Chirality in Drug Research:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Weinheim
WILEY-VCH
2006
|
| Series: | Methods and Principles in Medicinal Chemistry
33 |
| Subjects: | |
| Online Access: | Inhaltstext Inhaltsverzeichnis |
| Physical Description: | XIX, 351 S. Ill., graph. Darst. 240 mm x 170 mm |
| ISBN: | 3527310762 9783527310760 |
Staff View
MARC
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Record in the Search Index
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| adam_text | Contents
Prefece
List of Contributors XV
Introduction
1
Joseph
1.1
1.2
1.3
1.4
1.5
The Beginnings
1.6
References
Synthesis
2
Hans-Jürgen Federsei
2.1
2.2
2.3
Drivers and
2.4
2.5
2.6
2.6.1
2.6.2
2.6.3
2.7
References
Chirality in Drug Research. Edited by Eric Francotte and Wolfgang Lindner
Copyright
ISBN:
VI
3
Philipp
and Ansgar Schuffenhauer
3.1
3.2
3.2.1
Synthetics
3.2.2
Natural Products
3.2.2.1
3.2.2.2
3.2.2.3
3.2.2.4
3.3
Biosynthesis
3.3.1
3.3.2
3.3.3
3.3.4
3.4
3.4.1
3.4.2
3.4.3
3.4.4
References
4 Biotransformation
Intermediates
Michael
4.1
4.2
of Pharmaceuticals
4.2.1
4.2.2
4.2.3
4.2.4
4.2.5
4.2.6
4.2.7
4.2.8
4.3
4.3.1
4.3.2
4.3.3
4.3.4
Contents
4.3.5 Metabolie Engineering 116
4.3.6
4.4
References
Separations
5 Resolution
by Crystallisation
Kazuhiko Saigo
5.1
5.2
5.3
5.4
Salt Formation
5.5
by Diastereomeric Salt Formation
5.5.1
Salts -A Key Intermediate for the Synthesis of Duloxetine,3-(Methyl-
amino)-l-(2-thienyl)propan-l-ol
5.5.2
ACE Inhibitors, 2-Hydroxy-4-phenylbutyric Acid, and l-(4-Methyl-
phenyl)ethylamine
5.5.3
a-Amino-Ê-caprolactam
5.6
References
6
Chromatography
Eric Francotte
6.1
6.2
Stereoisomers of Chiral Drugs
6.2.1
6.2.2
6.3
6.3.1
6.3.2
6.3.2.1
6.3.2.2
6.3.2.3
6.3.3
6.3.3.1
VIH I
6.3.3.2
6.3.3.3
6.3.3.4
6.4
6.4.1
6.4.2
6.4.3
6.5
6.5.1
6.5.2
6.5.3
6.5.4
6.5
6.5.1
6.5.2
6.5.3
6.5.4
6.6
References
7
Norbert M. Maierand
7.1
7.2
7.3
7.4
7.4.1
7.4.2
7.4.2.1
7.4.2.2
7.5
7.6
7.7
7.8
Liquid
7.8.1
7.8.1.1
7.8.1.1.1
7.8.1.1.2
7.8.1.2
7.8.1.2.1
7.8.1.2.2
7.8.1.2.3
7.8.1.2.4
7.8.1.2.5
Contents
7.8.2
7.8.2.1
7.8.2.2
7.8.2.3
7.8.3
7.8.3.1
7.8.3.2
7.8.3.2
7.
7.8.4.1
7.8.4.2
7.9
References
8
Drugs Analysis
Serge Rudaz and Jean-Luc Veuthey
8.1
8.2
8.3
8.3.1
8.3.2
8.4
8.5
8.5.1
8.5.2
8.6
8.6.1
8.6.2
8.7
8.8
Coupling
8.9
8.10
References
9
and Simultaneous Determination of Their Absolute Configurations by
X-Ray Crystallography and/or1
Nobuyuki Harada
9.1
9.2
9.2.1
Chiral Compounds
Xl Contents
9.2.2 Relative
Configuration Using an Internal Reference of Absolute
Configuration
9.3
for the Enantioresolution of Alcohols by HPLC and Simultaneous
Determination of Their Absolute Configurations by X-ray
Crystallography
9.4
(MaNP Acid (S)-(+)-3), Useful for Enantioresolution of Alcohols and
Simultaneous Determination of Their Absolute Configurations by the
*H NMR Anisotropy Method
9.4.1
Natural (-)-Menthol
9.4.2
Configuration of Secondary Alcohols: the Sector Rule and
Applications
9.4.3
Simultaneous Determination of Their Absolute Configurations
9.4.4
Alcohols
9.4.5
Diphenylmethanols
9.5
as Determined by the aH NMR Anisotropy Method with MaNP
Acid
9.6
References
10
Software and Literature Research on Chirality in Modeling, Chirality in
Docking, Chiral Ligand-Receptor Interaction and Symmetry
Gerd Folkers,
10.1
10.2
10.3
10.4
10.5
10.5.1 DNA 327
10.5.2
10.5.3
10.5.4
10.6
10.7
References to Its Successful Application
Contents
10.7.1
Program
10.7.2
10.7.3
10.7.4
10.7.5
Calculations
10.7.6
10.7.7 Schrödinger-
10.7.8
10.7.9 MOE -
References
Subject Index
|
| adam_txt |
Contents
Prefece
List of Contributors XV
Introduction
1
Joseph
1.1
1.2
1.3
1.4
1.5
The Beginnings
1.6
References
Synthesis
2
Hans-Jürgen Federsei
2.1
2.2
2.3
Drivers and
2.4
2.5
2.6
2.6.1
2.6.2
2.6.3
2.7
References
Chirality in Drug Research. Edited by Eric Francotte and Wolfgang Lindner
Copyright
ISBN:
VI
3
Philipp
and Ansgar Schuffenhauer
3.1
3.2
3.2.1
Synthetics
3.2.2
Natural Products
3.2.2.1
3.2.2.2
3.2.2.3
3.2.2.4
3.3
Biosynthesis
3.3.1
3.3.2
3.3.3
3.3.4
3.4
3.4.1
3.4.2
3.4.3
3.4.4
References
4 Biotransformation
Intermediates
Michael
4.1
4.2
of Pharmaceuticals
4.2.1
4.2.2
4.2.3
4.2.4
4.2.5
4.2.6
4.2.7
4.2.8
4.3
4.3.1
4.3.2
4.3.3
4.3.4
Contents
4.3.5 Metabolie Engineering 116
4.3.6
4.4
References
Separations
5 Resolution
by Crystallisation
Kazuhiko Saigo
5.1
5.2
5.3
5.4
Salt Formation
5.5
by Diastereomeric Salt Formation
5.5.1
Salts -A Key Intermediate for the Synthesis of Duloxetine,3-(Methyl-
amino)-l-(2-thienyl)propan-l-ol
5.5.2
ACE Inhibitors, 2-Hydroxy-4-phenylbutyric Acid, and l-(4-Methyl-
phenyl)ethylamine
5.5.3
a-Amino-Ê-caprolactam
5.6
References
6
Chromatography
Eric Francotte
6.1
6.2
Stereoisomers of Chiral Drugs
6.2.1
6.2.2
6.3
6.3.1
6.3.2
6.3.2.1
6.3.2.2
6.3.2.3
6.3.3
6.3.3.1
VIH I
6.3.3.2
6.3.3.3
6.3.3.4
6.4
6.4.1
6.4.2
6.4.3
6.5
6.5.1
6.5.2
6.5.3
6.5.4
6.5
6.5.1
6.5.2
6.5.3
6.5.4
6.6
References
7
Norbert M. Maierand
7.1
7.2
7.3
7.4
7.4.1
7.4.2
7.4.2.1
7.4.2.2
7.5
7.6
7.7
7.8
Liquid
7.8.1
7.8.1.1
7.8.1.1.1
7.8.1.1.2
7.8.1.2
7.8.1.2.1
7.8.1.2.2
7.8.1.2.3
7.8.1.2.4
7.8.1.2.5
Contents
7.8.2
7.8.2.1
7.8.2.2
7.8.2.3
7.8.3
7.8.3.1
7.8.3.2
7.8.3.2
7.
7.8.4.1
7.8.4.2
7.9
References
8
Drugs Analysis
Serge Rudaz and Jean-Luc Veuthey
8.1
8.2
8.3
8.3.1
8.3.2
8.4
8.5
8.5.1
8.5.2
8.6
8.6.1
8.6.2
8.7
8.8
Coupling
8.9
8.10
References
9
and Simultaneous Determination of Their Absolute Configurations by
X-Ray Crystallography and/or1
Nobuyuki Harada
9.1
9.2
9.2.1
Chiral Compounds
Xl Contents
9.2.2 Relative
Configuration Using an Internal Reference of Absolute
Configuration
9.3
for the Enantioresolution of Alcohols by HPLC and Simultaneous
Determination of Their Absolute Configurations by X-ray
Crystallography
9.4
(MaNP Acid (S)-(+)-3), Useful for Enantioresolution of Alcohols and
Simultaneous Determination of Their Absolute Configurations by the
*H NMR Anisotropy Method
9.4.1
Natural (-)-Menthol
9.4.2
Configuration of Secondary Alcohols: the Sector Rule and
Applications
9.4.3
Simultaneous Determination of Their Absolute Configurations
9.4.4
Alcohols
9.4.5
Diphenylmethanols
9.5
as Determined by the aH NMR Anisotropy Method with MaNP
Acid
9.6
References
10
Software and Literature Research on Chirality in Modeling, Chirality in
Docking, Chiral Ligand-Receptor Interaction and Symmetry
Gerd Folkers,
10.1
10.2
10.3
10.4
10.5
10.5.1 DNA 327
10.5.2
10.5.3
10.5.4
10.6
10.7
References to Its Successful Application
Contents
10.7.1
Program
10.7.2
10.7.3
10.7.4
10.7.5
Calculations
10.7.6
10.7.7 Schrödinger-
10.7.8
10.7.9 MOE -
References
Subject Index |
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| bvnumber | BV021754707 |
| callnumber-first | R - Medicine |
| callnumber-label | RM301 |
| callnumber-raw | RM301.25 RS429 |
| callnumber-search | RM301.25 RS429 |
| callnumber-sort | RM 3301.25 |
| callnumber-subject | RM - Therapeutics and Pharmacology |
| classification_rvk | VS 5350 |
| ctrlnum | (OCoLC)67873889 (DE-599)BVBBV021754707 |
| dewey-full | 615.19 |
| dewey-hundreds | 600 - Technology (Applied sciences) |
| dewey-ones | 615 - Pharmacology and therapeutics |
| dewey-raw | 615.19 |
| dewey-search | 615.19 |
| dewey-sort | 3615.19 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Medizin |
| discipline_str_mv | Chemie / Pharmazie Medizin |
| format | Book |
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| genre_facet | Aufsatzsammlung |
| id | DE-604.BV021754707 |
| illustrated | Illustrated |
| index_date | 2024-07-02T15:33:08Z |
| indexdate | 2024-07-09T20:43:18Z |
| institution | BVB |
| isbn | 3527310762 9783527310760 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-014967887 |
| oclc_num | 67873889 |
| open_access_boolean | |
| owner | DE-29T DE-355 DE-BY-UBR DE-19 DE-BY-UBM |
| owner_facet | DE-29T DE-355 DE-BY-UBR DE-19 DE-BY-UBM |
| physical | XIX, 351 S. Ill., graph. Darst. 240 mm x 170 mm |
| publishDate | 2006 |
| publishDateSearch | 2006 |
| publishDateSort | 2006 |
| publisher | WILEY-VCH |
| record_format | marc |
| series | Methods and Principles in Medicinal Chemistry |
| series2 | Methods and Principles in Medicinal Chemistry |
| spelling | Chirality in Drug Research ed. by Eric Francotte ... Weinheim WILEY-VCH 2006 XIX, 351 S. Ill., graph. Darst. 240 mm x 170 mm txt rdacontent n rdamedia nc rdacarrier Methods and Principles in Medicinal Chemistry 33 Médicaments - Développement Médicaments - Recherche Chemistry, Pharmaceutical Chiral drugs Drug Design Drug development Drugs Research Molecular Conformation Stereoisomerism Chiralität Chemie (DE-588)4147732-7 gnd rswk-swf Arzneimitteldesign (DE-588)4278218-1 gnd rswk-swf Arzneimittelforschung (DE-588)4003120-2 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Chiralität Chemie (DE-588)4147732-7 s Arzneimitteldesign (DE-588)4278218-1 s DE-604 Arzneimittelforschung (DE-588)4003120-2 s b DE-604 Francotte, Eric Sonstige (DE-588)13212937X oth Methods and Principles in Medicinal Chemistry 33 (DE-604)BV035418617 33 text/html http://deposit.dnb.de/cgi-bin/dokserv?id=2708220&prov=M&dok_var=1&dok_ext=htm Inhaltstext Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014967887&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Chirality in Drug Research Methods and Principles in Medicinal Chemistry Médicaments - Développement Médicaments - Recherche Chemistry, Pharmaceutical Chiral drugs Drug Design Drug development Drugs Research Molecular Conformation Stereoisomerism Chiralität Chemie (DE-588)4147732-7 gnd Arzneimitteldesign (DE-588)4278218-1 gnd Arzneimittelforschung (DE-588)4003120-2 gnd |
| subject_GND | (DE-588)4147732-7 (DE-588)4278218-1 (DE-588)4003120-2 (DE-588)4143413-4 |
| title | Chirality in Drug Research |
| title_auth | Chirality in Drug Research |
| title_exact_search | Chirality in Drug Research |
| title_exact_search_txtP | Chirality in Drug Research |
| title_full | Chirality in Drug Research ed. by Eric Francotte ... |
| title_fullStr | Chirality in Drug Research ed. by Eric Francotte ... |
| title_full_unstemmed | Chirality in Drug Research ed. by Eric Francotte ... |
| title_short | Chirality in Drug Research |
| title_sort | chirality in drug research |
| topic | Médicaments - Développement Médicaments - Recherche Chemistry, Pharmaceutical Chiral drugs Drug Design Drug development Drugs Research Molecular Conformation Stereoisomerism Chiralität Chemie (DE-588)4147732-7 gnd Arzneimitteldesign (DE-588)4278218-1 gnd Arzneimittelforschung (DE-588)4003120-2 gnd |
| topic_facet | Médicaments - Développement Médicaments - Recherche Chemistry, Pharmaceutical Chiral drugs Drug Design Drug development Drugs Research Molecular Conformation Stereoisomerism Chiralität Chemie Arzneimitteldesign Arzneimittelforschung Aufsatzsammlung |
| url | http://deposit.dnb.de/cgi-bin/dokserv?id=2708220&prov=M&dok_var=1&dok_ext=htm http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014967887&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV035418617 |
| work_keys_str_mv | AT francotteeric chiralityindrugresearch |