Pharmaceutical compounding and dispensing:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
London [u.a.]
Pharmaceutical Press
2006
|
| Edition: | 1. publ. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XII, 277 S. Ill. 1 CD-ROM (12 cm) |
| ISBN: | 085369575X 9780853695752 |
Staff View
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| 650 | 4 | |a Drug Prescriptions | |
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Record in the Search Index
| _version_ | 1804136177937154048 |
|---|---|
| adam_text | Contents
List of figures vii
List of tables viii
Contents of CD ROM x
About the authors xiii
Preface xiv
Acknowledgements xv
Museum of the Royal Pharmaceutical Society xvi
British Society for the History of Pharmacy xvii
Part 1
History of compounding 1
1 Historical perspective 3
2 Obsolete dosage forms, equipment and methods of preparation 17
3 Historical weights and measures 37
Part 2
Pharmaceutical forms and their preparation 45
4 Key formulation skills 47
5 Extemporaneous dispensing 63
6 Solutions 97
7 Suspensions 111
8 Emulsions 125
VI Contents
9 Creams 147
10 Ointments, pastes and gels 1 55
11 Suppositories and pessaries 173
12 Powders and capsules 185
13 Specialised formulation issues 199
Further reading 207
Part 3
Product formulae 209
Preface 211
14 Creams 217
15 Dusting powders 221
16 Internal mixtures 223
17 Liniments, lotions and applications 243
18 Ointments and pastes 247
19 Powders 251
20 Miscellaneous formulae 253
Appendix
1 Glossary of terms used in formulations 255
2 Abbreviations commonly used in pharmacy 257
3 Changing substance names from British Approved Names to Recommended
International Non Proprietary Names 259
Bibliography 267
Index 269
List of figures
4.1 Diagram to show which edge of the meniscus is to line up with the volume mark 55
4.2 Diagram to show how an error of parallax can occur 55
4.3 Diagram to show which edge of the plunger is to line up with the volume mark
when using a syringe 57
5.1 Example of a dispensing record sheet 68
5.2 The European Chaplet of stars 73
5.3 The European Chaplet of stars with a triangle denoting monographs that have been
adopted by the European Pharmacopoeia Commission from Japan or the
United States of America 73
8.1 Illustration of an oil in water emulsion 126
List of tables
3.1 Relationship between grains, scruples and apothecaries (troy) ounces 37
3.2 Relationship between grains, avoirdupois ounces and avoirdupois pounds 37
3.3 Relationship between minims, fluid drachms, fluid ounces and pints 38
3.4 Historical weighing and measuring units and symbols used in pharmacy 38
3.5 The meaning of different historical symbols used in pharmacy 39
3.6 Dose and quantities table. Where doses and total quantities are ordered in
apothecaries /imperial/avoirdupois systems, the number of doses and the total
quantities in the metric system in column 2 shall be dispensed 40
3.7 Summary conversion table for weights from grains to milligrams or grams 42
3.8 Summary conversion table for volumes from minims to millilitres 43
4.1 Main weighing units used in pharmacy 47
4.2 Traditional balance capabilities 49
4.3 Main volume units used in pharmacy 53
4.4 Numerical value of different solubility descriptions 59
5.1 Examples of different emulsifying bases 77
5.2 Common preservatives used in extemporaneous dispensing along with examples
of extemporaneous preparations containing them 80
5.3 Quantity of boric acid, borax and sodium chloride that is required for a given
pH value 82
5.4 Quantity of sodium acid phosphate, sodium phosphate and sodium chloride
that is required for a given pH value 83
5.5 Composition of three types of emulsifying wax 85
5.6 Flavourings associated with each of the different colourings used in
pharmaceutical preparations intended for internal use 86
5.7 Examples of permitted colours for inclusion in pharmaceutical products in
the UK 87
5.8 Flavourings and examples of preparations in which they are used 88
5.9 Guide to suggested doses of different flavourings commonly used in
pharmaceutical products 89
5.10 Guide to auxiliary labels and discard dates for extemporaneous preparations 90
6.1 Summary of packaging for pharmaceutical solutions 109
7.1 Summary of the different suspending agents used in extemporaneous formulation 113
7.2 Summary of packaging for pharmaceutical suspensions 124
8.1 Different hydrophil—lipophil balance (HLB) ranges and their applications 128
8.2 Hydrophil—lipophil balance (HLB) values of a number of common emulsifying
agents 128
List of tables ix
8.3 Ratio of oily phase to aqueous phase to gum in a primary emulsion 129
8.4 Summary of the problems encountered in emulsion preparation 131
8.5 Summary of packing for pharmaceutical emulsions 144
9.1 Summary of the methods for incorporating solids and liquids into cream and
ointment bases 148
10.1 Choice of preservative to be used in a gel 161
11.1 Displacement values of some common drugs incorporated into suppositories 175
12.1 Common ingredients included in dusting powders and their properties 187
12.2 Approximate capacities of capsules 192
13.1 Relationship between ideal body weight, height and body surface area for
children of different ages and adults 203
Contents of CD ROM
Still images
The following is a list of the images contained on the accompanying CD ROM and an indication
of where the image is referenced in the text.
Chapter 2
1 Bougie moulds, twentieth century. The hinged mould is silver plated to provide a
smooth surface, to prevent the manufactured bougie from sticking to the mould. 19
2 Cachet machines, early twentieth century. The machine on the right is for making
dry seal cachets, and the one at the front is for wet seal cachets. The trough would
contain damp lint, so that the roller could be used to moisten the cachets for sealing. 19
3 Half pint Denby earthenware infusion jar, made by J. Bourne and Son Ltd, probably
nineteenth century. 22
4 Pill making equipment, nineteenth century. 26
5 Plaster irons, nineteenth century. 26
6 A twentieth century syrup bottle and an eighteenth century creamware (ceramic)
syrup jar. 27, 35
7 Tincture bottle and an enamelled metal, single screw tincture press, 1860s. 28
8 (a) A pair of hand scales with box end beam, silver pans and brass apothecary
weights, made by Young and Son, 1814 1815. (b) Chemical scales, made by
Becker and Sons, Rotterdam, nineteenth century. 32
9 A selection of dispensing and domestic measures, nineteenth and twentieth centuries.
(Left to right) horn measure, 2 fluid ounces; graduated glass dispensing measure,
4 fluid ounces; graduated conical dispensing measure calibrated in liquid grains,
a unit rarely used in the UK; stemmed measure in tablespoons and teaspoons; cased
minim (drop) measure. 32
10 Mortars and pestles. (Left to right) ceramic pill mortar and pestle, composition mortar
and pestle, stone mortar with a metal and wooden pestle, bell metal mortar and pestle.
1 1 A selection of spatulas. 33
12 (a) A selection of nineteenth and twentieth century medical preparations: an oxymel,
a medicinal wine, two extracts and a confection, (b) Typical pharmacy bottles,
nineteenth and twentieth centuries, (c) Octagonal bottle embossed with dosage marks
of 1 to 6 ounces, late nineteenth century. 34
13 (a) Collection of nineteenth century carboys, (b) Swan necked carboy, nineteenth
century. 35
Contents of CD ROM xi
Chapter 4
14 Class B balance. 49
15 Class II balance. 49
16 Selection of conical measures (250 mL, 100 mL, 25 mL, 10 mL and 5 mL). 54
Chapter 5
17 Porcelain and glass mortar and pestle. 66
18 Ointment tile and spatulas. 67
19 Selection of pipettes with pipette filler. 67
20 Selection of metal and plastic disposable suppository moulds. The larger metal
mould would be used to manufacture pessaries. 70
21 Counting triangle and capsule counter. 71
22 Water bath and heater. 72
23 Selection of tablet bottles. 94
24 Selection of plain amber medicine bottles. 94
25 Selection of fluted amber medicine bottles. 94
26 Selection of cartons. 95
27 Selection of ointment jars. 95
Chapter 8
28 A homogeniser. 142
Chapter 12
29 A powder trestle. 190
Additional still images on CD ROM
30 Delftware storage jar, labelled O:VULPIN, oil of fox, believed to have been
commissioned by Michael Hastings of Dublin in 1684.
31 Medicine bottles dating from the seventeenth and eighteenth centuries, excavated
in the City of London in the 1950s.
32 Selection of medicines containing opium.
33 Nineteenth century medicine and poison bottles, measures and a cork press.
34 Brass mortar and pestle, probably nineteenth century.
xii Contents of CD ROM
35 Group of objects from the collection of the Museum of the Royal Pharmaceutical
Society.
36 The laboratory, John Bell and Co, 225 Oxford Street, London, painted by
J.G. Murray, 1 840.
Video images
The following is a list of the videos contained on the accompanying CD ROM.
1 Dispensing Solutions (5 minutes, 7 seconds).
2 Dispensing Suspensions (8 minutes, 17 seconds).
3 Dispensing Emulsions (4 minutes, 11 seconds).
4 Dispensing Creams (5 minutes, 13 seconds).
5 Dispensing Ointments (8 minutes, 6 seconds).
6 Dispensing Suppositories (6 minutes, 5 seconds).
7 Dispensing Powders (9 minutes, 35 seconds).
|
| adam_txt |
Contents
List of figures vii
List of tables viii
Contents of CD ROM x
About the authors xiii
Preface xiv
Acknowledgements xv
Museum of the Royal Pharmaceutical Society xvi
British Society for the History of Pharmacy xvii
Part 1
History of compounding 1
1 Historical perspective 3
2 Obsolete dosage forms, equipment and methods of preparation 17
3 Historical weights and measures 37
Part 2
Pharmaceutical forms and their preparation 45
4 Key formulation skills 47
5 Extemporaneous dispensing 63
6 Solutions 97
7 Suspensions 111
8 Emulsions 125
VI Contents
9 Creams 147
10 Ointments, pastes and gels 1 55
11 Suppositories and pessaries 173
12 Powders and capsules 185
13 Specialised formulation issues 199
Further reading 207
Part 3
Product formulae 209
Preface 211
14 Creams 217
15 Dusting powders 221
16 Internal mixtures 223
17 Liniments, lotions and applications 243
18 Ointments and pastes 247
19 Powders 251
20 Miscellaneous formulae 253
Appendix
1 Glossary of terms used in formulations 255
2 Abbreviations commonly used in pharmacy 257
3 Changing substance names from British Approved Names to Recommended
International Non Proprietary Names 259
Bibliography 267
Index 269
List of figures
4.1 Diagram to show which edge of the meniscus is to line up with the volume mark 55
4.2 Diagram to show how an error of parallax can occur 55
4.3 Diagram to show which edge of the plunger is to line up with the volume mark
when using a syringe 57
5.1 Example of a dispensing record sheet 68
5.2 The European Chaplet of stars 73
5.3 The European Chaplet of stars with a triangle denoting monographs that have been
adopted by the European Pharmacopoeia Commission from Japan or the
United States of America 73
8.1 Illustration of an oil in water emulsion 126
List of tables
3.1 Relationship between grains, scruples and apothecaries' (troy) ounces 37
3.2 Relationship between grains, avoirdupois ounces and avoirdupois pounds 37
3.3 Relationship between minims, fluid drachms, fluid ounces and pints 38
3.4 Historical weighing and measuring units and symbols used in pharmacy 38
3.5 The meaning of different historical symbols used in pharmacy 39
3.6 Dose and quantities table. Where doses and total quantities are ordered in
apothecaries'/imperial/avoirdupois systems, the number of doses and the total
quantities in the metric system in column 2 shall be dispensed 40
3.7 Summary conversion table for weights from grains to milligrams or grams 42
3.8 Summary conversion table for volumes from minims to millilitres 43
4.1 Main weighing units used in pharmacy 47
4.2 Traditional balance capabilities 49
4.3 Main volume units used in pharmacy 53
4.4 Numerical value of different solubility descriptions 59
5.1 Examples of different emulsifying bases 77
5.2 Common preservatives used in extemporaneous dispensing along with examples
of extemporaneous preparations containing them 80
5.3 Quantity of boric acid, borax and sodium chloride that is required for a given
pH value 82
5.4 Quantity of sodium acid phosphate, sodium phosphate and sodium chloride
that is required for a given pH value 83
5.5 Composition of three types of emulsifying wax 85
5.6 Flavourings associated with each of the different colourings used in
pharmaceutical preparations intended for internal use 86
5.7 Examples of permitted colours for inclusion in pharmaceutical products in
the UK 87
5.8 Flavourings and examples of preparations in which they are used 88
5.9 Guide to suggested doses of different flavourings commonly used in
pharmaceutical products 89
5.10 Guide to auxiliary labels and discard dates for extemporaneous preparations 90
6.1 Summary of packaging for pharmaceutical solutions 109
7.1 Summary of the different suspending agents used in extemporaneous formulation 113
7.2 Summary of packaging for pharmaceutical suspensions 124
8.1 Different hydrophil—lipophil balance (HLB) ranges and their applications 128
8.2 Hydrophil—lipophil balance (HLB) values of a number of common emulsifying
agents 128
List of tables ix
8.3 Ratio of oily phase to aqueous phase to gum in a primary emulsion 129
8.4 Summary of the problems encountered in emulsion preparation 131
8.5 Summary of packing for pharmaceutical emulsions 144
9.1 Summary of the methods for incorporating solids and liquids into cream and
ointment bases 148
10.1 Choice of preservative to be used in a gel 161
11.1 Displacement values of some common drugs incorporated into suppositories 175
12.1 Common ingredients included in dusting powders and their properties 187
12.2 Approximate capacities of capsules 192
13.1 Relationship between ideal body weight, height and body surface area for
children of different ages and adults 203
Contents of CD ROM
Still images
The following is a list of the images contained on the accompanying CD ROM and an indication
of where the image is referenced in the text.
Chapter 2
1 Bougie moulds, twentieth century. The hinged mould is silver plated to provide a
smooth surface, to prevent the manufactured bougie from sticking to the mould. 19
2 Cachet machines, early twentieth century. The machine on the right is for making
dry seal cachets, and the one at the front is for wet seal cachets. The trough would
contain damp lint, so that the roller could be used to moisten the cachets for sealing. 19
3 Half pint Denby earthenware infusion jar, made by J. Bourne and Son Ltd, probably
nineteenth century. 22
4 Pill making equipment, nineteenth century. 26
5 Plaster irons, nineteenth century. 26
6 A twentieth century syrup bottle and an eighteenth century creamware (ceramic)
syrup jar. 27, 35
7 Tincture bottle and an enamelled metal, single screw tincture press, 1860s. 28
8 (a) A pair of hand scales with box end beam, silver pans and brass apothecary
weights, made by Young and Son, 1814 1815. (b) Chemical scales, made by
Becker and Sons, Rotterdam, nineteenth century. 32
9 A selection of dispensing and domestic measures, nineteenth and twentieth centuries.
(Left to right) horn measure, 2 fluid ounces; graduated glass dispensing measure,
4 fluid ounces; graduated conical dispensing measure calibrated in liquid grains,
a unit rarely used in the UK; stemmed measure in tablespoons and teaspoons; cased
minim (drop) measure. 32
10 Mortars and pestles. (Left to right) ceramic pill mortar and pestle, composition mortar
and pestle, stone mortar with a metal and wooden pestle, bell metal mortar and pestle.
1 1 A selection of spatulas. 33
12 (a) A selection of nineteenth and twentieth century medical preparations: an oxymel,
a medicinal wine, two extracts and a confection, (b) Typical pharmacy bottles,
nineteenth and twentieth centuries, (c) Octagonal bottle embossed with dosage marks
of 1 to 6 ounces, late nineteenth century. 34
13 (a) Collection of nineteenth century carboys, (b) Swan necked carboy, nineteenth
century. 35
Contents of CD ROM xi
Chapter 4
14 Class B balance. 49
15 Class II balance. 49
16 Selection of conical measures (250 mL, 100 mL, 25 mL, 10 mL and 5 mL). 54
Chapter 5
17 Porcelain and glass mortar and pestle. 66
18 Ointment tile and spatulas. 67
19 Selection of pipettes with pipette filler. 67
20 Selection of metal and plastic disposable suppository moulds. The larger metal
mould would be used to manufacture pessaries. 70
21 Counting triangle and capsule counter. 71
22 Water bath and heater. 72
23 Selection of tablet bottles. 94
24 Selection of plain amber medicine bottles. 94
25 Selection of fluted amber medicine bottles. 94
26 Selection of cartons. 95
27 Selection of ointment jars. 95
Chapter 8
28 A homogeniser. 142
Chapter 12
29 A powder trestle. 190
Additional still images on CD ROM
30 Delftware storage jar, labelled O:VULPIN, oil of fox, believed to have been
commissioned by Michael Hastings of Dublin in 1684.
31 Medicine bottles dating from the seventeenth and eighteenth centuries, excavated
in the City of London in the 1950s.
32 Selection of medicines containing opium.
33 Nineteenth century medicine and poison bottles, measures and a cork press.
34 Brass mortar and pestle, probably nineteenth century.
xii Contents of CD ROM
35 Group of objects from the collection of the Museum of the Royal Pharmaceutical
Society.
36 The laboratory, John Bell and Co, 225 Oxford Street, London, painted by
J.G. Murray, 1 840.
Video images
The following is a list of the videos contained on the accompanying CD ROM.
1 Dispensing Solutions (5 minutes, 7 seconds).
2 Dispensing Suspensions (8 minutes, 17 seconds).
3 Dispensing Emulsions (4 minutes, 11 seconds).
4 Dispensing Creams (5 minutes, 13 seconds).
5 Dispensing Ointments (8 minutes, 6 seconds).
6 Dispensing Suppositories (6 minutes, 5 seconds).
7 Dispensing Powders (9 minutes, 35 seconds). |
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| illustrated | Illustrated |
| index_date | 2024-07-02T16:24:25Z |
| indexdate | 2024-07-09T20:52:16Z |
| institution | BVB |
| isbn | 085369575X 9780853695752 |
| language | English |
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| physical | XII, 277 S. Ill. 1 CD-ROM (12 cm) |
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| publisher | Pharmaceutical Press |
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| spelling | Pharmaceutical compounding and dispensing John F. Marriott ... 1. publ. London [u.a.] Pharmaceutical Press 2006 XII, 277 S. Ill. 1 CD-ROM (12 cm) txt rdacontent n rdamedia nc rdacarrier Labortechnik swd Médicaments - Formes pharmaceutiques Pharmazeutische Technologie swd Dosage Forms Drug Compounding methods Drug Prescriptions Drugs Dosage forms Pharmaceutical Services Pharmacy Marriott, John F. Sonstige oth HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015412770&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Pharmaceutical compounding and dispensing Labortechnik swd Médicaments - Formes pharmaceutiques Pharmazeutische Technologie swd Dosage Forms Drug Compounding methods Drug Prescriptions Drugs Dosage forms Pharmaceutical Services Pharmacy |
| title | Pharmaceutical compounding and dispensing |
| title_auth | Pharmaceutical compounding and dispensing |
| title_exact_search | Pharmaceutical compounding and dispensing |
| title_exact_search_txtP | Pharmaceutical compounding and dispensing |
| title_full | Pharmaceutical compounding and dispensing John F. Marriott ... |
| title_fullStr | Pharmaceutical compounding and dispensing John F. Marriott ... |
| title_full_unstemmed | Pharmaceutical compounding and dispensing John F. Marriott ... |
| title_short | Pharmaceutical compounding and dispensing |
| title_sort | pharmaceutical compounding and dispensing |
| topic | Labortechnik swd Médicaments - Formes pharmaceutiques Pharmazeutische Technologie swd Dosage Forms Drug Compounding methods Drug Prescriptions Drugs Dosage forms Pharmaceutical Services Pharmacy |
| topic_facet | Labortechnik Médicaments - Formes pharmaceutiques Pharmazeutische Technologie Dosage Forms Drug Compounding methods Drug Prescriptions Drugs Dosage forms Pharmaceutical Services Pharmacy |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=015412770&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT marriottjohnf pharmaceuticalcompoundinganddispensing |