Cancer drug resistance:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2006
|
| Schriftenreihe: | Cancer drug discovery and development
|
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | XVI, 617 S. Ill., graph. Darst. 27 cm |
| ISBN: | 1588295303 9781588295309 |
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| 245 | 1 | 0 | |a Cancer drug resistance |c ed. by Beverly A. Teicher |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2006 | |
| 300 | |a XVI, 617 S. |b Ill., graph. Darst. |c 27 cm | ||
| 336 | |b txt |2 rdacontent | ||
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| 490 | 0 | |a Cancer drug discovery and development | |
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Cellules cancéreuses - Résistance aux médicaments | |
| 650 | 4 | |a Antineoplastic Agents |x therapeutic use | |
| 650 | 4 | |a Drug Resistance, Neoplasm | |
| 650 | 4 | |a Drug resistance in cancer cells | |
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Datensatz im Suchindex
| _version_ | 1804135564664897536 |
|---|---|
| adam_text | Contents
Preface
Contributors
PART I. Physiological Resistance
1
Mark W. Dewhirst, Yiting
2
Chang W. Song, Robert Griffin, andHeon Joo Park
3
Sarah Jane
4
The Role of Evolving Interrelationships
Between Cancer Cells and Host Tissues
Janusz W. Rak,
5
David A. Mankoff and Kenneth A. Krohn
PART II: Biological Resistance
6
of More Effective Therapies
Ilia Mantle,
7
William R. Waud
8
Aníbal
9
Beverly A. Teicher
10
Vladislava O. Melnikova
11
Patrice J. Morin
ix
Contents
PART III. Biochemical Resistance
12
Victoria J. Findlay, Danyelle M. Townsend,
and Kenneth D. Tew
13
Faiyaz Notta and D. James Koropatnick
14
in Cancer Cells and Tumors
Elena Monti
15
Sestamibi, SNPs, Substrates, and Stem Cells
Susan E. Bates, John Deeken, Chaohong Fan,
and Robert W. Robey
16
Zahid H. Siddik
17
of Cisplatin by Copper Transporters
Roohangiz Safaei and Stephen B. Howell
18
Lee M.
19
Jens M. Teodoridis and Robert Brown
20
Lori A. Hazlehurst and William S.
21
George W. Sledge, Jr., Kathy D. Miller, Bryan Schneider,
and Christopher J. Sweeney
PART IV. The Role of Hormones, Growth Factors, and Oncogenes
22
Clodia Osipo and Ruth M. O Regan
23
in Multiple Myeloma
Varsha Gandhi and
24
Ingrid
Contents xi
25
Jan Pinkas and Beverly A. Teicher
26
Albert B. DeLeo
27
Paul Dent, Adly Yacoub, Michael P.
28
of Acquired Drug Resistance
M. Jim Yen, Ie-Ming Shih, Victor E. Velculescu, and Tian-Li Wang
PART V. Clinical Aspects of Resistance
29
Mika
30
Toward Tailored Cancer Therapies
Kristin Kee and Jeffrey E. Green
31
Yi TingKoh, M.
Index
As genomic techniques gradually reveal the ability of malignant cells to respond to chemical and biological insults with
remarkable flexibility of phenotype, it becomes clear that much remains to be done to control and eliminate such cells. In
Cancer Drug Resistance, leading scientists from the best academic institutions and industrial laboratories summarize and
synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to a wide variety
of
therapeutic opportunities. The authors review physiological resistance based on tumor architecture, cellular resistance
based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug
target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to
antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the
development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene ampli¬
fication in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin®.
Authoritative and insightful, Cancer Drug Res/stance offers basic and clinical investigators a state-of-the-art synthesis of the
many faceted research now available on the biology and genetics of tumor resistance, as well as exciting new approaches
to its prevention and eradication.
|
| adam_txt |
Contents
Preface
Contributors
PART I. Physiological Resistance
1
Mark W. Dewhirst, Yiting
2
Chang W. Song, Robert Griffin, andHeon Joo Park
3
Sarah Jane
4
The Role of Evolving Interrelationships
Between Cancer Cells and Host Tissues
Janusz W. Rak,
5
David A. Mankoff and Kenneth A. Krohn
PART II: Biological Resistance
6
of More Effective Therapies
Ilia Mantle,
7
William R. Waud
8
Aníbal
9
Beverly A. Teicher
10
Vladislava O. Melnikova
11
Patrice J. Morin
ix
Contents
PART III. Biochemical Resistance
12
Victoria J. Findlay, Danyelle M. Townsend,
and Kenneth D. Tew
13
Faiyaz Notta and D. James Koropatnick
14
in Cancer Cells and Tumors
Elena Monti
15
Sestamibi, SNPs, Substrates, and Stem Cells
Susan E. Bates, John Deeken, Chaohong Fan,
and Robert W. Robey
16
Zahid H. Siddik
17
of Cisplatin by Copper Transporters
Roohangiz Safaei and Stephen B. Howell
18
Lee M.
19
Jens M. Teodoridis and Robert Brown
20
Lori A. Hazlehurst and William S.
21
George W. Sledge, Jr., Kathy D. Miller, Bryan Schneider,
and Christopher J. Sweeney
PART IV. The Role of Hormones, Growth Factors, and Oncogenes
22
Clodia Osipo and Ruth M. O'Regan
23
in Multiple Myeloma
Varsha Gandhi and
24
Ingrid
Contents xi
25
Jan Pinkas and Beverly A. Teicher
26
Albert B. DeLeo
27
Paul Dent, Adly Yacoub, Michael P.
28
of Acquired Drug Resistance
M. Jim Yen, Ie-Ming Shih, Victor E. Velculescu, and Tian-Li Wang
PART V. Clinical Aspects of Resistance
29
Mika
30
Toward Tailored Cancer Therapies
Kristin Kee and Jeffrey E. Green
31
Yi TingKoh, M.
Index
As genomic techniques gradually reveal the ability of malignant cells to respond to chemical and biological insults with
remarkable flexibility of phenotype, it becomes clear that much remains to be done to control and eliminate such cells. In
Cancer Drug Resistance, leading scientists from the best academic institutions and industrial laboratories summarize and
synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to a wide variety
of
therapeutic opportunities. The authors review physiological resistance based on tumor architecture, cellular resistance
based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug
target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to
antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the
development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene ampli¬
fication in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin®.
Authoritative and insightful, Cancer Drug Res/stance offers basic and clinical investigators a state-of-the-art synthesis of the
many faceted research now available on the biology and genetics of tumor resistance, as well as exciting new approaches
to its prevention and eradication. |
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| language | English |
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| series2 | Cancer drug discovery and development |
| spelling | Cancer drug resistance ed. by Beverly A. Teicher Totowa, NJ Humana Press 2006 XVI, 617 S. Ill., graph. Darst. 27 cm txt rdacontent n rdamedia nc rdacarrier Cancer drug discovery and development Includes bibliographical references and index Cellules cancéreuses - Résistance aux médicaments Antineoplastic Agents therapeutic use Drug Resistance, Neoplasm Drug resistance in cancer cells Krebs Medizin (DE-588)4073781-0 gnd rswk-swf Arzneimittelresistenz (DE-588)4143180-7 gnd rswk-swf Krebs Medizin (DE-588)4073781-0 s Arzneimittelresistenz (DE-588)4143180-7 s b DE-604 Teicher, Beverly A. 1952- Sonstige (DE-588)136816886 oth Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014935806&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014935806&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Cancer drug resistance Cellules cancéreuses - Résistance aux médicaments Antineoplastic Agents therapeutic use Drug Resistance, Neoplasm Drug resistance in cancer cells Krebs Medizin (DE-588)4073781-0 gnd Arzneimittelresistenz (DE-588)4143180-7 gnd |
| subject_GND | (DE-588)4073781-0 (DE-588)4143180-7 |
| title | Cancer drug resistance |
| title_auth | Cancer drug resistance |
| title_exact_search | Cancer drug resistance |
| title_exact_search_txtP | Cancer drug resistance |
| title_full | Cancer drug resistance ed. by Beverly A. Teicher |
| title_fullStr | Cancer drug resistance ed. by Beverly A. Teicher |
| title_full_unstemmed | Cancer drug resistance ed. by Beverly A. Teicher |
| title_short | Cancer drug resistance |
| title_sort | cancer drug resistance |
| topic | Cellules cancéreuses - Résistance aux médicaments Antineoplastic Agents therapeutic use Drug Resistance, Neoplasm Drug resistance in cancer cells Krebs Medizin (DE-588)4073781-0 gnd Arzneimittelresistenz (DE-588)4143180-7 gnd |
| topic_facet | Cellules cancéreuses - Résistance aux médicaments Antineoplastic Agents therapeutic use Drug Resistance, Neoplasm Drug resistance in cancer cells Krebs Medizin Arzneimittelresistenz |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014935806&sequence=000003&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014935806&sequence=000004&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA |
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