Infection and inflammation: impacts on oncogenesis ; 5 tables
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Basel [u.a.]
Karger
2006
|
| Series: | Contributions to microbiology
13 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis Klappentext |
| Physical Description: | X, 246 S. Ill., graph. Darst. |
| ISBN: | 3805580649 |
Staff View
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Record in the Search Index
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| adam_text | Contents
VII In
Schmidt, A. (Widen)
IX Foreword
Dittmar,
General Aspects
1
Aspects of Inflammation, Infection and
Schmidt, A. (Witten); Weber, O.F. (Bonn)
16
Duesberg, P.; Li, R. (Berkeley, Calif.); Fabarius, A.;
45
Theory of Carcinogenesis: Role of Inflammation on the
Promotion of Initiated Stem Cells
Trosko, J.E.;
Specific Pathogens
66
Leung, W.K. (Hong Kong)
81
Yosry, A. (Cairo)
101 Relevant Oncogenic
Original Pathogens and Animal Models for Human Disease
Truyen, U. (Leipzig);
Infection, Inflammation and
118
Its Impact on Cancer Development
de Visser,
138
A Consequence of Tumor Cell Fusion?
Pawelek, J.; Chakraborty, A.; Lazova, R.; Yilmaz, Y.; Cooper, D.;
Brash, D. (New Haven, Conn.); Handerson, T. (Worchester, Mass.)
156
Dittmar,
Chemokine-Directed Metastasis
170
Gomperts, B.N.; Strieter, R.M. (Los Angeles, Calif.)
191
Zlotnik, A. (San Diego, Calif.)
200
Heyder, C; Gloria-Maercker, E.; Hatzmann,W.; Zaenker, K.S.; Dittmar, T.
209
Helms, M.W. (Muenster); Brandt, B.H. (Hamburg); Contag, C.H. (Stanford, Calif.)
Outlook and Perspectives
232
Challenge
Zaenker, K.S.
240
241
Contents VI
10
Editor: H. Herwald, Lund
VIII
11
A Challenge for Science, Medicine and the Public Health System
2nd,
Editors: H.F. Rabenau, J. Cinatl, H.W. Doerr, Frankfurt/Main
XII
12
Editors: W. Russell, H. Herwald, Lund
VIII
13
Editors: T. Dittmar, K.S. Zaenker, A. Schmidt, Witten
X
The last two decades have shown that the local microenvironment plays a pivotal role
in cancer progression. Cancer is not the result of mutation events in single cells, but of
a complex interplay of tumor cells, inflammatory cells, stem cells, growth factors, cyto-
kines, chemokines and DNA-damaging agents.
This book provides an up-to-date overview of how infections and chronic inflammatory
conditions can give rise to the onset of a malignant phenotype, a theory that was origi¬
nally postulated by Rudolf Virchow as early as
discuss novel aspects such as the role of stem cells and the occurrence of aneuploidy in
carcinogenesis. Several examples of pathogens and their correlation with specific cancer
types are described, e.g. Helkobacter pylori and gastric
and bladder cancer. The mechanisms of carcinogenesis are examined in detail as are the
types of cells that can transform to a malignant phenotype, with special emphasis on
stem cells which have recently been shown to give rise to cancer. Further chapters dis¬
cuss the role of chemokines in directing metastasis and describe options for visualizing
metastasis formation in 3-dimensional model systems and in the living body.
Our increasing knowledge of the inflammatory microenvironment s role in the carci¬
nogenic process will be the basis for investigating new anti-inflammatory strategies to
counter tumor formation and growth. Therefore, this book is essential reading for sci¬
entists and clinicians working in cancer research and prevention.
|
| adam_txt |
Contents
VII In
Schmidt, A. (Widen)
IX Foreword
Dittmar,
General Aspects
1
Aspects of Inflammation, Infection and
Schmidt, A. (Witten); Weber, O.F. (Bonn)
16
Duesberg, P.; Li, R. (Berkeley, Calif.); Fabarius, A.;
45
Theory of Carcinogenesis: Role of Inflammation on the
Promotion of Initiated Stem Cells
Trosko, J.E.;
Specific Pathogens
66
Leung, W.K. (Hong Kong)
81
Yosry, A. (Cairo)
101 Relevant Oncogenic
Original Pathogens and Animal Models for Human Disease
Truyen, U. (Leipzig);
Infection, Inflammation and
118
Its Impact on Cancer Development
de Visser,
138
A Consequence of Tumor Cell Fusion?
Pawelek, J.; Chakraborty, A.; Lazova, R.; Yilmaz, Y.; Cooper, D.;
Brash, D. (New Haven, Conn.); Handerson, T. (Worchester, Mass.)
156
Dittmar,
Chemokine-Directed Metastasis
170
Gomperts, B.N.; Strieter, R.M. (Los Angeles, Calif.)
191
Zlotnik, A. (San Diego, Calif.)
200
Heyder, C; Gloria-Maercker, E.; Hatzmann,W.; Zaenker, K.S.; Dittmar, T.
209
Helms, M.W. (Muenster); Brandt, B.H. (Hamburg); Contag, C.H. (Stanford, Calif.)
Outlook and Perspectives
232
Challenge
Zaenker, K.S.
240
241
Contents VI
10
Editor: H. Herwald, Lund
VIII
11
A Challenge for Science, Medicine and the Public Health System
2nd,
Editors: H.F. Rabenau, J. Cinatl, H.W. Doerr, Frankfurt/Main
XII
12
Editors: W. Russell, H. Herwald, Lund
VIII
13
Editors: T. Dittmar, K.S. Zaenker, A. Schmidt, Witten
X
The last two decades have shown that the local microenvironment plays a pivotal role
in cancer progression. Cancer is not the result of mutation events in single cells, but of
a complex interplay of tumor cells, inflammatory cells, stem cells, growth factors, cyto-
kines, chemokines and DNA-damaging agents.
This book provides an up-to-date overview of how infections and chronic inflammatory
conditions can give rise to the onset of a malignant phenotype, a theory that was origi¬
nally postulated by Rudolf Virchow as early as
discuss novel aspects such as the role of stem cells and the occurrence of aneuploidy in
carcinogenesis. Several examples of pathogens and their correlation with specific cancer
types are described, e.g. Helkobacter pylori and gastric
and bladder cancer. The mechanisms of carcinogenesis are examined in detail as are the
types of cells that can transform to a malignant phenotype, with special emphasis on
stem cells which have recently been shown to give rise to cancer. Further chapters dis¬
cuss the role of chemokines in directing metastasis and describe options for visualizing
metastasis formation in 3-dimensional model systems and in the living body.
Our increasing knowledge of the inflammatory microenvironment's role in the carci¬
nogenic process will be the basis for investigating new anti-inflammatory strategies to
counter tumor formation and growth. Therefore, this book is essential reading for sci¬
entists and clinicians working in cancer research and prevention. |
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| language | English |
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| series | Contributions to microbiology |
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| spelling | Infection and inflammation impacts on oncogenesis ; 5 tables vol. eds. Thomas Dittmar ... Basel [u.a.] Karger 2006 X, 246 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Contributions to microbiology 13 Entzündung (DE-588)4014975-4 gnd rswk-swf Carcinogenese (DE-588)4069853-1 gnd rswk-swf Infektion (DE-588)4161650-9 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Carcinogenese (DE-588)4069853-1 s Infektion (DE-588)4161650-9 s Entzündung (DE-588)4014975-4 s DE-604 Dittmar, Thomas Sonstige oth Contributions to microbiology 13 (DE-604)BV012190851 13 Digitalisierung UBRegensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014778719&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014778719&sequence=000002&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Infection and inflammation impacts on oncogenesis ; 5 tables Contributions to microbiology Entzündung (DE-588)4014975-4 gnd Carcinogenese (DE-588)4069853-1 gnd Infektion (DE-588)4161650-9 gnd |
| subject_GND | (DE-588)4014975-4 (DE-588)4069853-1 (DE-588)4161650-9 (DE-588)4143413-4 |
| title | Infection and inflammation impacts on oncogenesis ; 5 tables |
| title_auth | Infection and inflammation impacts on oncogenesis ; 5 tables |
| title_exact_search | Infection and inflammation impacts on oncogenesis ; 5 tables |
| title_exact_search_txtP | Infection and inflammation impacts on oncogenesis ; 5 tables |
| title_full | Infection and inflammation impacts on oncogenesis ; 5 tables vol. eds. Thomas Dittmar ... |
| title_fullStr | Infection and inflammation impacts on oncogenesis ; 5 tables vol. eds. Thomas Dittmar ... |
| title_full_unstemmed | Infection and inflammation impacts on oncogenesis ; 5 tables vol. eds. Thomas Dittmar ... |
| title_short | Infection and inflammation |
| title_sort | infection and inflammation impacts on oncogenesis 5 tables |
| title_sub | impacts on oncogenesis ; 5 tables |
| topic | Entzündung (DE-588)4014975-4 gnd Carcinogenese (DE-588)4069853-1 gnd Infektion (DE-588)4161650-9 gnd |
| topic_facet | Entzündung Carcinogenese Infektion Aufsatzsammlung |
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| volume_link | (DE-604)BV012190851 |
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