New antibiotic targets:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2008
|
| Schriftenreihe: | Methods in molecular medicine
142 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XI, 274 S. Ill., graph. Darst. |
| ISBN: | 9781588299154 |
Internformat
MARC
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| 245 | 1 | 0 | |a New antibiotic targets |c ed. by W. Scott Champney |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2008 | |
| 300 | |a XI, 274 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Methods in molecular medicine |v 142 | |
| 650 | 4 | |a Anti-Infective Agents |v Laboratory Manuals | |
| 650 | 4 | |a Anti-infective agents |x Testing | |
| 650 | 4 | |a Drug Delivery Systems |x methods |v Laboratory Manuals | |
| 650 | 4 | |a Drug Resistance, Microbial |v Laboratory Manuals | |
| 650 | 4 | |a Drug resistance in microorganisms | |
| 650 | 4 | |a Drug targeting | |
| 650 | 0 | 7 | |a Antibiotikum |0 (DE-588)4002257-2 |2 gnd |9 rswk-swf |
| 655 | 7 | |0 (DE-588)4143413-4 |a Aufsatzsammlung |2 gnd-content | |
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| 999 | |a oai:aleph.bib-bvb.de:BVB01-016373766 | ||
Datensatz im Suchindex
| _version_ | 1804137457531224064 |
|---|---|
| adam_text | Contents
Preface
...............................................................
v
Contributors
...........................................................
¡χ
1
Biocomputational Strategies for Microbial Drug Target Identification
Kishore R. Sakharkar, Meena K. Sakharkar,
and Vincent
Τ. Κ.
Chow
........................................ 1
2
Methods to Assay Inhibitors of
DNA Gyrase
and Topoisomerase
IV Activities
L. Mark Fisher and Xiao-Su Pan
................................... 11
3
A Method to Assay Inhibitors of
DNA
Polymerase
НІС
Activity
Michelle M. Butler and George E. Wright
......................... 25
4
Methods to Identify and Characterize Inhibitors of Bacterial
RNA
Polymerase
A. Simon Lynch and Qun
Du...................................... 37
5
Methods to Assay Inhibitors of tRNA Synthetase Activity
Dieter Beyer,
Hein
Peter
Kroll,
and
Heike Brötz-Oesterhelt....... 53
6
Three Methods to Assay Inhibitors of Ribosomal
Subunit
Assembly
W. Scott Champney
............................................... 63
7
Inhibition of Chaperone-Dependent Bacterial Ribosome Biogenesis
Abdalla
Al Ref
aii
and
Jean-Hervé Alix
............................. 75
8
Assays for the Identification of Inhibitors Targeting Specific
Translational Steps
Letìzia Brandì,
John Dresios, and
Claudio
О.
Gualerzi
............. 87
9
SPARK: A New Peptidyl
Transferase
Activity Assay
Alexander S.
Mankin
and
Norbert
Polaček........................
107
10
High-Throughput Screening of
Peptide Deformylase
Inhibitors
Kiet T. Nguyen and Dehua Pei
.................................... 117
11
A Method to Assay Penicillin-Binding Proteins
Michael J.
Pucci
and Thomas J. Dougherty
........................ 131
12
A Method to Assay Inhibitors of Lipopolysaccharide Synthesis
Marcy Hernick and Carol A. Fierke
............................... 143
vii
viii Contents
13
Methods for Assessing the Structure and Function of Cationic
Antimicrobial Peptides
Michelle Pate and Jack Blazyk
.................................... 755
14
Flow Cytometry of Bacterial Membrane Potential and Permeability
Howard M. Shapiro
...............................................
í
75
15
Bacterial Efflux Pump Inhibitors
Barbara J. Kamicker, Michael T. Sweeney, Frank Kaczmarek,
f
adia
Dib-Hajj,
Wenchi Shang, Kim Crimin, Joan Duignan,
and Thomas D. Gootz
..........................................187
16
Mycobacterium tuberculosis
ß-Ketoacyl Acyl
Carrier Protein
Synthase III (mtFabH) Assay: Principles and Method
Sarbjot Sachdeva and Kevin A. Reynolds
..........................205
17
Screening for Compounds That Affect the Interaction Between
Bacterial Two-Component Single Transduction Response
Regulator Protein and Cognate Promoter
DNA
Matthew G. Erickson, Andrew T. Ulijasz, and Bernard
Weisblum ..215
18
The Activity of rRNA Resistance Methyltransferases Assessed
by MALDI Mass Spectrometry
Stephen Douthwaite,
Rikke Lind
Jensen, and Finn Kirpekar
........223
19
Assays for
ß-Lactamase
Activity and Inhibition
Thammaiah Viswanatha, Laura
Marrone,
Valerie Goodfellow,
and Gary I. Dmitrienko
........................................239
20
Studies of Enzymes That Cause Resistance to Aminoglycoside
Antibiotics
Engin
H. Serpersu,
Can
Özén,
and Edward Wright
................261
Index
.................................................................273
|
| adam_txt |
Contents
Preface
.
v
Contributors
.
¡χ
1
Biocomputational Strategies for Microbial Drug Target Identification
Kishore R. Sakharkar, Meena K. Sakharkar,
and Vincent
Τ. Κ.
Chow
. 1
2
Methods to Assay Inhibitors of
DNA Gyrase
and Topoisomerase
IV Activities
L. Mark Fisher and Xiao-Su Pan
. 11
3
A Method to Assay Inhibitors of
DNA
Polymerase
НІС
Activity
Michelle M. Butler and George E. Wright
. 25
4
Methods to Identify and Characterize Inhibitors of Bacterial
RNA
Polymerase
A. Simon Lynch and Qun
Du. 37
5
Methods to Assay Inhibitors of tRNA Synthetase Activity
Dieter Beyer,
Hein
Peter
Kroll,
and
Heike Brötz-Oesterhelt. 53
6
Three Methods to Assay Inhibitors of Ribosomal
Subunit
Assembly
W. Scott Champney
. 63
7
Inhibition of Chaperone-Dependent Bacterial Ribosome Biogenesis
Abdalla
Al Ref
aii
and
Jean-Hervé Alix
. 75
8
Assays for the Identification of Inhibitors Targeting Specific
Translational Steps
Letìzia Brandì,
John Dresios, and
Claudio
О.
Gualerzi
. 87
9
SPARK: A New Peptidyl
Transferase
Activity Assay
Alexander S.
Mankin
and
Norbert
Polaček.
107
10
High-Throughput Screening of
Peptide Deformylase
Inhibitors
Kiet T. Nguyen and Dehua Pei
. 117
11
A Method to Assay Penicillin-Binding Proteins
Michael J.
Pucci
and Thomas J. Dougherty
. 131
12
A Method to Assay Inhibitors of Lipopolysaccharide Synthesis
Marcy Hernick and Carol A. Fierke
. 143
vii
viii Contents
13
Methods for Assessing the Structure and Function of Cationic
Antimicrobial Peptides
Michelle Pate and Jack Blazyk
. 755
14
Flow Cytometry of Bacterial Membrane Potential and Permeability
Howard M. Shapiro
.
í
75
15
Bacterial Efflux Pump Inhibitors
Barbara J. Kamicker, Michael T. Sweeney, Frank Kaczmarek,
f
adia
Dib-Hajj,
Wenchi Shang, Kim Crimin, Joan Duignan,
and Thomas D. Gootz
.187
16
Mycobacterium tuberculosis
ß-Ketoacyl Acyl
Carrier Protein
Synthase III (mtFabH) Assay: Principles and Method
Sarbjot Sachdeva and Kevin A. Reynolds
.205
17
Screening for Compounds That Affect the Interaction Between
Bacterial Two-Component Single Transduction Response
Regulator Protein and Cognate Promoter
DNA
Matthew G. Erickson, Andrew T. Ulijasz, and Bernard
Weisblum .215
18
The Activity of rRNA Resistance Methyltransferases Assessed
by MALDI Mass Spectrometry
Stephen Douthwaite,
Rikke Lind
Jensen, and Finn Kirpekar
.223
19
Assays for
ß-Lactamase
Activity and Inhibition
Thammaiah Viswanatha, Laura
Marrone,
Valerie Goodfellow,
and Gary I. Dmitrienko
.239
20
Studies of Enzymes That Cause Resistance to Aminoglycoside
Antibiotics
Engin
H. Serpersu,
Can
Özén,
and Edward Wright
.261
Index
.273 |
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| spelling | New antibiotic targets ed. by W. Scott Champney Totowa, NJ Humana Press 2008 XI, 274 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular medicine 142 Anti-Infective Agents Laboratory Manuals Anti-infective agents Testing Drug Delivery Systems methods Laboratory Manuals Drug Resistance, Microbial Laboratory Manuals Drug resistance in microorganisms Drug targeting Antibiotikum (DE-588)4002257-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Antibiotikum (DE-588)4002257-2 s DE-604 Champney W. Scott Sonstige oth Methods in molecular medicine 142 (DE-604)BV011334960 142 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016373766&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | New antibiotic targets Methods in molecular medicine Anti-Infective Agents Laboratory Manuals Anti-infective agents Testing Drug Delivery Systems methods Laboratory Manuals Drug Resistance, Microbial Laboratory Manuals Drug resistance in microorganisms Drug targeting Antibiotikum (DE-588)4002257-2 gnd |
| subject_GND | (DE-588)4002257-2 (DE-588)4143413-4 |
| title | New antibiotic targets |
| title_auth | New antibiotic targets |
| title_exact_search | New antibiotic targets |
| title_exact_search_txtP | New antibiotic targets |
| title_full | New antibiotic targets ed. by W. Scott Champney |
| title_fullStr | New antibiotic targets ed. by W. Scott Champney |
| title_full_unstemmed | New antibiotic targets ed. by W. Scott Champney |
| title_short | New antibiotic targets |
| title_sort | new antibiotic targets |
| topic | Anti-Infective Agents Laboratory Manuals Anti-infective agents Testing Drug Delivery Systems methods Laboratory Manuals Drug Resistance, Microbial Laboratory Manuals Drug resistance in microorganisms Drug targeting Antibiotikum (DE-588)4002257-2 gnd |
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