjamin H. Natelson, and Neil Cherniack 19.1 Introduction ................................................................................................321 19.2 Neurological and Neuropsychological Dysfunction in CFS .....................322 19.3 Sleep Studies in CFS ..................................................................................323 19.4 The Neural Immune System in CFS ...........................................................327 20. Narcolepsy with Cataplexy. Hypocretin and Immunological Aspects .........337 Yves Dauvilliers 20.1 Epidemiology and Clinical Features ...........................................................337 20.1.1 Excessive Daytime Sleepiness ......................................................338 20.1.2 Cataplexy ......................................................................................338 20.1.3 Associated Features .......................................................................338 20.1.4 Diagnostic Criteria ........................................................................339 20.2 Pathophysiology ........................................................................................339 20.2.1 Hypocretin (Orexin) System .........................................................339 20.2.2 Genetic and Environmental Factors in Human Narcolepsy .........343 20.2.3 Autoimmunity Hypothesis in Human Narcolepsy .......................345 20.3 Treatment ...................................................................................................347 20.4 Conclusion ..................................................................................................349 Index .........................................................................................................................353
adam_txt	Contents Preface .xiii Acknowledgments .xv Contributors .xvii Part I General Concepts .1 1. Bidirectional Communication Between the Brain and the Immune System .3 Douglas A. Weigent and J. Edwin Blalock 1.1 Introduction .3 1.2 Nervous System Communication to the Immune System .6 1.3 Neuroendocrine Hormone Influence on the Immune System .8 1.4 Actions of Hypothalamic Releasing Hormones .10 1.5 Immune System Communication with the Nervous System Hormones .11 1.6 Cytokine Influences on the Nervous System .12 1.7 Neuroendocrine Hormone Release by Cells of the Immune System .14 1.8 Neurotransmitter Release by Cells of the Immune System .16 1.9 Bidirectional Communication and Sleep .17 1.10 Summary and Conclusions .17 2. Neuroimmunological Correlates of Circadian Rhythmicity in Oral Biology and Medicine .27 Francesco Chiappelli, Olivia S. Cajulis, Audrey Navarro and David R. Moradi 2.1 Introduction .27 vi Contents 2.2 Allostatic Response and Allostatic Intervention: Relevance to Oral Biology and Medicine .29 2.2.1 Allostasis .29 2.2.2 Allostatic Load .30 2.2.3 Allostatic Testing and Intervention .32 2.2.4 Allostasis Is Not Chaos - or Is It? .34 2.3 Mucositis: A Case of Allostatic Load .36 2.3.1 Oral Mucositis .36 2.3.2 Neuroendocrine-Immune Orderly Chaos in OM .39 2.3.3 Circadian Neurobiology and Neuroimmunopathology in OM .46 2.4 Directions for the Future .49 3. Circadian Organization of the Immune Response: Lessons from the Adjuvant Arthritis Model .59 Daniel P. Cardinali, Ana I. Esquifino, Georges J. M. Maestroni and Seithikurippu R. Pandi-Perumal 3.1 The Circadian Clock is One of the most Indispensable Biological Functions .59 3.2 The Immune System Shows Circadian Organization .61 3.3 "Sickness Behavior" Includes Changes in Circadian Rhythms .64 3.4 The Rat Adjuvant Arthritis is an Experimental Model of Rheumatoid Arthritis .66 3.5 Adjuvant Arthritis Disrupts Normal Chronobiological Organization .68 3.6 Melatonin as a Circadian Immunoregulatory Signal in Adjuvant Arthritis .72 Part II Basic Research .85 4. The Biological Clock in Inflammation and Sleep Switch Alterations .87 Marina Bentivoglio, Mikael Nygård, Maria Palomba and Krister Kristensson 4.1 Introduction .87 4.2 Interactions Between the Biological Clock and the Sleep Switch .87 4.3 Effects of Inflammatory Molecules on the SCN and Sleep Switch Structures .90 4.4 Intracellular Inflammatory Regulators .92 4.4.1 SHP. PIAS, and SOCS .92 4.4.2 Intracellular Regulation of Inflammation and the Biological Clock .92 4.5 Concluding Remarks .94 5. Vasoaetive Intestinal Polypeptide and Prolactin Cytokines: Role in Sleep and Some Immune Aspects .97 Fabio Garcia-Garcia, Tatiana Olivares-Bamielos and René Drucker- Colin Contents vii 5.1 Introduction .97 5.2 Vasoactive Intestinal Polypeptide (VIP) . 98 5.2.1 Receptors .98 5.2.2 Gene Regulation .98 5.3 VIP: Brain Distribution .99 5.4 VIP and Sleep Regulation .99 5.5 How VIP Induces REMS: a Hypothesis .102 5.6 VIP Clinical Implications .102 5.7 Prolactin (PRL) .103 5.8 PRL Molecular Aspects .103 5.8.1 Gene Regulation .104 5.8.2 Posttranslational Modifications .104 5.9 PRL and Sleep Regulation .105 5.10 Relationship Between PRL and Stress .107 5.11 Stress and REMS: Role of PRL .108 5.12 PRL Expression and REMS .109 5.13 PRL Clinical Implications .109 6. Immune Signaling to Brain: Mechanisms and Potential Pathways Influencing Sleep .119 Lisa Goehler and Ronald Gaykema 6.1 Introduction .119 6.2 Mechanisms of Immune Signaling to the Brain .119 6.2.1 Neural Pathways .119 6.2.2 Endocrine-Like Pathways: Immune Sensing within the Brain .122 6.3 Neurocircuitry Mediating Sleep and Waking States .124 6.4 What are the Links Between Immune-Brain Interfaces and Sleep Neurocircuitry? .124 6.4.1 Primary Sensory Relay Nuclei .126 6.4.2 Ascending Pathways Influencing Arousal .127 6.5 Conclusions and Perspectives .127 7. Aging, Sleep, and Immunity .133 Laura-Yvette Gorczynski, Ender Terzioglu, Thierry Waelli and R.M. Gorczynski 7.1 Introduction .133 7.2 Altered Sleep and Concomitant Alterations in Immune Function .133 7.3 Cytokines and Sleep .135 7.4 Relationship of Infection to Altered Sleep Behavior .138 7.5 Stress. Hormonal Change, Cytokines. and Sleep Behavior .140 7.6 Age-Related Changes in Sleep and Relation to Altered Immunity .143 7.7 Summary and Conclusions .148 8. Cytokines and Sleep: Neuro-immune Interactions and Regulations .155 Tetsuya Kushikata, Hiwshi Yoshidu and Tadanobu Yasuda 8.1 introduction .155 8.2 Effect of Sleep on Immune System .155 viii Contents 8.2.1 Sleep Pattern and Immune Function .155 8.2.2 Sleep Deprivation and Immune System .156 8.3 Effect of Modulation of Immune System on Sleep .156 8.3.1 Overview .156 8.3.2 Microbial Products, Cytokines, Sleep .157 8.3.3 Proinflammatory Cytokines on Sleep .157 8.3.4 Anti-Inflammatory Cytokines on Sleep .160 8.3.5 Molecular Level Modulation of Cytokines on Sleep .160 8.4 Conclusion .161 9. Selective REM Sleep Deprivation and Its Impact on the Immune Response .167 Javier Velasquez Moctezuma, José Ángel Rojas Zamorano, Enrique Esqueda León, Andrés Quintanar Stephane andAnabel Jiménez Anguiano 9.1 Introduction .167 9.2 Human Studies .168 9.3 Animal Studies .169 Part III Clinical Research .175 10. Sleep and Immune Correlates: Translational Research in Clinical Populations .177 Sarosh J. Motivala and Michael Irwin 10.1 The Rationale for Studying Sleep and Immunity in Clinical Populations .177 10.2 Sleep and Immunity in Primary Insomnia .178 10.2.1 Effects of Experimental Sleep Loss .178 10.2.2 Primary Insomnia .179 10.2.3 Insomnia in Aging: Influence on Immunity .180 10.2.4 Cytokines: Role in the Regulation of Sleep .181 10.3 Sleep and Immunity in Depression and Substance Dependence .182 10.3.1 Depression and Immunity .183 10.3.2 Alcohol Dependence, Sleep, and Immunity .184 10.4 Sleep and Cytokines in Rheumatoid Arthritis .187 10.5 Future Directions .189 11. The Stress of Inadequate Sleep and Immune Consequences .195 Beatriz Duarte Palma, Sergio Tufìk and Deborah Suchecki 11.1 Introduction .195 11.2 Inadequate Sleep and Disease .197 11.3 Immune Function in Sleep Disorders .198 11.4 Hospitalized Patients .199 11.5 Chronic Inflammatory Diseases and Sleep .200 \ 1.6 Concluding remarks .202 Contents ix 12. Neuroimmunology of Pregnancy-Related Sleep Disturbances .207 Michele L. Okiin and Mary E. Coussons-Read 12.1 Introduction .207 12.2 Pregnancy and Alterations in Sleep .207 12.2.1 Generalized Sleep Patterns across Pregnancy .207 12.2.2 Sleep Measured by In-lab Polysomnography .208 12.2.3 Sleep Measured by Ambulatory PSG .209 12.2.4 Sleep Measured by Subjective Reports .210 J2.3 Understanding Sleep in Pregnancy via Animal Models .212 12.4 Factors That May Contribute to Disrupted Sleep During Pregnancy .212 12.4.1 Psychosocial Factors .212 12.4.2 Immunological Factors — Cytokines .214 12.4.3 Endocrinological Factors — Hormones .215 12.5 Where Does Sleep Fit In? The Cytokine and Hormone Changes Associated with Sleep Deprivation/Sleep Disorders .216 12.6 Pregnancy Complications .218 12.7 Summary .220 13. Changes in Sleep and Behavior Following Experimental Immune Stimulation Using Bacterial Endotoxin in Humans .227 Andreas Schuld, Monika Haack, Janet Mullington, and Thomas Pollmächer 13.1 Introduction .227 13.2 The Role of the Neuroendocrine-Immune-CNS Interplay in Clinical Medicine .228 13.3 Changes in Sleep-Wake Behavior Following Endotoxin .229 13.4 Changes in Memory, Mood, and Food Intake Following Endotoxin .230 14. Inflammation and Sleep .233 Rita A. Trammell, Krishna Jhaveri, and Linda A. Toth 14.1 Inflammation .233 14.2 Cytokines and Sleep .234 14.3 Acute Inflammation and Sleep .234 14.4 Chronic Inflammation and Sleep .236 14.4.1 Chronic infections .236 14.4.2 Chronic Fatigue Syndrome .237 14.4.3 Obesity and Type-2 Diabetes .238 14.4.4 Cancer .239 14.4.5 Age-Related Inflammation .240 14.5 Genetic Variation in Sleep and Inflammation .240 14.5.1 Genetic Variation in the Inflammatory Response .240 14.5.2 Genetic Variation in Sleep Under Normal Conditions and during Inflammatory Disease .241 14.5.3 The Intersection of Genetic Variation in Sleep and Inflammation .243 14.6 Summary and Conclusions .245 χ Contents 15. Neuroimmune Activation in Sleep Apnea .257 Paul J. Mills, Michael G. Ziegler, and Joel E. Dimsdale 15.1 Introduction .257 15.2 Adrenergic Agonists and Receptors .257 15.3 Norepinephrine Release and Clearance .261 15.4 Cytokines in OSA .263 15.4.1 Cytokines and Normal Sleep .263 15.4.2 Cytokines and OSA .263 15.4.3 What Features of OSA Might Lead to Elevations of Inflammatory Cytokines'? .264 15.4.4 Cytokines in the Context of Mood and Quality Of Life in OSA .265 15.5 Nasal Continuous Positive Airway Pressure .266 15.5.1 CPAP Effects on NE levels and Adrenergic Receptors .267 15.5.2 CPAP Effects on NE Kinetics .269 15.5.3 CPAP Effects on Inflammation .271 15.6 Summary .271 16. Role and Circadian Rhythms of Proinflammatory Cytokines, Cortisol, and Melatonin in Children with Obstructive Sleep Apnea Syndrome .275 Luana Nasetti and Luigi Nespoli 16.1 Obstructive Sleep Apnea Syndrome in Children: Clinical Features .275 16.2 Pathophysiology of OSAS .276 16.3 OSAS Neuroimmunology .277 16.4 Melatonin Role and Circadian Rhythms in Children with OSAS .278 16.5 Cortisol Role and Circadian Rhythms in OSAS .280 16.6 Proinflammatory Cytokines Role and Circadian Rhythms in OSAS .281 16.6.1 TNF, IL-lß.281 16.6.2 Other Cytokines .281 16.6.3 Proinflammatory Cytokines Circadian Rhythms in OSAS .282 17. Neuroendocrine-Immune Correlates of Sleep and Traumatic Brain Injury (TBI) .285 Paolo Praia and Anna N. Taylor 17.1 Introduction .285 17.2 TBI and the Neuroendocrine System .285 17.3 TBI and Immune Surveillance .288 17.4 TBI and Sleep .288 17.5 Conclusions .291 18. Neuroimmune Correlates of Sleep in Depression: Role of Cytokines .295 J. Szelényi and E.S. Vizi 18.1 Introduction .295 18.2 Cytokines and the CNS .295 18.2.1 Cross Talk Between the Innate Immune Response and Sleep .295 Contents xi 18.3 Administering Different Types and Dosages of Cytokines and Their Effects on Sleep .298 18.4 Effect of Deprivation of Cytokines on the Duration and Pattern of Sleep .299 18.5 Studying the Effects of Sleep Deprivation/Disruption on Cytokine Production .300 18.6 Regulation of Cytokine Balance by Monoamines in Healthy and in Depressed States .301 18.7 Sleep Disturbances in Diseased States Associated with Altered Cytokine Profile .304 18.7.1 Infection .304 18.7.2 Depression .305 18.8 Cytokine Balance and Antidepressants .308 18.8.1 Effect of Multitarget Drugs (e.g. Monoamine Transporter Blockers).308 18.9 Conclusions .311 19. Sleep and Neuroimmune Function in Chronic Fatigue Syndrome .321 Fumiharu Togo, Benjamin H. Natelson, and Neil Cherniack 19.1 Introduction .321 19.2 Neurological and Neuropsychological Dysfunction in CFS .322 19.3 Sleep Studies in CFS .323 19.4 The Neural Immune System in CFS .327 20. Narcolepsy with Cataplexy. Hypocretin and Immunological Aspects .337 Yves Dauvilliers 20.1 Epidemiology and Clinical Features .337 20.1.1 Excessive Daytime Sleepiness .338 20.1.2 Cataplexy .338 20.1.3 Associated Features .338 20.1.4 Diagnostic Criteria .339 20.2 Pathophysiology .339 20.2.1 Hypocretin (Orexin) System .339 20.2.2 Genetic and Environmental Factors in Human Narcolepsy .343 20.2.3 Autoimmunity Hypothesis in Human Narcolepsy .345 20.3 Treatment .347 20.4 Conclusion .349 Index .353
any_adam_object	1
any_adam_object_boolean	1
author_GND	(DE-588)131380419
building	Verbundindex
bvnumber	BV023335277
classification_rvk	WX 3350 YH 4222
ctrlnum	(OCoLC)633646828 (DE-599)BVBBV023335277
discipline	Biologie Medizin
discipline_str_mv	Biologie Medizin
format	Book
fullrecord	<?xml version="1.0" encoding="UTF-8"?><collection xmlns="http://www.loc.gov/MARC21/slim"><record><leader>01838nam a2200457 c 4500</leader><controlfield tag="001">BV023335277</controlfield><controlfield tag="003">DE-604</controlfield><controlfield tag="005">20170912 </controlfield><controlfield tag="007">t</controlfield><controlfield tag="008">080609s2007 gw ad\|\| \|\|\|\| 00\|\|\| eng d</controlfield><datafield tag="015" ind1=" " ind2=" "><subfield code="a">07,N02,0786</subfield><subfield code="2">dnb</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">0387691448</subfield><subfield code="c">Gb. (Pr. in Vorb.)</subfield><subfield code="9">0-387-69144-8</subfield></datafield><datafield tag="020" ind1=" " ind2=" "><subfield code="a">9780387691442</subfield><subfield code="c">Gb. (Pr. in Vorb.)</subfield><subfield code="9">978-0-387-69144-2</subfield></datafield><datafield tag="024" ind1="3" ind2=" "><subfield code="a">9780387691442</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(OCoLC)633646828</subfield></datafield><datafield tag="035" ind1=" " ind2=" "><subfield code="a">(DE-599)BVBBV023335277</subfield></datafield><datafield tag="040" ind1=" " ind2=" "><subfield code="a">DE-604</subfield><subfield code="b">ger</subfield><subfield code="e">rakddb</subfield></datafield><datafield tag="041" ind1="0" ind2=" "><subfield code="a">eng</subfield></datafield><datafield tag="044" ind1=" " ind2=" "><subfield code="a">gw</subfield><subfield code="c">XA-DE-BE</subfield></datafield><datafield tag="049" ind1=" " ind2=" "><subfield code="a">DE-355</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">WX 3350</subfield><subfield code="0">(DE-625)152192:13423</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">YH 4222</subfield><subfield code="0">(DE-625)153542:12928</subfield><subfield code="2">rvk</subfield></datafield><datafield tag="084" ind1=" " ind2=" "><subfield code="a">610</subfield><subfield code="2">sdnb</subfield></datafield><datafield tag="245" ind1="1" ind2="0"><subfield code="a">Neuroimmunology of sleep</subfield><subfield code="c">S. R. Pandi-Perumal ; Daniel P. Cardinali ; George P. Chrousos</subfield></datafield><datafield tag="264" ind1=" " ind2="1"><subfield code="a">Dordrecht</subfield><subfield code="b">Springer</subfield><subfield code="c">2007</subfield></datafield><datafield tag="300" ind1=" " ind2=" "><subfield code="a">XXI, 361 S.</subfield><subfield code="b">Ill., graph. Darst.</subfield></datafield><datafield tag="336" ind1=" " ind2=" "><subfield code="b">txt</subfield><subfield code="2">rdacontent</subfield></datafield><datafield tag="337" ind1=" " ind2=" "><subfield code="b">n</subfield><subfield code="2">rdamedia</subfield></datafield><datafield tag="338" ind1=" " ind2=" "><subfield code="b">nc</subfield><subfield code="2">rdacarrier</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Neuroimmunologie</subfield><subfield code="0">(DE-588)4115376-5</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="650" ind1="0" ind2="7"><subfield code="a">Schlaf</subfield><subfield code="0">(DE-588)4052580-6</subfield><subfield code="2">gnd</subfield><subfield code="9">rswk-swf</subfield></datafield><datafield tag="689" ind1="0" ind2="0"><subfield code="a">Schlaf</subfield><subfield code="0">(DE-588)4052580-6</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2="1"><subfield code="a">Neuroimmunologie</subfield><subfield code="0">(DE-588)4115376-5</subfield><subfield code="D">s</subfield></datafield><datafield tag="689" ind1="0" ind2=" "><subfield code="5">DE-604</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Pandi-Perumal, Seithikurippu R.</subfield><subfield code="d">1964-</subfield><subfield code="e">Sonstige</subfield><subfield code="0">(DE-588)131380419</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Cardinali, Daniel P.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="700" ind1="1" ind2=" "><subfield code="a">Chrousos, George P.</subfield><subfield code="e">Sonstige</subfield><subfield code="4">oth</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Online-Ausgabe</subfield><subfield code="z">0-387-69146-4</subfield></datafield><datafield tag="776" ind1="0" ind2="8"><subfield code="i">Erscheint auch als</subfield><subfield code="n">Online-Ausgabe</subfield><subfield code="z">978-0-387-69146-6</subfield></datafield><datafield tag="856" ind1="4" ind2="2"><subfield code="m">Digitalisierung UB Regensburg</subfield><subfield code="q">application/pdf</subfield><subfield code="u">http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016519154&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA</subfield><subfield code="3">Inhaltsverzeichnis</subfield></datafield><datafield tag="999" ind1=" " ind2=" "><subfield code="a">oai:aleph.bib-bvb.de:BVB01-016519154</subfield></datafield></record></collection>
id	DE-604.BV023335277
illustrated	Illustrated
index_date	2024-07-02T20:59:22Z
indexdate	2024-07-09T21:16:13Z
institution	BVB
isbn	0387691448 9780387691442
language	English
oai_aleph_id	oai:aleph.bib-bvb.de:BVB01-016519154
oclc_num	633646828
open_access_boolean
owner	DE-355 DE-BY-UBR
owner_facet	DE-355 DE-BY-UBR
physical	XXI, 361 S. Ill., graph. Darst.
publishDate	2007
publishDateSearch	2007
publishDateSort	2007
publisher	Springer
record_format	marc
spelling	Neuroimmunology of sleep S. R. Pandi-Perumal ; Daniel P. Cardinali ; George P. Chrousos Dordrecht Springer 2007 XXI, 361 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Neuroimmunologie (DE-588)4115376-5 gnd rswk-swf Schlaf (DE-588)4052580-6 gnd rswk-swf Schlaf (DE-588)4052580-6 s Neuroimmunologie (DE-588)4115376-5 s DE-604 Pandi-Perumal, Seithikurippu R. 1964- Sonstige (DE-588)131380419 oth Cardinali, Daniel P. Sonstige oth Chrousos, George P. Sonstige oth Erscheint auch als Online-Ausgabe 0-387-69146-4 Erscheint auch als Online-Ausgabe 978-0-387-69146-6 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016519154&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis
spellingShingle	Neuroimmunology of sleep Neuroimmunologie (DE-588)4115376-5 gnd Schlaf (DE-588)4052580-6 gnd
subject_GND	(DE-588)4115376-5 (DE-588)4052580-6
title	Neuroimmunology of sleep
title_auth	Neuroimmunology of sleep
title_exact_search	Neuroimmunology of sleep
title_exact_search_txtP	Neuroimmunology of sleep
title_full	Neuroimmunology of sleep S. R. Pandi-Perumal ; Daniel P. Cardinali ; George P. Chrousos
title_fullStr	Neuroimmunology of sleep S. R. Pandi-Perumal ; Daniel P. Cardinali ; George P. Chrousos
title_full_unstemmed	Neuroimmunology of sleep S. R. Pandi-Perumal ; Daniel P. Cardinali ; George P. Chrousos
title_short	Neuroimmunology of sleep
title_sort	neuroimmunology of sleep
topic	Neuroimmunologie (DE-588)4115376-5 gnd Schlaf (DE-588)4052580-6 gnd
topic_facet	Neuroimmunologie Schlaf
url	http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016519154&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA
work_keys_str_mv	AT pandiperumalseithikurippur neuroimmunologyofsleep AT cardinalidanielp neuroimmunologyofsleep AT chrousosgeorgep neuroimmunologyofsleep

Verfügbarkeit

Es ist kein Print-Exemplar vorhanden.

Fernleihe Bestellen Achtung: Nicht im THWS-Bestand! Inhaltsverzeichnis

MARC

Datensatz im Suchindex

Es ist kein Print-Exemplar vorhanden.

Ähnliche Einträge