The laboratory mouse:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Amsterdam [u.a.]
Elsevier, Acad. Press
2006
|
| Ausgabe: | 1. ed., reprint. |
| Schriftenreihe: | The handbook of experimental animals
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis |
| Beschreibung: | XVI, 600 S. Ill., graph. Darst., Kt. |
| ISBN: | 0123364256 9780123364258 |
Internformat
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| 245 | 1 | 0 | |a The laboratory mouse |c ed. by Hans J. Hedrich ... |
| 250 | |a 1. ed., reprint. | ||
| 264 | 1 | |a Amsterdam [u.a.] |b Elsevier, Acad. Press |c 2006 | |
| 300 | |a XVI, 600 S. |b Ill., graph. Darst., Kt. | ||
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| 650 | 4 | |a Animals, Laboratory | |
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Datensatz im Suchindex
| _version_ | 1804137106315935744 |
|---|---|
| adam_text | Contents
List of Contributors
Foreword
Preface
Parti History, Development and Genetics of the
Mouse as a Laboratory Model
Chapter
Jean-Louis Guénet
Introduction
The phylogenetic relationships of the house mouse
Mouse interspecific hybridization
The house mouse as a laboratory model: a historical perspective
The house mouse and its wild relatives
List of relevant URL for mouse resource centers
Chapter
Introduction
Historical foundations
History of mouse genetics and research with the laboratory mouse
The future
Chapter
Carol
Introduction
Laboratory mouse strains
Importance of standardized nomenclature
Mouse resources and repositories
Information resources
Conclusion
Chapter
V Gailus-Durner, KImai,
ENU mutagenesis
Phenogenetics
Positional cloning: from mutation to gene through mapping
Cytogenetics
Chapter
Information Driven and Random Mutagenesis
Martin Hafner
Choosing the sequence driven mutagenesis approach
How to choose genes for a sequence driven approach?
Conditional gene targeting
Choosing the random mutagenesis approach
Generation of gene trap mouse mutants
Generation of ENU mutants
The forgotten mutants
The
Conclusion
Chapter
Louis-MarieHoudebine
Introduction
Tools used to generate transgenic mice and to express
Examples of transgenic models for human diseases
Conclusions and perspectives
h
I- Johannes
q
*~
Carcinogenicity studies
Mutagenicity studies
Immunotoxicity
Chapter
Introduction
Chapter
Introduction
Organ weights
Adrenal gland
Figures
Ampullary gland
Aorta (Figure
Bone (Os; Figure
Bone marrow (medulla ossium; Figure
Brain (cerebrum, encephalon; Figures
Brown fat (Figure
Bulbourethral gland
Cecum
Colon
Clitoral gland
Coagulating gland
Duodenum
Ear (auris; Figure
Epididymis(Figure9.12)
Esophagus (Figure
Estrous cycle
Eye (oculus; Figures
Gallbladder
Harderian gland (Figure
Heart (cor; Figures
Ileum
Intestine (intestinum; Figures
Jejunum
Joint
Kidney
Lacrimal
Larynx
Leydig cells (Figures
Liver (hepar; Figures
Lung (pulmo; Figures
Lymph nodes (lymphonodi, nodi lymphatici; Figure
Mammary gland
Nasal cavity (cavum
Opdc nerve (nervus opticus; Figure
Oral cavity (cavum
Ovary
Oviduct (oviductus, salpinx
Figures
Pancreas (Figure
Pancreatic islets (insulae pancreaticae; Figure
Parathyroid gland
Penis (Figure
Peripheral nerve
Pharynx
Pineal body
Pituitary gland
Preputial gland
Prostate gland
Rectum
Salivary glands (glandulae
Seminal vesicle
Figures
Skeletal muscle (Figures
Skin (cuds, derma, integumentum commune; Figure
Spinal cord (medulla spinal is; Figure
Spleen (lien; Figure
Stomach
Testis (tesris,
Thymus
Thyroid gland
Tongue (lingua; Figure
Tooth (dens; Figure
Trachea (Figure
Ureter
Urethra (Figure
Urinary bladder
Uterus
Vagina
Vas deferens (ductus deferens; Figure
Zymbal s gland (Figure
Chapter
Introduction
Chapter
Andreas Kispert and
Fertilization and preimplantation development
Implantation
Early
Gastmlation and development of the germ layers
Ршї
Chapter
Introduction
I— Clinical evaluation, tissue collection, and preservation of the skin
Development of the normal skin and adnexa
Normal anatomy of the skin and the hair cycle
Nails
Other specialized glands
Skin and adnexal mutant phenotypes
Chapter
Nikohos
Introduction and background
Anatomical considerations
Histopathological characteristics of the normal mouse heart
Mouse electrocardiography
Functional cardiovascular measurements in the mouse
noninvasive
Experimental models
Pathology of MI in mice
Pathology of myocardial hypertrophy
Congestive heart failure
Murine
Chapter
G
Introduction
Physiological measurements
Conclusion
Chapter
Introduction.,
The digestive system
Metabolism
Chapter
Rikard Holmdahl...........................................................................................
Abstract
Introduction
Induced arthritis models
Spontaneous models of arthritis
Pathological pathway diversity in arthritis
A disease oriented approach based on genetics
Hunianization of animal models
Concluding remark
Chapter
Introduction
Terminology
Blood collection and handling
Basics of
Variables affecting
Pathophysiology and interpretation of results
Suggested reading..
Chapter
Sensory Control
Introduction
Measuring social behaviour
Agonistic behaviour in mice
Sensory mediation of mouse social behaviour
Sensory deprivation studies
Conclusions
Chapter
Yukiko
Stress
The stress system
Cerebral mechanisms in stress
Stress and growth/reproduction
Stress and gastrointestinal function
Stress and immune function
Effect of the
Effect of the inflammatory cytokines on the
Stress and host defense
Conclusions
Chapter
Burghart
Genesis of circadian rhythms
Circadian functions of the mouse
Chapter
Introduction
Mechanisms of cellular aging
Aging in the mouse
Mouse models of aging
Organ systems
Conclusion
Chapter
Commonly Used Inbred Strains and Stocks of
Laboratory Mice
Jerrold
Introduction
Source materials
Strains
Results/discussion
Mouse cancer websites
Conclusions
Chapter
w and Werner Nicklas
2
¡Ü
§
U
Chapter
and Werner Nicklas
Introduction
Husbandry
Preventive care for immunocompromised breeders
Housing conditions
Animal facilities
SPF-units
IVC systems
Static micro-isolators
Isolators (positive pressure)
Isolators (negative pressure)
Quarantine
Therapeutic treatment
Presumptions for genetic manipulation
Identification systems
Refinement
Genetic monitoring
Genetic problems in engineered strains
Computer assisted management of animal facilities
Chapter
Introduction and historical background, evolution of applications
Health standards: definitions and categories
Breeding techniques
Genetic standards and breeding systems
Mating systems and breeding techniques
Chapter
Martina Maria Dorsch................................■................................................... 435
Embryotransfer......................................................................................................
Collection of preimplantation embryos
Cryopreservation and
Setting up a frozen storage
Chapter
Introduction
Significance of infectious agents
Definitions of microbiological status
Sources of infections
Health monitoring programme
Chapter
Introduction
Nutritional requirements
Toxic levels
Contaminants
ITI
Types of diets
Ad libitum feeding versus food restriction
Normal feeding behaviour versus food restriction
Individual housing versus group housing
Isocaloric exchange
Fasting
Mice models in nutrition research
Welfare considerations and enrichment
Chapter
Used for Scientific Experiments
W
Introduction: Historical developments, public and scientific claims
The legal frameworks
Aim and scope of legislation of animal experimentation
The concept of pathocentric animal protection and killing of laboratory animals
Protection of animals differ among die species
The legitimate purposes of animal experimentation
Competence of persons involved in animal experimentation
Humane standards of animal husbandry and care
Control over permitted levels of pain or other forms of distress and the
number of animals used
Permission for animal experimentation
Inspection of facilities and procedures
Alternatives...
Chapter
Igor Mikaelian, Dawnalyn Boggess, Kathleen A.
John P.
Introduction
Biological characterization of a new mutation
Clinical evaluation
Clinical pathology
Gross pathological examination
Fixatives
Euthanasia
Perfusion
Necropsy procedure
Trimming tissues for histology
Skeletal staining of whole mice
Conclusions
Appendix: Examples of commonly used fixatives for mouse histopathology
Chapter
Introduction
Restraining of mice
Effect of handling and restraint on well being of mice
Summary and recommendation
Chapter
General
Principles of administration
Enterai
Chapter
Blood
Urine
Milk
Milking from lactating mice
Semen
Saliva
Lacrimal
Peritoneal fluids
Chapter
Anesthesia...
Analgesia
Euthanasia
Glossary
Index
Colour plates appear between pages
III» 11
|
| adam_txt |
Contents
List of Contributors
Foreword
Preface
Parti History, Development and Genetics of the
Mouse as a Laboratory Model
Chapter
Jean-Louis Guénet
Introduction
The phylogenetic relationships of the house mouse
Mouse interspecific hybridization
The house mouse as a laboratory model: a historical perspective
The house mouse and its wild relatives
List of relevant URL for mouse resource centers
Chapter
Introduction
Historical foundations
History of mouse genetics and research with the laboratory mouse
The future
Chapter
Carol
Introduction
Laboratory mouse strains
Importance of standardized nomenclature
Mouse resources and repositories
Information resources
Conclusion
Chapter
V Gailus-Durner, KImai,
ENU mutagenesis
Phenogenetics
Positional cloning: from mutation to gene through mapping
Cytogenetics
Chapter
Information Driven and Random Mutagenesis
Martin Hafner
Choosing the sequence driven mutagenesis approach
How to choose genes for a sequence driven approach?
Conditional gene targeting
Choosing the random mutagenesis approach
Generation of gene trap mouse mutants
Generation of ENU mutants
The forgotten mutants
The
Conclusion
Chapter
Louis-MarieHoudebine
Introduction
Tools used to generate transgenic mice and to express
Examples of transgenic models for human diseases
Conclusions and perspectives
h
I- Johannes
q
*~
Carcinogenicity studies
Mutagenicity studies
Immunotoxicity
Chapter
Introduction
Chapter
Introduction
Organ weights
Adrenal gland
Figures
Ampullary gland
Aorta (Figure
Bone (Os; Figure
Bone marrow (medulla ossium; Figure
Brain (cerebrum, encephalon; Figures
Brown fat (Figure
Bulbourethral gland
Cecum
Colon
Clitoral gland
Coagulating gland
Duodenum
Ear (auris; Figure
Epididymis(Figure9.12)
Esophagus (Figure
Estrous cycle
Eye (oculus; Figures
Gallbladder
Harderian gland (Figure
Heart (cor; Figures
Ileum
Intestine (intestinum; Figures
Jejunum
Joint
Kidney
Lacrimal
Larynx
Leydig cells (Figures
Liver (hepar; Figures
Lung (pulmo; Figures
Lymph nodes (lymphonodi, nodi lymphatici; Figure
Mammary gland
Nasal cavity (cavum
Opdc nerve (nervus opticus; Figure
Oral cavity (cavum
Ovary
Oviduct (oviductus, salpinx
Figures
Pancreas (Figure
Pancreatic islets (insulae pancreaticae; Figure
Parathyroid gland
Penis (Figure
Peripheral nerve
Pharynx
Pineal body
Pituitary gland
Preputial gland
Prostate gland
Rectum
Salivary glands (glandulae
Seminal vesicle
Figures
Skeletal muscle (Figures
Skin (cuds, derma, integumentum commune; Figure
Spinal cord (medulla spinal is; Figure
Spleen (lien; Figure
Stomach
Testis (tesris,
Thymus
Thyroid gland
Tongue (lingua; Figure
Tooth (dens; Figure
Trachea (Figure
Ureter
Urethra (Figure
Urinary bladder
Uterus
Vagina
Vas deferens (ductus deferens; Figure
Zymbal's gland (Figure
Chapter
Introduction
Chapter
Andreas Kispert and
Fertilization and preimplantation development
Implantation
Early
Gastmlation and development of the germ layers
Ршї
Chapter
Introduction
I— Clinical evaluation, tissue collection, and preservation of the skin
Development of the normal skin and adnexa
Normal anatomy of the skin and the hair cycle
Nails
Other specialized glands
Skin and adnexal mutant phenotypes
Chapter
Nikohos
Introduction and background
Anatomical considerations
Histopathological characteristics of the normal mouse heart
Mouse electrocardiography
Functional cardiovascular measurements in the mouse
noninvasive
Experimental models
Pathology of MI in mice
Pathology of myocardial hypertrophy
Congestive heart failure
Murine
Chapter
G
Introduction
Physiological measurements
Conclusion
Chapter
Introduction.,
The digestive system
Metabolism
Chapter
Rikard Holmdahl.
Abstract
Introduction
Induced arthritis models
Spontaneous models of arthritis
Pathological pathway diversity in arthritis
A disease oriented approach based on genetics
Hunianization of animal models
Concluding remark
Chapter
Introduction
Terminology
Blood collection and handling
Basics of
Variables affecting
Pathophysiology and interpretation of results
Suggested reading.
Chapter
Sensory Control
Introduction
Measuring social behaviour
Agonistic behaviour in mice
Sensory mediation of mouse social behaviour
Sensory deprivation studies
Conclusions
Chapter
Yukiko
Stress
The stress system
Cerebral mechanisms in stress
Stress and growth/reproduction
Stress and gastrointestinal function
Stress and immune function
Effect of the
Effect of the inflammatory cytokines on the
Stress and host defense
Conclusions
Chapter
Burghart
Genesis of circadian rhythms
Circadian functions of the mouse
Chapter
Introduction
Mechanisms of cellular aging
Aging in the mouse
Mouse models of aging
Organ systems
Conclusion
Chapter
Commonly Used Inbred Strains and Stocks of
Laboratory Mice
Jerrold
Introduction
Source materials
Strains
Results/discussion
Mouse cancer websites
Conclusions
Chapter
w and Werner Nicklas
2
¡Ü
§
U
Chapter
and Werner Nicklas
Introduction
Husbandry
Preventive care for immunocompromised breeders
Housing conditions
Animal facilities
SPF-units
IVC systems
Static micro-isolators
Isolators (positive pressure)
Isolators (negative pressure)
Quarantine
Therapeutic treatment
Presumptions for genetic manipulation
Identification systems
Refinement
Genetic monitoring
Genetic problems in engineered strains
Computer assisted management of animal facilities
Chapter
Introduction and historical background, evolution of applications
Health standards: definitions and categories
Breeding techniques
Genetic standards and breeding systems
Mating systems and breeding techniques
Chapter
Martina Maria Dorsch.■. 435
Embryotransfer.
Collection of preimplantation embryos
Cryopreservation and
Setting up a frozen storage
Chapter
Introduction
Significance of infectious agents
Definitions of microbiological status
Sources of infections
Health monitoring programme
Chapter
Introduction
Nutritional requirements
Toxic levels
Contaminants
ITI
Types of diets
Ad libitum feeding versus food restriction
Normal feeding behaviour versus food restriction
Individual housing versus group housing
Isocaloric exchange
Fasting
Mice models in nutrition research
Welfare considerations and enrichment
Chapter
Used for Scientific Experiments
W
Introduction: Historical developments, public and scientific claims
The legal frameworks
Aim and scope of legislation of animal experimentation
The concept of pathocentric animal protection and killing of laboratory animals
Protection of animals differ among die species
The legitimate purposes of animal experimentation
Competence of persons involved in animal experimentation
Humane standards of animal husbandry and care
Control over permitted levels of pain or other forms of distress and the
number of animals used
Permission for animal experimentation
Inspection of facilities and procedures
Alternatives.
Chapter
Igor Mikaelian, Dawnalyn Boggess, Kathleen A.
John P.
Introduction
Biological characterization of a new mutation
Clinical evaluation
Clinical pathology
Gross pathological examination
Fixatives
Euthanasia
Perfusion
Necropsy procedure
Trimming tissues for histology
Skeletal staining of whole mice
Conclusions
Appendix: Examples of commonly used fixatives for mouse histopathology
Chapter
Introduction
Restraining of mice
Effect of handling and restraint on well being of mice
Summary and recommendation
Chapter
General
Principles of administration
Enterai
Chapter
Blood
Urine
Milk
Milking from lactating mice
Semen
Saliva
Lacrimal
Peritoneal fluids
Chapter
Anesthesia.
Analgesia
Euthanasia
Glossary
Index
Colour plates appear between pages
III» 11 |
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| id | DE-604.BV022825578 |
| illustrated | Illustrated |
| index_date | 2024-07-02T18:41:46Z |
| indexdate | 2024-07-09T21:07:01Z |
| institution | BVB |
| isbn | 0123364256 9780123364258 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-016030864 |
| oclc_num | 475596380 |
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| physical | XVI, 600 S. Ill., graph. Darst., Kt. |
| publishDate | 2006 |
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| publisher | Elsevier, Acad. Press |
| record_format | marc |
| series2 | The handbook of experimental animals |
| spelling | The laboratory mouse ed. by Hans J. Hedrich ... 1. ed., reprint. Amsterdam [u.a.] Elsevier, Acad. Press 2006 XVI, 600 S. Ill., graph. Darst., Kt. txt rdacontent n rdamedia nc rdacarrier The handbook of experimental animals Mice as laboratory animals Animals, Laboratory Mice Maus (DE-588)4169148-9 gnd rswk-swf Versuchstiere (DE-588)4078861-1 gnd rswk-swf Versuchstiere (DE-588)4078861-1 s Maus (DE-588)4169148-9 s 1\p DE-604 Hedrich, Hans J. 1944- Sonstige (DE-588)130129364 oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016030864&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis 1\p cgwrk 20201028 DE-101 https://d-nb.info/provenance/plan#cgwrk |
| spellingShingle | The laboratory mouse Mice as laboratory animals Animals, Laboratory Mice Maus (DE-588)4169148-9 gnd Versuchstiere (DE-588)4078861-1 gnd |
| subject_GND | (DE-588)4169148-9 (DE-588)4078861-1 |
| title | The laboratory mouse |
| title_auth | The laboratory mouse |
| title_exact_search | The laboratory mouse |
| title_exact_search_txtP | The laboratory mouse |
| title_full | The laboratory mouse ed. by Hans J. Hedrich ... |
| title_fullStr | The laboratory mouse ed. by Hans J. Hedrich ... |
| title_full_unstemmed | The laboratory mouse ed. by Hans J. Hedrich ... |
| title_short | The laboratory mouse |
| title_sort | the laboratory mouse |
| topic | Mice as laboratory animals Animals, Laboratory Mice Maus (DE-588)4169148-9 gnd Versuchstiere (DE-588)4078861-1 gnd |
| topic_facet | Mice as laboratory animals Animals, Laboratory Mice Maus Versuchstiere |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=016030864&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT hedrichhansj thelaboratorymouse |