Fibrosis research: methods and protocols
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Totowa, NJ
Humana Press
2005
|
| Series: | Methods in molecular medicine
117 |
| Subjects: | |
| Online Access: | Table of contents Inhaltsverzeichnis |
| Physical Description: | XVI, 392 S. Ill., graph. Darst. |
| ISBN: | 158829479X 9781588294791 |
Staff View
MARC
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| 490 | 1 | |a Methods in molecular medicine |v 117 | |
| 650 | 4 | |a Fibrose | |
| 650 | 4 | |a Fibrose - Recherche - Méthodologie | |
| 650 | 4 | |a Fibrosis | |
| 650 | 4 | |a fibrosis |x Research |x Methodology | |
| 650 | 4 | |a Cultured Cells | |
| 650 | 4 | |a Extracellular Matrix |x metabolism | |
| 650 | 4 | |a Models, Animal | |
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Record in the Search Index
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| adam_text | Contents
Preface v
Contributors xiii
Part I. The Clinical Scope of Fibrosis
1 Pulmonary Fibrosis
David A. Zisman, Michael P. Keane, John A. Belperio,
Robert M. Strieter, and Joseph P. Lynch, III 3
2 Renal Fibrosis
H. William Schnaper 45
3 Transforming Growth Factor P: A Key Mediator of Fibrosis
Alain Mauviel 69
Part II. Regulation of Extracellular Matrix Metabolism:
Cultured Cells
4 Isolation and Culture of Skin Fibroblasts
Lame Rittie and Gary J. Fisher 83
5 Isolation and Culture of Hepatic Stellate Cells
Ralf Weiskirchen and Axel M. Gressner 99
6 Isolation and Phenotypic Characterization of Lung Fibroblasts
Carolyn J. Baglole, Sireesha Y. Reddy, Stephen J. Pollock,
Steven E. Feldon, Patricia J. Sime, Terry J. Smith,
and Richard P. Phipps . 115
7 Methods for Measuring Type I Collagen Synthesis In Vitro
David C. Rishikof, Ping Ping Kuang,
Mangalalaxmy Subramanian, and Ronald H. Goldstein 129
8 Methods for Assessing the Molecular Mechanisms Controlling
Gene Regulation
Richard A. Rippe and Branko Stefanovic 141
9 Methods for Measuring TGF p Using Antibodies, Cells, and Mice
Vladimir Jurukovski, Branka Dabovic, Vesna Todorovic,
Yan Chen, and Daniel B. Rifkin 161
Part III. Studying Fibrosis Using Animal Models
10 Morphological Methods for Assessment of Fibrosis
Rakesh K. Kumar 179
xi
xii Contents
11 Methods for Measuring Hydroxyproline and Estimating
In Vivo Rates of Collagen Synthesis and Degradation
Robin J. McAnulty 189
12 Approaches to Evaluation of Fibrogenic Pathways in Surgical
Lung Biopsy Specimens
Cory M. Hogaboam, Kristin f. Carpenter, Holly Evanoff,
and Steven L Kunkel 209
13 Animal Models for Adult Dermal Wound Healing
Mary Birch, Annette Tomlinson, and Mark W. J. Ferguson 223
14 Modeling Liver Fibrosis in Rodents
Christothea Constandinou, Neil Henderson,
and John P. Iredale 237
15 Animal Models of Pulmonary Fibrosis
Mehrnaz Gharaee Kermani, Matthew Ullenbruch,
andSem H. Phan 251
16 Animal Models of Renal Fibrosis
Michael Zeisberg, Mary A. Soubasakos, and Raghu Kalluri 261
1 7 Animal Models of Cardiac Fibrosis
Yao Sun and Karl T. Weber 273
Part IV. Genetic Approaches to Studying Fibrosis
18 Finding Fibrosis Genes: The Lung
Lauranell H. Burch and David A. Schwartz 293
19 Genetic Studies to Identify Hepatic Fibrosis Genes
and SNPs in Human Populations
Christopher Paul Day 315
20 Analysis of Microarray Experiments for Pulmonary Fibrosis
Nilesh B. Dave and Naftali Kaminski 333
21 DNA Microarrays and Data Mining to Study
Hepatic Fibrosis
Bernd Schnabl, Youkyung Hwang Choi, Curt H. Hagedorn,
and Ramon Bataller 359
22 Analysis of Proteins Dominantly Expressed in Hepatic Stellate
Cells of Activated Phenotype: The Molecular Approach
for Liver Fibrosis
Norifumi Kawada 371
Index 381
|
| adam_txt |
Contents
Preface v
Contributors xiii
Part I. The Clinical Scope of Fibrosis
1 Pulmonary Fibrosis
David A. Zisman, Michael P. Keane, John A. Belperio,
Robert M. Strieter, and Joseph P. Lynch, III 3
2 Renal Fibrosis
H. William Schnaper 45
3 Transforming Growth Factor P: A Key Mediator of Fibrosis
Alain Mauviel 69
Part II. Regulation of Extracellular Matrix Metabolism:
Cultured Cells
4 Isolation and Culture of Skin Fibroblasts
Lame Rittie and Gary J. Fisher 83
5 Isolation and Culture of Hepatic Stellate Cells
Ralf Weiskirchen and Axel M. Gressner 99
6 Isolation and Phenotypic Characterization of Lung Fibroblasts
Carolyn J. Baglole, Sireesha Y. Reddy, Stephen J. Pollock,
Steven E. Feldon, Patricia J. Sime, Terry J. Smith,
and Richard P. Phipps . 115
7 Methods for Measuring Type I Collagen Synthesis In Vitro
David C. Rishikof, Ping Ping Kuang,
Mangalalaxmy Subramanian, and Ronald H. Goldstein 129
8 Methods for Assessing the Molecular Mechanisms Controlling
Gene Regulation
Richard A. Rippe and Branko Stefanovic 141
9 Methods for Measuring TGF p Using Antibodies, Cells, and Mice
Vladimir Jurukovski, Branka Dabovic, Vesna Todorovic,
Yan Chen, and Daniel B. Rifkin 161
Part III. Studying Fibrosis Using Animal Models
10 Morphological Methods for Assessment of Fibrosis
Rakesh K. Kumar 179
xi
xii Contents
11 Methods for Measuring Hydroxyproline and Estimating
In Vivo Rates of Collagen Synthesis and Degradation
Robin J. McAnulty 189
12 Approaches to Evaluation of Fibrogenic Pathways in Surgical
Lung Biopsy Specimens
Cory M. Hogaboam, Kristin f. Carpenter, Holly Evanoff,
and Steven L Kunkel 209
13 Animal Models for Adult Dermal Wound Healing
Mary Birch, Annette Tomlinson, and Mark W. J. Ferguson 223
14 Modeling Liver Fibrosis in Rodents
Christothea Constandinou, Neil Henderson,
and John P. Iredale 237
15 Animal Models of Pulmonary Fibrosis
Mehrnaz Gharaee Kermani, Matthew Ullenbruch,
andSem H. Phan 251
16 Animal Models of Renal Fibrosis
Michael Zeisberg, Mary A. Soubasakos, and Raghu Kalluri 261
1 7 Animal Models of Cardiac Fibrosis
Yao Sun and Karl T. Weber 273
Part IV. Genetic Approaches to Studying Fibrosis
18 Finding Fibrosis Genes: The Lung
Lauranell H. Burch and David A. Schwartz 293
19 Genetic Studies to Identify Hepatic Fibrosis Genes
and SNPs in Human Populations
Christopher Paul Day 315
20 Analysis of Microarray Experiments for Pulmonary Fibrosis
Nilesh B. Dave and Naftali Kaminski 333
21 DNA Microarrays and Data Mining to Study
Hepatic Fibrosis
Bernd Schnabl, Youkyung Hwang Choi, Curt H. Hagedorn,
and Ramon Bataller 359
22 Analysis of Proteins Dominantly Expressed in Hepatic Stellate
Cells of Activated Phenotype: The Molecular Approach
for Liver Fibrosis
Norifumi Kawada 371
Index 381 |
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| language | English |
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| spelling | Fibrosis research methods and protocols ed. by John Varga ... Totowa, NJ Humana Press 2005 XVI, 392 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Methods in molecular medicine 117 Fibrose Fibrose - Recherche - Méthodologie Fibrosis fibrosis Research Methodology Cultured Cells Extracellular Matrix metabolism Models, Animal Molekulare Medizin (DE-588)4543844-4 gnd rswk-swf Fibrose (DE-588)4198241-1 gnd rswk-swf Fibrose (DE-588)4198241-1 s Molekulare Medizin (DE-588)4543844-4 s b DE-604 Varga, John Sonstige oth Methods in molecular medicine 117 (DE-604)BV011334960 117 http://www.loc.gov/catdir/toc/ecip059/2005006567.html Table of contents HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015733109&sequence=000009&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Fibrosis research methods and protocols Methods in molecular medicine Fibrose Fibrose - Recherche - Méthodologie Fibrosis fibrosis Research Methodology Cultured Cells Extracellular Matrix metabolism Models, Animal Molekulare Medizin (DE-588)4543844-4 gnd Fibrose (DE-588)4198241-1 gnd |
| subject_GND | (DE-588)4543844-4 (DE-588)4198241-1 |
| title | Fibrosis research methods and protocols |
| title_auth | Fibrosis research methods and protocols |
| title_exact_search | Fibrosis research methods and protocols |
| title_exact_search_txtP | Fibrosis research methods and protocols |
| title_full | Fibrosis research methods and protocols ed. by John Varga ... |
| title_fullStr | Fibrosis research methods and protocols ed. by John Varga ... |
| title_full_unstemmed | Fibrosis research methods and protocols ed. by John Varga ... |
| title_short | Fibrosis research |
| title_sort | fibrosis research methods and protocols |
| title_sub | methods and protocols |
| topic | Fibrose Fibrose - Recherche - Méthodologie Fibrosis fibrosis Research Methodology Cultured Cells Extracellular Matrix metabolism Models, Animal Molekulare Medizin (DE-588)4543844-4 gnd Fibrose (DE-588)4198241-1 gnd |
| topic_facet | Fibrose Fibrose - Recherche - Méthodologie Fibrosis fibrosis Research Methodology Cultured Cells Extracellular Matrix metabolism Models, Animal Molekulare Medizin |
| url | http://www.loc.gov/catdir/toc/ecip059/2005006567.html http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015733109&sequence=000009&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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