Protein crystallography: a concise guide
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Baltimore, Md
Johns Hopkins Univ. Press
2008
|
| Subjects: | |
| Online Access: | Contributor biographical information Publisher description Inhaltsverzeichnis |
| Physical Description: | VIII, 136 S. Ill., graph. Darst. |
| ISBN: | 0801888069 9780801888069 0801888085 9780801888083 |
Staff View
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| 300 | |a VIII, 136 S. |b Ill., graph. Darst. | ||
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| 650 | 4 | |a Protein Conformation | |
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| 650 | 4 | |a Proteomics |x methods | |
| 650 | 4 | |a X-ray crystallography | |
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Record in the Search Index
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| adam_text | Contents
Preface
ix
Chapter I
.
Introduction
1
1.1
What Is X-ray Crystallography?
1
1.2
A Quick Look at Protein Crystals
12
1.3
Noncrystalline Specimens
15
1.4
Summary
17
Further Reading
17
Chapter
2.
A Physical Understanding of Diffraction
19
2.1
What Is
Diffraction?
19
2.2
Diffraction from One-Dimensional Crystals
25
2.3
Reconstructing Images from Diffraction Patterns
29
2.4
Summary
35
Further Reading
36
Chapter
3.
Diffraction from Three-Dimensional Crystals
37
3.1
The Electron Density Function in Three Dimensions
37
3.2
Calculating the Diffraction Pattern from a Known Structure
49
3.3
Summan·
53
Further Reading
54
viii Contents
Chapter
4.
Phase Determination by Isomorphous Replacement
55
4.1
Measuring the Phases
55
4.2
MAD Phasing
61
4.3
Fitting Models to Experimental Electron Density Maps
68
4.4
Summary
70
Further Reading
70
Chapter
5.
The Patterson Function
72
5.1
Definition of the Patterson Function
72
5.2
Using the Patterson Function to Locate Atoms
76
5.3
Summary
81
Further Reading
82
Chapter
6.
Phasing with Partially Known Structures
83
6.1
Difference Fourier Maps
83
6.2
Molecular Replacement
87
6.3
Summary
101
Further Reading
101
Chapter
7.
Crystallographic Refinement
102
7.1
Refinement Improves the Model
102
7.2
Least-Squares Refinement
103
7.3
Summary 111
Further Reading
112
Glossary
113
Index
131
|
| adam_txt |
Contents
Preface
ix
Chapter I
.
Introduction
1
1.1
What Is X-ray Crystallography?
1
1.2
A Quick Look at Protein Crystals
12
1.3
Noncrystalline Specimens
15
1.4
Summary
17
Further Reading
17
Chapter
2.
A Physical Understanding of Diffraction
19
2.1
What Is
Diffraction?
19
2.2
Diffraction from One-Dimensional Crystals
25
2.3
Reconstructing Images from Diffraction Patterns
29
2.4
Summary
35
Further Reading
36
Chapter
3.
Diffraction from Three-Dimensional Crystals
37
3.1
The Electron Density Function in Three Dimensions
37
3.2
Calculating the Diffraction Pattern from a Known Structure
49
3.3
Summan·
53
Further Reading
54
viii Contents
Chapter
4.
Phase Determination by Isomorphous Replacement
55
4.1
Measuring the Phases
55
4.2
MAD Phasing
61
4.3
Fitting Models to Experimental Electron Density Maps
68
4.4
Summary
70
Further Reading
70
Chapter
5.
The Patterson Function
72
5.1
Definition of the Patterson Function
72
5.2
Using the Patterson Function to Locate Atoms
76
5.3
Summary
81
Further Reading
82
Chapter
6.
Phasing with Partially Known Structures
83
6.1
Difference Fourier Maps
83
6.2
Molecular Replacement
87
6.3
Summary
101
Further Reading
101
Chapter
7.
Crystallographic Refinement
102
7.1
Refinement Improves the Model
102
7.2
Least-Squares Refinement
103
7.3
Summary 111
Further Reading
112
Glossary
113
Index
131 |
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| author | Lattman, Eaton Loll, Patrick J. |
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| callnumber-first | Q - Science |
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| callnumber-subject | QP - Physiology |
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| dewey-sort | 3612 41575 |
| dewey-tens | 610 - Medicine and health |
| discipline | Physik Biologie Chemie Medizin |
| discipline_str_mv | Physik Biologie Chemie Medizin |
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| index_date | 2024-07-02T20:21:29Z |
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| institution | BVB |
| isbn | 0801888069 9780801888069 0801888085 9780801888083 |
| language | English |
| lccn | 2007036099 |
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| physical | VIII, 136 S. Ill., graph. Darst. |
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| publisher | Johns Hopkins Univ. Press |
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| spelling | Lattman, Eaton Verfasser aut Protein crystallography a concise guide Eaton E. Lattman and Patrick J. Loll Baltimore, Md Johns Hopkins Univ. Press 2008 VIII, 136 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Cristalografia de raios x larpcal Eiwitten gtt Kristallografie gtt Proteínas (estrutura) larpcal Crystallography, X-Ray methods Protein Conformation Proteins Structure Proteins chemistry Proteomics methods X-ray crystallography Röntgenstrukturanalyse (DE-588)4137203-7 gnd rswk-swf Kristallographie (DE-588)4033217-2 gnd rswk-swf Proteine (DE-588)4076388-2 gnd rswk-swf Proteine (DE-588)4076388-2 s Kristallographie (DE-588)4033217-2 s DE-604 Röntgenstrukturanalyse (DE-588)4137203-7 s b DE-604 Loll, Patrick J. Verfasser aut http://www.loc.gov/catdir/enhancements/fy0805/2007036099-b.html Contributor biographical information http://www.loc.gov/catdir/enhancements/fy0805/2007036099-d.html Publisher description Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016420295&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Lattman, Eaton Loll, Patrick J. Protein crystallography a concise guide Cristalografia de raios x larpcal Eiwitten gtt Kristallografie gtt Proteínas (estrutura) larpcal Crystallography, X-Ray methods Protein Conformation Proteins Structure Proteins chemistry Proteomics methods X-ray crystallography Röntgenstrukturanalyse (DE-588)4137203-7 gnd Kristallographie (DE-588)4033217-2 gnd Proteine (DE-588)4076388-2 gnd |
| subject_GND | (DE-588)4137203-7 (DE-588)4033217-2 (DE-588)4076388-2 |
| title | Protein crystallography a concise guide |
| title_auth | Protein crystallography a concise guide |
| title_exact_search | Protein crystallography a concise guide |
| title_exact_search_txtP | Protein crystallography a concise guide |
| title_full | Protein crystallography a concise guide Eaton E. Lattman and Patrick J. Loll |
| title_fullStr | Protein crystallography a concise guide Eaton E. Lattman and Patrick J. Loll |
| title_full_unstemmed | Protein crystallography a concise guide Eaton E. Lattman and Patrick J. Loll |
| title_short | Protein crystallography |
| title_sort | protein crystallography a concise guide |
| title_sub | a concise guide |
| topic | Cristalografia de raios x larpcal Eiwitten gtt Kristallografie gtt Proteínas (estrutura) larpcal Crystallography, X-Ray methods Protein Conformation Proteins Structure Proteins chemistry Proteomics methods X-ray crystallography Röntgenstrukturanalyse (DE-588)4137203-7 gnd Kristallographie (DE-588)4033217-2 gnd Proteine (DE-588)4076388-2 gnd |
| topic_facet | Cristalografia de raios x Eiwitten Kristallografie Proteínas (estrutura) Crystallography, X-Ray methods Protein Conformation Proteins Structure Proteins chemistry Proteomics methods X-ray crystallography Röntgenstrukturanalyse Kristallographie Proteine |
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