Leading pharmaceutical innovation: trends and drivers for growth in the pharmaceutical industry
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Berlin [u.a.]
Springer
2008
|
| Edition: | 2. ed. |
| Subjects: | |
| Online Access: | Inhaltstext Inhaltsverzeichnis |
| Physical Description: | XV, 186 S. graph. Darst., Kt. |
| ISBN: | 9783540776352 3540776354 |
Staff View
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Record in the Search Index
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| adam_text |
OLIVER GASSMANN * GERRIT REEPMEYER MAXIMILIAN VON ZEDTWITZ LEADING
PHARMACEUTICAL INNOVATION TRENDS AND DRIVERS FOR GROWTH IN THE
PHARMACEUTICAL INDUSTRY SECOND EDITION 4Y SPRINGER CONTENTS I.
INNOVATION: KEY TO SUCCESS IN THE PHARMACEUTICAL INDUSTRY 1 THE
PRODUCTIVITY PARADOX 1 THE BLOCKBUSTER IMPERATIVE 4 HIGH RISKS IN DRUG
DEVELOPMENT 10 STRATEGIES FOR GROWTH 12 DIFFERENTIATION VIA CLINICAL
PROFILES , .; 15 ENTERING THE MARKET QUICKLY 16 CONCLUSIONS 17 II. THE
INDUSTRY CHALLENGE: DO YOU REALLY WANT TO BE IN THIS BUSINESS? 19 HIGH
COMPLEXITY OF THE INDUSTRY 19 HOW ATTRACTIVE IS THE PHARMACEUTICAL
INDUSTRY? 22 FORCE 1: BARGAINING'POWER OF SUPPLIERS 24 FORCE 2:
BARGAINING POWER OF BUYERS 25 FORCE 3: RISK OF ENTRY FROM POTENTIAL
COMPETITORS 26 FORCE 4: THREAT OF SUBSTITUTE PRODUCTS 27 FORCE 5:
RIVALRY AMONG ESTABLISHED COMPANIES 28 FORCE 6: THE REGULATORS :.'.' 28
CONCLUSIONS 30 III. THE SCIENCE AND TECHNOLOGY CHALLENGE: HOW TO FIND
NEW DRUGS 33 RISE OF THE BIOTECHNOLOGY INDUSTRY: BOOSTING INNOVATION 33
HIGH-THROUGHPUT SCREENING: FAIL EARLIER, SUCCEED SOONER 38 COMBINATORIAL
CHEMISTRY: CUT EXPERIMENTAL CYCLE TIMES 39 BIOINFORMATICS: MORE THAN 100
GIGABYTES OF DATA PER DAY 40 PROTEOMICS: PROFITING FROM THE HUMAN GENOME
PROJECT 42 GENOMICS: TOWARDS INDIVIDUALIZATION AND MASS CUSTOMIZATION
.43 PHARMACOGENOMICS: CREATE TAILOR-MADE DRUGS 45 MOLECULAR DESIGN:
FROM EXPERIMENTING TO ANALYTIC DESIGN 47 CONCLUSIONS 48 XIV CONTENTS IV.
THE PIPELINE MANAGEMENT CHALLENGE: HOW TO ORGANIZE INNOVATION 51 THE
RELEVANCE OF PIPELINE MANAGEMENT 51 COMPLEXITY AND PHASES OF THE R&D
PROCESS 56 THE IMPORTANCE OF PROJECT AND PORTFOLIO MANAGEMENT 65 THE
DISAGGREGATION OF THE PHARMACEUTICAL VALUE CHAIN 68 IMPACT OF
OUTSOURCING ON PHARMACEUTICAL R&D 71 RISING IMPORTANCE OF R&D
COLLABORATIONS 75 RESEARCH ALLIANCES: ACCESSING EARLY-STAGE INNOVATION
78 IN-LICENSING:'ENHANCING THE INNOVATION PIPELINE 1 : 81
CO-DEVELOPMENT: MUTUALLY BENEFITING FROM JOINT RESOURCES, 83
OUT-LICENSING: COMMERCIALIZING INTERNAL RESEARCH RESULTS 86 HOW TO
COMMERCIALIZE A BREAKTHROUGH TECHNOLOGY 95 CONCLUSIONS 100 V. THE
INTERNATIONALIZATION CHALLENGE: WHERE TO GET ACCESS TO INNOVATION 103
TRENDS AND DRIVERS OF R&D INTERNATIONALIZATION 103 PRIMARY LOCATIONS OF
PHARMACEUTICAL R&D AROUND THE WORLD 108 NEW OPPORTUNITIES FOR DRUG
DEVELOPMENT IN CHINA.,- 111 THREE PRINCIPAL PROBLEMS OF DISPERSED R&D
117 CONCLUSIONS 121 VI. MANAGEMENT ANSWERS TO PHARMACEUTICAL R&D
CHALLENGES .123 MANAGING R&D ORGANIZATION AT ROCHE 123 MANAGING R&D
STRATEGY AT SCHERING 125 MANAGING THE RESEARCH-TO-DEVELOPMENT HANDOVER
AT ROCHE 127 MANAGING OUTSOURCING ACTIVITIES AT SOLVIAS. 130 MANAGING
INTELLECTUAL PROPERTY RIGHTS AT BAYER 133 MANAGING OUT-LICENSING
ATNOVARTIS 137 MANAGING UNCERTAINTY AT ROCHE 144 MANAGING GLOBAL R&D AT
MAJOR SWISS PHARMA COMPANIES 145 MANAGING A NICHE-MARKET STRATEGY AT
INTARCIA 151 MANAGING VIRTUAL PROJECT MANAGEMENT POOLS AT ROCHE 153
CONCLUSIONS , ., .156 VII. FUTURE DIRECTIONS AND TRENDS . *. 159
CONTENTS XV BIBLIOGRAPHY 165 INDEX 173 GLOSSARY '. 179 AUTHORS 185 |
| adam_txt |
OLIVER GASSMANN * GERRIT REEPMEYER MAXIMILIAN VON ZEDTWITZ LEADING
PHARMACEUTICAL INNOVATION TRENDS AND DRIVERS FOR GROWTH IN THE
PHARMACEUTICAL INDUSTRY SECOND EDITION 4Y SPRINGER CONTENTS I.
INNOVATION: KEY TO SUCCESS IN THE PHARMACEUTICAL INDUSTRY 1 THE
PRODUCTIVITY PARADOX 1 THE BLOCKBUSTER IMPERATIVE 4 HIGH RISKS IN DRUG
DEVELOPMENT 10 STRATEGIES FOR GROWTH 12 DIFFERENTIATION VIA CLINICAL
PROFILES , .; 15 ENTERING THE MARKET QUICKLY 16 CONCLUSIONS 17 II. THE
INDUSTRY CHALLENGE: DO YOU REALLY WANT TO BE IN THIS BUSINESS? 19 HIGH
COMPLEXITY OF THE INDUSTRY 19 HOW ATTRACTIVE IS THE PHARMACEUTICAL
INDUSTRY? 22 FORCE 1: BARGAINING'POWER OF SUPPLIERS 24 FORCE 2:
BARGAINING POWER OF BUYERS 25 FORCE 3: RISK OF ENTRY FROM POTENTIAL
COMPETITORS 26 FORCE 4: THREAT OF SUBSTITUTE PRODUCTS 27 FORCE 5:
RIVALRY AMONG ESTABLISHED COMPANIES 28 FORCE 6: THE REGULATORS :.'.' 28
CONCLUSIONS 30 III. THE SCIENCE AND TECHNOLOGY CHALLENGE: HOW TO FIND
NEW DRUGS 33 RISE OF THE BIOTECHNOLOGY INDUSTRY: BOOSTING INNOVATION 33
HIGH-THROUGHPUT SCREENING: FAIL EARLIER, SUCCEED SOONER 38 COMBINATORIAL
CHEMISTRY: CUT EXPERIMENTAL CYCLE TIMES 39 BIOINFORMATICS: MORE THAN 100
GIGABYTES OF DATA PER DAY 40 PROTEOMICS: PROFITING FROM THE HUMAN GENOME
PROJECT 42 GENOMICS: TOWARDS INDIVIDUALIZATION AND MASS CUSTOMIZATION
.43 PHARMACOGENOMICS: CREATE TAILOR-MADE DRUGS 45 MOLECULAR DESIGN:
FROM EXPERIMENTING TO ANALYTIC DESIGN 47 CONCLUSIONS 48 XIV CONTENTS IV.
THE PIPELINE MANAGEMENT CHALLENGE: HOW TO ORGANIZE INNOVATION 51 THE
RELEVANCE OF PIPELINE MANAGEMENT 51 COMPLEXITY AND PHASES OF THE R&D
PROCESS 56 THE IMPORTANCE OF PROJECT AND PORTFOLIO MANAGEMENT 65 THE
DISAGGREGATION OF THE PHARMACEUTICAL VALUE CHAIN 68 IMPACT OF
OUTSOURCING ON PHARMACEUTICAL R&D 71 RISING IMPORTANCE OF R&D
COLLABORATIONS 75 RESEARCH ALLIANCES: ACCESSING EARLY-STAGE INNOVATION
78 IN-LICENSING:'ENHANCING THE INNOVATION PIPELINE 1 : 81
CO-DEVELOPMENT: MUTUALLY BENEFITING FROM JOINT RESOURCES, 83
OUT-LICENSING: COMMERCIALIZING INTERNAL RESEARCH RESULTS 86 HOW TO
COMMERCIALIZE A BREAKTHROUGH TECHNOLOGY 95 CONCLUSIONS 100 V. THE
INTERNATIONALIZATION CHALLENGE: WHERE TO GET ACCESS TO INNOVATION 103
TRENDS AND DRIVERS OF R&D INTERNATIONALIZATION 103 PRIMARY LOCATIONS OF
PHARMACEUTICAL R&D AROUND THE WORLD 108 NEW OPPORTUNITIES FOR DRUG
DEVELOPMENT IN CHINA.,- 111 THREE PRINCIPAL PROBLEMS OF DISPERSED R&D
117 CONCLUSIONS 121 VI. MANAGEMENT ANSWERS TO PHARMACEUTICAL R&D
CHALLENGES .123 MANAGING R&D ORGANIZATION AT ROCHE 123 MANAGING R&D
STRATEGY AT SCHERING 125 MANAGING THE RESEARCH-TO-DEVELOPMENT HANDOVER
AT ROCHE 127 MANAGING OUTSOURCING ACTIVITIES AT SOLVIAS. 130 MANAGING
INTELLECTUAL PROPERTY RIGHTS AT BAYER 133 MANAGING OUT-LICENSING
ATNOVARTIS 137 MANAGING UNCERTAINTY AT ROCHE 144 MANAGING GLOBAL R&D AT
MAJOR SWISS PHARMA COMPANIES 145 MANAGING A NICHE-MARKET STRATEGY AT
INTARCIA 151 MANAGING VIRTUAL PROJECT MANAGEMENT POOLS AT ROCHE 153
CONCLUSIONS , ., .156 VII. FUTURE DIRECTIONS AND TRENDS . *. 159
CONTENTS XV BIBLIOGRAPHY 165 INDEX 173 GLOSSARY '. 179 AUTHORS 185 |
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| author_role | aut aut aut |
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| index_date | 2024-07-02T20:14:39Z |
| indexdate | 2024-07-20T09:35:28Z |
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| isbn | 9783540776352 3540776354 |
| language | English |
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| publisher | Springer |
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| spelling | Gassmann, Oliver Verfasser aut Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz 2. ed. Berlin [u.a.] Springer 2008 XV, 186 S. graph. Darst., Kt. txt rdacontent n rdamedia nc rdacarrier Innovationswettbewerb (DE-588)4192032-6 gnd rswk-swf Arzneimittelmarkt (DE-588)4003131-7 gnd rswk-swf Marktentwicklung (DE-588)4123713-4 gnd rswk-swf Pharmazeutische Industrie (DE-588)4045696-1 gnd rswk-swf Erfolgsfaktor (DE-588)4197034-2 gnd rswk-swf Innovationsmanagement (DE-588)4161817-8 gnd rswk-swf Pharmazeutische Industrie (DE-588)4045696-1 s Innovationsmanagement (DE-588)4161817-8 s Erfolgsfaktor (DE-588)4197034-2 s DE-604 Arzneimittelmarkt (DE-588)4003131-7 s Innovationswettbewerb (DE-588)4192032-6 s Marktentwicklung (DE-588)4123713-4 s Reepmeyer, Gerrit Verfasser aut Zedtwitz, Maximilian von 1969- Verfasser (DE-588)120671417 aut text/html http://deposit.dnb.de/cgi-bin/dokserv?id=3077740&prov=M&dok_var=1&dok_ext=htm Inhaltstext GBV Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016403380&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Gassmann, Oliver Reepmeyer, Gerrit Zedtwitz, Maximilian von 1969- Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry Innovationswettbewerb (DE-588)4192032-6 gnd Arzneimittelmarkt (DE-588)4003131-7 gnd Marktentwicklung (DE-588)4123713-4 gnd Pharmazeutische Industrie (DE-588)4045696-1 gnd Erfolgsfaktor (DE-588)4197034-2 gnd Innovationsmanagement (DE-588)4161817-8 gnd |
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| title | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry |
| title_auth | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry |
| title_exact_search | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry |
| title_exact_search_txtP | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry |
| title_full | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz |
| title_fullStr | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz |
| title_full_unstemmed | Leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry Oliver Gassmann ; Gerrit Reepmeyer ; Maximilian von Zedtwitz |
| title_short | Leading pharmaceutical innovation |
| title_sort | leading pharmaceutical innovation trends and drivers for growth in the pharmaceutical industry |
| title_sub | trends and drivers for growth in the pharmaceutical industry |
| topic | Innovationswettbewerb (DE-588)4192032-6 gnd Arzneimittelmarkt (DE-588)4003131-7 gnd Marktentwicklung (DE-588)4123713-4 gnd Pharmazeutische Industrie (DE-588)4045696-1 gnd Erfolgsfaktor (DE-588)4197034-2 gnd Innovationsmanagement (DE-588)4161817-8 gnd |
| topic_facet | Innovationswettbewerb Arzneimittelmarkt Marktentwicklung Pharmazeutische Industrie Erfolgsfaktor Innovationsmanagement |
| url | http://deposit.dnb.de/cgi-bin/dokserv?id=3077740&prov=M&dok_var=1&dok_ext=htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016403380&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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