The proteasome in neurodegeneration:
Gespeichert in:
| Format: | Elektronisch E-Book |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
New York, NY
Springer
2006
|
| Schlagworte: | |
| Online-Zugang: | DE-355 Volltext Inhaltsverzeichnis |
| Beschreibung: | 1 Online-Ressource |
| ISBN: | 9780387284996 9780387285009 |
| DOI: | 10.1007/0-387-28500-8 |
Internformat
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Datensatz im Suchindex
| _version_ | 1817718708241432576 |
|---|---|
| adam_text |
CONTENTS
CONTRIBUTORS v
PREFACE ix
PART I: BASIC ASPECTS OF PROTEIN DEGRADATION THROUGH
THE UBIQUITIN PROTEASOME SYSTEM (UPS)
1. YEAST PROTEASOME STRUCTURE AND BIOGENESIS 1
Cordula Enenkel
2. UBIQUITIN PROTEASOME FUNCTION IN THE
CENTRAL NERVOUS SYSTEM 17
Qunxing Ding and Jeffrey N. Keller
PART II: PROTEIN AGGREGATION. INCLUSION FORMATION AND
UPS FUNCTION
3. PROTEIN AGGREGATION AND THE UPS: A TWO WAY STREET V)
Kostas Vekrellis and Lconidas Slcfanis
4. IMPACT OF INCLUSION FORMATION ON CELL SURVIVAL 57
M. Maral Mouradian. Mikiei Tanaka. Gwang Lee. and Eunsung Junn
5. INCLUSION FORMATION AND DISSOLUTION
FOLLOWING PROTEASOMAL INHIBITION IN
NEURONAL CELLS 69
Lconidas Stefanis and Hardy J. Rideout
xiv CONTENTS
PART III: OXIDAT1VE STRESS AND UPS FUNCTION
6. THE PROTEASOME: BOTH A SOURCE AND A TARGET
OF OXIDATIVE STRESS? 85
Barry Halliwell
7. INFLAMMATION AS A MEDIATOR OF OXIDATIVE STRESS AND
UPS DYSFUNCTION 105
Thomas Schmidt Glenewinkel and Maria Figueiredo Pereira
PART IV: PROTEASOME AND NEURONAL CELL DEATH AND SURVIVAL
8. ROLE OF THE UBIQUITIN PROTEASOME SYSTEM DURING
NEURONAL CELL DEATH 133
Nadia Canu and Pietro Calissano
9. MECHANISMS OF NEURONAL DEATH INDUCED BY
PROTEASOMAL INHIBITION 149
Isabclle Lang Rollin and Leonidas Stefanis
PART V: MODELS OF DYSFUNCTION OF THE UPS AND
THE PROTEASOME
10. PHARMACOLOGICAL AND MOLECULAR MODELS OF
PROTEASOMAL DYSFUNCTION 167
Thomas Schmidt Glenewinkel and Maria Figuierdo Pereira
11. THE GAD MOUSE: A WINDOW INTO UPS RELATED
NEURODEGENERATION AND THL FUNCTION OF THE
DEUBIQUITINATING ENZYME UCH L1 185
Jungkee Kvvon and Keiji Wada
PART VI: THE UPS IN NEURODEGENERATIVE DISEASES AND AGING
12. PARKINSON'S DISEASE AND RELATED DISORDERS 199
Mark Cookson
13. I'BIQUITINATION BY PARKIN IMPLICATIONS IN PARKINSON'S
DISEASE 213
Salhva Ruvichandran. Ted M. Dawson. and Valina L. Dawson
14. HUNTINGTON'S DISEASE 225
M. Diaz Hernandez and J. .1. Lucas
15. I RAMESHIFT UBIQUITIN MUTANT IN ALZHEIMER'S DISEASE
AND OTHER NEURODEGENERATIVE DISORDERS 237
Robert Layficld
1(. MOTOR NEURON DISEASE 247
Heather D. Durham. Edor Kabashi. David M. Taylor, and Jeffrey N. A car
CONTENTS xv
17. THE PARADOXICAL ROLE OF PROTEASOMES
IN PRION DISEASES 265
Neena Singh, Yaping Gu, Sharmila Bose, Subhabrata Basu, Xiu Luo,
Ajitesh Ojha, and Richa Mishra
18. AGING AND THE PROTEASOME 285
Qunxing Ding and Jeffrey N. Keller
INDEX 299 |
| adam_txt |
CONTENTS
CONTRIBUTORS v
PREFACE ix
PART I: BASIC ASPECTS OF PROTEIN DEGRADATION THROUGH
THE UBIQUITIN PROTEASOME SYSTEM (UPS)
1. YEAST PROTEASOME STRUCTURE AND BIOGENESIS 1
Cordula Enenkel
2. UBIQUITIN PROTEASOME FUNCTION IN THE
CENTRAL NERVOUS SYSTEM 17
Qunxing Ding and Jeffrey N. Keller
PART II: PROTEIN AGGREGATION. INCLUSION FORMATION AND
UPS FUNCTION
3. PROTEIN AGGREGATION AND THE UPS: A TWO WAY STREET V)
Kostas Vekrellis and Lconidas Slcfanis
4. IMPACT OF INCLUSION FORMATION ON CELL SURVIVAL 57
M. Maral Mouradian. Mikiei Tanaka. Gwang Lee. and Eunsung Junn
5. INCLUSION FORMATION AND DISSOLUTION
FOLLOWING PROTEASOMAL INHIBITION IN
NEURONAL CELLS 69
Lconidas Stefanis and Hardy J. Rideout
xiv CONTENTS
PART III: OXIDAT1VE STRESS AND UPS FUNCTION
6. THE PROTEASOME: BOTH A SOURCE AND A TARGET
OF OXIDATIVE STRESS? 85
Barry Halliwell
7. INFLAMMATION AS A MEDIATOR OF OXIDATIVE STRESS AND
UPS DYSFUNCTION 105
Thomas Schmidt Glenewinkel and Maria Figueiredo Pereira
PART IV: PROTEASOME AND NEURONAL CELL DEATH AND SURVIVAL
8. ROLE OF THE UBIQUITIN PROTEASOME SYSTEM DURING
NEURONAL CELL DEATH 133
Nadia Canu and Pietro Calissano
9. MECHANISMS OF NEURONAL DEATH INDUCED BY
PROTEASOMAL INHIBITION 149
Isabclle Lang Rollin and Leonidas Stefanis
PART V: MODELS OF DYSFUNCTION OF THE UPS AND
THE PROTEASOME
10. PHARMACOLOGICAL AND MOLECULAR MODELS OF
PROTEASOMAL DYSFUNCTION 167
Thomas Schmidt Glenewinkel and Maria Figuierdo Pereira
11. THE GAD MOUSE: A WINDOW INTO UPS RELATED
NEURODEGENERATION AND THL FUNCTION OF THE
DEUBIQUITINATING ENZYME UCH L1 185
Jungkee Kvvon and Keiji Wada
PART VI: THE UPS IN NEURODEGENERATIVE DISEASES AND AGING
12. PARKINSON'S DISEASE AND RELATED DISORDERS 199
Mark Cookson
13. I'BIQUITINATION BY PARKIN IMPLICATIONS IN PARKINSON'S
DISEASE 213
Salhva Ruvichandran. Ted M. Dawson. and Valina L. Dawson
14. HUNTINGTON'S DISEASE 225
M. Diaz Hernandez and J. .1. Lucas
15. I RAMESHIFT UBIQUITIN MUTANT IN ALZHEIMER'S DISEASE
AND OTHER NEURODEGENERATIVE DISORDERS 237
Robert Layficld
1(. MOTOR NEURON DISEASE 247
Heather D. Durham. Edor Kabashi. David M. Taylor, and Jeffrey N. A car
CONTENTS xv
17. THE PARADOXICAL ROLE OF PROTEASOMES
IN PRION DISEASES 265
Neena Singh, Yaping Gu, Sharmila Bose, Subhabrata Basu, Xiu Luo,
Ajitesh Ojha, and Richa Mishra
18. AGING AND THE PROTEASOME 285
Qunxing Ding and Jeffrey N. Keller
INDEX 299 |
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| doi_str_mv | 10.1007/0-387-28500-8 |
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| index_date | 2024-07-02T19:08:37Z |
| indexdate | 2024-12-06T19:00:45Z |
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| isbn | 9780387284996 9780387285009 |
| language | English |
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| publishDate | 2006 |
| publishDateSearch | 2006 |
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| publisher | Springer |
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| spelling | The proteasome in neurodegeneration ed. by Leonidas Stefanis ... New York, NY Springer 2006 1 Online-Ressource txt rdacontent c rdamedia cr rdacarrier Proteasom (DE-588)4315827-4 gnd rswk-swf Nervendegeneration (DE-588)4300182-8 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Nervendegeneration (DE-588)4300182-8 s Proteasom (DE-588)4315827-4 s b DE-604 Stefanis, Leonidas Sonstige oth Erscheint auch als Druck-Ausgabe, Hardcover 0-387-28499-0 https://doi.org/10.1007/0-387-28500-8 Verlag Volltext HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016213219&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | The proteasome in neurodegeneration Proteasom (DE-588)4315827-4 gnd Nervendegeneration (DE-588)4300182-8 gnd |
| subject_GND | (DE-588)4315827-4 (DE-588)4300182-8 (DE-588)4143413-4 |
| title | The proteasome in neurodegeneration |
| title_auth | The proteasome in neurodegeneration |
| title_exact_search | The proteasome in neurodegeneration |
| title_exact_search_txtP | The proteasome in neurodegeneration |
| title_full | The proteasome in neurodegeneration ed. by Leonidas Stefanis ... |
| title_fullStr | The proteasome in neurodegeneration ed. by Leonidas Stefanis ... |
| title_full_unstemmed | The proteasome in neurodegeneration ed. by Leonidas Stefanis ... |
| title_short | The proteasome in neurodegeneration |
| title_sort | the proteasome in neurodegeneration |
| topic | Proteasom (DE-588)4315827-4 gnd Nervendegeneration (DE-588)4300182-8 gnd |
| topic_facet | Proteasom Nervendegeneration Aufsatzsammlung |
| url | https://doi.org/10.1007/0-387-28500-8 http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016213219&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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