Human virology: a text for students of medicine, dentistry, and microbiology
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Oxford [u.a.]
Oxford University Press
2006
|
| Edition: | 3. ed. |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | XVIII, 303 S. Ill., graph. Darst., Kt. |
| ISBN: | 0198566603 9780198566601 |
Staff View
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| 245 | 1 | 0 | |a Human virology |b a text for students of medicine, dentistry, and microbiology |c Leslie Collier and John Oxford ; with illustrations by Jim Pipkin |
| 250 | |a 3. ed. | ||
| 264 | 1 | |a Oxford [u.a.] |b Oxford University Press |c 2006 | |
| 300 | |a XVIII, 303 S. |b Ill., graph. Darst., Kt. | ||
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| 500 | |a Includes bibliographical references and index | ||
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| 650 | 4 | |a Virologie médicale | |
| 650 | 4 | |a Medical virology | |
| 650 | 4 | |a Virus diseases | |
| 650 | 4 | |a Virology |x methods | |
| 650 | 4 | |a Virus Diseases |x microbiology | |
| 650 | 4 | |a Virus Replication | |
| 650 | 4 | |a Viruses |x pathogenicity | |
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Record in the Search Index
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|---|---|
| adam_text | Abbreviations xvii
PARTI General principles 1
1 Virology: how it all began 3
1 Introduction 3
2 How viruses were discovered 4
3 How they were grown in the laboratory 4
4 Sizes and shapes 4
5 Replication 5
6 The control of viral diseases 5
7 Conclusions 5
2 General properties of viruses 7
1 Introduction 7
2 The architecture of viruses 8
3 Classification of viruses 14
4 The nomenclature of viruses 15
5 The range of diseases caused by viruses 15
6 Reminders 16
3 Viral replication and genetics 19
1 Introduction 19
2 The molecular biology of the mammalian cell 19
3 Virus infection and replication in a host cell 20
4 Virus assembly, release from the host cell, and maturation 26
5 Genetic variation of viruses 27
6 Reminders 27
4 How viruses cause disease 29
1 Introduction 29
2 Viral factors: pathogenicity and virulence 29
3 Interactions between viruses and host cells 30
4 The spread of viruses in the host 31
5 Patterns of disease 37
6 Shedding of virus from the host 38
7 How infectious is a virus? 38
8 Reminders 38
5 Resistance to virus infections 39
1 Introduction: innate and adaptive immunity 39
2 General factors in resistance 40
3 Local non specific defences 41
4 The adaptive immune system 43
5 T cells and cell mediated immunity 46
6 Harmful immune responses 48
7 Resistance and recovery 49
8 Reminders 49
6 Viruses and cancer in humans 51
1 Historical note 51
2 General features of viral oncogenesis 53
3 Viral oncogenes 54
4 Cellular oncogenes 55
5 Indirect mechanisms 56
6 Viruses implicated in cancers of humans 56
7 Reminders 57
7 Viruses and the community 59
1 Introduction 59
2 Definitions 59
3 What use is epidemiology? 60
4 Epidemiological methods 60
5 Serological epidemiology 61
6 Factors in the spread of viral infections 62
7 Herd immunity 63
8 Hospital acquired infections (HAIs) 65
9 The periodicity of epidemics 66
10 Control measures 67
11 Reminders 68
PART 2 Special infections 69
8 Upper respiratory tract and eye infections due to adenoviruses, coronaviruses
(including SARS CoV), and rhinoviruses 71
1 Introduction 71
2 Adenoviruses 71
3 Coronaviruses 73
4 Severe acute respiratory syndrome (SARS) 75
5 Rhinoviruses 76
6 Reminders n
9 Childhood infections caused by paramyxoviruses 79
1 Introduction 79
2 Properties of the Paramyxoviridae 79
3 Clinical and pathological aspects of paramyxovirus infections 81
4 Reminders 85
10 Orthomyxoviruses and influenza 87
1 Introduction 87
2 Properties of the orthomyxoviruses 87
3 Clinical and pathological aspects 92
4 Prevention and cure 93
5 Reminders 94
11 Gastroenteritis viruses 97
1 Introduction 97
2 Rotaviruses 97
3 Adenoviruses 100
4 Caliciviruses 100
5 Astroviruses 101
6 Laboratory diagnosis 101
7 Reminders 102
12 Rubella: postnatal infections 103
1 Introduction 103
2 Properties of the virus 103
3 Clinical and pathological aspects 103
4 Reminders 106
13 Parvoviruses 107
1 Introduction 107
2 Properties of the viruses 107
3 Clinical and pathological aspects 108
4 Reminders 109
14 Poxviruses 111
1 Introduction 111
2 Properties of the viruses 111
3 Clinical and pathological aspects of smallpox 113
4 Other poxvirus infections 117
5 Reminders 118
15 Papovaviruses 119
1 Introduction 119
2 Properties of the viruses 119
3 Clinical and pathological aspects of papillomavirus infections 121
4 Clinical and pathological aspects of polyomavirus infections 124
5 Reminders 126
16 Poliomyelitis and other picornavirus infections 127
1 Properties of the viruses 127
2 Clinical and pathological aspects 129
3 Control measures 136
4 Reminders 136
17 The herpesviruses: general properties 137
1 Classification 137
2 Morphology 137
3 Genome 138
4 Polypeptides 138
5 Antigens 138
6 Replication 139
7 Reminders 139
18 The alphaherpesviruses: herpes simplex and varicella zoster 141
1 Herpes simplexviruses 141
2 Varicella zoster virus 146
3 HerpesvirusB 147
4 Reminders 148
19 The betaherpesviruses: cytomegalovirus and human herpesviruses 6 and 7 149
1 Cytomegalovirus 149
2 Human herpesviruses types 6 and 7 151
3 Reminders 152
20 The gammaherpesviruses: Epstein Barr virus and Kaposi s
sarcoma associated herpesvirus 153
1 Epstein Barr virus 153
2 Kaposi s sarcoma associated herpesvirus (human herpesvirus 8) 156
3 Reminders 156
21 Introduction to the hepatitis viruses 159
1 Hepatitis A 160
2 Hepatitis B and deltavirus !60
3 Hepatitis C
22 The blood borne hepatitis viruses B and delta 161
1 Properties of hepatitis B virus 161
2 Clinical and pathological aspects of hepatitis B virus infections 163
3 Properties of delta virus 169
4 Clinicaland pathological aspects of hepatitis delta virus infections 170
5 Reminders 170
23 The enteric hepatitis viruses A and E 171
1 Properties of hepatitis A virus 171
2 Clinicaland pathological aspects of hepatitis A virus infections 172
3 Reminders 173
4 Properties of hepatitis E virus 173
5 Clinical and pathological aspects of hepatitis E virus infections 173
6 Reminders 173
24 The blood borne hepatitis flaviviruses 175
1 Properties of hepatitis C virus 175
2 Clinical and pathological aspects of hepatitis C virus infections 176
3 TheGBVviruses 177
4 Reminders 178
2 5 Retroviruses and Al DS 179
1 Introduction 179
2 Properties of HIV 180
3 Clinicaland pathological aspects of HIV 183
4 The discovery of the other human retroviruses: HTLV I and HTLV II 187
5 Reminders 188
26 Lyssavirus and rabies 189
1 Introduction 189
2 Properties of the virus 189
3 Clinicaland pathological aspects 190
4 Reminders 194
27 Arthropod borne viruses 195
1 Introduction 195
2 Properties of the viruses 196
3 Clinical and pathological aspects of arbovirus infections 197
4 Reminders 203
28 Exotic and dangerous infections: filoviruses, arenaviruses, and hantaviruses 205
1 Introduction 205
2 Filoviruses 206
3 Arenaviruses 208
5 Risk categories 213
6 Reminders 213
29 Prions and the spongiform encephalopathies 215
1 Prion diseases 215
2 What are prions? 217
3 Pathogenesis and pathology 218
4 Laboratory diagnosis 218
5 Safety measures 218
6 The great bovine spongiform encephalopathy outbreak 219
7 Reminders 220
PART 3 Special syndromes 221
30 Viral diseases of the central nervous system 223
1 Acute infections (Group 1) 224
2 Acute postexposure syndromes (Group 2) 226
3 Chronic infections (Group 3) 227
4 Laboratory diagnosis 227
5 Reminders 228
31 Intrauterine and perinatal infections 229
1 Pathogenesis 229
2 Fetal immunity 230
3 Specific infections 231
4 Reminders 237
32 Viral infections in patients with defective immunity 239
1 Introduction 239
2 Primary immunodeficiencies 239
3 Acquired immunodeficiencies secondary to other diseases and their treatment 241
4 Some special problems 241
5 Diagnosis and treatment 244
6 Reminders 244
33 Respiratory infections 247
34 Sexually transmitted viral infections 249
35 Resurgent and emergent viral infections 253
1 Introduction 253
2 Factors favouring the resurgence of old enemies 254
3 The emergence of new enemies 255
4 Reminders 256
PART 4 Practical aspects 257
36 The laboratory diagnosis of viral infections 259
1 Introduction 259
2 Collecting and sending clinical specimens to the laboratory 260
3 Rapid diagnostic methods 260
4 Virus isolation in cell cultures 264
5 Detection of antiviral antibodies 266
6 Reminders 267
37 Control of viral diseases by immunization 269
1 The technology and practicalities of virus vaccine production and development 269
2 Virus vaccines and public health 272
3 Passive immunization 274
4 New approaches to vaccine development 274
5 Reminders 275
38 Antiviral chemotherapy 277
1 Points of action of antivirals in the virus life cycle 277
2 The use of antivirals: general considerations 278
3 Herpes infections 280
4 Influenza 281
5 HIV infections 281
6 Interferons 283
7 The future 283
8 Reminders 284
Appendices 285
A Safety precautions: codes of practice, disinfection, and sterilization 287
1 Introduction 287
2 The clinical phase 287
3 The laboratory phase 288
4 Further reading 289
B Viral infections notifiable in the UK 291
C Suggestions for further reading 293
General virology 293
Immunology 293
Index 295
|
| adam_txt |
Abbreviations xvii
PARTI General principles 1
1 Virology: how it all began 3
1 Introduction 3
2 How viruses were discovered 4
3 How they were grown in the laboratory 4
4 Sizes and shapes 4
5 Replication 5
6 The control of viral diseases 5
7 Conclusions 5
2 General properties of viruses 7
1 Introduction 7
2 The architecture of viruses 8
3 Classification of viruses 14
4 The nomenclature of viruses 15
5 The range of diseases caused by viruses 15
6 Reminders 16
3 Viral replication and genetics 19
1 Introduction 19
2 The molecular biology of the mammalian cell 19
3 Virus infection and replication in a host cell 20
4 Virus assembly, release from the host cell, and maturation 26
5 Genetic variation of viruses 27
6 Reminders 27
4 How viruses cause disease 29
1 Introduction 29
2 Viral factors: pathogenicity and virulence 29
3 Interactions between viruses and host cells 30
4 The spread of viruses in the host 31
5 Patterns of disease 37
6 Shedding of virus from the host 38
7 How infectious is a virus? 38
8 Reminders 38
5 Resistance to virus infections 39
1 Introduction: innate and adaptive immunity 39
2 General factors in resistance 40
3 Local non specific defences 41
4 The adaptive immune system 43
5 T cells and cell mediated immunity 46
6 Harmful immune responses 48
7 Resistance and recovery 49
8 Reminders 49
6 Viruses and cancer in humans 51
1 Historical note 51
2 General features of viral oncogenesis 53
3 Viral oncogenes 54
4 Cellular oncogenes 55
5 Indirect mechanisms 56
6 Viruses implicated in cancers of humans 56
7 Reminders 57
7 Viruses and the community 59
1 Introduction 59
2 Definitions 59
3 What use is epidemiology? 60
4 Epidemiological methods 60
5 Serological epidemiology 61
6 Factors in the spread of viral infections 62
7 Herd immunity 63
8 Hospital acquired infections (HAIs) 65
9 The periodicity of epidemics 66
10 Control measures 67
11 Reminders 68
PART 2 Special infections 69
8 Upper respiratory tract and eye infections due to adenoviruses, coronaviruses
(including SARS CoV), and rhinoviruses 71
1 Introduction 71
2 Adenoviruses 71
3 Coronaviruses 73
4 Severe acute respiratory syndrome (SARS) 75
5 Rhinoviruses 76
6 Reminders n
9 Childhood infections caused by paramyxoviruses 79
1 Introduction 79
2 Properties of the Paramyxoviridae 79
3 Clinical and pathological aspects of paramyxovirus infections 81
4 Reminders 85
10 Orthomyxoviruses and influenza 87
1 Introduction 87
2 Properties of the orthomyxoviruses 87
3 Clinical and pathological aspects 92
4 Prevention and cure 93
5 Reminders 94
11 Gastroenteritis viruses 97
1 Introduction 97
2 Rotaviruses 97
3 Adenoviruses 100
4 Caliciviruses 100
5 Astroviruses 101
6 Laboratory diagnosis 101
7 Reminders 102
12 Rubella: postnatal infections 103
1 Introduction 103
2 Properties of the virus 103
3 Clinical and pathological aspects 103
4 Reminders 106
13 Parvoviruses 107
1 Introduction 107
2 Properties of the viruses 107
3 Clinical and pathological aspects 108
4 Reminders 109
14 Poxviruses 111
1 Introduction 111
2 Properties of the viruses 111
3 Clinical and pathological aspects of smallpox 113
4 Other poxvirus infections 117
5 Reminders 118
15 Papovaviruses 119
1 Introduction 119
2 Properties of the viruses 119
3 Clinical and pathological aspects of papillomavirus infections 121
4 Clinical and pathological aspects of polyomavirus infections 124
5 Reminders 126
16 Poliomyelitis and other picornavirus infections 127
1 Properties of the viruses 127
2 Clinical and pathological aspects 129
3 Control measures 136
4 Reminders 136
17 The herpesviruses: general properties 137
1 Classification 137
2 Morphology 137
3 Genome 138
4 Polypeptides 138
5 Antigens 138
6 Replication 139
7 Reminders 139
18 The alphaherpesviruses: herpes simplex and varicella zoster 141
1 Herpes simplexviruses 141
2 Varicella zoster virus 146
3 HerpesvirusB 147
4 Reminders 148
19 The betaherpesviruses: cytomegalovirus and human herpesviruses 6 and 7 149
1 Cytomegalovirus 149
2 Human herpesviruses types 6 and 7 151
3 Reminders 152
20 The gammaherpesviruses: Epstein Barr virus and Kaposi's
sarcoma associated herpesvirus 153
1 Epstein Barr virus 153
2 Kaposi's sarcoma associated herpesvirus (human herpesvirus 8) 156
3 Reminders 156
21 Introduction to the hepatitis viruses 159
1 Hepatitis A 160
2 Hepatitis B and deltavirus !60
3 Hepatitis C
22 The blood borne hepatitis viruses B and delta 161
1 Properties of hepatitis B virus 161
2 Clinical and pathological aspects of hepatitis B virus infections 163
3 Properties of delta virus 169
4 Clinicaland pathological aspects of hepatitis delta virus infections 170
5 Reminders 170
23 The enteric hepatitis viruses A and E 171
1 Properties of hepatitis A virus 171
2 Clinicaland pathological aspects of hepatitis A virus infections 172
3 Reminders 173
4 Properties of hepatitis E virus 173
5 Clinical and pathological aspects of hepatitis E virus infections 173
6 Reminders 173
24 The blood borne hepatitis flaviviruses 175
1 Properties of hepatitis C virus 175
2 Clinical and pathological aspects of hepatitis C virus infections 176
3 TheGBVviruses 177
4 Reminders 178
2 5 Retroviruses and Al DS 179
1 Introduction 179
2 Properties of HIV 180
3 Clinicaland pathological aspects of HIV 183
4 The discovery of the other human retroviruses: HTLV I and HTLV II 187
5 Reminders 188
26 Lyssavirus and rabies 189
1 Introduction 189
2 Properties of the virus 189
3 Clinicaland pathological aspects 190
4 Reminders 194
27 Arthropod borne viruses 195
1 Introduction 195
2 Properties of the viruses 196
3 Clinical and pathological aspects of arbovirus infections 197
4 Reminders 203
28 Exotic and dangerous infections: filoviruses, arenaviruses, and hantaviruses 205
1 Introduction 205
2 Filoviruses 206
3 Arenaviruses 208
5 Risk categories 213
6 Reminders 213
29 Prions and the spongiform encephalopathies 215
1 Prion diseases 215
2 What are prions? 217
3 Pathogenesis and pathology 218
4 Laboratory diagnosis 218
5 Safety measures 218
6 The great bovine spongiform encephalopathy outbreak 219
7 Reminders 220
PART 3 Special syndromes 221
30 Viral diseases of the central nervous system 223
1 Acute infections (Group 1) 224
2 Acute postexposure syndromes (Group 2) 226
3 Chronic infections (Group 3) 227
4 Laboratory diagnosis 227
5 Reminders 228
31 Intrauterine and perinatal infections 229
1 Pathogenesis 229
2 Fetal immunity 230
3 Specific infections 231
4 Reminders 237
32 Viral infections in patients with defective immunity 239
1 Introduction 239
2 Primary immunodeficiencies 239
3 Acquired immunodeficiencies secondary to other diseases and their treatment 241
4 Some special problems 241
5 Diagnosis and treatment 244
6 Reminders 244
33 Respiratory infections 247
34 Sexually transmitted viral infections 249
35 Resurgent and emergent viral infections 253
1 Introduction 253
2 Factors favouring the resurgence of old enemies 254
3 The emergence of new enemies 255
4 Reminders 256
PART 4 Practical aspects 257
36 The laboratory diagnosis of viral infections 259
1 Introduction 259
2 Collecting and sending clinical specimens to the laboratory 260
3 Rapid diagnostic methods 260
4 Virus isolation in cell cultures 264
5 Detection of antiviral antibodies 266
6 Reminders 267
37 Control of viral diseases by immunization 269
1 The technology and practicalities of virus vaccine production and development 269
2 Virus vaccines and public health 272
3 Passive immunization 274
4 New approaches to vaccine development 274
5 Reminders 275
38 Antiviral chemotherapy 277
1 Points of action of antivirals in the virus life cycle 277
2 The use of antivirals: general considerations 278
3 Herpes infections 280
4 Influenza 281
5 HIV infections 281
6 Interferons 283
7 The future 283
8 Reminders 284
Appendices 285
A Safety precautions: codes of practice, disinfection, and sterilization 287
1 Introduction 287
2 The clinical phase 287
3 The laboratory phase 288
4 Further reading 289
B Viral infections notifiable in the UK 291
C Suggestions for further reading 293
General virology 293
Immunology 293
Index 295 |
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| index_date | 2024-07-02T14:40:27Z |
| indexdate | 2024-07-09T20:39:03Z |
| institution | BVB |
| isbn | 0198566603 9780198566601 |
| language | English |
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| publishDateSort | 2006 |
| publisher | Oxford University Press |
| record_format | marc |
| spelling | Collier, Leslie H. Verfasser aut Human virology a text for students of medicine, dentistry, and microbiology Leslie Collier and John Oxford ; with illustrations by Jim Pipkin 3. ed. Oxford [u.a.] Oxford University Press 2006 XVIII, 303 S. Ill., graph. Darst., Kt. txt rdacontent n rdamedia nc rdacarrier Includes bibliographical references and index Maladies à virus Virologie médicale Medical virology Virus diseases Virology methods Virus Diseases microbiology Virus Replication Viruses pathogenicity Virologie (DE-588)4063597-1 gnd rswk-swf (DE-588)4151278-9 Einführung gnd-content Virologie (DE-588)4063597-1 s DE-604 Oxford, John S. Verfasser aut HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014792885&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Collier, Leslie H. Oxford, John S. Human virology a text for students of medicine, dentistry, and microbiology Maladies à virus Virologie médicale Medical virology Virus diseases Virology methods Virus Diseases microbiology Virus Replication Viruses pathogenicity Virologie (DE-588)4063597-1 gnd |
| subject_GND | (DE-588)4063597-1 (DE-588)4151278-9 |
| title | Human virology a text for students of medicine, dentistry, and microbiology |
| title_auth | Human virology a text for students of medicine, dentistry, and microbiology |
| title_exact_search | Human virology a text for students of medicine, dentistry, and microbiology |
| title_exact_search_txtP | Human virology a text for students of medicine, dentistry, and microbiology |
| title_full | Human virology a text for students of medicine, dentistry, and microbiology Leslie Collier and John Oxford ; with illustrations by Jim Pipkin |
| title_fullStr | Human virology a text for students of medicine, dentistry, and microbiology Leslie Collier and John Oxford ; with illustrations by Jim Pipkin |
| title_full_unstemmed | Human virology a text for students of medicine, dentistry, and microbiology Leslie Collier and John Oxford ; with illustrations by Jim Pipkin |
| title_short | Human virology |
| title_sort | human virology a text for students of medicine dentistry and microbiology |
| title_sub | a text for students of medicine, dentistry, and microbiology |
| topic | Maladies à virus Virologie médicale Medical virology Virus diseases Virology methods Virus Diseases microbiology Virus Replication Viruses pathogenicity Virologie (DE-588)4063597-1 gnd |
| topic_facet | Maladies à virus Virologie médicale Medical virology Virus diseases Virology methods Virus Diseases microbiology Virus Replication Viruses pathogenicity Virologie Einführung |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014792885&sequence=000004&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT collierleslieh humanvirologyatextforstudentsofmedicinedentistryandmicrobiology AT oxfordjohns humanvirologyatextforstudentsofmedicinedentistryandmicrobiology |