Adoptive immunotherapy: methods and protocols
Saved in:
Format: | Book |
---|---|
Language: | English |
Published: |
Totowa, NJ
Humana Press
2005
|
Series: | Methods in molecular medicine
109 |
Subjects: | |
Online Access: | Inhaltsverzeichnis Klappentext |
Physical Description: | XVI, 500 S. Ill., graph. Darst. |
ISBN: | 9781588294067 1588294064 |
Staff View
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650 | 4 | |a Antibodies |x therapeutic use | |
650 | 4 | |a Cancer |x Immunotherapy | |
650 | 4 | |a Cellular therapy | |
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650 | 4 | |a Dendritic Cells | |
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650 | 4 | |a Immunotherapy, Adoptive |x methods | |
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adam_text | Contents
Preface
Contributors
1
of Cancer and Chronic Infection
David O Neill and Nina Bhardwaj
2
Cell-Based Immunotherapy
Gennady Bocharov, Neville
3
Using Biodegradable Microspheres
Ying Waeckerle-Men, Bruno Gander, and Marcus Groettrup
4
Frank
5
Using the CliniMACS System
John D. M. Campbell,
Edith Schwamborn,
and
6 Generation
Using the CliniMACS System
Thomas
Claudia
Georg Bartsch, Lorenz Höltl, and
7
Rienk Off
Delphine
8
Dendritic Cells ior Patient-Specific Immunotherapy
David O Neill and Nina Bhardwaj
9
of Clinical-Grade Dendritic Cells
I.
and
10
Volker
vii
viii
11
Özlem Türeci, Dirk Usener, Sandra Schneider,
and Ugur Sahin
12
and Target Finding for Irrimunotherapy
Petra Weingarten, Petra Lutter, Andreas Wattenberg,
Martin Blueggel, Sonja
Helmut E. Meyer, and Christoph Huels.......................................155
13 Isolation and Expansion
Т
Helga Bernhard, Burkhard
and Christian Peschel
14
With Peptide/MHC Multimers
Norbert Meidenbauer
15
Helmut W. H. G.
and Ton
16
Liquan Gao,
17
Ralf-Holger Voss, Jürgen Kuball,
18
by Means of Cytokine Secretion
Christian Becker
19
Subsets Based on Gene Expression and
History Analysis
Nathalie
20
and Functional Testing of CD4+CD25+ Regulatory T-Cells
Helmut Jonuleit and Edgar
21
and Transplantation
Lucienne Chatenoud
22
Dipankar Das and Mavanur R. Suresh
23
Gustavo Helguera and Manuel L. Penichet
Contents ix
24
Immunoconjugate
Ahmad Safavy and Kevin P. Raisch
25
Liposomes
Cornelia Marty and
26
Atherosclerosis, and Malignant Conditions
lian
27
at a Single Cell Level
Minh Diem
28
William J. Hogan and Hans Joachim
29
Incidence After Bone-Marrow Transplantation
in Experimental Models
Sebastian
30
or Cultured Hematopoietic Stem Cells
in Nonmyeloablated Mice
Nikos Emmanouilidis and Christian P. Larsen
31
Effects After Bone-Marrow Transplantation
Markus
32
for Early GVL Induction and Later Control of GVH Reactions
After Bone-Marrow Transplantation
Attilio Bondanza, Fabio Ciceri,
Index
Over the last decade, major advances in our understanding of the immune system and its mech¬
anisms have led to promising new treatment strategies. In Adoptive Immunotherapy: Methods and
Protocols, leading experts describe in detail their optimal techniques for producing and character¬
izing the ¡mmunologically active cells and effector molecules now gaining wide use in the clinical
treatment of patients. Taking advantage of the latest technologies, the authors present readily
reproducible experimental protocols for the study of dendritic cells,
and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on
the progress of selected approaches in clinical trials. Additional chapters cover the molecular
definition of target antigens, mathematical modeling approaches to ¡mmonotherapy, and the
utilization of regulatory
improvement of adoptive ¡mmunotherapy complete the volume. The protocols followthe successful
Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions,
an introduction outlining the principle behind the technique, lists of the necessary equipment and
reagents, and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and state-of-the-art, Adoptive Immunotherapy: Methods and Protocols offers an
authoritative collection of novel techniquesto study the adoptive transfer of tailored antigen-specific
immune cells and to improve their clinical application.
State-of-the-art methods for adoptive
immunotherapy future directions for adoptive
Novel techniques in the molecular design immunotherapy
and application of antigen-specific
Review of the progress of selected successful results
approaches in clinical trials ° Tricks of the trade and notes on trouble-
Emphasis on preclinical and clinical shooting and avoiding known pitfalls
applications
|
adam_txt |
Contents
Preface
Contributors
1
of Cancer and Chronic Infection
David O'Neill and Nina Bhardwaj
2
Cell-Based Immunotherapy
Gennady Bocharov, Neville
3
Using Biodegradable Microspheres
Ying Waeckerle-Men, Bruno Gander, and Marcus Groettrup
4
Frank
5
Using the CliniMACS System
John D. M. Campbell,
Edith Schwamborn,
and
6 Generation
Using the CliniMACS System
Thomas
Claudia
Georg Bartsch, Lorenz Höltl, and
7
Rienk Off
Delphine
8
Dendritic Cells ior Patient-Specific Immunotherapy
David O'Neill and Nina Bhardwaj
9
of Clinical-Grade Dendritic Cells
I.
and
10
Volker
vii
viii
11
Özlem Türeci, Dirk Usener, Sandra Schneider,
and Ugur Sahin
12
and Target Finding for Irrimunotherapy
Petra Weingarten, Petra Lutter, Andreas Wattenberg,
Martin Blueggel, Sonja
Helmut E. Meyer, and Christoph Huels.155
13 Isolation and Expansion
Т
Helga Bernhard, Burkhard
and Christian Peschel
14
With Peptide/MHC Multimers
Norbert Meidenbauer
15
Helmut W. H. G.
and Ton
16
Liquan Gao,
17
Ralf-Holger Voss, Jürgen Kuball,
18
by Means of Cytokine Secretion
Christian Becker
19
Subsets Based on Gene Expression and
History Analysis
Nathalie
20
and Functional Testing of CD4+CD25+ Regulatory T-Cells
Helmut Jonuleit and Edgar
21
and Transplantation
Lucienne Chatenoud
22
Dipankar Das and Mavanur R. Suresh
23
Gustavo Helguera and Manuel L. Penichet
Contents ix
24
Immunoconjugate
Ahmad Safavy and Kevin P. Raisch
25
Liposomes
Cornelia Marty and
26
Atherosclerosis, and Malignant Conditions
lian
27
at a Single Cell Level
Minh Diem
28
William J. Hogan and Hans Joachim
29
Incidence After Bone-Marrow Transplantation
in Experimental Models
Sebastian
30
or Cultured Hematopoietic Stem Cells
in Nonmyeloablated Mice
Nikos Emmanouilidis and Christian P. Larsen
31
Effects After Bone-Marrow Transplantation
Markus
32
for Early GVL Induction and Later Control of GVH Reactions
After Bone-Marrow Transplantation
Attilio Bondanza, Fabio Ciceri,
Index
Over the last decade, major advances in our understanding of the immune system and its mech¬
anisms have led to promising new treatment strategies. In Adoptive Immunotherapy: Methods and
Protocols, leading experts describe in detail their optimal techniques for producing and character¬
izing the ¡mmunologically active cells and effector molecules now gaining wide use in the clinical
treatment of patients. Taking advantage of the latest technologies, the authors present readily
reproducible experimental protocols for the study of dendritic cells,
and bone marrow transplantation. The emphasis is on preclinicical and clinical applications and on
the progress of selected approaches in clinical trials. Additional chapters cover the molecular
definition of target antigens, mathematical modeling approaches to ¡mmonotherapy, and the
utilization of regulatory
improvement of adoptive ¡mmunotherapy complete the volume. The protocols followthe successful
Methods in Molecular Medicine™ series format, each offering step-by-step laboratory instructions,
an introduction outlining the principle behind the technique, lists of the necessary equipment and
reagents, and tips on troubleshooting and avoiding known pitfalls.
Comprehensive and state-of-the-art, Adoptive Immunotherapy: Methods and Protocols offers an
authoritative collection of novel techniquesto study the adoptive transfer of tailored antigen-specific
immune cells and to improve their clinical application.
State-of-the-art methods for adoptive
immunotherapy future directions for adoptive
Novel techniques in the molecular design immunotherapy
and application of antigen-specific
Review of the progress of selected successful results
approaches in clinical trials ° Tricks of the trade and notes on trouble-
Emphasis on preclinical and clinical shooting and avoiding known pitfalls
applications |
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spelling | Adoptive immunotherapy methods and protocols ed. by Burkhard Ludewig ... Totowa, NJ Humana Press 2005 XVI, 500 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular medicine 109 Cancer - Immunothérapie Cellules immunocompétentes - Emploi en thérapeutique Thérapie cellulaire Antibodies therapeutic use Cancer Immunotherapy Cellular therapy Cytotoxicity, Immunologic Dendritic Cells Immunocompetent cells Therapeutic use Immunotherapy, Adoptive methods Stem Cell Transplantation T-Lymphocytes Immuntherapie (DE-588)4026640-0 gnd rswk-swf Molekulare Medizin (DE-588)4543844-4 gnd rswk-swf Immuntherapie (DE-588)4026640-0 s Molekulare Medizin (DE-588)4543844-4 s b DE-604 Ludewig, Burkhard Sonstige oth Methods in molecular medicine 109 (DE-604)BV011334960 109 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015733439&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015733439&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
spellingShingle | Adoptive immunotherapy methods and protocols Methods in molecular medicine Cancer - Immunothérapie Cellules immunocompétentes - Emploi en thérapeutique Thérapie cellulaire Antibodies therapeutic use Cancer Immunotherapy Cellular therapy Cytotoxicity, Immunologic Dendritic Cells Immunocompetent cells Therapeutic use Immunotherapy, Adoptive methods Stem Cell Transplantation T-Lymphocytes Immuntherapie (DE-588)4026640-0 gnd Molekulare Medizin (DE-588)4543844-4 gnd |
subject_GND | (DE-588)4026640-0 (DE-588)4543844-4 |
title | Adoptive immunotherapy methods and protocols |
title_auth | Adoptive immunotherapy methods and protocols |
title_exact_search | Adoptive immunotherapy methods and protocols |
title_exact_search_txtP | Adoptive immunotherapy methods and protocols |
title_full | Adoptive immunotherapy methods and protocols ed. by Burkhard Ludewig ... |
title_fullStr | Adoptive immunotherapy methods and protocols ed. by Burkhard Ludewig ... |
title_full_unstemmed | Adoptive immunotherapy methods and protocols ed. by Burkhard Ludewig ... |
title_short | Adoptive immunotherapy |
title_sort | adoptive immunotherapy methods and protocols |
title_sub | methods and protocols |
topic | Cancer - Immunothérapie Cellules immunocompétentes - Emploi en thérapeutique Thérapie cellulaire Antibodies therapeutic use Cancer Immunotherapy Cellular therapy Cytotoxicity, Immunologic Dendritic Cells Immunocompetent cells Therapeutic use Immunotherapy, Adoptive methods Stem Cell Transplantation T-Lymphocytes Immuntherapie (DE-588)4026640-0 gnd Molekulare Medizin (DE-588)4543844-4 gnd |
topic_facet | Cancer - Immunothérapie Cellules immunocompétentes - Emploi en thérapeutique Thérapie cellulaire Antibodies therapeutic use Cancer Immunotherapy Cellular therapy Cytotoxicity, Immunologic Dendritic Cells Immunocompetent cells Therapeutic use Immunotherapy, Adoptive methods Stem Cell Transplantation T-Lymphocytes Immuntherapie Molekulare Medizin |
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