The genome of Homo sapiens:
Saved in:
| Format: | Book |
|---|---|
| Language: | English |
| Published: |
Cold Spring Harbor; NY
Cold Spring Harbor Laboratory Press
2003
|
| Series: | Cold Spring Harbor Symposia on Quantitative Biology
68 |
| Subjects: | |
| Online Access: | Inhaltsverzeichnis |
| Item Description: | www.cshl-symposium.org |
| Physical Description: | XXV, 512 S. Ill., graph. Darst. |
| ISBN: | 0879697091 0879697105 |
Staff View
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| adam_text | COLD SPRING HARBOR SYMPOSIA ON QUANTITATIVE BIOLOGY VOLUME LXVIII THE
GENOME OF HOMO SAPIENS WWW.CSHL-SYMPOSIUM.ORG * I. MEETING ORGANIZED BY
BRUCE STILLMAN AND DAVID STEWART COLD SPRING HARBOR LABORATORY PRESS
2003 CONTENTS SYMPOSIUM PARTICIPANTS V FOREWORD XXI HUMAN GENOME
SEQUENCE THE FINISHED GENOME SEQUENCE OF HOMO SAPIENS J.ROGERS 1 THE
HUMAN GENOME: GENES, PSEUDOGENES, AND VARIATION ON CHROMOSOME 7 R.H.
WATERSTON, L. W. HILLIER, L.A. FULTON, R.S. FULTON, T.A. GRAVES, K.H
PEPIN, P. BORK, M. SUYAMA, D. TORRENTS, A.T. CHINWALLA, E.R. MARDIS,
J.D. MCPHERSON, ANDR.K. WILSON 13 MUTATIONAL PROFILING IN THE HUMAN
GENOME R.K. WILSON, T.J. LEY, F.S. COLE, J.D. MILBRANDT, S. CLIFTON, L.
FULTON, G. FEWELL, P. MINX, H. SUN, M. MCLELLAN, C. POHL, AND E.R.
MARDIS 23 ASSESSING THE QUALITY OF FINISHED GENOMIC SEQUENCE J. SCHMUTZ,
J. WHEELER, J. GRIMWOOD, M. DICKSON, AND R.M. MYERS 31 HUMAN
SUBTELOMERIC DNA H. RIETHMAN, A. AMBROSINI, C. CASTANEDA, J.M.
FINKLESTEIN, X.-L. HU, S.PAUL, AND J. WEI 39 GENOME RESEARCH: THE NEXT
GENERATION F. C. COLLINS 49 HUMAN GENETIC VARIATION DNA SEQUENCE
VARIATION OF HOMO SAPIENS D.R. BENTLEY 55 SNP GENOTYPING AND MOLECULAR
HAPLOTYPING OF DNA POOLS P.-Y. KWOKAND M. XIAO 65 HIGHLY PARALLEL SNP
GENOTYPING J.-B. FAN, A. OLIPHANT, R. SHEN, B.G. KERMANI, F. GARCIA,
K.L. GUNDERSON, M. HANSEN, F. STEEMERS, S.L. BUTLER, P. DELOUKAS, L.
GALVER, S. HUNT, C. MCBRIDE, M. BIBIKOVA, T. RUBANO, J. CHEN, E.
WICKHAM, D. DOUCET, W. CHANG, D. CAMPBELL, B. ZHANG, S. KRUGLYAK, D.
BENTLEY, J. HAAS, P. RIGAULT, L. ZHOU, J. STUELPNAGEL, AND M.S. CHEE
69 STRUCTURE OF LINKAGE DISEQUILIBRIUM IN HUMANS: GENOME FACTORS AND
POPULATION STRATIFICATION J. BERTRANPETIT, F. CALAFELL, D. COMAS, A.
GONZDLEZ-NEIRA, AND A. NAVARRO 79 GENOME-WIDE ASSOCIATION OF HAPLOTYPE
MARKERS TO GENE EXPRESSION LEVELS A. WINDEMUTH, M. KUMAR, K. NANDABALAN,
B. KOSHY, C. XU, M. PUNGLIYA, AND R. JUDSON 89 GENETIC VARIATION AND THE
CONTROL OF TRANSCRIPTION C. COTSAPAS, E. CHAN, M. KIRK, M. TANAKA, AND
P. LITTLE 109 GENOME STRUCTURE AND EVOLUTION GENOME-WIDE DETECTION AND
ANALYSIS OF RECENT SEGMENTAL DUPLICATIONS WITHIN MAMMALIAN ORGANISMS
J.A. BAILEY AND E.E. EICHLER 115 THE EFFECTS OF EVOLUTIONARY DISTANCE ON
TWINSCAN, AN ALGORITHM FOR PAIR-WISE COMPARATIVE GENE PREDICTION M.
WANG, J. BUHLER, AND M.R. BRENT 125 LINEAGE-SPECIFIC EXPANSION OF KRAB
ZINC-FINGER TRANSCRIPTION FACTOR GENES: IMPLICATIONS FOR THE EVOLUTION
OF VERTEBRATE REGULATORY NETWORKS A.T. HAMILTON, S. HUNTLEY, J. KIM, E.
BRANSCOMB, AND L. STUBBS 131 SEQUENCE ORGANIZATION AND FUNCTIONAL
ANNOTATION OF HUMAN CENTROMERES M.K. RUDD, M.G. SCHUELER, AND H.F.
WILLARD 141 GENOMICS OF NON-HUMAN SPECIES EVOLUTIONARY STRATEGIES OF
HUMAN PATHOGENS J. PARKHILL AND N. THOMSON 151 GENE EXPRESSION PROFILING
OF CELLS, TISSUES, AND DEVELOPMENTAL STAGES OF THE NEMATODE C. ELEGANS
S.J. MCKAY, R. JOHNSEN, J. KHATTRA, J. ASANO, D.L. BAILLIE, S. CHAN, N.
DUBE, L. FANG, B. GOSZCZYNSKI, E. HA, E. HALFNIGHT, R. HOLLEBAKKEN, P.
HUANG, K. HUNG, V. JENSEN, S.J.M. JONES, H. KAI, D. LI, A. MAH, M.
MARRA, J. MCGHEE, R. NEWBURY, A. POUZYREV, D.L. RIDDLE, E. SONNHAMMER,
H. TIDN, D. TU, J.R. TYSON, G. VATCHER? A. WARNER, K. WONG, Z. ZHAO, AND
D.G. MOERMAN 159 XXM XXIV CONTENTS BUILDING COMPARATIVE MAPS USING 1.5X
SEQUENCE COVERAGE: HUMAN CHROMOSOME LP AND THE CANINE GENOME R. GUYON,
E.F. KIRKNESS, T.D. LORENTZEN, C. HITTE, K.E. COMSTOCK, P. QUIGNON, T.
DERRIEN, C. ANDRE, CM. FRASER, F. GALIBERT, AND E.A. OSTRANDER 17 1
POSITIONAL IDENTIFICATION OF STRUCTURAL AND REGULATORY QUANTITATIVE
TRAIT NUCLEOTIDES IN DOMESTIC ANIMAL SPECIES M. GEORGES AND L. ANDERSSON
, 179 EVOLVING METHODS FOR THE ASSEMBLY OF LARGE GENOMES R.A. GIBBS AND
G.M. WEINSTOCK 189 MOUSE GENOME ENCYCLOPEDIA PROJECT Y. HAYASHIZAKI 195
BIOINFORMATICS AND ANNOTATION DNA SEQUENCE ASSEMBLY AND MULTIPLE
SEQUENCE ALIGNMENT BY AN EULERIAN PATH APPROACH Y. ZHANG AND M.S.
WATERMAN 205 ENSEMBL: A GENOME INFRASTRUCTURE E. BIRNEY AND THE ENSEMBL
TEAM 213 PREDICTION, ANNOTATION, AND ANALYSIS OF HUMAN PROMOTERS M. Q.
ZHANG 217 ONTOLOGIES FOR BIOLOGISTS: A COMMUNITY MODEL FOR THE
ANNOTATION OF GENOMIC DATA M. ASHBURNER, CJ. MUNGALL, AND S.E. LEWIS
227 THE GENOME KNOWLEDGEBASE: A RESOURCE FOR BIOLOGISTS AND
BIOINFORMATICISTS G. JOSHI-TOPE, I. VASTRIK, G.R. GOPINATH, L. MATTHEWS,
E. SCHMIDT, M. GILLESPIE, P. D EUSTACHIO, B. JASSAL, S. LEWIS, G. WU, E.
BIRNEY, AND L. STEIN 237 COMPARING GENOMES THE SHARE OF HUMAN GENOMIC
DNA UNDER SELECTION ESTIMATED FROM HUMAN-MOUSE GENOMIC ALIGNMENTS F.
CHIAROMONTE, R.J. WEBER, KM. ROSKIN, M. DIEKHANS, W.J. KENT, AND D.
HAUSSLER . 245 DETECTING HIGHLY CONSERVED REGIONS OF THE HUMAN GENOME BY
MULTISPECIES SEQUENCE COMPARISONS E.H. MARGULIES, NISC COMPARATIVE
SEQUENCING PROGRAM, AND E.D. GREEN 255 COMPARATIVE ANALYSIS OF HUMAN
CHROMOSOME 22QL I.L-QL2.3 WITH SYNTENIC REGIONS IN THE CHIMPANZEE,
BABOON, BOVINE, MOUSE, PUFFERFISH, AND ZEBRAFISH GENOMES B.A. ROE, C.
LAU, S. OOMMEN, J. LI, A. HUA, H.S. LAI, S. KENTON, J. WHITE, AND H.
WANG 265 GENOME-WIDE ANALYSES BASED ON COMPARATIVE GENOMICS O. JAILLON,
J.-M. AURY, H. ROEST CROLLIUS, M. SALANOUBAT, P. WINCKER, C. DOSSAT, V.
CASTELLI, N. BOUDET, S. SAMAIR, R. ECKENBERG, S. BONNEVAL, W. SAURIN, C.
SCARPELLI, V. SCHDCHTER, ANDJ. WEISSENBACH 275 COMPARATIVE GENOMIC TOOLS
FOR EXPLORING THE HUMAN GENOME /. OVCHARENKO AND G.G. LOOTS 283
EVOLUTION OF EUKARYOTIC GENE REPERTOIRE AND GENE STRUCTURE: DISCOVERING
THE UNEXPECTED DYNAMICS OF GENOME EVOLUTION I.B. ROGOZIN, V.N. BABENKO,
N.D. FEDOROVA, J.D. JACKSON, A.R. JACOBS, D.M. KRYLOV, K.S. MAKAROVA, R.
MAZUMDER, S.L. MEKHEDOV, B.G. MIRKIN, A.N. NIKOLSKAYA, B.S. RAO, S.
SMIRNOV, A. V. SOROKIN, A. V. SVERDLOV, S. VASUDEVAN, Y.I. WOLF, J.J.
YIN, D.A. NATALE, AND E. V. KOONIN 293 COMPARATIVE FUNCTIONAL GENOMICS
HUMAN-MOUSE COMPARATIVE GENOMICS: SUCCESSES AND FAILURES TO REVEAL
FUNCTIONAL REGIONS OF THE HUMAN GENOME L.A. PENNACCHIO, N. BAROUKH, AND
E.M. RUBIN 303 HIGH-THROUGHPUT MOUSE KNOCKOUTS PROVIDE A FUNCTIONAL
ANALYSIS OF THE GENOME CJ. FRIDDLE, A. ABUIN, R. RAMIREZ-SOLIS, L.J.
RICHTER, B.C. BUXTON, J. EDWARDS, R.A. FINCH, A. GUPTA, G. HANSEN, K.H.
HOLT, Y. HU, W. HUANG, C. JAING, B. W. KEY, JR., P. KIPP, B. KOHLHAUFF
Z.-Q. MA, D. MARKESICH, M. NEWHOUSE, T. PERRY, K.A. PLATT, D.G. POTTER,
N. QIAN, J. SHAW, J. SCHRICK, Z.-Z. SHI, M.J. SPARKS, D. TRAN, E.R.
WANN, W. WALKE, J.D. WALLACE, N. XU, Q. ZHU, C PERSON, A.T. SANDS,
ANDB.P. ZAMBROWICZ 311 IDENTIFICATION OF NOVEL FUNCTIONAL ELEMENTS IN
THE HUMAN GENOME Z. LIAN, G. EUSKIRCHEN, J. RINN, R. MARTONE, P.
BERTONE, S. HARTMAN, T. ROYCE, K. NELSON, F. SAYWARD, N. LUSCOMBE, J.
YANG, J.-L. LI, P. MILLER, A.E. URBAN, M. GERSTEIN, S. WEISSMAN, AND M.
SNYDER 317 HIGH-RESOLUTION HUMAN GENOME SCANNING USING WHOLE-GENOME BAC
ARRAYS J. LI, T. JIANG, B. BEJJANI, E. RAJCAN-SEPAROVIC, AND W.-W. CAI
323 ANNOTATION OF NOVEL PROTEINS UTILIZING A FUNCTIONAL GENOME SHOTGUN
COUPLED WITH HIGH-THROUGHPUT PROTEIN INTERACTION MAPPING J.A. MALEK,
J.M. WIERZBOWSKI, G.A. DASCH, M.E. EREMEVA, P.J. MCEWAN, AND KJ.
MCKERNAN 331 GLOBAL PREDICTIONS AND TESTS OF ERYTHROID REGULATORY
REGIONS R.C. HARDISON, F. CHIAROMONTE, D. KOLBE, H. WANG, H.
PETRYKOWSKA, L. ELNITSKI, S. YANG, B. GIARDINE, Y. ZHANG, C. RIEMER, S.
SCHWARTZ, D. HAUSSLER, KM: ROSKIN, R.J. WEBER, M. DIEKHANS, W.J. KENT,
M.J. WEISS, J. WELCH, AND W. MILLER - 335 CONTENTS SYSTEMS APPROACHES
APPLIED TO THE STUDY OF SACCHAROMYCES CEREVISIAE AND HALOBACTERIUM SP.
A.D. WESTON, N.S. BALIGA, R. BONNEAU, AND L. HOOD 345 GENETIC VARIATION
AND DISEASE IMPLICATIONS OF GENOMICS FOR PUBLIC HEALTH: THE ROLE OF
GENETIC EPIDEMIOLOGY K.R. MERIKANGAS 359 A MODEL SYSTEM FOR IDENTIFYING
GENES UNDERLYING COMPLEX TRAITS D. DRAYNA, U.-K. KIM, H COON, E.
JORGENSON, N. RISCH, AND M. LEPPERT 365 GENOMIC VARIATION IN MULTIGENIC
TRAITS: HIRSCHSPRUNG DISEASE A.S. MCCALLION, E.S. EMISON, C.S. KASHUK,
R.T. BUSH, M. KENTON, M.M. CARRASQUILLO, K.W. JONES, G.C. KENNEDY, M.E.
PORTNOY, E.D. GREEN, AND A. CHAKRAVARTI 373 GENETICS OF SCHIZOPHRENIA
AND BIPOLAR AFFECTIVE DISORDER: STRATEGIES TO IDENTIFY CANDIDATE GENES
D.J. PORTEOUS, KL. EVANS, J.K MILLAR, B.S. PICKARD, P.A. THOMSON, R.
JAMES, S. MACGREGOR, N.R. WRAY, P.M. VISSCHER, W.J. MUIR, AND D.H.
BLACKWOOD 383 THE GENETICS OF COMMON DISEASES: 10 MILLION TIMES AS HARD
D.B. GOLDSTEIN, G.L. CAVALLERI, AND K.R. AHMADI 395 GENETICS OF
QUANTITATIVE VARIATION IN HUMAN GENE EXPRESSION V.G. CHEUNG, K.-Y. JEN,
T. WEBER, M. MORLEY, J.L. DEVLIN, KG. EWENS, ANDR.S. SPIELMAN 403
REGULATION OF CC-SYNUCLEIN EXPRESSION: IMPLICATIONS FOR PARKINSON S
DISEASE O. CHIBA-FALEK AND R.L. NUSSBAUM 409 GENOME BIOLOGY AND DISEASE
GENOMIC PERSPECTIVE AND CANCER D. BOTSTEIN ALL CHROMOSOME 21 AND DOWN
SYNDROME: THE POST-SEQUENCE ERA S.E. ANTONARAKIS, A. REYMOND, R. LYLE,
S. DEUTSCH, ANDE.T. DERMITZAKIS 425 HARVESTING THE GENOME S BOUNTY:
INTEGRATIVE GENOMICS P. JORGENSEN, B.-J. BREITKREUTZ, K. BREITKREUTZ, C.
STARK, G. LIU, M. COOK, J. SHAWM, J.L. NISHIKAWA, T. KETELA, D. BELLOWS,
A. BREITKREUTZ, I. RUPES, L. BOUCHER, D. DEWAR, M. VO, M. ANGELI, T.
REGULY, A. TONG, B. ANDREWS, C. BOONE, AND M. TYERS 431 GENOMIC
DISORDERS: GENOMIC ARCHITECTURE RESULTS IN SUSCEPTIBILITY TO DNA
REARRANGEMENTS CAUSING COMMON HUMAN TRAITS P. STANKIEWICZ, K INOUE, W.
BI, K. WALZ, S.-S. PARK, N. KUROTAKI, CJ. SHAW, P. FONSECA, J. YAN, J.A.
LEE, M. KHAJAVI, ANDJ.R. LUPSKI 445 HUMAN EVOLUTION HUMAN VERSUS
CHIMPANZEE CHROMOSOME-WIDE SEQUENCE COMPARISON AND ITS EVOLUTIONARY
IMPLICATION Y. SAKAKI, H WATANABE, T. TAYLOR, M. HATTORI, A. FUJIYAMA,
A. TOYODA, Y. KUROKI, T ITOH, N. SAITOU, S. OOTA, C.-G. KIM, T. KITANO,
H. LEHRACH, M.-L. YASPO, R. SUDBRAK, A. KAHLA, R. REINHARDT, M. KUBE, M.
PLATZER, S. TAENZER, P. GALGOCZY, A. KEL, H. BLOECKER, M. SCHARFE, G.
NORDSIEK, I. HELLMANN, P. KHAITOVICH, S. PDABO, Z. CHEN, S.-Y. WANG,
S.-X. REN, X.-L. ZHANG, H.-J. ZHENG, G.-F. ZHU, B.-F. WANG, G.-P. ZHAO,
S.-F. TSAI, K. WU, T.-T. LIU, K.-J. HSIAO, H.-S. PARK, Y.-S. LEE, J.-E.
CHEONG, AND S.-H. CHOI (THE CHIMPANZEE CHROMOSOME 22 SEQUENCING
CONSORTIUM) 455 NOVEL TRANSCRIPTIONAL UNITS AND UNCONVENTIONAL GENE
PAIRS IN THE HUMAN GENOME: TOWARD A SEQUENCE-LEVEL BASIS FOR
PRIMATE-SPECIFIC PHENOTYPES? L. LIPOVICH AND M.-C. KING 461 POSITIVE
SELECTION- IN THE HUMAN GENOME INFERRED FROM HUMAN-CHIMP-MOUSE
ORTHOLOGOUS GENE ALIGNMENTS A.G. CLARK, S. GLANOWSKI, R. NIELSEN, P.
THOMAS, A. KEJARIWAL, M.J. TODD, D.M. TANENBAUM, D. CIVELLO, F. LU, B.
MURPHY, S. FERRIERA, G. WANG, X. ZHENG, TJ. WHITE, JJ. SNINSKY, M.D.
ADAMS, ANDM. CARGILL ALL MTDNA VARIATION, CLIMATIC ADAPTATION,
DEGENERATIVE DISEASES, AND LONGEVITY D. C. WALLACE, E. RUIZ-PESINI, AND
D. MISHMAR 479 INFERRING HUMAN HISTORY: CLUES FROM Y-CHROMOSOME
HAPLOTYPES P.A. UNDERHILL 487 SUMMARY; THE NEW QUANTITATIVE BIOLOGY M.
V. OLSON 495 AUTHOR INDEX 503 SUBJECT INDEX 505
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| genre | (DE-588)1071861417 Konferenzschrift 2003 Cold Spring Habor NY gnd-content |
| genre_facet | Konferenzschrift 2003 Cold Spring Habor NY |
| id | DE-604.BV017645015 |
| illustrated | Illustrated |
| indexdate | 2024-07-09T19:20:18Z |
| institution | BVB |
| isbn | 0879697091 0879697105 |
| language | English |
| oai_aleph_id | oai:aleph.bib-bvb.de:BVB01-010613072 |
| oclc_num | 56018556 |
| open_access_boolean | |
| owner | DE-355 DE-BY-UBR DE-20 DE-29T DE-12 DE-11 |
| owner_facet | DE-355 DE-BY-UBR DE-20 DE-29T DE-12 DE-11 |
| physical | XXV, 512 S. Ill., graph. Darst. |
| publishDate | 2003 |
| publishDateSearch | 2003 |
| publishDateSort | 2003 |
| publisher | Cold Spring Harbor Laboratory Press |
| record_format | marc |
| series | Cold Spring Harbor Symposia on Quantitative Biology |
| series2 | Cold Spring Harbor Symposia on Quantitative Biology |
| spelling | The genome of Homo sapiens Meeting organized by Bruce Stillman ... Cold Spring Harbor; NY Cold Spring Harbor Laboratory Press 2003 XXV, 512 S. Ill., graph. Darst. txt rdacontent n rdamedia nc rdacarrier Cold Spring Harbor Symposia on Quantitative Biology 68 www.cshl-symposium.org Human Genome Project Congresses Genomas (congressos) larpcal Génome humain - Congrès Génomes - Congrès Génomique - Congrès Genome Congresses Genome, Human Congresses Genomes Congresses Genomics Congresses Human gene mapping Congresses Human genetics Congresses Human genome Congresses Humangenetik (DE-588)4072653-8 gnd rswk-swf Genom (DE-588)4156640-3 gnd rswk-swf Mensch (DE-588)4038639-9 gnd rswk-swf (DE-588)1071861417 Konferenzschrift 2003 Cold Spring Habor NY gnd-content Mensch (DE-588)4038639-9 s Genom (DE-588)4156640-3 s DE-604 Humangenetik (DE-588)4072653-8 s b DE-604 Stillman, Bruce Sonstige oth Cold Spring Harbor Symposia on Quantitative Biology 68 (DE-604)BV010931512 68 HEBIS Datenaustausch Darmstadt application/pdf http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010613072&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA Inhaltsverzeichnis |
| spellingShingle | The genome of Homo sapiens Cold Spring Harbor Symposia on Quantitative Biology Human Genome Project Congresses Genomas (congressos) larpcal Génome humain - Congrès Génomes - Congrès Génomique - Congrès Genome Congresses Genome, Human Congresses Genomes Congresses Genomics Congresses Human gene mapping Congresses Human genetics Congresses Human genome Congresses Humangenetik (DE-588)4072653-8 gnd Genom (DE-588)4156640-3 gnd Mensch (DE-588)4038639-9 gnd |
| subject_GND | (DE-588)4072653-8 (DE-588)4156640-3 (DE-588)4038639-9 (DE-588)1071861417 |
| title | The genome of Homo sapiens |
| title_auth | The genome of Homo sapiens |
| title_exact_search | The genome of Homo sapiens |
| title_full | The genome of Homo sapiens Meeting organized by Bruce Stillman ... |
| title_fullStr | The genome of Homo sapiens Meeting organized by Bruce Stillman ... |
| title_full_unstemmed | The genome of Homo sapiens Meeting organized by Bruce Stillman ... |
| title_short | The genome of Homo sapiens |
| title_sort | the genome of homo sapiens |
| topic | Human Genome Project Congresses Genomas (congressos) larpcal Génome humain - Congrès Génomes - Congrès Génomique - Congrès Genome Congresses Genome, Human Congresses Genomes Congresses Genomics Congresses Human gene mapping Congresses Human genetics Congresses Human genome Congresses Humangenetik (DE-588)4072653-8 gnd Genom (DE-588)4156640-3 gnd Mensch (DE-588)4038639-9 gnd |
| topic_facet | Human Genome Project Congresses Genomas (congressos) Génome humain - Congrès Génomes - Congrès Génomique - Congrès Genome Congresses Genome, Human Congresses Genomes Congresses Genomics Congresses Human gene mapping Congresses Human genetics Congresses Human genome Congresses Humangenetik Genom Mensch Konferenzschrift 2003 Cold Spring Habor NY |
| url | http://bvbr.bib-bvb.de:8991/F?func=service&doc_library=BVB01&local_base=BVB01&doc_number=010613072&sequence=000001&line_number=0001&func_code=DB_RECORDS&service_type=MEDIA |
| volume_link | (DE-604)BV010931512 |
| work_keys_str_mv | AT stillmanbruce thegenomeofhomosapiens |