Exploring the vertebrate central cholinergic nervous system:
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| Format: | Book |
|---|---|
| Language: | English |
| Published: |
New York, NY
Springer
2007
|
| Subjects: | |
| Online Access: | Inhaltstext Inhaltsverzeichnis |
| Physical Description: | XIII, 686 S. Ill., graph. Darst. |
| ISBN: | 9780387282237 0387282238 |
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| 245 | 1 | 0 | |a Exploring the vertebrate central cholinergic nervous system |c Alexander G. Karczmar. With contributions by Neelima Chauhan ...With a foreword by Victor P. Whittaker |
| 264 | 1 | |a New York, NY |b Springer |c 2007 | |
| 300 | |a XIII, 686 S. |b Ill., graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
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| 650 | 4 | |a Acetylcholine | |
| 650 | 4 | |a Acetylcholine |x Receptors | |
| 650 | 4 | |a Central Nervous System |x physiology | |
| 650 | 4 | |a Central nervous system | |
| 650 | 4 | |a Cholinergic Agents | |
| 650 | 4 | |a Cholinergic Fibers | |
| 650 | 4 | |a Cholinergic mechanisms | |
| 650 | 4 | |a Cholinesterases | |
| 650 | 4 | |a Neural transmission | |
| 650 | 4 | |a Receptors, Cholinergic | |
| 650 | 4 | |a Synaptic Transmission |x physiology | |
| 650 | 4 | |a Vertebrates | |
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| adam_text | Contents
Foreword by Victor P. Whittaker
Preface and Acknowledgments
Contributors
1.
A. Why a Book on the Central Cholinergic System?
B. Outline of the History of Central Cholinergic System Research
С
D. Envoi
Notes
References
2.
A. History of Methodological Development Needed to Define
the Cholinergic Neuron, Explain Acetylcholine Releae, and Establish
Central Cholinergic Pathways
B. Morphology and Cytoanatomy, and Markers of Central Cholinergic Neurons.
C. Classical and Unorthodox Hypotheses of Acetylcholine Release
DI.
DII.
Expanded by Butcher,
DIII.
Other Recent Investigators
DIV.
Notes
References
3.
A. Historical Introduction
B. ACh Synthesis
CI. Choline
CII.
CIII.
Phospholipids
Contents
CIV. Choline Transport
DI. Cholinesterases.................................................. 109
DU.
DIII.
Notes
References
4.
Cholinergic Receptors
Alexander G. Karczmar,
A. Curare,
B. Receptors and the Demonstration of Cholinergic Transmission
C. The Abstract Phase of the Receptor Research
D. The Reality of the Receptors
E. Receptor Subtypes
F. Brief Conclusions
Notes
References
5.
System: Structure, Function, and Pharmacology
Arthur Christopoulos
A. Introduction
B. Pharmacological Classification
С
D. Molecular Biology
E. Signaling Pathways
F. Functional Insights Gained from the Use of Muscarinic Acetylcholine
Receptor Knockout Mice
G. Conclusions
Acknowledgments
References
6. Neuronal
Functional Roles
Jon Lindstrom
A. Scope of the Chapter
B. Structures of Nicotinic Acetylcholine Receptors
C. Functional Roles of Nicotinic Receptors
References
7.
A. Historical Introduction
BI. Classification. Chemical Structures. Structure-Activity Relationships,
and Bonding Relationships of Anticholinesterases
BH. Organophosphorus
and Bonding
Contents
BUI.
Anticholinesterases............................................... 265
C.
DI.
DII. Toxic
E. Treatment of Anticholinesterase Poisoning
F. Cholinergic Teratology
Notes
References
8.
A. Historical Introduction
BI. Cholinergic Ontogeny: Precocious Developmental Appearance of
the Components of the Cholinergic System
BII.
and
BUI.
BIV.
BV. Phylogenesis of the Cholinergic System
С
CI.
CII.
CHI. Anterograde-Acting
D.
Cholinergic Agents
Notes
References
9.
A. Scope of This Chapter and Historical Introduction
BI. Cholinoceptive Responses
BII.
Bill. Pharmacology of Central Cholinergic and Cholinomimetic Responses
BIV.
BV. Mental and Behavioral Functions with Cholinergic Implications
BVI. Cholinergic Aspects of Organism-Environment Interaction
Notes
References
10.
Disease and Their Cholinergic Aspects
George S.
A. Historical Introduction
B. Dysregulated Processing of Neurocellular Proteins
C. Amyloid
D. Amyloid Precursor Protein
xii Contents
E.
F. ß-Secretase ..................................................... 615
G. y-Secretase
H.
I. Tau Biology
J. Potential Regulatory Interactions in the Pathogenesis of Alzheimer s Disease
K. Therapy of Alzheimer s Disease and Future Directions
Notes
References
11.
A. Immediate, Mundane Concerns
B. The Far Beyond Matters
С
Notes
References
Index
|
| adam_txt |
Contents
Foreword by Victor P. Whittaker
Preface and Acknowledgments
Contributors
1.
A. Why a Book on the Central Cholinergic System?
B. Outline of the History of Central Cholinergic System Research
С
D. Envoi
Notes
References
2.
A. History of Methodological Development Needed to Define
the Cholinergic Neuron, Explain Acetylcholine Releae, and Establish
Central Cholinergic Pathways
B. Morphology and Cytoanatomy, and Markers of Central Cholinergic Neurons.
C. Classical and Unorthodox Hypotheses of Acetylcholine Release
DI.
DII.
Expanded by Butcher,
DIII.
Other Recent Investigators
DIV.
Notes
References
3.
A. Historical Introduction
B. ACh Synthesis
CI. Choline
CII.
CIII.
Phospholipids
Contents
CIV. Choline Transport
DI. Cholinesterases. 109
DU.
DIII.
Notes
References
4.
Cholinergic Receptors
Alexander G. Karczmar,
A. Curare,
B. Receptors and the Demonstration of Cholinergic Transmission
C. The "Abstract" Phase of the Receptor Research
D. The Reality of the Receptors
E. Receptor Subtypes
F. Brief Conclusions
Notes
References
5.
System: Structure, Function, and Pharmacology
Arthur Christopoulos
A. Introduction
B. Pharmacological Classification
С
D. Molecular Biology
E. Signaling Pathways
F. Functional Insights Gained from the Use of Muscarinic Acetylcholine
Receptor Knockout Mice
G. Conclusions
Acknowledgments
References
6. Neuronal
Functional Roles
Jon Lindstrom
A. Scope of the Chapter
B. Structures of Nicotinic Acetylcholine Receptors
C. Functional Roles of Nicotinic Receptors
References
7.
A. Historical Introduction
BI. Classification. Chemical Structures. Structure-Activity Relationships,
and Bonding Relationships of Anticholinesterases
BH. Organophosphorus
and Bonding
Contents
BUI.
Anticholinesterases. 265
C.
DI.
DII. Toxic
E. Treatment of Anticholinesterase Poisoning
F. Cholinergic Teratology
Notes
References
8.
A. Historical Introduction
BI. Cholinergic Ontogeny: Precocious Developmental Appearance of
the Components of the Cholinergic System
BII.
and
BUI.
BIV.
BV. Phylogenesis of the Cholinergic System
С
CI.
CII.
CHI. Anterograde-Acting
D.
Cholinergic Agents
Notes
References
9.
A. Scope of This Chapter and Historical Introduction
BI. Cholinoceptive Responses
BII.
Bill. Pharmacology of Central Cholinergic and Cholinomimetic Responses
BIV.
BV. Mental and Behavioral Functions with Cholinergic Implications
BVI. Cholinergic Aspects of Organism-Environment Interaction
Notes
References
10.
Disease and Their Cholinergic Aspects
George S.
A. Historical Introduction
B. Dysregulated Processing of Neurocellular Proteins
C. Amyloid
D. Amyloid Precursor Protein
xii Contents
E.
F. ß-Secretase . 615
G. y-Secretase
H.
I. Tau Biology
J. Potential Regulatory Interactions in the Pathogenesis of Alzheimer's Disease
K. Therapy of Alzheimer's Disease and Future Directions
Notes
References
11.
A. Immediate, Mundane Concerns
B. The "Far Beyond" Matters
С
Notes
References
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| spelling | Exploring the vertebrate central cholinergic nervous system Alexander G. Karczmar. With contributions by Neelima Chauhan ...With a foreword by Victor P. Whittaker New York, NY Springer 2007 XIII, 686 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Acetylcholine Acetylcholine Receptors Central Nervous System physiology Central nervous system Cholinergic Agents Cholinergic Fibers Cholinergic mechanisms Cholinesterases Neural transmission Receptors, Cholinergic Synaptic Transmission physiology Vertebrates Wirbeltiere (DE-588)4066376-0 gnd rswk-swf Cholinerges System (DE-588)4147867-8 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Wirbeltiere (DE-588)4066376-0 s Cholinerges System (DE-588)4147867-8 s b DE-604 Karczmar, Alexander G. 1918- Sonstige (DE-588)107929783 oth text/html http://deposit.dnb.de/cgi-bin/dokserv?id=2738225&prov=M&dok_var=1&dok_ext=htm Inhaltstext Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014963156&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Exploring the vertebrate central cholinergic nervous system Acetylcholine Acetylcholine Receptors Central Nervous System physiology Central nervous system Cholinergic Agents Cholinergic Fibers Cholinergic mechanisms Cholinesterases Neural transmission Receptors, Cholinergic Synaptic Transmission physiology Vertebrates Wirbeltiere (DE-588)4066376-0 gnd Cholinerges System (DE-588)4147867-8 gnd |
| subject_GND | (DE-588)4066376-0 (DE-588)4147867-8 (DE-588)4143413-4 |
| title | Exploring the vertebrate central cholinergic nervous system |
| title_auth | Exploring the vertebrate central cholinergic nervous system |
| title_exact_search | Exploring the vertebrate central cholinergic nervous system |
| title_exact_search_txtP | Exploring the vertebrate central cholinergic nervous system |
| title_full | Exploring the vertebrate central cholinergic nervous system Alexander G. Karczmar. With contributions by Neelima Chauhan ...With a foreword by Victor P. Whittaker |
| title_fullStr | Exploring the vertebrate central cholinergic nervous system Alexander G. Karczmar. With contributions by Neelima Chauhan ...With a foreword by Victor P. Whittaker |
| title_full_unstemmed | Exploring the vertebrate central cholinergic nervous system Alexander G. Karczmar. With contributions by Neelima Chauhan ...With a foreword by Victor P. Whittaker |
| title_short | Exploring the vertebrate central cholinergic nervous system |
| title_sort | exploring the vertebrate central cholinergic nervous system |
| topic | Acetylcholine Acetylcholine Receptors Central Nervous System physiology Central nervous system Cholinergic Agents Cholinergic Fibers Cholinergic mechanisms Cholinesterases Neural transmission Receptors, Cholinergic Synaptic Transmission physiology Vertebrates Wirbeltiere (DE-588)4066376-0 gnd Cholinerges System (DE-588)4147867-8 gnd |
| topic_facet | Acetylcholine Acetylcholine Receptors Central Nervous System physiology Central nervous system Cholinergic Agents Cholinergic Fibers Cholinergic mechanisms Cholinesterases Neural transmission Receptors, Cholinergic Synaptic Transmission physiology Vertebrates Wirbeltiere Cholinerges System Aufsatzsammlung |
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