The serotonin receptors: from molecular pharmacology to human therapeutics
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Totowa, NJ
Humana Press
2006
|
| Series: | The receptors
|
| Subjects: | |
| Online Access: | Table of contents Klappentext |
| Physical Description: | XVII, 618 S. Ill., graph. Darst. |
| ISBN: | 1588295680 9781588295682 |
Staff View
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Record in the Search Index
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| adam_text | The recent cloning and identification of a large number of serotonin (5-HT) receptors
a major family of therapeutic targets
selective 5-HT receptor agonists and antagonists for use as psychiatric, cardiovascular, and
neurological medications. In The Serotonin Receptors: From Molecular Pharmacology to
Human Therapeutics, leading experts comprehensively examine our current understanding of
the molecular and structural biology of 5-HT receptors and their pharmacological use. The
authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and
demonstrate a powerful approach to elucidating their physiological role using knockout mice
in which the 5-HT receptors were deleted. They also review our understanding of the physio¬
logical role(s) of 5-HT receptors based mainly on studies performed in genetically engineered
mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout
animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the
complexity of 5-HT receptor signal transduction.
Comprehensive and state of the art, The Serotonin Receptors: From Molecular
Pharmacology to Human Therapeutics provides an illuminating snapshot of the 5-HT recep¬
tor field today and prospects for the future, taking it from the genomic to a systems level of
understanding.
•
molecular and structural biology of 5-HT receptor signal transduction
receptors
•
level to a systems level of understanding
•
subceUalar distribution of 5-HT receptors
•
5-HT receptor knockout animals
|
| adam_txt |
The recent cloning and identification of a large number of serotonin (5-HT) receptors
a major family of therapeutic targets
selective 5-HT receptor agonists and antagonists for use as psychiatric, cardiovascular, and
neurological medications. In The Serotonin Receptors: From Molecular Pharmacology to
Human Therapeutics, leading experts comprehensively examine our current understanding of
the molecular and structural biology of 5-HT receptors and their pharmacological use. The
authors describe the anatomical, cellular, and subcellular distribution of 5-HT receptors and
demonstrate a powerful approach to elucidating their physiological role using knockout mice
in which the 5-HT receptors were deleted. They also review our understanding of the physio¬
logical role(s) of 5-HT receptors based mainly on studies performed in genetically engineered
mice. Highlights include discussions of the behavioral phenotypes of 5-HT receptor knockout
animals, the molecular biology and pharmacology of 5-HT receptors, and insights into the
complexity of 5-HT receptor signal transduction.
Comprehensive and state of the art, The Serotonin Receptors: From Molecular
Pharmacology to Human Therapeutics provides an illuminating "snapshot" of the 5-HT recep¬
tor field today and prospects for the future, taking it from the genomic to a systems level of
understanding.
•
molecular and structural biology of 5-HT receptor signal transduction
receptors
•
level to a systems level of understanding
•
subceUalar distribution of 5-HT receptors
•
5-HT receptor knockout animals |
| any_adam_object | 1 |
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| ctrlnum | (OCoLC)61859849 (DE-599)BVBBV021671351 |
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| dewey-ones | 612 - Human physiology |
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| dewey-search | 612.8/042 |
| dewey-sort | 3612.8 242 |
| dewey-tens | 610 - Medicine and health |
| discipline | Chemie / Pharmazie Biologie Medizin |
| discipline_str_mv | Chemie / Pharmazie Biologie Medizin |
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| language | English |
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| physical | XVII, 618 S. Ill., graph. Darst. |
| publishDate | 2006 |
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| series2 | The receptors |
| spelling | The serotonin receptors from molecular pharmacology to human therapeutics ed. by Bryan L. Roth Totowa, NJ Humana Press 2006 XVII, 618 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier The receptors Receptors, Serotonin physiology Receptors, Serotonin therapeutic use Serotonin Agents pharmacology Serotonin Agents therapeutic use Serotonin Physiological effect Serotonin Receptors Serotoninergic mechanisms Physiologie (DE-588)4045981-0 gnd rswk-swf Molekularpharmakologie (DE-588)4170397-2 gnd rswk-swf Serotoninrezeptor (DE-588)4181047-8 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Serotoninrezeptor (DE-588)4181047-8 s Molekularpharmakologie (DE-588)4170397-2 s Physiologie (DE-588)4045981-0 s b DE-604 Roth, Bryan L. Sonstige oth http://www.loc.gov/catdir/toc/ecip061/2005029055.html Table of contents Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014885710&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | The serotonin receptors from molecular pharmacology to human therapeutics Receptors, Serotonin physiology Receptors, Serotonin therapeutic use Serotonin Agents pharmacology Serotonin Agents therapeutic use Serotonin Physiological effect Serotonin Receptors Serotoninergic mechanisms Physiologie (DE-588)4045981-0 gnd Molekularpharmakologie (DE-588)4170397-2 gnd Serotoninrezeptor (DE-588)4181047-8 gnd |
| subject_GND | (DE-588)4045981-0 (DE-588)4170397-2 (DE-588)4181047-8 (DE-588)4143413-4 |
| title | The serotonin receptors from molecular pharmacology to human therapeutics |
| title_auth | The serotonin receptors from molecular pharmacology to human therapeutics |
| title_exact_search | The serotonin receptors from molecular pharmacology to human therapeutics |
| title_exact_search_txtP | The serotonin receptors from molecular pharmacology to human therapeutics |
| title_full | The serotonin receptors from molecular pharmacology to human therapeutics ed. by Bryan L. Roth |
| title_fullStr | The serotonin receptors from molecular pharmacology to human therapeutics ed. by Bryan L. Roth |
| title_full_unstemmed | The serotonin receptors from molecular pharmacology to human therapeutics ed. by Bryan L. Roth |
| title_short | The serotonin receptors |
| title_sort | the serotonin receptors from molecular pharmacology to human therapeutics |
| title_sub | from molecular pharmacology to human therapeutics |
| topic | Receptors, Serotonin physiology Receptors, Serotonin therapeutic use Serotonin Agents pharmacology Serotonin Agents therapeutic use Serotonin Physiological effect Serotonin Receptors Serotoninergic mechanisms Physiologie (DE-588)4045981-0 gnd Molekularpharmakologie (DE-588)4170397-2 gnd Serotoninrezeptor (DE-588)4181047-8 gnd |
| topic_facet | Receptors, Serotonin physiology Receptors, Serotonin therapeutic use Serotonin Agents pharmacology Serotonin Agents therapeutic use Serotonin Physiological effect Serotonin Receptors Serotoninergic mechanisms Physiologie Molekularpharmakologie Serotoninrezeptor Aufsatzsammlung |
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