The cutaneous lymphoid proliferations: a comprehensive textbook of lymphocytic infiltrates of the skin
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Hoboken, NJ
Wiley-Liss
2007
|
| Subjects: | |
| Online Access: | Inhaltsverzeichnis Klappentext |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | IX, 499 S. zahlr. Ill., graph. Darst. |
| ISBN: | 047169598X 9780471695981 |
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| 245 | 1 | 0 | |a The cutaneous lymphoid proliferations |b a comprehensive textbook of lymphocytic infiltrates of the skin |c Cynthia M. Magro, A. Neil Crowson, Martin C. Mihm |
| 264 | 1 | |a Hoboken, NJ |b Wiley-Liss |c 2007 | |
| 300 | |a IX, 499 S. |b zahlr. Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Lymphoproliferative disorders | |
| 650 | 4 | |a Skin |x Pathology | |
| 650 | 4 | |a Skin |x Tumors | |
| 650 | 4 | |a Lymphomas | |
| 650 | 0 | 7 | |a Hautkrebs |0 (DE-588)4140169-4 |2 gnd |9 rswk-swf |
| 650 | 0 | 7 | |a Lymphoproliferative Krankheit |0 (DE-588)4201162-0 |2 gnd |9 rswk-swf |
| 689 | 0 | 0 | |a Lymphoproliferative Krankheit |0 (DE-588)4201162-0 |D s |
| 689 | 0 | 1 | |a Hautkrebs |0 (DE-588)4140169-4 |D s |
| 689 | 0 | |5 DE-604 | |
| 700 | 1 | |a Magro, Cynthia M. |e Sonstige |4 oth | |
| 700 | 1 | |a Crowson, A. Neil |d 1956- |e Sonstige |0 (DE-588)173504663 |4 oth | |
| 700 | 1 | |a Mihm, Martin C. |d 1934- |e Sonstige |0 (DE-588)141037539 |4 oth | |
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| 856 | 4 | 2 | |m Digitalisierung UB Regensburg |q application/pdf |u http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015651262&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |3 Klappentext |
| 999 | |a oai:aleph.bib-bvb.de:BVB01-015651262 | ||
Record in the Search Index
| _version_ | 1804136520175583232 |
|---|---|
| adam_text | CONTENTS
шжнягаш
1^-^— -r.~> i-:.,^
if,.·
r.-.~......b^^__
■tti_í?T_^!_Styí,
Introduction to the Classification
of Lymphoma
Martin
С
Mihm, Cynthia M.
Magro,
and A. Neil Crowson
Kiel, Lukes-Collins, and Working Formulation
Classifications,
1
WHO, Real, and EORTC Classifications,
2
Summary,
6
References,
7
Appendix: Definitions of Key Terms and
Techniques,
8
Skin-Directed Therapies,
20
References,
23
иишия
The Therapy of Cutaneous
Τ
Cell Lymphoma
14
Pierluigi Porcu and Mark A. Bechtel
Introduction,
14
Diagnostic Work-up and Staging Procedures,
15
Goals of Therapy in Advanced Stage CTCL,
15
Extracorporeal Photopheresis (ECP),
15
Interferons, 16
Retinoids,
16
Immunotoxins,
17
Monoclonal Antibodies,
17
Cytotoxic Chemotherapy,
18
Investigational Therapies,
18
Monoclonal Antibodies,
19
TLR Agonists and Cytokines,
19
Histone Deacetylase Inhibitors (HDACi),
19
Allogeneic Hematopoietic Stem Cell
Transplantation (allo-HSCT),
20
CTCL Therapies,
20
Molecular Techniques
25
Carl Morrison
Introduction,
25
Immunoglobulin Receptor Structure,
26
IgH,
26
TCR-ß, 27
PCR Design for Determination of Clonality,
27
Detection of PCR Products for Clonality,
27
Evaluation of Results,
29
Limitations of Clonality Assessment by PCR,
30
Summary,
31
References,
32
шнишшжзн
Benign Lymphocytic Infiltrates
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
33
Spongiotic and Eczematous Dermatitis,
33
Allergic Contact Dermatitis,
33
Pityriasis
Rosea,
36
Pityriasis Rosea-like
Drug Reaction,
37
Other Spongiotic/Eczematous Tissue
Reactions,
37
Photoallergic Reactions,
37
Other Causes of
Subacute
Eczematous
Dermatitis,
38
Nummular Eczema,
38
Small Plaque
Parapsoriasis,
39
33
VI
CONTENTS
Pruritic Urticarial
Plaques
and Papules of
Pregnancy,
39
Superficial Erythema Annulare Centrifugum,
39
Interface Dermatitis: Cell-Poor Vacuolar Interface
Dermatitis,
40
Erythema
Multiforme,
40
Gianotti-Crosti Syndrome (Popular Acrodermatitis
of Childhood),
42
Acute Grafl-Versus-Host Disease,
42
Morbiliform Viral Exanthem and Morbiliform
Drug Eruption,
44
Collagen Vascular Disease Compatible with
Antibody-Dependent Cellular Immunity and/or
Anti
endothelial Cell Antibodies,
44
Interface Dermatitis: Lichenoid Pattern,
46
Lichen Planus,
46
Lichen Planus-like Eruptions of Hepatobiliary
Disease,
47
Lichen Planus-like Eruptions of Secondary
Syphilis,
48
Lichenoid Drug Reactions,
48
Lichenoid Connective Tissue Disease
Syndromes,
48
Lichenoid ( Chronic ) Grafl-Versus-Host
Disease,
51
Diffuse and Nodular Lymphocytic Dermal
Infiltrates Without Atypia,
52
Polymorphous Light Eruption as the
Prototypie
Type IV Immune Reaction,
52
Other Dermal Permascular Lymphocytic
Infiltrates,
54
Gyrate Erythemas,
54
Diffuse and Nodtilar Lymphocytic Infiltrates
Associated with Autoimmune Disease,
55
Nonscarring Discoid Lupus Erytbematosus/Tumid
Lupus Erythematosus,
55
Morphea,
56
Jessner s Lymphocytic Infiltrate of the Skin,
58
References,
60
Reactive Lymphomatoid Tissue Reactions
Mimicking Cutaneous
Τ
and
В
Cell
Lymphoma
Cynthia M.
Magro
and A. Neil Crowson
Lymphomatoid Drug Eruptions,
64
Molecular Prof
ile
of Lymphomatoid Drag
Eruptions,
66
63
Pathogenetic Basis of Lymphomatoid Drug
Reactions,
67
Reactive Lymphomatoid Lesions Encountered in
Lesions of Collagen Vascular Disease,
68
Lymphomatoid Lupus Erythematosns,
68
Ρ
autogenesis of Lymphomatoid Tissue Response in
Collagen Vascular Disease,
69
Lupus Erythematosus
Profundus, 69
Viral-Associated Lymphomatoid Dermatitis,
70
Lymphocytoma
Cutis,
70
Primary Cutaneous Plasmacytosis,
71
Conclusion,
72
Case Vignettes,
73
References,
89
Precursor Lesions of Cutaneous
Τ
Cell Lymphoma
93
Cynthia M.
Magro, Joan
Guitart and A. Neil
Crowson
Cutaneous
Τ
Cell Lymphoid Dyscrasia,
93
Large Plaque
Parapsoriasis,
94
Hypopigmented Epitheliotropic
T
Cell
Dyscrasia/Hypopigmented Large Plaque
Parapsoriasis
as a Precursor Lesion to
Hypopigmented Mycosis Fungoides,
96
Pigmented
Purpurie
Dermatosis (PPD),
97
Pityriasis
Lichenoides Chronica,
100
Syringolymphoid Hyperplasia with Alopecia,
103
Idiopathic Follicular Mucinosis/Alopecia
Mucinosa,
104
Atypical Lymphocytic
Lobular Panniculitís,
106
Case Vignettes,
109
Additional Molecular and Cytogenetic
Studies,
126
References,
138
Marginal Zone Lymphoma and Other
Low-Grade
В
Cell Lymphoproliferative
Disorders of the Skin
141
Cynthia M.
Magro
and A. Neil Crowson
Marginal Zone Lymphoma,
141
Castleman s Disease,
148
Primary Cutaneous Plasmacytoma,
149
Case Vignettes,
151
References,
170
CONTENTS
VII
шжнж
Primary Cutaneous Follicle Center
Cell Lymphoma
173
Cynthia M.
Magro
and A. Neil Crowson
Case Vignettes,
178
Additional Molecular and Cytogenetic Study,
190
References,
191
Primary Cutaneous Diffuse Large B-Cell
Lymphoma and Precursor Lymphoblastic
Lymphoma
192
Cynthia M.
Magro
and A. Neil Crowson
Primary Cutaneous Diffuse Large B-Cell
Lymphoma,
192
Cutaneous Precursor
В
Cell Lymphoblastic
Lymphoma/Lymphoblastic Leukemia (Precursor
В
Cell Acute Lymphoblastic Leukemia,
198
Case Vignettes,
203
Additional Molecular and Cytogenetic
Studies,
213
References,
216
219
Intravascular
Lymphoma
Cynthia M.
Magro
and A. Neil Crowson
Case Vignette,
222
References,
224
Chronic Lymphocytic Leukemia of
В
Cell and
Τ
Cell Phenotype (T Cell Prolymphocytic
Leukemia)
226
Cynthia M.
Magro
and A. Neil Crowson
В
Cell Chronic Lymphocytic Leukemia,
226
Τ
Cell Prolymphocytic Leukemia,
228
Case Vignettes,
231
Additional Molecular and Cytogenetic
Studies,
244
References,
246
OMFfWJI.TWBEVe
Cutaneous Mantle Cell Lymphoma
Cynthia M.
Magro
and A. Neil Crowson
Case Vignettes,
252
Additional Molecular and Cytogenetic
Studies,
256
References,
257
248
ШЖИЖЗ
Primary Cutaneous
γδ Τ
Cell Lymphoma
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
259
Case Vignette,
264
References,
266
259
267
Mycosis Fungoides
Cynthia M.
Magro,
Martin
С
Mihm,
and A. Neil Crowson
Definition,
267
Historical Perspective,
267
Demographics,
267
Clinical Presentation,
267
Patch Stage,
268
Plaque Stage,
270
Tumor Stage,
270
Extracutaneous Dissemination,
271
Clinical Variants,
271
Papuloerythroderma,
271
Mycosis Fungoides in Childhood,
271
Adnexotropic Mycosis Fungoides,
272
Woringer-Kolopp Disease (Pagetoid
Reticulosis),
272
Granulomatous Slack Skin/Granulomatous Mycosis
Fungoides,
273
Sezary Syndrome,
273
Extracutaneous Involvement in Mycosis
Fungoides,
285
Phenotypic Profile,
286
Molecular Profile,
288
Cytogenetics,
288
Pathogenesis,
288
Case Vignettes,
290
Additional Molecular and Cytogenetic
Studies,
292
References,
297
Primary Cutaneous Pleomorphic Small/Medium
Sized
Т
-Celi
Lymphoma And Peripheral T-Cell
Lymphoma, Unspecified, Presenting in the SKiN
(CDBO-Negative Large Cell
Τ
Cell
Lymphoma)
300
Cynthia M.
Magro
and A. Neil Crowson
Case Vignettes,
306
VIII
CONTENTS
Additional Molecular and Cytogenetic Study,
315
References,
316
Adult
Τ
Cell Leukemia/Lymphoma
318
Cynthia M.
Magro
Case Vignettes,
322
References,
327
Angioimmunoblastic Lymphadenopathy
(AlLDVAngioimmunobiasticT Cell Lymphoma
329
Cynthia M.
Magro
and A. Neil Crowson
Case Vignettes,
334
References,
340
CD8
Τ
Cell Lymphoproliferative Disease of the
Skin
343
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
343
Primary Cutaneous CD8 Lymphoma,
343
CD8 Variant ofLymphomatoid Papulosis and
Other Related CDSO-Positive
Τ
Cell
Lymphoproliferative Disorders ofCD8
Subtype,
346
CDS Prolymphocytic
Leiücemia, 347
COS Pseudolymphoma Related to Underlying
HIV
Disease,
348
CD8 Cytotoxic Pseudolymphoma Related to Drug
Therapy,
348
Case Vignettes,
349
References,
364
Subcutaneous Panniculitis-Like
Τ
Cell
Lymphoma
366
Cynthia M.
Magro
and A. Neil Crowson
Case Vignettes,
372
References,
379
Epstein-Ban1 Virus-Associated
Lymphoproliferative Disease
381
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
381
Hydrou
Vacciniforme-Like
EBV-Åssocmted T
Cell
Lfntphoprotiferative
Dismseßaosquilo
Bite
Hypersensttwity,
382
Epstein-Barr Virus-Associated
В
Cell
Lymphoproliferative Disease in the Setting of
Iatrogenic Immune Dysregulation,
384
Case Vignettes,
390
References,
395
Nasal and Related Extranodal Natural
Killer Cell/T Cell Lymphomas
399
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
399
Biology of NK and NK-like
Τ
Cells,
401
NK/T-Cell Lymphoma,
402
Nasal NK/T-Cell Lymphoma,
402
Nasal Type NK/T Cell Lymphoma,
403
Aggressive NK
Cell Lymphoma,
403
Role of Epstein-Barr Virus in the Evolution of
NK/T Cell Lymphomas,
406
Blastic/Blastoid NK Cell Lymphoma/Agranular
CDA-positive
CDSõ-positive
Hematodermic
Neoplasm,
406
Panniculitis-like
Τ
Cell Lymphoma Showing CD56
Positivity,
406
Chronic Granular Lymphocytosis/Large Granular
Cell Leukemia,
407
Natural Killer-like
Τ
Cell Lymphoma of the CD4
Subset: A Rare Variant of Natural Killer Cell
Lymphoma to Be Distinguished from the
Hematodermic Neoplasm,
408
Case Vignettes,
410
References,
425
Lymphomatoid Granulomatosis (LYG)
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
429
Case Vignette,
434
References,
437
429
сшншжжшнзнвш
CDSO-Positive Lymphoproliferative Disorders
Including Lymphomatoid Papulosis, Borderline
CDSO-Positive LymphoproHferative Disease,
Anaplastic Large Cell Lymphoma, and T-Cell-Rich
CDSO-Positive Large
В
Cell Lymphoma
439
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
439
Lyrnphomatoid Papulosis,
440
CD8 Lymphomatoid Papulosis,
444
CONTENTS
І ІХ
Borderline CDSO-Positwe Lymphoproliferatwe
Disorders (Type
С
LYP) (Case
Vignette
9), 445
„ľ t
„
,
..
,
.
°
Primary Cutaneous
Hodgkin Lymphoma
475
Cutaneous Anaplashc Large Cell Lymphoma,
445
Cynthia M.
Magro
COnO-Positive Large
В
Cell Lymphoma,
450
Subtypes of
Hodgkin Lymphoma,
477
Case Vignettes,
452
Classic
Hodgkin
Lymphoma,
477
Additional Molecular and Cytogenetic Lymphocyte-Predominant
Hodgkin
lymphoma, A77
Studies,
468 „ „. ., .„„
Case Vignette,
480
References,
471 ,,,... ,,, , , , ,-, ,
Additional Molecular and Cytogenetic
Studies,
484
References,
486
Index,
489
A COMPLETE REFERENCE TO THE LATEST UNDERSTANDING
OF LYMPHOCYTIC INFILTRATES
Г
he Cutaneous I/ymp ho id Proliferations provides
a complote,
authoritative treatment of the clinical
features, phenotypes. pathogenesis, histopathol-
ogy, diagnosis., and treatment of lymphocytic infiltrates
of the skin. Incorporating the latest findings from the
fields of light microscopy; immunohistochemistry, and
flow cytometry, the. book brings readers up to date, on
the most current thinking in the field. Those readers
familiar with the authors^ critically acclaimed The
Melanocytic, Proliferations will find a similar structure
and the
stime
attention to detail and quality in this
latest reference.
>
The book starts off with a clinical atlas and introduction to
the ontogeny and biology of the lymphoid system. Next,
lhe
authors explore novel molecular approaches to the diagnosis
of cutaneous lymphoid proliferations and benign lympho-
cytic infiltrates. The remaining chapters concentrate on
major inflammatory skin diseases and lymphoproliferative
disorders, including chronic lymphocytic leukemia, lupus,
adult
T
cell leukemia, and primary cutaneous
Hodgkiiľs
disease.
As a reference to lymphocytic infiltrates, this book is unsur¬
passed. Novice and experienced practitioners alike will gain
important insights into the field, including:
•
The role of the immune system in the pathogenesis
of cutaneous disease
•
Relationships between therapeutic drugs and
cutaneous eruptions
•
Important drug reactions
Hundreds of full-color, high-quality clinical and
histologie
photographs help readers visualize, the various infiltrates
and their treatments. Having this reference on hand
is essential for all dermatologists, dermatopathologiste,
oncologists, and general pathologists who need a synthesis
of the current thinking in the field.
CYNTHIA M.
MAGRO, M.D.,
is Profes¬
sor of Pathology and Director of Derma-
topathology at Weill Medical College of
Cornell University in New York City. She
has published extensively in the areas of
inflammatory skin disease, including col¬
lagen vascular disease, vasculitis, cutane-
oiis manifestations of systemic disease, and
unique drug hyperseiisitivity reactions. A
significant focus of her work has been lyruphocytic infiltrates,
including unique forms of drug reactions such as the interstitial
granulomatous drug reaction and drug-associated reversible
T
cell dyscrasia; prelymphomatous cutaneous lymphoid dyscra-
sias including atypical lymphocytic
lobular panniculitis
pityria¬
sis
Hchenoides chronica and
pigmented
purpurie
dermatosis;
and malignant
T
and
В
cell lymphoinas. She has extended her
work in immune mechanisms of skin disease and applied it to
areas of lung transplantation and pulmonary fibrosis,
A. NEIL GROWSON,
MD.,
is Clinical
Professor of Dermatology, Pathology, and
Surgery, and Director of Dermatopathol-
ogy at the University of Oklahoma and
Regional Medical I .laboratory in Tulsa,
Oklahoma. His current research interests
focus on mechanisms of neoplastic and
inflammatory skin disease.
MARTIN
С.
MIHM, Jb., M.D.,
is Clinical
Professor of Pathology and Dermatology
at Harvard Medical School, Massachu¬
setts General Hospital. He is interna¬
tionally recognized for his expertise in
the pathology, diagnosis, and manage¬
ment (xf
pigmented
lesions, lymphoid
disorders, and vascular tumors. He ha»
worked extensively to understand the
host response to melanoma and other tumors. He has served
as
codirector
of the WHO Melanoma Program in addition to
Ins many obligations in translational and clinical research in.
cutaneous
inflammation,
tumor vaccination, and pathogenesis
of vascular lesions in children.
|
| adam_txt |
CONTENTS
шжнягаш
1^-^— '-r.~> "i-:.,^
if,.·
r.-.~.b^^_
■tti_í?T_^!_Styí,
Introduction to the Classification
of Lymphoma
Martin
С
Mihm, Cynthia M.
Magro,
and A. Neil Crowson
Kiel, Lukes-Collins, and Working Formulation
Classifications,
1
WHO, Real, and EORTC Classifications,
2
Summary,
6
References,
7
Appendix: Definitions of Key Terms and
Techniques,
8
Skin-Directed Therapies,
20
References,
23
иишия
The Therapy of Cutaneous
Τ
Cell Lymphoma
14
Pierluigi Porcu and Mark A. Bechtel
Introduction,
14
Diagnostic Work-up and Staging Procedures,
15
Goals of Therapy in Advanced Stage CTCL,
15
Extracorporeal Photopheresis (ECP),
15
Interferons, 16
Retinoids,
16
Immunotoxins,
17
Monoclonal Antibodies,
17
Cytotoxic Chemotherapy,
18
Investigational Therapies,
18
Monoclonal Antibodies,
19
TLR Agonists and Cytokines,
19
Histone Deacetylase Inhibitors (HDACi),
19
Allogeneic Hematopoietic Stem Cell
Transplantation (allo-HSCT),
20
CTCL Therapies,
20
Molecular Techniques
25
Carl Morrison
Introduction,
25
Immunoglobulin Receptor Structure,
26
IgH,
26
TCR-ß, 27
PCR Design for Determination of Clonality,
27
Detection of PCR Products for Clonality,
27
Evaluation of Results,
29
Limitations of Clonality Assessment by PCR,
30
Summary,
31
References,
32
шнишшжзн
Benign Lymphocytic Infiltrates
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
33
Spongiotic and Eczematous Dermatitis,
33
Allergic Contact Dermatitis,
33
Pityriasis
Rosea,
36
Pityriasis Rosea-like
Drug Reaction,
37
Other Spongiotic/Eczematous Tissue
Reactions,
37
Photoallergic Reactions,
37
Other Causes of
Subacute
Eczematous
Dermatitis,
38
Nummular Eczema,
38
Small Plaque
Parapsoriasis,
39
33
VI
CONTENTS
Pruritic Urticarial
Plaques
and Papules of
Pregnancy,
39
Superficial Erythema Annulare Centrifugum,
39
Interface Dermatitis: Cell-Poor Vacuolar Interface
Dermatitis,
40
Erythema
Multiforme,
40
Gianotti-Crosti Syndrome (Popular Acrodermatitis
of Childhood),
42
Acute Grafl-Versus-Host Disease,
42
Morbiliform Viral Exanthem and Morbiliform
Drug Eruption,
44
Collagen Vascular Disease Compatible with
Antibody-Dependent Cellular Immunity and/or
Anti
endothelial Cell Antibodies,
44
Interface Dermatitis: Lichenoid Pattern,
46
Lichen Planus,
46
Lichen Planus-like Eruptions of Hepatobiliary
Disease,
47
Lichen Planus-like Eruptions of Secondary
Syphilis,
48
Lichenoid Drug Reactions,
48
Lichenoid Connective Tissue Disease
Syndromes,
48
Lichenoid ("Chronic") Grafl-Versus-Host
Disease,
51
Diffuse and Nodular Lymphocytic Dermal
Infiltrates Without Atypia,
52
Polymorphous Light Eruption as the
Prototypie
Type IV Immune Reaction,
52
Other Dermal Permascular Lymphocytic
Infiltrates,
54
Gyrate Erythemas,
54
Diffuse and Nodtilar Lymphocytic Infiltrates
Associated with Autoimmune Disease,
55
Nonscarring Discoid Lupus Erytbematosus/Tumid
Lupus Erythematosus,
55
Morphea,
56
Jessner's Lymphocytic Infiltrate of the Skin,
58
References,
60
Reactive Lymphomatoid Tissue Reactions
Mimicking Cutaneous
Τ
and
В
Cell
Lymphoma
Cynthia M.
Magro
and A. Neil Crowson
Lymphomatoid Drug Eruptions,
64
Molecular Prof
ile
of Lymphomatoid Drag
Eruptions,
66
63
Pathogenetic Basis of Lymphomatoid Drug
Reactions,
67
Reactive Lymphomatoid Lesions Encountered in
Lesions of Collagen Vascular Disease,
68
Lymphomatoid Lupus Erythematosns,
68
Ρ
autogenesis of Lymphomatoid Tissue Response in
Collagen Vascular Disease,
69
Lupus Erythematosus
Profundus, 69
Viral-Associated Lymphomatoid Dermatitis,
70
Lymphocytoma
Cutis,
70
Primary Cutaneous Plasmacytosis,
71
Conclusion,
72
Case Vignettes,
73
References,
89
Precursor Lesions of Cutaneous
Τ
Cell Lymphoma
93
Cynthia M.
Magro, Joan
Guitart and A. Neil
Crowson
Cutaneous
Τ
Cell Lymphoid Dyscrasia,
93
Large Plaque
Parapsoriasis,
94
Hypopigmented Epitheliotropic
T
Cell
Dyscrasia/Hypopigmented Large Plaque
Parapsoriasis
as a Precursor Lesion to
Hypopigmented Mycosis Fungoides,
96
Pigmented
Purpurie
Dermatosis (PPD),
97
Pityriasis
Lichenoides Chronica,
100
Syringolymphoid Hyperplasia with Alopecia,
103
Idiopathic Follicular Mucinosis/Alopecia
Mucinosa,
104
Atypical Lymphocytic
Lobular Panniculitís,
106
Case Vignettes,
109
Additional Molecular and Cytogenetic
Studies,
126
References,
138
Marginal Zone Lymphoma and Other
Low-Grade
В
Cell Lymphoproliferative
Disorders of the Skin
141
Cynthia M.
Magro
and A. Neil Crowson
Marginal Zone Lymphoma,
141
Castleman's Disease,
148
Primary Cutaneous Plasmacytoma,
149
Case Vignettes,
151
References,
170
CONTENTS
VII
шжнж
Primary Cutaneous Follicle Center
Cell Lymphoma
173
Cynthia M.
Magro
and A. Neil Crowson
Case Vignettes,
178
Additional Molecular and Cytogenetic Study,
190
References,
191
Primary Cutaneous Diffuse Large B-Cell
Lymphoma and Precursor Lymphoblastic
Lymphoma
192
Cynthia M.
Magro
and A. Neil Crowson
Primary Cutaneous Diffuse Large B-Cell
Lymphoma,
192
Cutaneous Precursor
В
Cell Lymphoblastic
Lymphoma/Lymphoblastic Leukemia (Precursor
В
Cell Acute Lymphoblastic Leukemia,
198
Case Vignettes,
203
Additional Molecular and Cytogenetic
Studies,
213
References,
216
219
Intravascular
Lymphoma
Cynthia M.
Magro
and A. Neil Crowson
Case Vignette,
222
References,
224
Chronic Lymphocytic Leukemia of
В
Cell and
Τ
Cell Phenotype (T Cell Prolymphocytic
Leukemia)
226
Cynthia M.
Magro
and A. Neil Crowson
В
Cell Chronic Lymphocytic Leukemia,
226
Τ
Cell Prolymphocytic Leukemia,
228
Case Vignettes,
231
Additional Molecular and Cytogenetic
Studies,
244
References,
246
OMFfWJI.TWBEVe
Cutaneous Mantle Cell Lymphoma
Cynthia M.
Magro
and A. Neil Crowson
Case Vignettes,
252
Additional Molecular and Cytogenetic
Studies,
256
References,
257
248
ШЖИЖЗ
Primary Cutaneous
γδ Τ
Cell Lymphoma
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
259
Case Vignette,
264
References,
266
259
267
Mycosis Fungoides
Cynthia M.
Magro,
Martin
С
Mihm,
and A. Neil Crowson
Definition,
267
Historical Perspective,
267
Demographics,
267
Clinical Presentation,
267
Patch Stage,
268
Plaque Stage,
270
Tumor Stage,
270
Extracutaneous Dissemination,
271
Clinical Variants,
271
Papuloerythroderma,
271
Mycosis Fungoides in Childhood,
271
Adnexotropic Mycosis Fungoides,
272
Woringer-Kolopp Disease (Pagetoid
Reticulosis),
272
Granulomatous Slack Skin/Granulomatous Mycosis
Fungoides,
273
Sezary Syndrome,
273
Extracutaneous Involvement in Mycosis
Fungoides,
285
Phenotypic Profile,
286
Molecular Profile,
288
Cytogenetics,
288
Pathogenesis,
288
Case Vignettes,
290
Additional Molecular and Cytogenetic
Studies,
292
References,
297
Primary Cutaneous Pleomorphic Small/Medium
Sized
Т
-Celi
Lymphoma And Peripheral T-Cell
Lymphoma, Unspecified, Presenting in the SKiN
(CDBO-Negative Large Cell
Τ
Cell
Lymphoma)
300
Cynthia M.
Magro
and A. Neil Crowson
Case Vignettes,
306
VIII
CONTENTS
Additional Molecular and Cytogenetic Study,
315
References,
316
Adult
Τ
Cell Leukemia/Lymphoma
318
Cynthia M.
Magro
Case Vignettes,
322
References,
327
Angioimmunoblastic Lymphadenopathy
(AlLDVAngioimmunobiasticT Cell Lymphoma
329
Cynthia M.
Magro
and A. Neil Crowson
Case Vignettes,
334
References,
340
CD8
Τ
Cell Lymphoproliferative Disease of the
Skin
343
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
343
Primary Cutaneous CD8 Lymphoma,
343
CD8 Variant ofLymphomatoid Papulosis and
Other Related CDSO-Positive
Τ
Cell
Lymphoproliferative Disorders ofCD8
Subtype,
346
CDS Prolymphocytic
Leiücemia, 347
COS Pseudolymphoma Related to Underlying
HIV
Disease,
348
CD8 Cytotoxic Pseudolymphoma Related to Drug
Therapy,
348
Case Vignettes,
349
References,
364
Subcutaneous Panniculitis-Like
Τ
Cell
Lymphoma
366
Cynthia M.
Magro
and A. Neil Crowson
Case Vignettes,
372
References,
379
Epstein-Ban1 Virus-Associated
Lymphoproliferative Disease
381
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
381
Hydrou
Vacciniforme-Like
EBV-Åssocmted T
Cell
Lfntphoprotiferative
Dismseßaosquilo
Bite
Hypersensttwity,
382
Epstein-Barr Virus-Associated
В
Cell
Lymphoproliferative Disease in the Setting of
Iatrogenic Immune Dysregulation,
384
Case Vignettes,
390
References,
395
Nasal and Related Extranodal Natural
Killer Cell/T Cell Lymphomas
399
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
399
Biology of NK and NK-like
Τ
Cells,
401
NK/T-Cell Lymphoma,
402
Nasal NK/T-Cell Lymphoma,
402
Nasal Type NK/T Cell Lymphoma,
403
Aggressive NK
Cell Lymphoma,
403
Role of Epstein-Barr Virus in the Evolution of
NK/T Cell Lymphomas,
406
Blastic/Blastoid NK Cell Lymphoma/Agranular
CDA-positive
CDSõ-positive
Hematodermic
Neoplasm,
406
Panniculitis-like
Τ
Cell Lymphoma Showing CD56
Positivity,
406
Chronic Granular Lymphocytosis/Large Granular
Cell Leukemia,
407
Natural Killer-like
Τ
Cell Lymphoma of the CD4
Subset: A Rare Variant of Natural Killer Cell
Lymphoma to Be Distinguished from the
Hematodermic Neoplasm,
408
Case Vignettes,
410
References,
425
Lymphomatoid Granulomatosis (LYG)
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
429
Case Vignette,
434
References,
437
429
сшншжжшнзнвш
CDSO-Positive Lymphoproliferative Disorders
Including Lymphomatoid Papulosis, Borderline
CDSO-Positive LymphoproHferative Disease,
Anaplastic Large Cell Lymphoma, and T-Cell-Rich
CDSO-Positive Large
В
Cell Lymphoma
439
Cynthia M.
Magro
and A. Neil Crowson
Introduction,
439
Lyrnphomatoid Papulosis,
440
CD8 Lymphomatoid Papulosis,
444
CONTENTS
І ІХ
Borderline CDSO-Positwe Lymphoproliferatwe
Disorders (Type
С
LYP) (Case
Vignette
9), 445
„ľ t
„
,
.
,
.
°
Primary Cutaneous
Hodgkin Lymphoma
475
Cutaneous Anaplashc Large Cell Lymphoma,
445
Cynthia M.
Magro
COnO-Positive Large
В
Cell Lymphoma,
450
Subtypes of
Hodgkin Lymphoma,
477
Case Vignettes,
452
Classic
Hodgkin
Lymphoma,
477
Additional Molecular and Cytogenetic Lymphocyte-Predominant
Hodgkin
lymphoma, A77
Studies,
468 „ „. ., .„„
Case Vignette,
480
References,
471 ,,,. ,,, , , , ,-, ,
Additional Molecular and Cytogenetic
Studies,
484
References,
486
Index,
489
A COMPLETE REFERENCE TO THE LATEST UNDERSTANDING
OF LYMPHOCYTIC INFILTRATES
Г
he Cutaneous I/ymp ho id Proliferations provides
a complote,
authoritative treatment of the clinical
features, phenotypes. pathogenesis, histopathol-
ogy, diagnosis., and treatment of lymphocytic infiltrates
of the skin. Incorporating the latest findings from the
fields of light microscopy; immunohistochemistry, and
flow cytometry, the. book brings readers up to date, on
the most current thinking in the field. Those readers
familiar with the authors^ critically acclaimed The
Melanocytic, Proliferations will find a similar structure
and the
stime
attention to detail and quality in this
latest reference.
>
The book starts off with a clinical atlas and introduction to
the ontogeny and biology of the lymphoid system. Next,
lhe
authors explore novel molecular approaches to the diagnosis
of cutaneous lymphoid proliferations and benign lympho-
cytic infiltrates. The remaining chapters concentrate on
major inflammatory skin diseases and lymphoproliferative
disorders, including chronic lymphocytic leukemia, lupus,
adult
T
cell leukemia, and primary cutaneous
Hodgkiiľs
disease.
As a reference to lymphocytic infiltrates, this book is unsur¬
passed. Novice and experienced practitioners alike will gain
important insights into the field, including:
•
The role of the immune system in the pathogenesis
of cutaneous disease
•
Relationships between therapeutic drugs and
cutaneous eruptions
•
Important drug reactions
Hundreds of full-color, high-quality clinical and
histologie
photographs help readers visualize, the various infiltrates
and their treatments. Having this reference on hand
is essential for all dermatologists, dermatopathologiste,
oncologists, and general pathologists who need a synthesis
of the current thinking in the field.
CYNTHIA M.
MAGRO, M.D.,
is Profes¬
sor of Pathology and Director of Derma-
topathology at Weill Medical College of
Cornell University in New York City. She
has published extensively in the areas of
inflammatory skin disease, including col¬
lagen vascular disease, vasculitis, cutane-
oiis manifestations of systemic disease, and
unique drug hyperseiisitivity reactions. A
significant focus of her work has been lyruphocytic infiltrates,
including unique forms of drug reactions such as the interstitial
granulomatous drug reaction and drug-associated reversible
T
cell dyscrasia; prelymphomatous cutaneous lymphoid dyscra-
sias including atypical lymphocytic
lobular panniculitis
pityria¬
sis
Hchenoides chronica and
pigmented
purpurie
dermatosis;
and malignant
T
and
В
cell lymphoinas. She has extended her
work in immune mechanisms of skin disease and applied it to
areas of lung transplantation and pulmonary fibrosis,
A. NEIL GROWSON,
MD.,
is Clinical
Professor of Dermatology, Pathology, and
Surgery, and Director of Dermatopathol-
ogy at the University of Oklahoma and
Regional Medical I .laboratory in Tulsa,
Oklahoma. His current research interests
focus on mechanisms of neoplastic and
inflammatory skin disease.
MARTIN
С.
MIHM, Jb., M.D.,
is Clinical
Professor of Pathology and Dermatology
at Harvard Medical School, Massachu¬
setts General Hospital. He is interna¬
tionally recognized for his expertise in
the pathology, diagnosis, and manage¬
ment (xf
pigmented
lesions, lymphoid
disorders, and vascular tumors. He ha»
worked extensively to understand the
host response to melanoma and other tumors. He has served
as
codirector
of the WHO Melanoma Program in addition to
Ins many obligations in translational and clinical research in.
cutaneous
inflammation,
tumor vaccination, and pathogenesis
of vascular lesions in children. |
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| id | DE-604.BV022443250 |
| illustrated | Illustrated |
| index_date | 2024-07-02T17:33:25Z |
| indexdate | 2024-07-09T20:57:42Z |
| institution | BVB |
| isbn | 047169598X 9780471695981 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-015651262 |
| oclc_num | 64771112 |
| open_access_boolean | |
| owner | DE-29 DE-355 DE-BY-UBR |
| owner_facet | DE-29 DE-355 DE-BY-UBR |
| physical | IX, 499 S. zahlr. Ill., graph. Darst. |
| publishDate | 2007 |
| publishDateSearch | 2007 |
| publishDateSort | 2007 |
| publisher | Wiley-Liss |
| record_format | marc |
| spelling | The cutaneous lymphoid proliferations a comprehensive textbook of lymphocytic infiltrates of the skin Cynthia M. Magro, A. Neil Crowson, Martin C. Mihm Hoboken, NJ Wiley-Liss 2007 IX, 499 S. zahlr. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index Lymphoproliferative disorders Skin Pathology Skin Tumors Lymphomas Hautkrebs (DE-588)4140169-4 gnd rswk-swf Lymphoproliferative Krankheit (DE-588)4201162-0 gnd rswk-swf Lymphoproliferative Krankheit (DE-588)4201162-0 s Hautkrebs (DE-588)4140169-4 s DE-604 Magro, Cynthia M. Sonstige oth Crowson, A. Neil 1956- Sonstige (DE-588)173504663 oth Mihm, Martin C. 1934- Sonstige (DE-588)141037539 oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015651262&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015651262&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | The cutaneous lymphoid proliferations a comprehensive textbook of lymphocytic infiltrates of the skin Lymphoproliferative disorders Skin Pathology Skin Tumors Lymphomas Hautkrebs (DE-588)4140169-4 gnd Lymphoproliferative Krankheit (DE-588)4201162-0 gnd |
| subject_GND | (DE-588)4140169-4 (DE-588)4201162-0 |
| title | The cutaneous lymphoid proliferations a comprehensive textbook of lymphocytic infiltrates of the skin |
| title_auth | The cutaneous lymphoid proliferations a comprehensive textbook of lymphocytic infiltrates of the skin |
| title_exact_search | The cutaneous lymphoid proliferations a comprehensive textbook of lymphocytic infiltrates of the skin |
| title_exact_search_txtP | The cutaneous lymphoid proliferations a comprehensive textbook of lymphocytic infiltrates of the skin |
| title_full | The cutaneous lymphoid proliferations a comprehensive textbook of lymphocytic infiltrates of the skin Cynthia M. Magro, A. Neil Crowson, Martin C. Mihm |
| title_fullStr | The cutaneous lymphoid proliferations a comprehensive textbook of lymphocytic infiltrates of the skin Cynthia M. Magro, A. Neil Crowson, Martin C. Mihm |
| title_full_unstemmed | The cutaneous lymphoid proliferations a comprehensive textbook of lymphocytic infiltrates of the skin Cynthia M. Magro, A. Neil Crowson, Martin C. Mihm |
| title_short | The cutaneous lymphoid proliferations |
| title_sort | the cutaneous lymphoid proliferations a comprehensive textbook of lymphocytic infiltrates of the skin |
| title_sub | a comprehensive textbook of lymphocytic infiltrates of the skin |
| topic | Lymphoproliferative disorders Skin Pathology Skin Tumors Lymphomas Hautkrebs (DE-588)4140169-4 gnd Lymphoproliferative Krankheit (DE-588)4201162-0 gnd |
| topic_facet | Lymphoproliferative disorders Skin Pathology Skin Tumors Lymphomas Hautkrebs Lymphoproliferative Krankheit |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015651262&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015651262&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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