Biology and mechanics of blood flows: 2 Mechanics and medical aspects
Gespeichert in:
1. Verfasser: | |
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Format: | Buch |
Sprache: | English |
Veröffentlicht: |
New York, NY
Springer
2008
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Schriftenreihe: | CRM series in mathematical physics
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Schlagworte: | |
Online-Zugang: | Inhaltsverzeichnis |
Beschreibung: | XI, 467 S. Ill., graph. Darst. |
ISBN: | 9780387748481 9780387748498 |
Internformat
MARC
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245 | 1 | 0 | |a Biology and mechanics of blood flows |n 2 |p Mechanics and medical aspects |c Marc Thiriet |
264 | 1 | |a New York, NY |b Springer |c 2008 | |
300 | |a XI, 467 S. |b Ill., graph. Darst. | ||
336 | |b txt |2 rdacontent | ||
337 | |b n |2 rdamedia | ||
338 | |b nc |2 rdacarrier | ||
490 | 0 | |a CRM series in mathematical physics | |
650 | 7 | |a Anatomie humaine - Modèles |2 ram | |
650 | 7 | |a Hémodynamique - Modèles mathématiques |2 ram | |
650 | 7 | |a Hémodynamique |2 ram | |
650 | 7 | |a Physiologie cardiovasculaire |2 ram | |
650 | 7 | |a Sang - Circulation |2 ram | |
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Datensatz im Suchindex
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adam_text | Contents
Series Preface V
Introduction 1
1 Anatomy of the Cardiovascular System 9
1.1 Heart 9
1.1.1 Atria 13
1.1.2 Ventricles 14
1.1.3 Aortic Valve 15
1.1.4 Heart Vascularization 17
1.1.5 Heart Innervation 18
1.2 Blood Vessels 20
1.3 Circulatory Networks 26
1.3.1 Aorta 26
1.3.2 Carotid artery 28
1.3.3 Lower Limb Veins 29
1.3.4 Portal System 31
2 Cardiovascular Physiology 35
2.1 Heart 35
2.1.1 Cardiac Cycle 37
2.1.2 Stroke Volume 39
2.1.3 Pressure-Volume Curve 41
2.1.4 Myocardial Oxygen Consumption 43
2.2 Large Blood Vessels 45
2.2.1 Arterial Circulation 46
2.2.2 Venous Return 47
2.2.3 Coronary Circulation 49
2.2.4 Pulmonary Circulation 5.3
2.3 Microcirculation 54
2.3.1 Microvascular Permeability 56
VIII Contents
2.3.2 Exchanges of Water and Hydrophilic Solutes 56
2.3.3 Macioinolecule Permeability 58
2.4 Rhythmicity 59
2.5 Convective Heat Transfer 60
2.6 Regulation of the Circulation 62
2.6.1 Vascular Autoregulation 64
2.6.2 Neural Effects on Heart and Blood Vessels 67
2.6.3 Adrenergic and Cholinergic Receptors 74
2.6.4 Circulation Sensors 77
2.6.5 Short-Term Control of the Circulation 79
2.6.6 Delayed Control of the Circulation 80
3 Images, Signals, and Measurements 87
3.1 Cardiovascular Imaging and Geometry Modeling 87
3.1.1 Imaging Techniques 87
3.1.2 3D Reconstruction 93
3.1.3 Meshing 98
3.2 Hemodynamics Signals 100
3.2.1 Volume and Pressure 100
3.2.2 Flow Rate and Velocity 103
3.3 Measurement of Heart Electric and Magnetic Properties 105
3.3.1 Electrocardiogram 107
3.3.2 Vectorelectrocardiography 110
3.3.3 Magnetocardiography 110
3.3.4 Impedance Plethysmography Ill
3.4 Phantom Experiments 112
3.4.1 Photochromic Tracer Method 112
3.4.2 Laser Doppler Velocimetry 113
3.4.3 Particle Image Velocimetry 113
3.4.4 Electrochemical Sensors 115
3.4.5 Tracking Methods of Wall Deformations 118
4 Rheology 119
4.1 Blood Rheology 119
4.2 Heart Wall 123
4.2.1 Heart Valves 123
4.2.2 Myocardium 124
4.2.3 Small Deformation 124
4.2.4 Large Deformation 125
4.2.5 Poroelasticity 127
4.3 Vessel Wall Rheology 128
4.4 Microrheology 134
Contents IX
5 Hemodynamics 137
5.1 Flow Modeling 137
5.1.1 Physical Quantities 137
5.1.2 Flow Equations 138
5.1.3 Governing Parameters 138
5.1.4 Boundary Conditions 139
5.2 Flow Features 141
5.2.1 Bend Flows 142
5.2.2 Embranchment Flows 146
5.2.3 Wavy Wall 149
5.2.4 Entry Flow 149
5.2.5 Flow Stability 151
5.2.6 Flow Separation 155
5.2.7 Vessel Deformability 156
5.2.8 Wave Propagation 159
5.2.9 Wall Shear Stress 163
5.2.10 Particle Flow 166
5.3 Cardiovascular Flows 168
5.3.1 Cardiac Flow 168
5.3.2 Blood Flow in the Large Blood Vessel 170
5.3.3 Microcirculation 171
6 Numerical Simulations 175
6.1 Heart Pump 175
6.1.1 Electrochemical Firing and Signaling 176
6.1.2 Left Ventricle Behavior 180
6.1.3 Electromechanical Coupling 181
6.2 Blood Flow in Large Vessels 189
6.2.1 Windkessel Model 191
6.2.2 3D Blood Flow 191
6.2.3 Image-Based Detailed Models 193
6.2.4 Space Dimension-Related Multiscale Modeling 193
6.3 Fluid-Structure Interaction 198
6.3.1 Coupling Strategy 199
6.3.2 Wall Models 200
6.3.3 Arbitrary Eulerian-Lagrangian Formulation 200
6.3.4 Immersed Boundary Method 201
6.3.5 Image-Based Fluid-Structure Interaction 203
6.4 Shape Optimization and Parameters Identification 204
6.5 Transmural Transport 205
6.5.1 Literature Data 206
6.5.2 Transport Model 208
6.5.3 Simulation of the Chemical Coupling 210
X Contents
7 Cardiovascular Diseases 213
7.1 Risk Factors 213
7.2 Genetic Background 214
7.3 Oxidative stress 216
7.4 Dysregulation in MicroRNA Activity 217
7.5 Vessel Diseases 217
7.5.1 Aneurism 218
7.5.2 Atheroma 227
7.5.3 Chronic Venous Insufficiency 244
7.6 Heart Diseases 245
7.6.1 Cardiac Deficiency 245
7.6.2 Conduction and Rhythm Disorders 245
7.6.3 Valve Failure 251
7.6.4 Congenital Heart Defects 252
8 Treatments of Cardiovascular Diseases 253
8.1 Medical and Surgical Robotics 254
8.2 Surgery 254
8.2.1 Grafting 255
8.2.2 Aneurism Clipping 258
8.2.3 Ventricular Assist Pumps 258
8.2.4 Valve Prostheses 260
8.2.5 Electrical Stimulation 260
8.3 Endovascular Therapy 261
8.3.1 Radiofrequency Ablation 261
8.3.2 Atherectomy 262
8.3.3 Intravascular Devices 262
8.4 Nanotechnology-Based Therapy 269
8.5 Medical and Surgical Simulators 270
Conclusion 273
A Anatomical, Biological, Medical Glossaries 277
A.I Anatomy Terminology 277
A.2 Biochemistry Terminology 277
A.3 Physiology Pathophysiology Terminology 326
B Adipocyte 343
B.I Adiponectin 344
B.2 Leptin 346
B.3 Resistin 347
B.4 Other Adipokines 348
Contents XI
C Basic Aspects in Mechanics 349
C.I Dimensionless Parameters 349
C.I.I List of Main Dimensionless Flow Parameters 350
C.I.2 Scaling of Time-Dependent Flow in Planar Uniform
Bends 353
C.2 Poiseuille Flow 354
C.3 Womersley Flow 354
C.4 Entry Steady Flow in a Straight Pipe 356
C.5 Rheology Glossary 357
C.6 Phenomenological Models in Rheology 362
C.7 Wave Speed 365
C.8 Static Equilibrium of an Elastic Tube 368
C.9 Tube Deformation 368
C.9.1 Stresses and Strains 368
C.9.2 State Law 368
CIO Collapsible Tubes 370
C.10.1 Tube Law 370
C.I0.2 Normalization and Dimensionless Tube Law 375
C.10.3 One-Dimensional Model of Flow in Collapsible Tubes .. 376
C.10.4 Three-Dimensional Flow in a Collapsed Tube 381
C.ll Dispersion in Fluid Flows 381
C.12 Porous Medium 381
C.13 Turbulence 382
C.14 Pressure Units 382
D Numerical Simulations 385
D.I Numerical Model 386
D.2 Approximation Methods 387
D.3 Basic Techniques in Discretization 388
D.3.1 Finite Difference Method 388
D.3.2 Finite Volume Method 389
D.3.3 Vortex-in-Cell Lagrangian Method 392
D.3.4 Finite Element Method 393
References 397
Notations 451
Index 463
|
adam_txt |
Contents
Series Preface V
Introduction 1
1 Anatomy of the Cardiovascular System 9
1.1 Heart 9
1.1.1 Atria 13
1.1.2 Ventricles 14
1.1.3 Aortic Valve 15
1.1.4 Heart Vascularization 17
1.1.5 Heart Innervation 18
1.2 Blood Vessels 20
1.3 Circulatory Networks 26
1.3.1 Aorta 26
1.3.2 Carotid artery 28
1.3.3 Lower Limb Veins 29
1.3.4 Portal System 31
2 Cardiovascular Physiology 35
2.1 Heart 35
2.1.1 Cardiac Cycle 37
2.1.2 Stroke Volume 39
2.1.3 Pressure-Volume Curve 41
2.1.4 Myocardial Oxygen Consumption 43
2.2 Large Blood Vessels 45
2.2.1 Arterial Circulation 46
2.2.2 Venous Return 47
2.2.3 Coronary Circulation 49
2.2.4 Pulmonary Circulation 5.3
2.3 Microcirculation 54
2.3.1 Microvascular Permeability 56
VIII Contents
2.3.2 Exchanges of Water and Hydrophilic Solutes 56
2.3.3 Macioinolecule Permeability 58
2.4 Rhythmicity 59
2.5 Convective Heat Transfer 60
2.6 Regulation of the Circulation 62
2.6.1 Vascular Autoregulation 64
2.6.2 Neural Effects on Heart and Blood Vessels 67
2.6.3 Adrenergic and Cholinergic Receptors 74
2.6.4 Circulation Sensors 77
2.6.5 Short-Term Control of the Circulation 79
2.6.6 Delayed Control of the Circulation 80
3 Images, Signals, and Measurements 87
3.1 Cardiovascular Imaging and Geometry Modeling 87
3.1.1 Imaging Techniques 87
3.1.2 3D Reconstruction 93
3.1.3 Meshing 98
3.2 Hemodynamics Signals 100
3.2.1 Volume and Pressure 100
3.2.2 Flow Rate and Velocity 103
3.3 Measurement of Heart Electric and Magnetic Properties 105
3.3.1 Electrocardiogram 107
3.3.2 Vectorelectrocardiography 110
3.3.3 Magnetocardiography 110
3.3.4 Impedance Plethysmography Ill
3.4 Phantom Experiments 112
3.4.1 Photochromic Tracer Method 112
3.4.2 Laser Doppler Velocimetry 113
3.4.3 Particle Image Velocimetry 113
3.4.4 Electrochemical Sensors 115
3.4.5 Tracking Methods of Wall Deformations 118
4 Rheology 119
4.1 Blood Rheology 119
4.2 Heart Wall 123
4.2.1 Heart Valves 123
4.2.2 Myocardium 124
4.2.3 Small Deformation 124
4.2.4 Large Deformation 125
4.2.5 Poroelasticity 127
4.3 Vessel Wall Rheology 128
4.4 Microrheology 134
Contents IX
5 Hemodynamics 137
5.1 Flow Modeling 137
5.1.1 Physical Quantities 137
5.1.2 Flow Equations 138
5.1.3 Governing Parameters 138
5.1.4 Boundary Conditions 139
5.2 Flow Features 141
5.2.1 Bend Flows 142
5.2.2 Embranchment Flows 146
5.2.3 Wavy Wall 149
5.2.4 Entry Flow 149
5.2.5 Flow Stability 151
5.2.6 Flow Separation 155
5.2.7 Vessel Deformability 156
5.2.8 Wave Propagation 159
5.2.9 Wall Shear Stress 163
5.2.10 Particle Flow 166
5.3 Cardiovascular Flows 168
5.3.1 Cardiac Flow 168
5.3.2 Blood Flow in the Large Blood Vessel 170
5.3.3 Microcirculation 171
6 Numerical Simulations 175
6.1 Heart Pump 175
6.1.1 Electrochemical Firing and Signaling 176
6.1.2 Left Ventricle Behavior 180
6.1.3 Electromechanical Coupling 181
6.2 Blood Flow in Large Vessels 189
6.2.1 Windkessel Model 191
6.2.2 3D Blood Flow 191
6.2.3 Image-Based Detailed Models 193
6.2.4 Space Dimension-Related Multiscale Modeling 193
6.3 Fluid-Structure Interaction 198
6.3.1 Coupling Strategy 199
6.3.2 Wall Models 200
6.3.3 Arbitrary Eulerian-Lagrangian Formulation 200
6.3.4 Immersed Boundary Method 201
6.3.5 Image-Based Fluid-Structure Interaction 203
6.4 Shape Optimization and Parameters Identification 204
6.5 Transmural Transport 205
6.5.1 Literature Data 206
6.5.2 Transport Model 208
6.5.3 Simulation of the Chemical Coupling 210
X Contents
7 Cardiovascular Diseases 213
7.1 Risk Factors 213
7.2 Genetic Background 214
7.3 Oxidative stress 216
7.4 Dysregulation in MicroRNA Activity 217
7.5 Vessel Diseases 217
7.5.1 Aneurism 218
7.5.2 Atheroma 227
7.5.3 Chronic Venous Insufficiency 244
7.6 Heart Diseases 245
7.6.1 Cardiac Deficiency 245
7.6.2 Conduction and Rhythm Disorders 245
7.6.3 Valve Failure 251
7.6.4 Congenital Heart Defects 252
8 Treatments of Cardiovascular Diseases 253
8.1 Medical and Surgical Robotics 254
8.2 Surgery 254
8.2.1 Grafting 255
8.2.2 Aneurism Clipping 258
8.2.3 Ventricular Assist Pumps 258
8.2.4 Valve Prostheses 260
8.2.5 Electrical Stimulation 260
8.3 Endovascular Therapy 261
8.3.1 Radiofrequency Ablation 261
8.3.2 Atherectomy 262
8.3.3 Intravascular Devices 262
8.4 Nanotechnology-Based Therapy 269
8.5 Medical and Surgical Simulators 270
Conclusion 273
A Anatomical, Biological, Medical Glossaries 277
A.I Anatomy Terminology 277
A.2 Biochemistry Terminology 277
A.3 Physiology Pathophysiology Terminology 326
B Adipocyte 343
B.I Adiponectin 344
B.2 Leptin 346
B.3 Resistin 347
B.4 Other Adipokines 348
Contents XI
C Basic Aspects in Mechanics 349
C.I Dimensionless Parameters 349
C.I.I List of Main Dimensionless Flow Parameters 350
C.I.2 Scaling of Time-Dependent Flow in Planar Uniform
Bends 353
C.2 Poiseuille Flow 354
C.3 Womersley Flow 354
C.4 Entry Steady Flow in a Straight Pipe 356
C.5 Rheology Glossary 357
C.6 Phenomenological Models in Rheology 362
C.7 Wave Speed 365
C.8 Static Equilibrium of an Elastic Tube 368
C.9 Tube Deformation 368
C.9.1 Stresses and Strains 368
C.9.2 State Law 368
CIO Collapsible Tubes 370
C.10.1 Tube Law 370
C.I0.2 Normalization and Dimensionless Tube Law 375
C.10.3 One-Dimensional Model of Flow in Collapsible Tubes . 376
C.10.4 Three-Dimensional Flow in a Collapsed Tube 381
C.ll Dispersion in Fluid Flows 381
C.12 Porous Medium 381
C.13 Turbulence 382
C.14 Pressure Units 382
D Numerical Simulations 385
D.I Numerical Model 386
D.2 Approximation Methods 387
D.3 Basic Techniques in Discretization 388
D.3.1 Finite Difference Method 388
D.3.2 Finite Volume Method 389
D.3.3 Vortex-in-Cell Lagrangian Method 392
D.3.4 Finite Element Method 393
References 397
Notations 451
Index 463 |
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index_date | 2024-07-02T20:52:47Z |
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isbn | 9780387748481 9780387748498 |
language | English |
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physical | XI, 467 S. Ill., graph. Darst. |
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spelling | Thiriet, Marc Verfasser (DE-588)1019322721 aut Biology and mechanics of blood flows 2 Mechanics and medical aspects Marc Thiriet New York, NY Springer 2008 XI, 467 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier CRM series in mathematical physics Anatomie humaine - Modèles ram Hémodynamique - Modèles mathématiques ram Hémodynamique ram Physiologie cardiovasculaire ram Sang - Circulation ram (DE-604)BV023318125 2 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016502276&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
spellingShingle | Thiriet, Marc Biology and mechanics of blood flows Anatomie humaine - Modèles ram Hémodynamique - Modèles mathématiques ram Hémodynamique ram Physiologie cardiovasculaire ram Sang - Circulation ram |
title | Biology and mechanics of blood flows |
title_auth | Biology and mechanics of blood flows |
title_exact_search | Biology and mechanics of blood flows |
title_exact_search_txtP | Biology and mechanics of blood flows |
title_full | Biology and mechanics of blood flows 2 Mechanics and medical aspects Marc Thiriet |
title_fullStr | Biology and mechanics of blood flows 2 Mechanics and medical aspects Marc Thiriet |
title_full_unstemmed | Biology and mechanics of blood flows 2 Mechanics and medical aspects Marc Thiriet |
title_short | Biology and mechanics of blood flows |
title_sort | biology and mechanics of blood flows mechanics and medical aspects |
topic | Anatomie humaine - Modèles ram Hémodynamique - Modèles mathématiques ram Hémodynamique ram Physiologie cardiovasculaire ram Sang - Circulation ram |
topic_facet | Anatomie humaine - Modèles Hémodynamique - Modèles mathématiques Hémodynamique Physiologie cardiovasculaire Sang - Circulation |
url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016502276&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
volume_link | (DE-604)BV023318125 |
work_keys_str_mv | AT thirietmarc biologyandmechanicsofbloodflows2 |