Multidisciplinary approach to lung cancer:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Philadelphia [u.a.]
Saunders
2005
|
| Series: | Hematology, oncology clinics of North America
19,2 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XII S., S. 209 - 426 Ill., graph. Darst. |
| ISBN: | 1416027734 |
Staff View
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| 650 | 4 | |a Lungs |x Cancer | |
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| adam_text | CONTENTS
Preface xi
Gregory A. Masters
Lung Cancer Screening 209
Thomas Bauer
It has been demonstrated that 85% of all lung cancers are associ¬
ated with previous or current smoking. A group of patients has
been identified that is at a higher risk for lung cancer, stroke, and
heart disease. This article reviews previous reports, current con¬
sensus statements, problems that are associated with current
screening programs, and hopes for the future.
Clinical Evaluation and Staging of Patients Who Have
Lung Cancer 219
Thomas A. Hensing
This article updates the performance characteristics of the most
commonly used diagnostic and staging modalities in the evalua¬
tion of a patient who has lung cancer. Recent data with newer
modalities, like positron emission tomography, are reviewed, and
their role in this evaluation is discussed.
Nonsurgical Therapy of Stages I and II Non Small Cell
Lung Cancer 237
Quynh Thu Le and David W. Petrik
For patients who have stages I and II non small cell lung cancer
(NSCLC) and who are unable or unwilling to undergo surgical
resection, nonsurgical treatment modalities have been used with
curative intent. Conventionally fractionated radiotherapy has been
VOLUME 19 • NUMBER 2 . APRIL 2005 v
the mainstay of nonsurgical therapy; however, advances in technol¬
ogy and the clinical application of radiobiologic principles have
allowed more accurately targeted treatment that delivers higher
effective doses to the tumor, while respecting the tolerance of
surrounding normal tissues. This article discusses nonsurgical
approaches to the treatment of early stage NSCLC, including several
promising techniques, such as radiation dose escalation, altered
radiation fractionation, stereotactic radiotherapy, and radiofre
quency ablation.
Adjuvant Chemotherapy of Lung Cancer: Methodologic
Issues and Therapeutic Advances 263
Gary M. Strauss
This article discusses methodologic issues relevant to the interpre¬
tation of recent studies focusing on adjuvant chemotherapy of lung
cancer. It also attempts to conclude where we currently stand in
this field.
Postoperative Radiation Therapy for Patients Who Have
Resected Non Small Cell Lung Cancer 283
Henry Wagner, Jr
The role of adjuvant postoperative therapy for patients who have
resected non small cell lung cancer (NSCLC) has been controver¬
sial. Recent large trials and meta analysis support a modest, but
significant, survival benefit for postoperative adjuvant chemother¬
apy. Postoperative radiation therapy has little potential benefit
in patients who have No or Nj disease and should not be used
routinely in these patients. There are suggestions of benefit for
patients who have N2 disease, but adequately powered trials have
not been conducted to demonstrate a possible small, but clinically
worthwhile, survival benefit in this subgroup. Central nervous
system relapse has emerged as an increasing problem for patients
who have NSCLC; trials of prophylactic cranial irradiation are
underway in several cooperative trial groups.
The Role of Surgery in Stage IIIA Non Small Cell
Lung Cancer 303
Wilfried E.E. Eberhardt, Rodrigo Hepp, and Georgios Stamatis
For most patients who have stage III non small cell lung cancer
(NSCLC), a combination of chemotherapy and radiation repre¬
sents the current treatment of choice. Recent developments
include the use of adjuvant chemotherapy after up front surgery
in subgroups of patients who have stage III disease, as well as
vi CONTENTS
innovative ways to deliver concurrent chemoradiotherapy or
combinations of chemotherapy with higher dose conformal
radiotherapy techniques. This article focuses on patients who
have stage IIIA NSCLC and reviews the different possibilities for
their treatment. Special emphasis is given to the inclusion of
surgery into the different approaches to this disease stage. The
current literature on this topic is reviewed, and the different
aspects of surgical treatment in the management of stage IIIA
NSCLC are discussed.
Combined Chemoradiotherapy in Small Cell Lung Cancer 321
Noah M. Hahn and Nasser Hanna
Combined chemoradiotherapy is the established standard of care for
limited stage small cell lung cancer; it provides cure in 15% to 25% of
patients. Early concurrent therapy imparts a 5% long term survival
benefit compared with sequential therapy. Hyperfractionated deliv¬
ery of radiotherapy may provide a small incremental benefit when
compared with standard fractionation. Radiotherapy dose escalation
and reduced radiotherapy volumes are feasible; however, survival
benefit has not been confirmed. Cisplatin and etoposide remain the
preferred chemotherapy agents. New chemotherapeutic agents and
novel treatment approaches are under intense investigation.
Novel Therapies in Lung Cancer 343
Olwen Hahn and Ravi Salgia
This article reviews novel therapies that are under development
for non small cell lung cancer and small cell lung cancer.
Supportive Care in Lung Cancer 369
Michelle Boyar and Harry Raftopoulos
Lung cancer often is associated with significant morbidity,
which has a detrimental effect on quality of life. Supportive care
plays a central role in the multimodal treatment of lung cancer.
Palliation of symptoms often improves quality of life and com¬
pliance with therapy. New developments in supportive care,
reviewed here, include management of symptoms of the disease,
such as respiratory problems, pain, and cachexia, as well as
effects of treatment, including chemotherapy induced nausea
and vomiting, neutropenia, anemia, and mucositis. In the past
few years, significant advances have been made in this field;
however, palliation of the symptoms of lung cancer remains an
area of active investigation.
CONTENTS vii
Quality of Life in Lung Cancer: The Validity and
Cross Cultural Applicability of the Functional Assessment
of Cancer Therapy Lung Scale 389
Zeeshan Butt, Kimberly Webster, Amy R. Eisenstein,
Jennifer Beaumont, David Eton, Gregory A. Masters,
and David Cella
This article discusses the validity and cross cultural applicability
of the Functional Assessment of Cancer Therapy Lung scale, a
self report instrument that measures multidimensional quality
of life.
Index 421
viii CONTENTS
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| physical | XII S., S. 209 - 426 Ill., graph. Darst. |
| publishDate | 2005 |
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| publisher | Saunders |
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| series | Hematology, oncology clinics of North America |
| series2 | Hematology, oncology clinics of North America |
| spelling | Multidisciplinary approach to lung cancer guest ed. Gregory A. Masters Philadelphia [u.a.] Saunders 2005 XII S., S. 209 - 426 Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Hematology, oncology clinics of North America 19,2 Hematologie gtt Interdisciplinaire samenwerking gtt Longkanker gtt Oncologie gtt Carcinoma, Non-Small-Cell Lung Carcinoma, Small Cell Lung Neoplasms Lungs Cancer Lungs Tumors Quality of Life Lungenkrebs (DE-588)4036668-6 gnd rswk-swf (DE-588)4143413-4 Aufsatzsammlung gnd-content Lungenkrebs (DE-588)4036668-6 s b DE-604 Masters, Gregory A. Sonstige (DE-588)1037136373 oth Hematology, oncology clinics of North America 19,2 (DE-604)BV000625446 19,2 HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=013144060&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Multidisciplinary approach to lung cancer Hematology, oncology clinics of North America Hematologie gtt Interdisciplinaire samenwerking gtt Longkanker gtt Oncologie gtt Carcinoma, Non-Small-Cell Lung Carcinoma, Small Cell Lung Neoplasms Lungs Cancer Lungs Tumors Quality of Life Lungenkrebs (DE-588)4036668-6 gnd |
| subject_GND | (DE-588)4036668-6 (DE-588)4143413-4 |
| title | Multidisciplinary approach to lung cancer |
| title_auth | Multidisciplinary approach to lung cancer |
| title_exact_search | Multidisciplinary approach to lung cancer |
| title_full | Multidisciplinary approach to lung cancer guest ed. Gregory A. Masters |
| title_fullStr | Multidisciplinary approach to lung cancer guest ed. Gregory A. Masters |
| title_full_unstemmed | Multidisciplinary approach to lung cancer guest ed. Gregory A. Masters |
| title_short | Multidisciplinary approach to lung cancer |
| title_sort | multidisciplinary approach to lung cancer |
| topic | Hematologie gtt Interdisciplinaire samenwerking gtt Longkanker gtt Oncologie gtt Carcinoma, Non-Small-Cell Lung Carcinoma, Small Cell Lung Neoplasms Lungs Cancer Lungs Tumors Quality of Life Lungenkrebs (DE-588)4036668-6 gnd |
| topic_facet | Hematologie Interdisciplinaire samenwerking Longkanker Oncologie Carcinoma, Non-Small-Cell Lung Carcinoma, Small Cell Lung Neoplasms Lungs Cancer Lungs Tumors Quality of Life Lungenkrebs Aufsatzsammlung |
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