Bioinformatics and drug discovery:
Gespeichert in:
| Format: | Buch |
|---|---|
| Sprache: | English |
| Veröffentlicht: |
Totowa, NJ
Humana Press
2006
|
| Schriftenreihe: | Methods in molecular biology
316 |
| Schlagworte: | |
| Online-Zugang: | Inhaltsverzeichnis Klappentext |
| Beschreibung: | Includes bibliographical references and index |
| Beschreibung: | X, 444 S. Ill., graph. Darst. 24 cm |
| ISBN: | 1588293467 |
Internformat
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| 245 | 1 | 0 | |a Bioinformatics and drug discovery |c ed. by Richard S. Larson |
| 264 | 1 | |a Totowa, NJ |b Humana Press |c 2006 | |
| 300 | |a X, 444 S. |b Ill., graph. Darst. |c 24 cm | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 1 | |a Methods in molecular biology |v 316 | |
| 500 | |a Includes bibliographical references and index | ||
| 650 | 4 | |a Bio-informatique | |
| 650 | 4 | |a Chimie combinatoire | |
| 650 | 4 | |a Criblage à haut débit (Développement des médicaments) | |
| 650 | 4 | |a Médicaments - Développement | |
| 650 | 4 | |a Drug development | |
| 650 | 4 | |a Bioinformatics | |
| 650 | 4 | |a High throughput screening (Drug development) | |
| 650 | 4 | |a Combinatorial chemistry | |
| 650 | 4 | |a Drug Design | |
| 650 | 4 | |a Computational Biology |x methods | |
| 650 | 4 | |a Drug Evaluation, Preclinical | |
| 650 | 4 | |a Genetic Techniques | |
| 650 | 4 | |a Microarray Analysis | |
| 650 | 4 | |a Pharmacogenetics |x methods | |
| 650 | 0 | 7 | |a Bioinformatik |0 (DE-588)4611085-9 |2 gnd |9 rswk-swf |
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Datensatz im Suchindex
| _version_ | 1804135094275801088 |
|---|---|
| adam_text | Contents
Preface
Contributors
1
Eliot H. Ohlstein, Anthony G. Johnson, John D. Elliot,
and Anne M. Romanic
2
Scott A. Ness
3
Analysis of
Xiwei Wu and T. Gregory
4
Siqun Wang and Qiong Cheng
5
in Functional Cenomics
Francisco Azuaje, Fatima Al-Shahrour, and
6
James O. Mclnerney, Caroline S. Finnerty, Jennifer M. Commins,
and Gayle K. Philip
7
Casey S. Husser, Jeffrey R.
Amnon Shabo, Steven H. Brown, Karen E. Lee,
and Peter L Elkin
8
and Pharmacogenomics
Omer
9
Suma
10
Protein Kinases: Combining
Spin Labeling for Nuclear Magnetic Resonance Dectection
of
Thomas K. Harris
11
for Drug Discovery
Laurel O. Sillerud and Richard S. Larson
vii
viii Contents
12
Darren R. Flower
13
Bassil I. Dahiyat
14
or Virtual Screening
Cristian
15
From
Alexis S.
Alexander V. Dubanov, and Vladlen S. Skvortsov
Index
Many of the new technologies that are transforming drug discovery require a high degree of inter¬
disciplinary expertise in physical science, life science, and computer science for bioinformatic analysis of
their output. In Bioinformatics and Drug Discovery, a panel of researchers from academic and pharmaceu¬
tical laboratories describes readily reproducible bioinformatic methods to advance the drug discovery
process from gene identification to protein modeling to the identification of specific drug candidates. The
authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug
targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situ¬
ations. Because these technologies are still emergent, each chapter contains an extended introduction that
explains the theory and application of the technology and techniques described. The protocols follow the
successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions,
an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents,
and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and highly practical, Bioinformatics and Drug Discovery makes it possible to apply in
the research laboratory the powerful new technologies that promise to greatly improve and speed up the
discovery of new drugs.
ItMtRls
Review of cutting-edge
techniques used in drug discovery
Btoinfomutic techniques used in microarray
analysis
Virtual screening and in silico protein design for
identification of drug candidates
Chapter introductions that explain the theory and
application of each technology
Step-by-step instructions to ensure successful results
Tricks of the trade and notes on troubleshooting and
avoiding known pitfalls
|
| adam_txt |
Contents
Preface
Contributors
1
Eliot H. Ohlstein, Anthony G. Johnson, John D. Elliot,
and Anne M. Romanic
2
Scott A. Ness
3
Analysis of
Xiwei Wu and T. Gregory
4
Siqun Wang and Qiong Cheng
5
in Functional Cenomics
Francisco Azuaje, Fatima Al-Shahrour, and
6
James O. Mclnerney, Caroline S. Finnerty, Jennifer M. Commins,
and Gayle K. Philip
7
Casey S. Husser, Jeffrey R.
Amnon Shabo, Steven H. Brown, Karen E. Lee,
and Peter L Elkin
8
and Pharmacogenomics
Omer
9
Suma
10
Protein Kinases: Combining
Spin Labeling for Nuclear Magnetic Resonance Dectection
of
Thomas K. Harris
11
for Drug Discovery
Laurel O. Sillerud and Richard S. Larson
vii
viii Contents
12
Darren R. Flower
13
Bassil I. Dahiyat
14
or Virtual Screening
Cristian
15
From
Alexis S.
Alexander V. Dubanov, and Vladlen S. Skvortsov
Index
Many of the new technologies that are transforming drug discovery require a high degree of inter¬
disciplinary expertise in physical science, life science, and computer science for bioinformatic analysis of
their output. In Bioinformatics and Drug Discovery, a panel of researchers from academic and pharmaceu¬
tical laboratories describes readily reproducible bioinformatic methods to advance the drug discovery
process from gene identification to protein modeling to the identification of specific drug candidates. The
authors demonstrate these techniques, including microarray analysis, the analysis of genes as potential drug
targets, virtual screening and in silico protein design, and cheminformatics, in a variety of practical situ¬
ations. Because these technologies are still emergent, each chapter contains an extended introduction that
explains the theory and application of the technology and techniques described. The protocols follow the
successful Methods in Molecular Biology™ series format, each offering step-by-step laboratory instructions,
an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents,
and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and highly practical, Bioinformatics and Drug Discovery makes it possible to apply in
the research laboratory the powerful new technologies that promise to greatly improve and speed up the
discovery of new drugs.
ItMtRls
Review of cutting-edge
techniques used in drug discovery
Btoinfomutic techniques used in microarray
analysis
Virtual screening and in silico protein design for
identification of drug candidates
Chapter introductions that explain the theory and
application of each technology
Step-by-step instructions to ensure successful results
Tricks of the trade and notes on troubleshooting and
avoiding known pitfalls |
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| index_date | 2024-07-02T13:51:49Z |
| indexdate | 2024-07-09T20:35:02Z |
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| language | English |
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| publisher | Humana Press |
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| series | Methods in molecular biology |
| series2 | Methods in molecular biology |
| spelling | Bioinformatics and drug discovery ed. by Richard S. Larson Totowa, NJ Humana Press 2006 X, 444 S. Ill., graph. Darst. 24 cm txt rdacontent n rdamedia nc rdacarrier Methods in molecular biology 316 Includes bibliographical references and index Bio-informatique Chimie combinatoire Criblage à haut débit (Développement des médicaments) Médicaments - Développement Drug development Bioinformatics High throughput screening (Drug development) Combinatorial chemistry Drug Design Computational Biology methods Drug Evaluation, Preclinical Genetic Techniques Microarray Analysis Pharmacogenetics methods Bioinformatik (DE-588)4611085-9 gnd rswk-swf Arzneimittelentwicklung (DE-588)4143176-5 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Bioinformatik (DE-588)4611085-9 s Arzneimittelentwicklung (DE-588)4143176-5 s b DE-604 Larson, Richard S. Sonstige oth Methods in molecular biology 316 (DE-604)BV035362695 316 Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014618772&sequence=000009&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis Digitalisierung UB Regensburg application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=014618772&sequence=000010&line_number=0002&func_code=DB_RECORDS&service_type=MEDIA Klappentext |
| spellingShingle | Bioinformatics and drug discovery Methods in molecular biology Bio-informatique Chimie combinatoire Criblage à haut débit (Développement des médicaments) Médicaments - Développement Drug development Bioinformatics High throughput screening (Drug development) Combinatorial chemistry Drug Design Computational Biology methods Drug Evaluation, Preclinical Genetic Techniques Microarray Analysis Pharmacogenetics methods Bioinformatik (DE-588)4611085-9 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| subject_GND | (DE-588)4611085-9 (DE-588)4143176-5 (DE-588)4143413-4 |
| title | Bioinformatics and drug discovery |
| title_auth | Bioinformatics and drug discovery |
| title_exact_search | Bioinformatics and drug discovery |
| title_exact_search_txtP | Bioinformatics and drug discovery |
| title_full | Bioinformatics and drug discovery ed. by Richard S. Larson |
| title_fullStr | Bioinformatics and drug discovery ed. by Richard S. Larson |
| title_full_unstemmed | Bioinformatics and drug discovery ed. by Richard S. Larson |
| title_short | Bioinformatics and drug discovery |
| title_sort | bioinformatics and drug discovery |
| topic | Bio-informatique Chimie combinatoire Criblage à haut débit (Développement des médicaments) Médicaments - Développement Drug development Bioinformatics High throughput screening (Drug development) Combinatorial chemistry Drug Design Computational Biology methods Drug Evaluation, Preclinical Genetic Techniques Microarray Analysis Pharmacogenetics methods Bioinformatik (DE-588)4611085-9 gnd Arzneimittelentwicklung (DE-588)4143176-5 gnd |
| topic_facet | Bio-informatique Chimie combinatoire Criblage à haut débit (Développement des médicaments) Médicaments - Développement Drug development Bioinformatics High throughput screening (Drug development) Combinatorial chemistry Drug Design Computational Biology methods Drug Evaluation, Preclinical Genetic Techniques Microarray Analysis Pharmacogenetics methods Bioinformatik Arzneimittelentwicklung Aufsatzsammlung |
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