Case studies in biomedical research ethics:
Saved in:
| Main Author: | |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Cambridge, Mass. [u.a.]
MIT Press
2004
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| Series: | Basic bioethics
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| Subjects: | |
| Online Access: | Table of contents Inhaltsverzeichnis |
| Item Description: | Includes bibliographical references and index |
| Physical Description: | xvii, 340 p. 26 cm |
| ISBN: | 9780262134378 0262632861 9780262632867 0262134373 |
Staff View
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| 245 | 1 | 0 | |a Case studies in biomedical research ethics |c Timothy F. Murphy |
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| 300 | |a xvii, 340 p. |c 26 cm | ||
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| 650 | 4 | |a Éthique médicale - Recherche - Cas, Études de | |
| 650 | 4 | |a Ethik | |
| 650 | 4 | |a Medical ethics |v Case studies | |
| 650 | 4 | |a Bioethics |v Case studies | |
| 650 | 4 | |a Medical ethics |x Research |v Case studies | |
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Contents
Series Foreword vii
Acknowledgments ix
Preface xi
Cases by Chapter xiii
Introduction 1
1 Oversight and Study Design 13
2 Informed Consent 53
3 Selection of Subjects 91
4 Conflicts of Interest 127
5 Social Effects of Research 153
6 Embryos, Fetuses, and Children 193
7 Genetic Research 221
8 Use of Animals 249
9 Authorship and Publication 273
Appendix A: The Nuremberg Code 307
Appendix B: The Declaration of Helsinki 309
Glossary 315
Cases by General Category 319
Alphabetical List of Cases 327
Index 333
Cases by Chapter
1 Oversight and Study Design 13
1.1 The Tuskegee Syphilis Studies 21
1.2 Desperate Measures 23
1.3 Surgical Innovation and Research 25
1.4 Artificial Hearts: The Need for Review 26
1.5 Access to Nonapproved Drugs 28
1.6 Off Label Use of Drugs 30
1.7 When Does Research Begin? 31
1.8 Surrogate End Points in Research 32
1.9 Sham Surgical Procedures 33
1.10 Placebos and Neural Tube Defects 34
1.11 Anonymous HIV Research 35
1.12 Surgical Treatment of Short Bowel Syndrome 37
1.13 Trial Design: Prerandomization 38
1.14 Research Involving Illegal Abortions 40
1.15 Interim Review of Research 42
1.16 Suing the Institutional Review Board 43
1.17 Journalism as Research 45
1.18 Equipoise in Clinical Research 47
1.19 Children and Lead Dust in Their Environment 49
1.20 Death in a Lung Physiology Study 51
2 Informed Consent 53
2.1 Research on People about to Die 59
2.2 Waived Consent in a Breast Cancer Trial 61
2.3 Informed Consent: Emergency Treatment 63
2.4 Deferred Consent to Emergency Experimentation 64
2.5 Research Directives 66
2.6 Military Exemptions from Informed Consent 67
2.7 Radiation Experiments 69
2.8 Yellow Fever Experiments 71
2.9 Exposure of Australian Soldiers to Malaria 73
2.10 Obedience to Authority 75
2.11 Tearoom Trade 77
2.12 Court Ordered Research Participation 79
2.13 Reanimated Organs for Transplantation 80
2.14 Marketing Research 82
2.15 Pasteur's Rabies Experiments 83
2.16 Community Consent 85
2.17 Community Advisory Boards 87
2.18 Subjects with Psychiatric Disorders 89
2.19 Disclosure of IRB Review and Approval 90
3 Selection of Subjects 91
3.1 Hemodialysis as Experimental Medicine: The God Committee 98
3.2 Children as Research Subjects 100
3.3 The Patient Physician Relationship in Research 101
3.4 Malaria Experiments on Prisoners 102
3.5 Prisoners as Research Subjects 104
3.6 Spouse Consent to Research Participation 105
3.7 Is There a Duty to Serve as a Research Subject? 106
3.8 Live Cancer Cell Injections 108
3.9 Self Experimentation: The Peruvian Medical Student Hero 110
3.10 Self Experimentation: Cancerous Tissue 112
3.11 Self Experimentation: AIDS Vaccine 114
3.12 Radiation Studies: Tracer Studies in Children 115
3.13 Is Stuttering Innate or Learned? 117
3.14 Perinatal HIV Transmission Studies 119
3.15 Payment for Research Subjects 121
3.16 Involvement of Poor and Wealthy Subjects 123
3.17 Inclusion of Pregnant Women in Clinical Trials 124
4 Conflicts of Interest 127
4.1 The John Moore Case 132
4.2 Compensation for Biological Materials 134
4.3 Payments to Physicians for Enrolling Research Subjects 136
4.4 Conflict of Interest: Divesting Financial Interest 137
4.5 Research on the Maltreatment of Children 138
4.6 Artificial Hearts: How Many Tries? 140
4.7 Conflict of Interest: Institutional Financial Gain 142
4.8 Independence and Sponsorship of IRBs 143
4.9 Capitation Fees for Research Subjects 144
4.10 Research Universities for Hire? 145
4.11 The Function of IRBs 147
4.12 For Profit IRBs 148
4.13 Willowbrook Hepatitis Studies 149
4.14 Conflict of Interest in HIV Prevention Studies 151
5 Social Effects of Research 153
5.1 Cloning for Longer Life 159
5.2 Sexual Orientation Research 161
5.3 Genetic Research and Forced Choices 163
5.4 Earth's Population 165
5.5 Heart Transplants: Racial Politics 166
5.6 Contracts with Research Subjects 167
5.7 Compensation for Research Injuries 169
5.8 Nude Posture Photographs 171
5.9 Disclosure of Study Results 173
5.10 Research Funded by Taxpayers 175
5.11 Priorities in Health Care: The Aged and Their Diseases 176
5.12 Curbing the Methuselah Vote 178
5.13 The End of a Marriage 180
5.14 Rationing Health Care for Centenarians 182
5.15 Offshore Rejuvenation 184
5.16 Reading Your Mind 185
5.17 US Recruitment of Nazi Researchers 186
5.18 When the Subject Is Afraid of the Researcher 188
5.19 Abative Research 190
5.20 Drugs for the Diseases of the Poor 191
6 Embryos, Fetuses, and Children 193
6.1 Antipregnancy Vaccine 200
6.2 Pregnant Men 202
6.3 Political Compromise on Stem Cell Research 203
6.4 No Embryonic Stem Cell Research 206
6.5 Research on Human Embryos 208
6.6 Access to Reproductive Cloning 209
6.7 Obtaining Fetal Tissue for Research 210
6.8 Fetal Death and Tissue for Research 211
6.9 Freezing and Transplanting Ovary Tissue 212
6.10 Placebos in Research with Children 214
6.11 Designer Children ? 216
6.12 What Counts as Disease? 217
6.13 Deaf Culture and Babies 218
6.14 SmartKid 219
7 Genetic Research 221
7.1 Asilomar 227
7.2 Germ Line Therapy 228
7.3 ELSI Projects 230
7.4 Environmental Genome Research 232
7.5 The Specter of Eugenics 233
7.6 Secondhand Smoke 234
7.7 Patented Organisms 235
7.8 Therapy versus Enhancement 236
7.9 Consent and Assumption of Risk in Genetic Therapy 237
7.10 Genetic Warfare 239
7.11 Gene Transfer and the Children of Same Sex Couples 240
7.12 One Baby, Three Parents: Germ Line Modification of Children 241
7.13 Genetic Screening and Prenatal Diagnostics 242
7.14 Adolescents and Genetic Testing 244
7.15 "Franken Food" 246
8 Use of Animals 249
8.1 Animal Entrapment 253
8.2 The Study of Animal Aggression 254
8.3 Baboon Head Injury Experiments 255
8.4 Animal to Human Xenografts 257
8.5 Kitten Experiments 259
8.6 Depriving Primates of Mothers 260
8.7 The Green Fluorescent Rabbit 261
8.8 Animal Vivisection 262
8.9 Primate Language Acquisition 264
8.10 Whale Research 265
8.11 Public Access to Animal Research Review Committees 266
8.12 Saving the Florida Panther 267
8.13 Expanding the Animal Welfare Act 269
8.14 Cloning Pets 271
9 Authorship and Publication 273
9.1 The Order of Authors' Names 279
9.2 Authorship 281
9.3 Reporting Scientific Advances 283
9.4 Origins of Fraud 285
9.5 Repetitive Publication 286
9.6 When Industry Does Not Like Published Findings 287
9.7 Embargoes of Scientific Reports 289
9.8 Medical Advertising 291
9.9 When a Subject Recognizes Himself in a Scientific Report 292
9.10 Graduate Students as Authors 294
9.11 A Question of Theft? 296
9.12 Responsibility for Data 297
I
9.13 From Class Report to Formal Study 298
9.14 Matching Punishment to Misconduct 300
9.15 Use of Nazi Data: Pernkopf's Atlas 301
9.16 Use of Nazi Data: Hypothermia Studies 302
9.17 Graduate School Blues 304 |
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| spelling | Murphy, Timothy F. Verfasser aut Case studies in biomedical research ethics Timothy F. Murphy Cambridge, Mass. [u.a.] MIT Press 2004 xvii, 340 p. 26 cm txt rdacontent n rdamedia nc rdacarrier Basic bioethics Includes bibliographical references and index Bioéthique - Cas, Études de Bioéthique - Recherche - Cas, Études de Ethische aspecten gtt Medische ethiek gtt Onderzoek gtt Éthique médicale - Cas, Études de Éthique médicale - Recherche - Cas, Études de Ethik Medical ethics Case studies Bioethics Case studies Medical ethics Research Case studies Bioethics Research Case studies Medizinische Ethik (DE-588)4074672-0 gnd rswk-swf Forschung (DE-588)4017894-8 gnd rswk-swf Bioethik (DE-588)4006791-9 gnd rswk-swf (DE-588)4522595-3 Fallstudiensammlung gnd-content Medizinische Ethik (DE-588)4074672-0 s DE-604 Bioethik (DE-588)4006791-9 s Forschung (DE-588)4017894-8 s http://www.loc.gov/catdir/toc/fy051/2003060799.html Table of contents HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=013016102&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Murphy, Timothy F. Case studies in biomedical research ethics Bioéthique - Cas, Études de Bioéthique - Recherche - Cas, Études de Ethische aspecten gtt Medische ethiek gtt Onderzoek gtt Éthique médicale - Cas, Études de Éthique médicale - Recherche - Cas, Études de Ethik Medical ethics Case studies Bioethics Case studies Medical ethics Research Case studies Bioethics Research Case studies Medizinische Ethik (DE-588)4074672-0 gnd Forschung (DE-588)4017894-8 gnd Bioethik (DE-588)4006791-9 gnd |
| subject_GND | (DE-588)4074672-0 (DE-588)4017894-8 (DE-588)4006791-9 (DE-588)4522595-3 |
| title | Case studies in biomedical research ethics |
| title_auth | Case studies in biomedical research ethics |
| title_exact_search | Case studies in biomedical research ethics |
| title_full | Case studies in biomedical research ethics Timothy F. Murphy |
| title_fullStr | Case studies in biomedical research ethics Timothy F. Murphy |
| title_full_unstemmed | Case studies in biomedical research ethics Timothy F. Murphy |
| title_short | Case studies in biomedical research ethics |
| title_sort | case studies in biomedical research ethics |
| topic | Bioéthique - Cas, Études de Bioéthique - Recherche - Cas, Études de Ethische aspecten gtt Medische ethiek gtt Onderzoek gtt Éthique médicale - Cas, Études de Éthique médicale - Recherche - Cas, Études de Ethik Medical ethics Case studies Bioethics Case studies Medical ethics Research Case studies Bioethics Research Case studies Medizinische Ethik (DE-588)4074672-0 gnd Forschung (DE-588)4017894-8 gnd Bioethik (DE-588)4006791-9 gnd |
| topic_facet | Bioéthique - Cas, Études de Bioéthique - Recherche - Cas, Études de Ethische aspecten Medische ethiek Onderzoek Éthique médicale - Cas, Études de Éthique médicale - Recherche - Cas, Études de Ethik Medical ethics Case studies Bioethics Case studies Medical ethics Research Case studies Bioethics Research Case studies Medizinische Ethik Forschung Bioethik Fallstudiensammlung |
| url | http://www.loc.gov/catdir/toc/fy051/2003060799.html http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=013016102&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| work_keys_str_mv | AT murphytimothyf casestudiesinbiomedicalresearchethics |