Optical clearing of tissues and blood:
This book describes an optical clearing method based on reversible reduction of tissue scattering due to refractive index matching of scatterers and ground matter. This technique, which has been of great interest for research and application in the last decade, is a promising technique for future de...
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| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Bellingham, Wash.
SPIE Press
2006
|
| Subjects: | |
| Online Access: | Table of contents Inhaltsverzeichnis |
| Summary: | This book describes an optical clearing method based on reversible reduction of tissue scattering due to refractive index matching of scatterers and ground matter. This technique, which has been of great interest for research and application in the last decade, is a promising technique for future developments in the fields of tissue imaging, spectroscopy, phototherapy, and laser surgery. |
| Item Description: | Includes bibliographical references (p. [217]-244) and index |
| Physical Description: | xii, 254 S. Ill., graph. Darst. 26 cm |
| ISBN: | 0819460060 |
Staff View
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| 500 | |a Includes bibliographical references (p. [217]-244) and index | ||
| 520 | 3 | |a This book describes an optical clearing method based on reversible reduction of tissue scattering due to refractive index matching of scatterers and ground matter. This technique, which has been of great interest for research and application in the last decade, is a promising technique for future developments in the fields of tissue imaging, spectroscopy, phototherapy, and laser surgery. | |
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Record in the Search Index
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| adam_text | Contents
Preface vii
Introduction: Brief Review ix
Chapter 1 Tissue and Blood Optical Immersion by Exogenous
Chemical Agents 1
1.1 Tissue Structure and Scattering Properties 1
1.2 Principles of Optical Immersion and Chemical Agent Diffusion 12
1.3 Thermodynamics of Water Transport Through a Semipermeable
Membrane 18
1.4 Tissue Swelling and Hydration 19
Chapter 2 Optical Clearing of Fibrous Tissues 23
2.1 Spectral Properties of Immersed Eye Sclera 23
2.1.1 Monte Carlo modeling 23
2.1.2 In vitro measurements 32
2.2 In vitro Frequency-Domain Measurements of Eye Sclera 52
2.3 In vivo Measurements of Eye Sclera 54
2.4 Dura Mater Immersion and Agent Diffusion Rate 58
2.5 Conclusions 60
Chapter 3 Optical Clearing of Skin 61
3.1 Introduction 61
3.2 In vitro Speckle and Spectral Measurements 63
3.3 In vivo Spectral Reflectance Measurements 70
3.4 In vivo Frequency-Domain Measurements 75
3.5 OCT Imaging 78
Chapter 4 Optical Clearing of Gastric Tissue 83
4.1 Spectral Measurements 83
4.2 OCT Imaging 84
Chapter 5 Tissue Structural Properties Studies at Optical Immersion 87
5.1 Polarization Measurements 87
5.2 Confocal Microscopy 94
5.3 Fluorescence Measurements 95
5.3.1 Transmittance of fluorescent radiation 95
5.3.2 In vivo measurements for intact human skin 97
V
vi Optical Clearing of Tissues and Blood
5.3.3 Two-photon scanning fluorescence microscopy 98
5.4 The Second Harmonic Generation 103
Chapter 6 Optical Clearing of Blood, Cells, and Microorganisms 107
6.1 Blood Flow and Microvessel Network Imaging 107
6.2 OCT Measurements of Blood Optical Clearing 112
6.3 Theoretical Analysis of Blood Optical Clearing 125
6.4 Optical Immersion of Cells and Microorganisms 133
Chapter 7 Chemical Agent Delivery 147
7.1 Introduction 147
7.2 Cosmetic Preparations and Skin Permeation 148
7.3 Diffusion of Macromolecules in Tissues 151
7.4 Enhanced Diffusion of Molecules Through Tissues 155
7.4.1 Occlusion 155
7.4.2 Chemical enhancers 156
7.4.3 Physical enhancers 157
7.5 Skin Reservoirs for Topically Applied Clearing Agents 162
Chapter 8 Applications 167
8.1 Glucose Sensing 167
8.1.1 Introduction 167
8.1.2 Tissue and blood scattering spectroscopy 167
8.1.3 OCT measurements 170
8.2 Speckle Technologies 175
8.2.1 Speckle topography and tomography 175
8.2.2 Diffusion-wave spectroscopy and functional imaging 186
8.3 Precision Tissue Photodisruption and Tattoo Removal 188
Chapter 9 Other Methods of Tissue Optical Properties Control 193
9.1 Tissue Compression and Stretching 193
9.2 Temperature Effects and Tissue Coagulation 205
9.3 Tissue Whitening 211
Conclusion 213
References 217
Index 245
|
| adam_txt |
Contents
Preface vii
Introduction: Brief Review ix
Chapter 1 Tissue and Blood Optical Immersion by Exogenous
Chemical Agents 1
1.1 Tissue Structure and Scattering Properties 1
1.2 Principles of Optical Immersion and Chemical Agent Diffusion 12
1.3 Thermodynamics of Water Transport Through a Semipermeable
Membrane 18
1.4 Tissue Swelling and Hydration 19
Chapter 2 Optical Clearing of Fibrous Tissues 23
2.1 Spectral Properties of Immersed Eye Sclera 23
2.1.1 Monte Carlo modeling 23
2.1.2 In vitro measurements 32
2.2 In vitro Frequency-Domain Measurements of Eye Sclera 52
2.3 In vivo Measurements of Eye Sclera 54
2.4 Dura Mater Immersion and Agent Diffusion Rate 58
2.5 Conclusions 60
Chapter 3 Optical Clearing of Skin 61
3.1 Introduction 61
3.2 In vitro Speckle and Spectral Measurements 63
3.3 In vivo Spectral Reflectance Measurements 70
3.4 In vivo Frequency-Domain Measurements 75
3.5 OCT Imaging 78
Chapter 4 Optical Clearing of Gastric Tissue 83
4.1 Spectral Measurements 83
4.2 OCT Imaging 84
Chapter 5 Tissue Structural Properties Studies at Optical Immersion 87
5.1 Polarization Measurements 87
5.2 Confocal Microscopy 94
5.3 Fluorescence Measurements 95
5.3.1 Transmittance of fluorescent radiation 95
5.3.2 In vivo measurements for intact human skin 97
V
vi Optical Clearing of Tissues and Blood
5.3.3 Two-photon scanning fluorescence microscopy 98
5.4 The Second Harmonic Generation 103
Chapter 6 Optical Clearing of Blood, Cells, and Microorganisms 107
6.1 Blood Flow and Microvessel Network Imaging 107
6.2 OCT Measurements of Blood Optical Clearing 112
6.3 Theoretical Analysis of Blood Optical Clearing 125
6.4 Optical Immersion of Cells and Microorganisms 133
Chapter 7 Chemical Agent Delivery 147
7.1 Introduction 147
7.2 Cosmetic Preparations and Skin Permeation 148
7.3 Diffusion of Macromolecules in Tissues 151
7.4 Enhanced Diffusion of Molecules Through Tissues 155
7.4.1 Occlusion 155
7.4.2 Chemical enhancers 156
7.4.3 Physical enhancers 157
7.5 Skin Reservoirs for Topically Applied Clearing Agents 162
Chapter 8 Applications 167
8.1 Glucose Sensing 167
8.1.1 Introduction 167
8.1.2 Tissue and blood scattering spectroscopy 167
8.1.3 OCT measurements 170
8.2 Speckle Technologies 175
8.2.1 Speckle topography and tomography 175
8.2.2 Diffusion-wave spectroscopy and functional imaging 186
8.3 Precision Tissue Photodisruption and Tattoo Removal 188
Chapter 9 Other Methods of Tissue Optical Properties Control 193
9.1 Tissue Compression and Stretching 193
9.2 Temperature Effects and Tissue Coagulation 205
9.3 Tissue Whitening 211
Conclusion 213
References 217
Index 245 |
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| spelling | Tučin, Valerij V. 1944- Verfasser (DE-588)132097613 aut Optical clearing of tissues and blood Valery V. Tuchin Bellingham, Wash. SPIE Press 2006 xii, 254 S. Ill., graph. Darst. 26 cm txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references (p. [217]-244) and index This book describes an optical clearing method based on reversible reduction of tissue scattering due to refractive index matching of scatterers and ground matter. This technique, which has been of great interest for research and application in the last decade, is a promising technique for future developments in the fields of tissue imaging, spectroscopy, phototherapy, and laser surgery. Tissues Imaging Tissues Optical properties Imaging systems in medicine Medical physics Gewebe (DE-588)4020840-0 gnd rswk-swf Optische Eigenschaft (DE-588)4123887-4 gnd rswk-swf Blut (DE-588)4007259-9 gnd rswk-swf Gewebe (DE-588)4020840-0 s Blut (DE-588)4007259-9 s Optische Eigenschaft (DE-588)4123887-4 s DE-604 http://www.loc.gov/catdir/toc/ecip0516/2005022126.html Table of contents HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016458727&sequence=000006&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Tučin, Valerij V. 1944- Optical clearing of tissues and blood Tissues Imaging Tissues Optical properties Imaging systems in medicine Medical physics Gewebe (DE-588)4020840-0 gnd Optische Eigenschaft (DE-588)4123887-4 gnd Blut (DE-588)4007259-9 gnd |
| subject_GND | (DE-588)4020840-0 (DE-588)4123887-4 (DE-588)4007259-9 |
| title | Optical clearing of tissues and blood |
| title_auth | Optical clearing of tissues and blood |
| title_exact_search | Optical clearing of tissues and blood |
| title_exact_search_txtP | Optical clearing of tissues and blood |
| title_full | Optical clearing of tissues and blood Valery V. Tuchin |
| title_fullStr | Optical clearing of tissues and blood Valery V. Tuchin |
| title_full_unstemmed | Optical clearing of tissues and blood Valery V. Tuchin |
| title_short | Optical clearing of tissues and blood |
| title_sort | optical clearing of tissues and blood |
| topic | Tissues Imaging Tissues Optical properties Imaging systems in medicine Medical physics Gewebe (DE-588)4020840-0 gnd Optische Eigenschaft (DE-588)4123887-4 gnd Blut (DE-588)4007259-9 gnd |
| topic_facet | Tissues Imaging Tissues Optical properties Imaging systems in medicine Medical physics Gewebe Optische Eigenschaft Blut |
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