Glial neurobiology: a textbook
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| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Chichester [u.a.]
Wiley
2007
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XIV, 215 S. Ill., graph. Darst. |
| ISBN: | 9780470015643 9780470517406 |
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MARC
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| 100 | 1 | |a Verkhratsky, Alexej |e Verfasser |4 aut | |
| 245 | 1 | 0 | |a Glial neurobiology |b a textbook |c Alexei Verkhratsky ; Arthur Butt |
| 264 | 1 | |a Chichester [u.a.] |b Wiley |c 2007 | |
| 300 | |a XIV, 215 S. |b Ill., graph. Darst. | ||
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| 338 | |b nc |2 rdacarrier | ||
| 650 | 4 | |a Glia | |
| 650 | 4 | |a Neuroglia | |
| 650 | 4 | |a Neurophysiologie | |
| 650 | 4 | |a Neuroglia | |
| 700 | 1 | |a Butt, Arthur |e Verfasser |4 aut | |
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Record in the Search Index
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|---|---|
| adam_text | Contents
Preface xi
List of abbreviations xiii
PART I Physiology of Glia 1
1 Introduction to Glia 3
1.1 Founders of glial research: from Gabriel Valentin to Karl Ludwig Schleich 3
1.2 Beginning of the modern era 11
1.3 Changing concepts: Glia express molecules of excitation 11
1.4 Glia and neurones in dialogue 12
2 General Overview of Signalling in the Nervous System 13
2.1 Intercellular signalling: Wiring and volume modes of transmission 13
2.2 Intracellular signalling 17
3 Morphology of Glial Cells 21
3.1 Astrocytes 21
3.2 Oligodendrocytes 24
3.3 NG2 expressing glia 26
3.4 Schwann cells 27
3.5 Microglia 28
4 Glial Development 29
4.1 Phylogeny of glia and evolutionary specificity of glial cells in human brain 29
4.2 Macroglial cells 32
4.3 Astroglial cells are brain stem cells 35
4.4 Schwann cell lineage 36
4.5 Microglial cell lineage 37
5 General Physiology of Glial Cells 39
5.1 Membrane potential and ion distribution 39
5.2 Ion channels 39
5.3 Receptors to neurotransmitters and neuromodulators 42
5.4 Glial syncytium gap junctions 58
viii CONTENTS
5.5 dial calcium signalling 61
5.6 Neurotransmitter release from astroglial cells 71
5.7 dial neurotransmitter transporters 76
5.8 dial cells produce and release neuropeptides 79
5.9 dial cell derived growth factors 80
6 Neuronal Glial Interactions 83
6.1 Close apposition of neurones and astroglia: the tripartite synapse 83
6.2 Neuronal glial synapses 85
6.3 Signalling from neurones to astrocytes 86
6.4 Signalling from astrocytes to neurones 89
6.5 Signalling between oligodendrocytes and neurones 90
6.6 Signalling between Schwann cells and peripheral nerves and nerve
endings 90
PART II Glial Cells and Nervous System Function 93
7 Astrocytes 95
7.1 Developmental function producing new neural cells 96
7.2 Developmental function neuronal guidance 97
7.3 Regulation of synaptogenesis and control of synaptic maintenance and
elimination 99
7.4 Structural function creation of the functional microarchitecture of the
brain 101
7.5 Vascular function creation of glial vascular interface (blood brain
barrier) and glia neurone vascular units 102
7.6 Regulation of brain microcirculation 105
7.7 Ion homeostasis in the extracellular space 106
7.8 Regulation of extracellular glutamate concentration 112
7.9 Water homeostasis and regulation of the extracellular space volume 114
7.10 Neuronal metabolic support 116
7.11 Astroglia regulate synaptic transmission 119
7.12 Integration in neuronal glial networks 121
7.13 Astrocytes as cellular substrate of memory and consciousness? 121
8 Oligodendrocytes, Schwann Cells and Myelination 125
8.1 The myelin sheath 127
8.2 Myelination 141
8.3 Myelin and propagation of the action potential 148
PART III Glia and Nervous System Pathology 153
9 General Pathophysiology of Glia 155
9.1 Reactive astrogliosis 155
9.2 Wallerian degeneration 157
9.3 Activation of microglia 160
CONTENTS ix
10 Glia and Diseases of the Nervous System 167
10.1 Alexander s disease 167
10.2 Spreading depression 167
10.3 Stroke and ischaemia 168
10.4 Cytotoxic brain oedema 178
10.5 Neurodegenerative diseases 180
10.6 Neuropathic pain 185
10.7 Demyelinating diseases 186
10.8 Infectious diseases 187
10.9 Peripheral neuropathies 190
10.10 Psychiatric diseases 192
10.11 Gliomas 194
Conclusions 197
Recommended literature 199
Author Index 207
Subject Index 209
|
| adam_txt |
Contents
Preface xi
List of abbreviations xiii
PART I Physiology of Glia 1
1 Introduction to Glia 3
1.1 Founders of glial research: from Gabriel Valentin to Karl Ludwig Schleich 3
1.2 Beginning of the modern era 11
1.3 Changing concepts: Glia express molecules of excitation 11
1.4 Glia and neurones in dialogue 12
2 General Overview of Signalling in the Nervous System 13
2.1 Intercellular signalling: Wiring and volume modes of transmission 13
2.2 Intracellular signalling 17
3 Morphology of Glial Cells 21
3.1 Astrocytes 21
3.2 Oligodendrocytes 24
3.3 NG2 expressing glia 26
3.4 Schwann cells 27
3.5 Microglia 28
4 Glial Development 29
4.1 Phylogeny of glia and evolutionary specificity of glial cells in human brain 29
4.2 Macroglial cells 32
4.3 Astroglial cells are brain stem cells 35
4.4 Schwann cell lineage 36
4.5 Microglial cell lineage 37
5 General Physiology of Glial Cells 39
5.1 Membrane potential and ion distribution 39
5.2 Ion channels 39
5.3 Receptors to neurotransmitters and neuromodulators 42
5.4 Glial syncytium gap junctions 58
viii CONTENTS
5.5 dial calcium signalling 61
5.6 Neurotransmitter release from astroglial cells 71
5.7 dial neurotransmitter transporters 76
5.8 dial cells produce and release neuropeptides 79
5.9 dial cell derived growth factors 80
6 Neuronal Glial Interactions 83
6.1 Close apposition of neurones and astroglia: the tripartite synapse 83
6.2 Neuronal glial synapses 85
6.3 Signalling from neurones to astrocytes 86
6.4 Signalling from astrocytes to neurones 89
6.5 Signalling between oligodendrocytes and neurones 90
6.6 Signalling between Schwann cells and peripheral nerves and nerve
endings 90
PART II Glial Cells and Nervous System Function 93
7 Astrocytes 95
7.1 Developmental function producing new neural cells 96
7.2 Developmental function neuronal guidance 97
7.3 Regulation of synaptogenesis and control of synaptic maintenance and
elimination 99
7.4 Structural function creation of the functional microarchitecture of the
brain 101
7.5 Vascular function creation of glial vascular interface (blood brain
barrier) and glia neurone vascular units 102
7.6 Regulation of brain microcirculation 105
7.7 Ion homeostasis in the extracellular space 106
7.8 Regulation of extracellular glutamate concentration 112
7.9 Water homeostasis and regulation of the extracellular space volume 114
7.10 Neuronal metabolic support 116
7.11 Astroglia regulate synaptic transmission 119
7.12 Integration in neuronal glial networks 121
7.13 Astrocytes as cellular substrate of memory and consciousness? 121
8 Oligodendrocytes, Schwann Cells and Myelination 125
8.1 The myelin sheath 127
8.2 Myelination 141
8.3 Myelin and propagation of the action potential 148
PART III Glia and Nervous System Pathology 153
9 General Pathophysiology of Glia 155
9.1 Reactive astrogliosis 155
9.2 Wallerian degeneration 157
9.3 Activation of microglia 160
CONTENTS ix
10 Glia and Diseases of the Nervous System 167
10.1 Alexander's disease 167
10.2 Spreading depression 167
10.3 Stroke and ischaemia 168
10.4 Cytotoxic brain oedema 178
10.5 Neurodegenerative diseases 180
10.6 Neuropathic pain 185
10.7 Demyelinating diseases 186
10.8 Infectious diseases 187
10.9 Peripheral neuropathies 190
10.10 Psychiatric diseases 192
10.11 Gliomas 194
Conclusions 197
Recommended literature 199
Author Index 207
Subject Index 209 |
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| index_date | 2024-07-02T19:07:25Z |
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| isbn | 9780470015643 9780470517406 |
| language | English |
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| spelling | Verkhratsky, Alexej Verfasser aut Glial neurobiology a textbook Alexei Verkhratsky ; Arthur Butt Chichester [u.a.] Wiley 2007 XIV, 215 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Glia Neuroglia Neurophysiologie Butt, Arthur Verfasser aut HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016172229&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Verkhratsky, Alexej Butt, Arthur Glial neurobiology a textbook Glia Neuroglia Neurophysiologie |
| title | Glial neurobiology a textbook |
| title_auth | Glial neurobiology a textbook |
| title_exact_search | Glial neurobiology a textbook |
| title_exact_search_txtP | Glial neurobiology a textbook |
| title_full | Glial neurobiology a textbook Alexei Verkhratsky ; Arthur Butt |
| title_fullStr | Glial neurobiology a textbook Alexei Verkhratsky ; Arthur Butt |
| title_full_unstemmed | Glial neurobiology a textbook Alexei Verkhratsky ; Arthur Butt |
| title_short | Glial neurobiology |
| title_sort | glial neurobiology a textbook |
| title_sub | a textbook |
| topic | Glia Neuroglia Neurophysiologie |
| topic_facet | Glia Neuroglia Neurophysiologie |
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