Expressionsregulation löslicher Guanylylcyclase in pulmonalarteriellen Endothelzellen:
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| Main Author: | |
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| Format: | Book |
| Language: | German |
| Published: |
2003
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| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | Würzburg, Univ., Diss., 2004 |
| Physical Description: | 63 S. graph. Darst. |
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Record in the Search Index
| _version_ | 1804130561399193600 |
|---|---|
| adam_text | Inhalt
Abkürzungen
Einleitung 1
NO und seine Wirkungen 1
Die NO-Synthasen 1
Wie sieht die Signalkaskade aus? 2
NO-Inaktivierung 4
Wie wird sGC reguliert? 5
Östrogen 10
Calciumkanalblocker 11
Zytokine 13
LPS 14
TNF-a -...; 15
INF-y 15
Fragestellung 16
Material und Methoden 17
Reagenzien 17
Geräte 19
Computerprogramme 21
Pufferlösungen 22
Homogenisation von Rattengeweben 24
Präparation von pulmonalarteriellen Endothelzellen 25
Vorbereitungen 25
Beschaffung der Arterien 25
Präparation der Zellen 26
Splitten der Zellen 27
Zellernte 27
Proteinbestimmung 28
Bradford 28
Micro-Lowry [124] 29
Gelelektrophorese und Western Blot 30
Gelelektrophorese 30
Westernblot 30
Strippen 32
Durchfuhrung der Versuche 32
oxLDL 33
Cytokin-Mix 33
DETA/NONOate 33
Ca2+-Kanalblocker 34
Ergebnisse 35
Expression von sGC in PPAEC 35
Behandlung der Zellen mit DETA-NO/NOate 36
NOS ffl Knock-out-Mäuse 37
oxLDL 39
Östrogen 40
Zytokine 42
Ca^-Antagonisten 44
Diskussion 47
Zusammenfassung 51
Literatur 52
Danksagung
Lebenslauf
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| author_facet | Helle, Annegret |
| author_role | aut |
| author_sort | Helle, Annegret |
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| building | Verbundindex |
| bvnumber | BV017896660 |
| ctrlnum | (OCoLC)723016519 (DE-599)BVBBV017896660 |
| discipline | Medizin |
| format | Book |
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| id | DE-604.BV017896660 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:22:59Z |
| institution | BVB |
| language | German |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-010734468 |
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| physical | 63 S. graph. Darst. |
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| spelling | Helle, Annegret Verfasser aut Expressionsregulation löslicher Guanylylcyclase in pulmonalarteriellen Endothelzellen von Annegret Helle 2003 63 S. graph. Darst. txt rdacontent n rdamedia nc rdacarrier Würzburg, Univ., Diss., 2004 (DE-588)4113937-9 Hochschulschrift gnd-content HBZ Datenaustausch application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010734468&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | Helle, Annegret Expressionsregulation löslicher Guanylylcyclase in pulmonalarteriellen Endothelzellen |
| subject_GND | (DE-588)4113937-9 |
| title | Expressionsregulation löslicher Guanylylcyclase in pulmonalarteriellen Endothelzellen |
| title_auth | Expressionsregulation löslicher Guanylylcyclase in pulmonalarteriellen Endothelzellen |
| title_exact_search | Expressionsregulation löslicher Guanylylcyclase in pulmonalarteriellen Endothelzellen |
| title_full | Expressionsregulation löslicher Guanylylcyclase in pulmonalarteriellen Endothelzellen von Annegret Helle |
| title_fullStr | Expressionsregulation löslicher Guanylylcyclase in pulmonalarteriellen Endothelzellen von Annegret Helle |
| title_full_unstemmed | Expressionsregulation löslicher Guanylylcyclase in pulmonalarteriellen Endothelzellen von Annegret Helle |
| title_short | Expressionsregulation löslicher Guanylylcyclase in pulmonalarteriellen Endothelzellen |
| title_sort | expressionsregulation loslicher guanylylcyclase in pulmonalarteriellen endothelzellen |
| topic_facet | Hochschulschrift |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010734468&sequence=000002&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
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