Ciba Foundation Symposium on Chemistry and Biology of Pteridines:
Saved in:
| Corporate Author: | |
|---|---|
| Format: | Conference Proceeding Book |
| Language: | English |
| Published: |
London
Churchill
1954
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| Series: | Ciba Foundation symposia
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| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Physical Description: | XIV, 425 S. Ill., zahlr. graph. Darst. |
Staff View
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| 111 | 2 | |a Symposium on Chemistry and Biology of Pteridines |d 1954 |c London |j Verfasser |0 (DE-588)5525914-5 |4 aut | |
| 245 | 1 | 0 | |a Ciba Foundation Symposium on Chemistry and Biology of Pteridines |c ed. G. E. W. Wolstenholme ... |
| 246 | 1 | 3 | |a Chemistry and biology of pteridines |
| 264 | 1 | |a London |b Churchill |c 1954 | |
| 300 | |a XIV, 425 S. |b Ill., zahlr. graph. Darst. | ||
| 336 | |b txt |2 rdacontent | ||
| 337 | |b n |2 rdamedia | ||
| 338 | |b nc |2 rdacarrier | ||
| 490 | 0 | |a Ciba Foundation symposia | |
| 650 | 4 | |a Pteridines | |
| 655 | 7 | |0 (DE-588)1071861417 |a Konferenzschrift |2 gnd-content | |
| 700 | 1 | |a Wolstenholme, Gordon E. W. |d 1913-2004 |e Sonstige |0 (DE-588)121827496 |4 oth | |
| 710 | 2 | |a Ciba Foundation |e Sonstige |0 (DE-588)1003913-2 |4 oth | |
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Record in the Search Index
| _version_ | 1804132708385816576 |
|---|---|
| adam_text | CIBA FOUNDATION SYMPOSIUM
! ON
I
HEMISTRY AND BIOLOGY
OF PTERIDINES
1 Editors for the Ciba Foundation
GEW WOLSTENHOLME, OBE,MA,MB,B Ch
j and
1 MARGARET P CAMERON, MA,ABLS
i
With 143 Illustrations and Diagrams
LONDON
J amp;A CHURCHILL, LTD
104 GLOUCESTER PLAGE ^Wri __
Car! Oosri Heiii
Frank urt/Mclrl
[ ; CONTENTS
! i! PAGE
Chairman s opening remarks
PROF A ALBERT, DSC, PHDMED, ERIC (Dept of Medical
Chemistry, Australian National University, London) 1
Part I—Chemistry
Chairman: PROF A ALBERT
Ring-opening reactions of pteridines
jEC TAYLOR, JR , PIID (William Albert Noyes Laboratory,
University of Illinois, Urbana; now at Princeton University,
Princeton,NJ)2
The alkylation of pteridines
!HCS WOOD, PHD (Dept of Chemistry, Royal Technical
College, Glasgow) So
DISCUSSION: Albert, Bergel, Brown, Cosulich, Druey, Elion,
Hitchings, Jacobson, Korte, Mason, Taylor, Timmis,
Tschesche,Wood,Woods42
M:
The reduction and reoxidation of some 8-substituted
pteridines
(! GERTRUDE B ELION, MS (Wellcome Research Laboratories,
I Tuckahoe,NY)49
•I
DISCUSSION: Albert, Bergel, Busnel, Cosulich, Elion, Forrest,
Taylor, Tschesche, Wood 58
The monosubstituted pteridines
jDJ BROWN, PHD (Dept of Medical Chemistry, Australian
j National University, London) 62
I
DISCUSSION: Albert, Bergel, Brown, Busnel, Collier, Druey,
Elion, Korte, Taylor, Tschesche 71
Some aspects of the ultraviolet absorption spectra of the
pteridines
I jS; F MASON, DPhil (Dept of Medical Chemistry, Australian
iNationalUniversity,London)74
DISCUSSION: Albert, Elion, Korte, Mason, Taylor, Wood 91
viii CONTENTS
The use of o-aminonitroso compounds in the synthesis of
pteridines and some analogous ring-systems
G M TIMMIS, MSC, FRIC, DGI FELTON, DPhii and T S
OSDENE, BSc (Chester Beatty Researcli Institute, London)
DISCUSSION: Albert, Bergel, Haddow, Jacobson, Timmis, Wolf
Recent developments in pteridine synthesis
E C TAYLOR, Jit , PHD (now at Princeton University), with
J A CARBON, USE, R B GARLAND, BSC, D R HOFF, BSC,
C F HOWELL, BSC and W R SHERMAN, BSC (William Albert
Noyes Laboratory, University of Illinois, Urbana)
DISCUSSION: Albert Bergel, Forrest, Hitchings, Korte, Polonov-
ski,Taylor,Timmis,Tschesche,Wood
Chromatographic and electrophoretic studies of pteridines
M POLONOVSKJ, MD, PhD, H JEROME, MD and P GONNARD
(Laboratoire de Biochimie de la Faculty de Medccine de
Paris)
DISCUSSION: Albert, Busnel, Collier, Forrest, Korte, Polonovski,
Tschesche
The constitution of urothione
PROF DR R TSCHESCHE (Biochem Abteilung, Chem
Staatsinstitut,Hamburg)
DISCUSSION: Albert, Bergel, Busnel, Coates, Collier, Hitchings,
Jacobson, Korte, Polonovski, Taylor, Tschesche, Woods
The pteridines of Drosophila melanogaster
H S FORRES T, PhD and H K MITCHELL, PhD (Division of
Biology, California Institute of Technology, Pasadena)
DISCUSSION: Albert, Bellairs, Busnel, Cosulich, Elion, Forrest,
Jacobson, Korte, Mason, Polonovski, Taylor, Tschesche,
Wood
The constitution of fluorescyanine
Doz DR F KORTE (Biochem Abteilung, Chem Staats
institut,Hamburg)
New observations on fluorescyanine B
M POLONOVSKI, MD, PhD, R-G BUSNEL, IR DR (now at Lab
de Physiol Aooustique, Jouy-en-Josas), H JEROME, MD and
M MARTINET, MD (Laboratoire de Biochimie de la Faculty de
M6decine,Paris)
DISCUSSION: Albert, Bergel, Busnel, Elion, Forrest, Jacobson,
Korte,Polonovski,Taylor,Tschesche
CONTENTS IX
PAGE
Sulphonamide derivatives of pteridines
M J FAHHENBACH, phi), K H COLLINS, BS, M E HULTQUIST,
PhD and J M SMITH, JR , PhD Presented by Donna B
COSULICH, PHD (American Cyanamid Co , Bound Brook,
NJ) 173
DISCUSSION: Albert, Bergel, Collier, Cosulich, Elion, Jacobson,
Mason, Taylor, Tschesche, Woods • 179
Some dipyrimidopyrazines (pyrimidopteridin es)
ELVIRA A FALCO, MS and G H HITCHINGS, PHD (Wellcome
Research Laboratories, Tuckahoe, NY) 183
Structural studies on pyrimidopteridines The structure of
bisalloxazine and diuracilpyridazine
E C TAYLOR, JR , PhD (now at Princeton University), with
C K CAIN, PKD and H M Loux, BSC (William Albert Noyes
Laboratory, University of Illinois, Urbana) ^ 193
DISCUSSION: Albert, Haddow, Hitchings, Jacobson, Taylor,
Timmis201
Some unresolved problems
A ALBERT, DSc, PhDMci, FRIC (Dept of Medical Chemistry,
Australian National University, London) 204
|j DISCUSSION: Albert, Bergel, Elion, Korte, Mason, Nimmo-Smith,
] Taylor, Timmis, Wolf, Wood 216
t
j Part II—Biological aspects
j : Chairman: DR W JACOBSON
j
j Metabolic relations between ^-aminobenzoic acid and folic
acid in micro-organisms
!DD WOODS, PUD, FHS (Microbiology Unit, Dept of Bio-
j chemistry, Oxford) 220
The function of folic acid in the biosynthesis of purine and
pyrimidine derivatives
JRH NIMMO-SMITH, I Phii, MB, chB (Microbiology Unit,
Dept of Biochemistry, Oxford) 237
DISCUSSION: Albert, Cosulich, Elion, Girdwood, Hitchings,
Jacobson, Kidder, Nimmo-Smith, Tschesche, Woods 249
X CONTENTS
PAGE
The effects of folic acid analogues on the growth and cell
division of micro-organisms
M WEBB, nri: (Strangeways Research Lab , Cambridge) 253
DISCUSSION: Albert, Collier, Cosulich, Elion, Hitchings, Hutchi
son, Jacobson, Kidder Taylor, Webb, Woods 269
Antimetabolic and antimicrobial properties of certain
2:4- diaminopteridines
HOJ COLLIER, PHD (Research Division, Allen amp; Hanburys
Ltd , Ware, Herts ) 272
DISCUSSION: Collier Girdwood, Hitchings, Hutchison 287
Derivatives of condensed pyrimidine systems as anti
metabolites
G H HITCHINGS, phn, GERTRUDE B ELION, MS and S
SINGER, MS (Wellcome Research Laboratories, Tuckahoe,
NY)290
DISCUSSION: Albert, Bergel, Collier, Colsky, Elion, Haddow,
Hitchings, Hutchison, Jacobson, Kidder, Nimmo-Smith,
Taylor, Tschesche, Woods 300
The biological activity of folic acid and certain substituted
pteridines for Tetralt/imena
G W KIDDER, PHD (Dept of Biology, Amherst College,
Amherst, Mass ) 304
DISCUSSION: Albert, Collier, Colsky, Cosulich, Elion, Hitchings,
Kidder, Korte Woods 312
The yellow pigment of the argentaffine cells of the mam
malian gastro-intestinal tract
W JACOBSON, am, PhD (Strangeways Research Laboratory,
Cambridge) 314
DISCUSSION: Albert, Busnel, Cosulich, Elion, Girdwood,
Haddow, Jacobson 327
The mode of action of folic acid antagonists and the func
tion of the Leuconostoc citrovorum factor
W JACOBSON, MD, PhD (Strangeways Research Laboratory,
Cambridge) 329
DISCUSSION: Albert, Bergel, Collier, Colsky, Cosulich, Elion,
Forrest, Girdwood, Hutchison, Jacobson, Kidder, Mason,
Nimmo-Smith Taylor, Tschesche, Webb, Woods 351
CONTENTS
PAGE
The effects of folic acid antagonists on embryonic develop
ment
RUTH BELLAIRS, PHD (Dept of Anatomy, University College,
London; now at Dept of Zoology and Comparative Anatomy,
St Bartholomew s Medical College, London) 356
DISCUSSION: Bellairs, Bergel, Hitchings, Jacobson, Kidder 364
Studies on pteridine metabolism
DORRIS J HUTCHISON, PhD and J H BURCHENAL, MD
(Memorial Center for Cancer and Allied Diseases, New York,
NY) 366
DISCUSSION: Colsky, Girdwood, Hitchings, Hutchison, Jacob-
son, Kidder, Nimmo-Smith, Timmis, Woods 380
Some aspects of disordered folic acid metabolism in man
R H GIRDWOOD, MB, CHB, PhD, FRCP ECI, MRCP (Dept of
Medicine, Edinburgh University) 385
DISCUSSION: Bergel, Busnel, Coates, Collier, Colsky, Gird wood,
Jacobson, Kidder, Nimmo-Smith 405
Occurrence of hepatic fibrosis in children with acute
leukaemia treated with folic acid antagonists
J COLSKY, MD (Medical Services, Maimonides Hospital of
Brooklyn, NY) 407
DISCUSSION: Colsky, Timmis 413
Chairman s closing remarks
W JACOBSON, MD, phu (Strangeways Research Laboratory,
Cambridge) 414
|
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| author_corporate | Symposium on Chemistry and Biology of Pteridines London |
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| author_facet | Symposium on Chemistry and Biology of Pteridines London |
| author_sort | Symposium on Chemistry and Biology of Pteridines London |
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| bvnumber | BV019300419 |
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| ctrlnum | (OCoLC)9054227 (DE-599)BVBBV019300419 |
| dewey-full | 547.7 |
| dewey-hundreds | 500 - Natural sciences and mathematics |
| dewey-ones | 547 - Organic chemistry |
| dewey-raw | 547.7 |
| dewey-search | 547.7 |
| dewey-sort | 3547.7 |
| dewey-tens | 540 - Chemistry and allied sciences |
| discipline | Chemie / Pharmazie |
| format | Conference Proceeding Book |
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| genre | (DE-588)1071861417 Konferenzschrift gnd-content |
| genre_facet | Konferenzschrift |
| id | DE-604.BV019300419 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:57:07Z |
| institution | BVB |
| institution_GND | (DE-588)5525914-5 (DE-588)1003913-2 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-012768686 |
| oclc_num | 9054227 |
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| owner | DE-19 DE-BY-UBM DE-188 |
| owner_facet | DE-19 DE-BY-UBM DE-188 |
| physical | XIV, 425 S. Ill., zahlr. graph. Darst. |
| publishDate | 1954 |
| publishDateSearch | 1954 |
| publishDateSort | 1954 |
| publisher | Churchill |
| record_format | marc |
| series2 | Ciba Foundation symposia |
| spelling | Symposium on Chemistry and Biology of Pteridines 1954 London Verfasser (DE-588)5525914-5 aut Ciba Foundation Symposium on Chemistry and Biology of Pteridines ed. G. E. W. Wolstenholme ... Chemistry and biology of pteridines London Churchill 1954 XIV, 425 S. Ill., zahlr. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Ciba Foundation symposia Pteridines (DE-588)1071861417 Konferenzschrift gnd-content Wolstenholme, Gordon E. W. 1913-2004 Sonstige (DE-588)121827496 oth Ciba Foundation Sonstige (DE-588)1003913-2 oth HEBIS Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=012768686&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Ciba Foundation Symposium on Chemistry and Biology of Pteridines Pteridines |
| subject_GND | (DE-588)1071861417 |
| title | Ciba Foundation Symposium on Chemistry and Biology of Pteridines |
| title_alt | Chemistry and biology of pteridines |
| title_auth | Ciba Foundation Symposium on Chemistry and Biology of Pteridines |
| title_exact_search | Ciba Foundation Symposium on Chemistry and Biology of Pteridines |
| title_full | Ciba Foundation Symposium on Chemistry and Biology of Pteridines ed. G. E. W. Wolstenholme ... |
| title_fullStr | Ciba Foundation Symposium on Chemistry and Biology of Pteridines ed. G. E. W. Wolstenholme ... |
| title_full_unstemmed | Ciba Foundation Symposium on Chemistry and Biology of Pteridines ed. G. E. W. Wolstenholme ... |
| title_short | Ciba Foundation Symposium on Chemistry and Biology of Pteridines |
| title_sort | ciba foundation symposium on chemistry and biology of pteridines |
| topic | Pteridines |
| topic_facet | Pteridines Konferenzschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=012768686&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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