Bioinorganic chemistry: a short course
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| Format: | Book |
| Language: | English |
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Hoboken, NJ
Wiley-Intersience
2007
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| Edition: | 2. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XIX, 501 S., [8] Bl. Ill., graph. Darst. |
| ISBN: | 9780471761136 0471761133 |
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MARC
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| 100 | 1 | |a Roat-Malone, Rosette M. |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Bioinorganic chemistry |b a short course |c Rosette M. Roat-Malone |
| 250 | |a 2. ed. | ||
| 264 | 1 | |a Hoboken, NJ |b Wiley-Intersience |c 2007 | |
| 300 | |a XIX, 501 S., [8] Bl. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
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| 650 | 4 | |a Biochemistry | |
| 650 | 4 | |a Bioinorganic chemistry | |
| 650 | 4 | |a Chemistry, Bioinorganic | |
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Record in the Search Index
| _version_ | 1804137241916735488 |
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| adam_text | CONTENTS
Preface xiii
Acknowledgments xix
1 Inorganic Chemistry Essentials 1
1.1 Introduction, 1
1.2 Essential Chemical Elements, 1
1.3 Metals in Biological Systems: A Survey, 3
1.4 Inorganic Chemistry Basics, 6
1.5 Biological Metal Ion Complexation, 8
1.5.1 Thermodynamics, 8
1.5.2 Kinetics, 9
1.6 Electronic and Geometrie Structures of Metals in
Biological Systems, 13
1.7 Bioorganometallic Chemistry, 19
1.8 Electron Transfer, 22
1.9 Conclusions, 26
References, 27
2 Biochemistry Fundamentals 29
2.1 Introduction, 29
2.2 Proteins, 30
2.2.1 Amino Acid Building Blocks, 30
2.2.2 Protein Structure, 33
vii
^j. CONTENTS
2.2.3 Protein Sequencing and Proteomics, 39
2.2.4 Protein Function, Enzymes, and Enzyme Kinetics, 43
2.3 Nucleic Acids, 47
2.3.1 DNA and RNA Building Blocks, 47
2.3.2 DNA and RNA Molecular Structures, 47
2.3.3 Transmission of Genetic Information, 53
2.3.4 Genetic Mutations and Site Directed Mutagenesis, 56
2.3.5 Genes and Cloning, 58
2.3.6 Genomics and the Human Genome, 61
2.4 Zinc Finger Proteins, 63
2.4.1 Descriptive Examples, 67
2.5 Summary and Conclusions, 73
References, 74
3 Instrumental Methods
3.1 Introduction, 76
3.1.1 Analytical Instrument Based Methods, 76
3.1.2 Spectroscopy, 77
3.2 X Ray Absorption Spectroscopy (XAS) and Extended X Ray
Absorption Fine Structure (EXAFS), 78
3.2.1 Theoretical Aspects and Hardware, 78
3.2.2 Descriptive Examples, 81
3.3 X Ray Crystallography, 83
3.3.1 Introduction, 83
3.3.2 Crystallization and Crystal Habits, 84
3.3.3 Theory and Hardware, 88
3.3.4 Descriptive Examples, 95
3.4 Nuclear Magnetic Resonance, 98
3.4.1 Theoretical Aspects, 98
3.4.2 Nuclear Screening and the Chemical Shift, 101
3.4.3 Spin Spin Coupling, 104
3.4.4 Techniques of Spectral Integration and Spin Spin
Decoupling, 106
3.4.5 Nuclear Magnetic Relaxation, 107
3.4.6 The Nuclear Overhauser Effect (NOE), 108
3.4.7 Obtaining the NMR Spectrum, 110
3.4.8 Two Dimensional (2D) NMR Spectroscopy, 111
3.4.9 Two Dimensional Correlation Spectroscopy (COSY) and
Total Correlation Spectroscopy (TOCSY), 112
3.4.10 Nuclear Overhauser Effect Spectroscopy (NOESY), 115 i
3.4.11 Multidimensional NMR, 116
3.4.12 Descriptive Examples, 117
3.5 Electron Paramagnetic Resonance, 122
3.5.1 Theory and Determination of g Values, 122
CONTENTS ix
3.5.2 Hyperfine and Superhyperfine Interactions, 127
3.5.3 Electron Nuclear Double Resonance (ENDOR)
and Electron Spin Echo Envelope Modulation
(ESEEM), 129
3.5.4 Descriptive Examples, 129
3.6 Mössbauer Spectroscopy, 132
3.6.1 Theoretical Aspects, 132
3.6.2 Quadrupole Splitting and the Isomer Shift, 134
3.6.3 Magnetic Hyperfine Interactions, 136
3.6.4 Descriptive Examples, 137
3.7 Other Instrumental Methods, 139
3.7.1 Atomic Force Microscopy, 139
3.7.2 Fast and Time Resolved Methods, 143
3.7.2.1 Stopped Flow Kinetic Methods, 143
3.7.2.2 Flash Photolysis, 144
3.7.2.3 Time Resolved Crystallography, 146
3.7.3 Mass Spectrometry, 148
3.8 Summary and Conclusions, 153
References, 154
4 Computer Hardware, Software, and Computational
Chemistry Methods 157
4.1 Introduction to Computer Based Methods, 157
4.2 Computer Hardware, 157
4.3 Molecular Modeling and Molecular Mechanics, 160
4.3.1 Introduction to MM, 160
4.3.2 Molecular Modeling, Molecular Mechanics,
and Molecular Dynamics, 161
4.3.3 Biomolecule Modeling, 166
4.3.4 A Molecular Modeling Descriptive Example, 167
4.4 Quantum Mechanics Based Computational Methods, 170
4.4.1 Introduction, 170
4.4.2 Ab Initio Methods, 170
4.4.3 Density Function Theory, 171
4.4.4 Semiempirical Methods, 173
4.5 Computer Software for Chemistry, 174
4.5.1 Mathematical Software, 180
4.6 World Wide Web Online Resources, 181
4.6.1 Nomenclature and Visualization Resources, 181
4.6.2 Online Societies, Online Literature Searching, and Materials
and Equipment Websites, 183
4.7 Summary and Conclusions, 185
References, 185
x CONTENTS
5 Group I and II Metals in Biological Systems: Homeostasis and
Group I Biomolecules ™
5.1 Introduction, 189
5.2 Homeostasis of Metals (and Some Nonmetals), 192
5.2.1 Phosphorus as Phosphate, 192
5.2.2 Potassium, Sodium, and Chloride Ions, 193
5.2.3 Calcium Homeostasis, 194
5.3 Movement of Molecules and Ions Across Membranes, 195
5.3.1 Passive Diffusion, 195
5.3.2 Facilitated Diffusion, 197
5.3.2.1 Gated Channels, 197
5.3.3 Active Transport—Ion Pumps, 197
5.4 Potassium Dependent Molecules, 199
5.4.1 Na+/K+ ATPase: The Sodium Pump, 199
5.4.2 Potassium (K+) Ion Channels, 203
5.4.2.1 Introduction, 203
5.4.2.2 X Ray Crystallographic Studies, 205
5.5 Conclusions, 235
References, 235
6 Group I and II Metals in Biological Systems: Group II 238
6.1 Introduction, 238
6.2 Magnesium and Catalytic RNA, 238
6.2.1 Introduction, 238
6.2.2 Analyzing the Role of the Metal Ion, 241
6.2.3 The Group I Intron Ribozyme, 244
6.2.4 The Hammerhead Ribozyme 261
6.3 Calcium Dependent Molecules, 301
6.3.1 Introduction, 301
6.3.2 Calmodulin, 302
6.3.2.1 Introduction, 302
6.3.2.2 Calmodulin Structure by X Ray and
NMR, 303
6.3.2.3 Calmodulin Interactions with Drug
Molecules, 308
6.3.2.4 Calmodulin Peptide Binding, 313
6.3.2.5 Conclusions, 326
6.4 Phosphoryl Transfer: P Type ATPases, 327
6.4.1 Introduction, 327
6.4.2 Calcium P Type ATPases, 327
6A.2A Ca2+ ATPase Protein SERCAla and f
the Ca2+ ATPase Cycle, 329 I
6.5 Conclusions, 337 I
References, 338 I
CONTENTS xi
7 Iron Containing Proteins and Enzymes 343
7.1 Introduction: Iron Containing Proteins with Porphyrin
Ligand Systems, 343
7.2 Myoglobin and Hemoglobin, 343
7.2.1 Myoglobin and Hemoglobin Basics, 345
7.2.2 Structure of the Heme Prosthetic Group, 347
7.2.3 Behavior of Dioxygen Bound to Metals, 348
7.2.4 Structure of the Active Site in Myoglobin and Hemoglobin:
Comparison to Model Compounds, 349
7.2.5 Some Notes on Model Compounds, 352
7.2.6 Iron Containing Model Compounds, 353
7.2.7 Binding of CO to Myoglobin, Hemoglobin,
and Model Compounds, 356
7.2.8 Conclusions, 359
7.3 Introduction to Cytochromes, 359
7.4 Cytochrome P450: A Monooxygenase, 361
7.4.1 Introduction, 361
7.4.2 Cytochrome P450: Structure and Function, 363
7.4.3 Cytochrome P450: Mechanism of Activity, 365
7.4.4 Analytical Methods: X Ray Crystallography, 369
7.4.5 Cytochrome P450 Model Compounds, 372
7.4.5.1 Introduction, 372
7.4.5.2 A Cytochrome P450 Model Compound:
Structural, 372
7.4.5.3 Cytochrome P450 Model Compounds:
Functional, 374
7.4.6 Cytochrome P450 Conclusions, 382
7.5 Cytochrome b(6)f: A Green Plant Cytochrome, 382
7.5.1 Introduction, 382
7.5.2 Cytochrome b(6)f Metal Cofactor Specifics, 386
7.6 Cytochrome bc,: A Bacterial Cytochrome, 388
7.6.1 Introduction, 388
7.6.2 Cytochrome bc, Structure, 389
7.6.3 Cytochrome bei Metal Cofactor Specifics, 391
7.6.4 The Cytochrome bc, Q Cycle, 395
7.6.5 Cytochrome bc, Inhibitors, 397
7.6.6 Cytochrome bc, Conclusions, 408
7.7 Cytochromes c, 408
7.7.1 Introduction, 408
7.7.2 Mitochondrial Cytochrome c (Yeast), 411
7.7.3 Mitochondrial Cytochrome c (Horse), 416
7.7.4 Cytochrome c Folding, Electron Transfer,
and Cell Apoptosis, 422
7.7.4.1 Cytochrome c Folding, 422
xü CONTENTS
7.7.4.2 Electron Transfer in Cytochrome c and Its Redox
Partners, 424
7.7.4.3 Apoptosis, 427
7.7.5 Cytochrome c Conclusions, 429
7.8 Cytochrome c Oxidase, 429
7.8.1 Introduction, 429
7.8.2 Metal Binding Sites in Cytochrome c Oxidase, 432
7.8.3 Dioxygen Binding, Proton Translocation,
and Electron Transport, 434
7.8.4 Cytochrome c Oxidase Model Compounds and Associated
Analytical Techniques, 440
7.8.5 Cytochrome c Oxidase Conclusions, 453
7.9 Non Heme Iron Containing Proteins, 454
7.9.1 Introduction, 454
7.9.2 Proteins with Iron Sulfur Clusters, 454
7.9.2.1 The Enzyme Aconitase 455
7.9.3 Iron Oxo Proteins, 458
7.9.3.1 Methane Monooxygenases 459
7.10 Conclusions, 465
References, 466
Index 477
|
| adam_txt |
CONTENTS
Preface xiii
Acknowledgments xix
1 Inorganic Chemistry Essentials 1
1.1 Introduction, 1
1.2 Essential Chemical Elements, 1
1.3 Metals in Biological Systems: A Survey, 3
1.4 Inorganic Chemistry Basics, 6
1.5 Biological Metal Ion Complexation, 8
1.5.1 Thermodynamics, 8
1.5.2 Kinetics, 9
1.6 Electronic and Geometrie Structures of Metals in
Biological Systems, 13
1.7 Bioorganometallic Chemistry, 19
1.8 Electron Transfer, 22
1.9 Conclusions, 26
References, 27
2 Biochemistry Fundamentals 29
2.1 Introduction, 29
2.2 Proteins, 30
2.2.1 Amino Acid Building Blocks, 30
2.2.2 Protein Structure, 33
vii
^j. CONTENTS
2.2.3 Protein Sequencing and Proteomics, 39
2.2.4 Protein Function, Enzymes, and Enzyme Kinetics, 43
2.3 Nucleic Acids, 47
2.3.1 DNA and RNA Building Blocks, 47
2.3.2 DNA and RNA Molecular Structures, 47
2.3.3 Transmission of Genetic Information, 53
2.3.4 Genetic Mutations and Site Directed Mutagenesis, 56
2.3.5 Genes and Cloning, 58
2.3.6 Genomics and the Human Genome, 61
2.4 Zinc Finger Proteins, 63
2.4.1 Descriptive Examples, 67
2.5 Summary and Conclusions, 73
References, 74
3 Instrumental Methods
3.1 Introduction, 76
3.1.1 Analytical Instrument Based Methods, 76
3.1.2 Spectroscopy, 77
3.2 X Ray Absorption Spectroscopy (XAS) and Extended X Ray
Absorption Fine Structure (EXAFS), 78
3.2.1 Theoretical Aspects and Hardware, 78
3.2.2 Descriptive Examples, 81
3.3 X Ray Crystallography, 83
3.3.1 Introduction, 83
3.3.2 Crystallization and Crystal Habits, 84
3.3.3 Theory and Hardware, 88
3.3.4 Descriptive Examples, 95
3.4 Nuclear Magnetic Resonance, 98
3.4.1 Theoretical Aspects, 98
3.4.2 Nuclear Screening and the Chemical Shift, 101
3.4.3 Spin Spin Coupling, 104
3.4.4 Techniques of Spectral Integration and Spin Spin
Decoupling, 106
3.4.5 Nuclear Magnetic Relaxation, 107
3.4.6 The Nuclear Overhauser Effect (NOE), 108
3.4.7 Obtaining the NMR Spectrum, 110
3.4.8 Two Dimensional (2D) NMR Spectroscopy, 111
3.4.9 Two Dimensional Correlation Spectroscopy (COSY) and
Total Correlation Spectroscopy (TOCSY), 112
3.4.10 Nuclear Overhauser Effect Spectroscopy (NOESY), 115 i
3.4.11 Multidimensional NMR, 116 \
3.4.12 Descriptive Examples, 117
3.5 Electron Paramagnetic Resonance, 122
3.5.1 Theory and Determination of g Values, 122
CONTENTS ix
3.5.2 Hyperfine and Superhyperfine Interactions, 127
3.5.3 Electron Nuclear Double Resonance (ENDOR)
and Electron Spin Echo Envelope Modulation
(ESEEM), 129
3.5.4 Descriptive Examples, 129
3.6 Mössbauer Spectroscopy, 132
3.6.1 Theoretical Aspects, 132
3.6.2 Quadrupole Splitting and the Isomer Shift, 134
3.6.3 Magnetic Hyperfine Interactions, 136
3.6.4 Descriptive Examples, 137
3.7 Other Instrumental Methods, 139
3.7.1 Atomic Force Microscopy, 139
3.7.2 Fast and Time Resolved Methods, 143
3.7.2.1 Stopped Flow Kinetic Methods, 143
3.7.2.2 Flash Photolysis, 144
3.7.2.3 Time Resolved Crystallography, 146
3.7.3 Mass Spectrometry, 148
3.8 Summary and Conclusions, 153
References, 154
4 Computer Hardware, Software, and Computational
Chemistry Methods 157
4.1 Introduction to Computer Based Methods, 157
4.2 Computer Hardware, 157
4.3 Molecular Modeling and Molecular Mechanics, 160
4.3.1 Introduction to MM, 160
4.3.2 Molecular Modeling, Molecular Mechanics,
and Molecular Dynamics, 161
4.3.3 Biomolecule Modeling, 166
4.3.4 A Molecular Modeling Descriptive Example, 167
4.4 Quantum Mechanics Based Computational Methods, 170
4.4.1 Introduction, 170
4.4.2 Ab Initio Methods, 170
4.4.3 Density Function Theory, 171
4.4.4 Semiempirical Methods, 173
4.5 Computer Software for Chemistry, 174
4.5.1 Mathematical Software, 180
4.6 World Wide Web Online Resources, 181
4.6.1 Nomenclature and Visualization Resources, 181
4.6.2 Online Societies, Online Literature Searching, and Materials
and Equipment Websites, 183
4.7 Summary and Conclusions, 185
References, 185
x CONTENTS
5 Group I and II Metals in Biological Systems: Homeostasis and
Group I Biomolecules ™"
5.1 Introduction, 189
5.2 Homeostasis of Metals (and Some Nonmetals), 192
5.2.1 Phosphorus as Phosphate, 192
5.2.2 Potassium, Sodium, and Chloride Ions, 193
5.2.3 Calcium Homeostasis, 194
5.3 Movement of Molecules and Ions Across Membranes, 195
5.3.1 Passive Diffusion, 195
5.3.2 Facilitated Diffusion, 197
5.3.2.1 Gated Channels, 197
5.3.3 Active Transport—Ion Pumps, 197
5.4 Potassium Dependent Molecules, 199
5.4.1 Na+/K+ ATPase: The Sodium Pump, 199
5.4.2 Potassium (K+) Ion Channels, 203
5.4.2.1 Introduction, 203
5.4.2.2 X Ray Crystallographic Studies, 205
5.5 Conclusions, 235
References, 235
6 Group I and II Metals in Biological Systems: Group II 238
6.1 Introduction, 238
6.2 Magnesium and Catalytic RNA, 238
6.2.1 Introduction, 238
6.2.2 Analyzing the Role of the Metal Ion, 241
6.2.3 The Group I Intron Ribozyme, 244
6.2.4 The Hammerhead Ribozyme 261
6.3 Calcium Dependent Molecules, 301
6.3.1 Introduction, 301
6.3.2 Calmodulin, 302
6.3.2.1 Introduction, 302
6.3.2.2 Calmodulin Structure by X Ray and
NMR, 303
6.3.2.3 Calmodulin Interactions with Drug
Molecules, 308
6.3.2.4 Calmodulin Peptide Binding, 313
6.3.2.5 Conclusions, 326
6.4 Phosphoryl Transfer: P Type ATPases, 327
6.4.1 Introduction, 327
6.4.2 Calcium P Type ATPases, 327 \
6A.2A Ca2+ ATPase Protein SERCAla and f
the Ca2+ ATPase Cycle, 329 I
6.5 Conclusions, 337 I
References, 338 I
CONTENTS xi
7 Iron Containing Proteins and Enzymes 343
7.1 Introduction: Iron Containing Proteins with Porphyrin
Ligand Systems, 343
7.2 Myoglobin and Hemoglobin, 343
7.2.1 Myoglobin and Hemoglobin Basics, 345
7.2.2 Structure of the Heme Prosthetic Group, 347
7.2.3 Behavior of Dioxygen Bound to Metals, 348
7.2.4 Structure of the Active Site in Myoglobin and Hemoglobin:
Comparison to Model Compounds, 349
7.2.5 Some Notes on Model Compounds, 352
7.2.6 Iron Containing Model Compounds, 353
7.2.7 Binding of CO to Myoglobin, Hemoglobin,
and Model Compounds, 356
7.2.8 Conclusions, 359
7.3 Introduction to Cytochromes, 359
7.4 Cytochrome P450: A Monooxygenase, 361
7.4.1 Introduction, 361
7.4.2 Cytochrome P450: Structure and Function, 363
7.4.3 Cytochrome P450: Mechanism of Activity, 365
7.4.4 Analytical Methods: X Ray Crystallography, 369
7.4.5 Cytochrome P450 Model Compounds, 372
7.4.5.1 Introduction, 372
7.4.5.2 A Cytochrome P450 Model Compound:
Structural, 372
7.4.5.3 Cytochrome P450 Model Compounds:
Functional, 374
7.4.6 Cytochrome P450 Conclusions, 382
7.5 Cytochrome b(6)f: A Green Plant Cytochrome, 382
7.5.1 Introduction, 382
7.5.2 Cytochrome b(6)f Metal Cofactor Specifics, 386
7.6 Cytochrome bc,: A Bacterial Cytochrome, 388
7.6.1 Introduction, 388
7.6.2 Cytochrome bc, Structure, 389
7.6.3 Cytochrome bei Metal Cofactor Specifics, 391
7.6.4 The Cytochrome bc, Q Cycle, 395
7.6.5 Cytochrome bc, Inhibitors, 397
7.6.6 Cytochrome bc, Conclusions, 408
7.7 Cytochromes c, 408
7.7.1 Introduction, 408
7.7.2 Mitochondrial Cytochrome c (Yeast), 411
7.7.3 Mitochondrial Cytochrome c (Horse), 416
7.7.4 Cytochrome c Folding, Electron Transfer,
and Cell Apoptosis, 422
7.7.4.1 Cytochrome c Folding, 422
xü CONTENTS
7.7.4.2 Electron Transfer in Cytochrome c and Its Redox
Partners, 424
7.7.4.3 Apoptosis, 427
7.7.5 Cytochrome c Conclusions, 429
7.8 Cytochrome c Oxidase, 429
7.8.1 Introduction, 429
7.8.2 Metal Binding Sites in Cytochrome c Oxidase, 432
7.8.3 Dioxygen Binding, Proton Translocation,
and Electron Transport, 434
7.8.4 Cytochrome c Oxidase Model Compounds and Associated
Analytical Techniques, 440
7.8.5 Cytochrome c Oxidase Conclusions, 453
7.9 Non Heme Iron Containing Proteins, 454
7.9.1 Introduction, 454
7.9.2 Proteins with Iron Sulfur Clusters, 454
7.9.2.1 The Enzyme Aconitase 455
7.9.3 Iron Oxo Proteins, 458
7.9.3.1 Methane Monooxygenases 459
7.10 Conclusions, 465
References, 466
Index 477 |
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| author | Roat-Malone, Rosette M. |
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| edition | 2. ed. |
| format | Book |
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| id | DE-604.BV023021737 |
| illustrated | Illustrated |
| index_date | 2024-07-02T19:13:25Z |
| indexdate | 2024-07-09T21:09:10Z |
| institution | BVB |
| isbn | 9780471761136 0471761133 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-016225783 |
| oclc_num | 126230917 |
| open_access_boolean | |
| owner | DE-92 DE-91G DE-BY-TUM DE-703 DE-19 DE-BY-UBM DE-1102 DE-11 DE-29T DE-355 DE-BY-UBR |
| owner_facet | DE-92 DE-91G DE-BY-TUM DE-703 DE-19 DE-BY-UBM DE-1102 DE-11 DE-29T DE-355 DE-BY-UBR |
| physical | XIX, 501 S., [8] Bl. Ill., graph. Darst. |
| publishDate | 2007 |
| publishDateSearch | 2007 |
| publishDateSort | 2007 |
| publisher | Wiley-Intersience |
| record_format | marc |
| spelling | Roat-Malone, Rosette M. Verfasser aut Bioinorganic chemistry a short course Rosette M. Roat-Malone 2. ed. Hoboken, NJ Wiley-Intersience 2007 XIX, 501 S., [8] Bl. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Biochemistry Bioinorganic chemistry Chemistry, Bioinorganic Bioanorganische Chemie (DE-588)4126727-8 gnd rswk-swf Bioanorganische Chemie (DE-588)4126727-8 s DE-604 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016225783&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Roat-Malone, Rosette M. Bioinorganic chemistry a short course Biochemistry Bioinorganic chemistry Chemistry, Bioinorganic Bioanorganische Chemie (DE-588)4126727-8 gnd |
| subject_GND | (DE-588)4126727-8 |
| title | Bioinorganic chemistry a short course |
| title_auth | Bioinorganic chemistry a short course |
| title_exact_search | Bioinorganic chemistry a short course |
| title_exact_search_txtP | Bioinorganic chemistry a short course |
| title_full | Bioinorganic chemistry a short course Rosette M. Roat-Malone |
| title_fullStr | Bioinorganic chemistry a short course Rosette M. Roat-Malone |
| title_full_unstemmed | Bioinorganic chemistry a short course Rosette M. Roat-Malone |
| title_short | Bioinorganic chemistry |
| title_sort | bioinorganic chemistry a short course |
| title_sub | a short course |
| topic | Biochemistry Bioinorganic chemistry Chemistry, Bioinorganic Bioanorganische Chemie (DE-588)4126727-8 gnd |
| topic_facet | Biochemistry Bioinorganic chemistry Chemistry, Bioinorganic Bioanorganische Chemie |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016225783&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT roatmalonerosettem bioinorganicchemistryashortcourse |