DNA microarrays and related genomics techniques: design, analysis, and interpretation of experiments
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Boca Raton [u.a.]
Chapman & Hall/CRC
2006
|
| Series: | Biostatistics
15 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | 371 S. Ill., graph. Darst. 25 cm |
| ISBN: | 0824754611 9780824754617 |
Staff View
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| adam_text | Contents
Chapter 1
Microarray Platforms 1
Patrick M. Gaffney and Kathy L. Moser
Chapter 2
Normalization of Microarray Data 9
Rudolph S. Parrish and Robert R. Delongchamp
Chapter 3
Microarray Quality Control and Assessment 29
David Finkelstein, Michael Janis, Alan Williams, Kathryn Steiger, and
Jacques Retief
Chapter 4
Epistemological Foundations of Statistical Methods for High Dimensional
Biology 57
Stanislav O. Zakharkin, Tapan Mehta, Murat Tanik, and David B. Allison
Chapter 5
The Role of Sample Size on Measures of Uncertainty and Power 77
Gary L. Gadbury, Qinfang Xiang, Jode W. Edwards, Grier P. Page, and
David B. Allison
Chapter 6
Pooling Biological Samples in Microarray Experiments 95
Christina M. Kendziorski
Chapter 7
Designing Microarrays for the Analysis of Gene Expressions Ill
Jane Y. Chang and Jason C. Hsu
Chapter 8
Overview of Standard Clustering Approaches for Gene Microarray Data
Analysis 131
Elizabeth Garrett Mayer
Chapter 9
Cluster Stability 159
Bernard S. Gorman and Kui Zhang
Chapter 10
Dimensionality Reduction and Discrimination 177
Jeanne Kowalski and Then Zhang
Chapter 11
Modeling Affymetrix Data at the Probe Level 197
Tzu Ming Chu, ShibingDeng, and Russell D. Wolftnger
Chapter 12
Parametric Linear Models 223
Christopher S. Coffey and Stacey S. Cofield
Chapter 13
The Use of Nonparametric Procedures in the Statistical Analysis of
Microarray Data 245
T. Mark Beasley, Jacob PL. Brand, and Jeffrey D. Long
Chapter 14
Bayesian Analysis of Microarray Data 267
Jode W. Edwards andPulak Ghosh
Chapter 15
False Discovery Rate and Multiple Comparison Procedures 289
Chiara Sabatti
Chapter 16
Using Standards to Facilitate Interoperation of Heterogeneous Microarray
Databases and Analytic Tools 305
Kei Hoi Cheung
Chapter 17
Postanalysis Interpretation: What Do I Do with This Gene List? 321
Michael V. Osier
Chapter 18
Combining High Dimensional Biological Data to Study Complex Diseases
and Quantitative Traits 335
Grier P. Page and Douglas M. Ruden
Index 361
1 Microarray Platforms ^M
Patrick M. Gaffney and Kathy L Moser ^^H
CONTENTS ^^|
1.1 Introduction 1 ^^^^H
1.2 Microarray Technology 1 ^^^^H
1.3 Autoantigen and Cytokine Microarrays 2 ^^^^|
1.4 DNA and Oligonucleotide Microarrays 4 ^^^^|
1.5 Tiling Arrays 4 ^^^^H
1.6 DataAnalysis 5 ^^^^|
1.7 Future Directions 5 ^^^^|
References 6 i ^^^^H
1.1 INTRODUCTION ^^H
As with the development of any novel and potentially powerful technology, the ^^^^H
prospect of revealing new information that may dramatically change our under ^^^^|
standing of biological processes can generate much excitement. Such is true for the ^^^^fl
emerging genomic approaches that make possible high density assays using micro ^^^^|
array platforms. Indeed, it is difficult, if not impossible, to imagine any area of biology ^^^^|
that could not be affected by the wide range of potential applications of microarray ^^^^|
technology. Numerous examples, such as those from the field of oncology, provide ^^^^H
striking evidence of the power of microarrays to bring about extraordinary advances in ^^^^H
molecularly defining important disease phenotypes that were otherwise unrecognized ^^^^H
using conventional approaches such as histology. ^^^^H
In this chapter, we present a general overview of microarray platforms currently ^^^^H
in use with particular emphasis on high density DNA arrays. We touch briefly on ^^^^|
approaches to data analysis leaving most of the details for the ensuing chapters. For ^^^^H
those just entering the microarray arena or interested in more details, a series of ^^^^H
particularly useful reviews have recently been published that take stock of the latest ^^^^H
developments and discuss the most pressing challenges of this technology [1]. ^^^^|
1.2 MICROARRAY TECHNOLOGY ^^H
Microarray technology provides an unprecedented and uniquely comprehensive probe ^^^^H
into the coordinated workings of entire biological pathways and genomic level ^^^^fl
1 ^^^H
|
| adam_txt |
Contents
Chapter 1
Microarray Platforms 1
Patrick M. Gaffney and Kathy L. Moser
Chapter 2
Normalization of Microarray Data 9
Rudolph S. Parrish and Robert R. Delongchamp
Chapter 3
Microarray Quality Control and Assessment 29
David Finkelstein, Michael Janis, Alan Williams, Kathryn Steiger, and
Jacques Retief
Chapter 4
Epistemological Foundations of Statistical Methods for High Dimensional
Biology 57
Stanislav O. Zakharkin, Tapan Mehta, Murat Tanik, and David B. Allison
Chapter 5
The Role of Sample Size on Measures of Uncertainty and Power 77
Gary L. Gadbury, Qinfang Xiang, Jode W. Edwards, Grier P. Page, and
David B. Allison
Chapter 6
Pooling Biological Samples in Microarray Experiments 95
Christina M. Kendziorski
Chapter 7
Designing Microarrays for the Analysis of Gene Expressions Ill
Jane Y. Chang and Jason C. Hsu
Chapter 8
Overview of Standard Clustering Approaches for Gene Microarray Data
Analysis 131
Elizabeth Garrett Mayer
Chapter 9
Cluster Stability 159
Bernard S. Gorman and Kui Zhang
Chapter 10
Dimensionality Reduction and Discrimination 177
Jeanne Kowalski and Then Zhang
Chapter 11
Modeling Affymetrix Data at the Probe Level 197
Tzu Ming Chu, ShibingDeng, and Russell D. Wolftnger
Chapter 12
Parametric Linear Models 223
Christopher S. Coffey and Stacey S. Cofield
Chapter 13
The Use of Nonparametric Procedures in the Statistical Analysis of
Microarray Data 245
T. Mark Beasley, Jacob PL. Brand, and Jeffrey D. Long
Chapter 14
Bayesian Analysis of Microarray Data 267
Jode W. Edwards andPulak Ghosh
Chapter 15
False Discovery Rate and Multiple Comparison Procedures 289
Chiara Sabatti
Chapter 16
Using Standards to Facilitate Interoperation of Heterogeneous Microarray
Databases and Analytic Tools 305
Kei Hoi Cheung
Chapter 17
Postanalysis Interpretation: "What Do I Do with This Gene List?" 321
Michael V. Osier
Chapter 18
Combining High Dimensional Biological Data to Study Complex Diseases
and Quantitative Traits 335
Grier P. Page and Douglas M. Ruden
Index 361
1 Microarray Platforms ^M
Patrick M. Gaffney and Kathy L Moser ^^H
CONTENTS ^^|
1.1 Introduction 1 ^^^^H
1.2 Microarray Technology 1 ^^^^H
1.3 Autoantigen and Cytokine Microarrays 2 ^^^^|
1.4 DNA and Oligonucleotide Microarrays 4 ^^^^|
1.5 Tiling Arrays 4 ^^^^H
1.6 DataAnalysis 5 ^^^^|
1.7 Future Directions 5 ^^^^|
References 6 i ^^^^H
1.1 INTRODUCTION \ ^^H
As with the development of any novel and potentially powerful technology, the ^^^^H
prospect of revealing new information that may dramatically change our under ^^^^|
standing of biological processes can generate much excitement. Such is true for the ^^^^fl
emerging genomic approaches that make possible high density assays using micro ^^^^|
array platforms. Indeed, it is difficult, if not impossible, to imagine any area of biology ^^^^|
that could not be affected by the wide range of potential applications of microarray ^^^^|
technology. Numerous examples, such as those from the field of oncology, provide ^^^^H
striking evidence of the power of microarrays to bring about extraordinary advances in ^^^^H
molecularly defining important disease phenotypes that were otherwise unrecognized ^^^^H
using conventional approaches such as histology. ^^^^H
In this chapter, we present a general overview of microarray platforms currently ^^^^H
in use with particular emphasis on high density DNA arrays. We touch briefly on ^^^^|
approaches to data analysis leaving most of the details for the ensuing chapters. For ^^^^H
those just entering the microarray arena or interested in more details, a series of ^^^^H
particularly useful reviews have recently been published that take stock of the latest ^^^^H
developments and discuss the most pressing challenges of this technology [1]. ^^^^|
1.2 MICROARRAY TECHNOLOGY ^^H
Microarray technology provides an unprecedented and uniquely comprehensive probe ^^^^H
into the coordinated workings of entire biological pathways and genomic level ^^^^fl
1 ^^^H |
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| spelling | DNA microarrays and related genomics techniques design, analysis, and interpretation of experiments ed. by David B. Allison ... Boca Raton [u.a.] Chapman & Hall/CRC 2006 371 S. Ill., graph. Darst. 25 cm txt rdacontent n rdamedia nc rdacarrier Biostatistics 15 Includes bibliographical references and index Dna larpcal Genomas larpcal Puces à ADN DNA microarrays Datenanalyse (DE-588)4123037-1 gnd rswk-swf DNS-Chip (DE-588)4721796-0 gnd rswk-swf Methode (DE-588)4038971-6 gnd rswk-swf Biostatistik (DE-588)4729990-3 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content DNS-Chip (DE-588)4721796-0 s Methode (DE-588)4038971-6 s DE-604 Datenanalyse (DE-588)4123037-1 s Biostatistik (DE-588)4729990-3 s Allison, David B. Sonstige oth Biostatistics 15 (DE-604)BV013101415 15 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014738582&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | DNA microarrays and related genomics techniques design, analysis, and interpretation of experiments Biostatistics Dna larpcal Genomas larpcal Puces à ADN DNA microarrays Datenanalyse (DE-588)4123037-1 gnd DNS-Chip (DE-588)4721796-0 gnd Methode (DE-588)4038971-6 gnd Biostatistik (DE-588)4729990-3 gnd |
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| title | DNA microarrays and related genomics techniques design, analysis, and interpretation of experiments |
| title_auth | DNA microarrays and related genomics techniques design, analysis, and interpretation of experiments |
| title_exact_search | DNA microarrays and related genomics techniques design, analysis, and interpretation of experiments |
| title_exact_search_txtP | DNA microarrays and related genomics techniques design, analysis, and interpretation of experiments |
| title_full | DNA microarrays and related genomics techniques design, analysis, and interpretation of experiments ed. by David B. Allison ... |
| title_fullStr | DNA microarrays and related genomics techniques design, analysis, and interpretation of experiments ed. by David B. Allison ... |
| title_full_unstemmed | DNA microarrays and related genomics techniques design, analysis, and interpretation of experiments ed. by David B. Allison ... |
| title_short | DNA microarrays and related genomics techniques |
| title_sort | dna microarrays and related genomics techniques design analysis and interpretation of experiments |
| title_sub | design, analysis, and interpretation of experiments |
| topic | Dna larpcal Genomas larpcal Puces à ADN DNA microarrays Datenanalyse (DE-588)4123037-1 gnd DNS-Chip (DE-588)4721796-0 gnd Methode (DE-588)4038971-6 gnd Biostatistik (DE-588)4729990-3 gnd |
| topic_facet | Dna Genomas Puces à ADN DNA microarrays Datenanalyse DNS-Chip Methode Biostatistik Aufsatzsammlung |
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